SG11201906321WA - Novel process for preparing water soluble forskolin - Google Patents

Novel process for preparing water soluble forskolin

Info

Publication number
SG11201906321WA
SG11201906321WA SG11201906321WA SG11201906321WA SG11201906321WA SG 11201906321W A SG11201906321W A SG 11201906321WA SG 11201906321W A SG11201906321W A SG 11201906321WA SG 11201906321W A SG11201906321W A SG 11201906321WA SG 11201906321W A SG11201906321W A SG 11201906321WA
Authority
SG
Singapore
Prior art keywords
international
forskolin
pct
water soluble
novel process
Prior art date
Application number
SG11201906321WA
Other languages
English (en)
Inventor
Andreas Kubin
Original Assignee
Scipharm Sarl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scipharm Sarl filed Critical Scipharm Sarl
Publication of SG11201906321WA publication Critical patent/SG11201906321WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyrane Compounds (AREA)
SG11201906321WA 2017-01-09 2018-01-09 Novel process for preparing water soluble forskolin SG11201906321WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17150644 2017-01-09
PCT/EP2018/050447 WO2018127600A1 (en) 2017-01-09 2018-01-09 Novel process for preparing water soluble forskolin

Publications (1)

Publication Number Publication Date
SG11201906321WA true SG11201906321WA (en) 2019-08-27

Family

ID=57868023

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201906321WA SG11201906321WA (en) 2017-01-09 2018-01-09 Novel process for preparing water soluble forskolin

Country Status (17)

Country Link
US (1) US11234957B2 (da)
EP (1) EP3565602B1 (da)
JP (1) JP7138643B2 (da)
KR (1) KR102583356B1 (da)
CN (1) CN110325217B (da)
CY (1) CY1124325T1 (da)
DK (1) DK3565602T3 (da)
ES (1) ES2872223T3 (da)
HR (1) HRP20210863T1 (da)
HU (1) HUE054617T2 (da)
LT (1) LT3565602T (da)
PL (1) PL3565602T3 (da)
PT (1) PT3565602T (da)
RS (1) RS61915B1 (da)
SG (1) SG11201906321WA (da)
SI (1) SI3565602T1 (da)
WO (1) WO2018127600A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI4093374T3 (en) 2020-01-23 2024-02-06 Scipharm S A R L A complex consisting of 7-deacetylforskolin and PVP

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU199444B (en) 1985-09-10 1990-02-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 7-isopropoxy-isoflavone-cyclodextrene inclusion complex and pharmaceutical compositions therefrom
JP3040015B2 (ja) * 1991-08-21 2000-05-08 日研化学株式会社 フォルスコリンの包接化合物
IT1294205B1 (it) 1997-07-23 1999-03-24 Farmigea Spa Procedimento per la solubilizzazione in acqua e in veicoli acquosi di sostanze farmacologicamente attive
US6884885B2 (en) * 2000-12-21 2005-04-26 Cerestar Holding B.V. Production of cyclodextrin complexes
GB0127677D0 (en) * 2001-11-19 2002-01-09 Vianex S A Inclusion complex
JP4982656B2 (ja) 2003-05-20 2012-07-25 東洋精糖株式会社 水可溶性イソフラボン組成物およびその製造方法並びにその用途
US6960300B2 (en) 2003-09-08 2005-11-01 Sami Labs Limited Process for preparing water soluble diterpenes and their applications
PT1793862E (pt) * 2004-08-02 2011-04-08 Chiesi Farma Spa Processo para a preparação de um composto de inclusão de piroxicam:beta-ciclodextrina
BRPI0705319A2 (pt) * 2007-07-23 2009-07-21 Uniao Brasileira De Educacao Manedora Da Pucrs processo para obtenção de um complexo solúvel de resveratrol e/ou seus derivados; complexo de resveratrol e/ou seus derivados; composição nutracêutica
EP2253627A1 (en) 2009-05-21 2010-11-24 ERREGIERRE S.p.A. Inclusion complex of raloxifene hydrochloride and beta-cyclodextrin.
CN103768616B (zh) * 2014-01-08 2015-08-05 中国科学院昆明植物研究所 毛萼乙素环糊精包合物、含有该包合物的药物组合物、其制备方法及应用

Also Published As

Publication number Publication date
CY1124325T1 (el) 2022-07-22
WO2018127600A1 (en) 2018-07-12
KR102583356B1 (ko) 2023-09-26
US11234957B2 (en) 2022-02-01
SI3565602T1 (sl) 2021-07-30
PL3565602T3 (pl) 2021-09-13
CN110325217A (zh) 2019-10-11
JP7138643B2 (ja) 2022-09-16
JP2020505339A (ja) 2020-02-20
EP3565602A1 (en) 2019-11-13
HUE054617T2 (hu) 2021-09-28
KR20190107690A (ko) 2019-09-20
ES2872223T3 (es) 2021-11-02
CN110325217B (zh) 2023-08-08
PT3565602T (pt) 2021-05-26
LT3565602T (lt) 2021-06-25
US20210145791A1 (en) 2021-05-20
EP3565602B1 (en) 2021-03-03
DK3565602T3 (da) 2021-06-07
HRP20210863T1 (hr) 2021-08-20
RS61915B1 (sr) 2021-06-30

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