DE69917618D1 - Zusammensetzung mit kontrollierter wirkstoff-freisetzung - Google Patents
Zusammensetzung mit kontrollierter wirkstoff-freisetzungInfo
- Publication number
- DE69917618D1 DE69917618D1 DE69917618T DE69917618T DE69917618D1 DE 69917618 D1 DE69917618 D1 DE 69917618D1 DE 69917618 T DE69917618 T DE 69917618T DE 69917618 T DE69917618 T DE 69917618T DE 69917618 D1 DE69917618 D1 DE 69917618D1
- Authority
- DE
- Germany
- Prior art keywords
- composition
- matrix
- water
- active substance
- aqueous medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98610009 | 1998-04-03 | ||
| EP98610009 | 1998-04-03 | ||
| PCT/DK1999/000174 WO1999051208A1 (en) | 1998-04-03 | 1999-03-25 | Controlled release composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69917618D1 true DE69917618D1 (de) | 2004-07-01 |
| DE69917618T2 DE69917618T2 (de) | 2005-06-23 |
Family
ID=8235847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69917618T Expired - Lifetime DE69917618T2 (de) | 1998-04-03 | 1999-03-25 | Zusammensetzung mit kontrollierter wirkstoff-freisetzung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7883722B2 (de) |
| EP (1) | EP1067910B1 (de) |
| JP (1) | JP4533531B2 (de) |
| AT (1) | ATE267589T1 (de) |
| AU (1) | AU3024399A (de) |
| CA (1) | CA2327685C (de) |
| DE (1) | DE69917618T2 (de) |
| DK (1) | DK1067910T3 (de) |
| ES (1) | ES2221370T3 (de) |
| WO (1) | WO1999051208A1 (de) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3024399A (en) | 1998-04-03 | 1999-10-25 | Bm Research A/S | Controlled release composition |
| EP1429739A1 (de) | 2001-09-21 | 2004-06-23 | Egalet A/S | Polymer-freigabe-system |
| WO2003024430A1 (en) | 2001-09-21 | 2003-03-27 | Egalet A/S | Morphine polymer release system |
| EP1929998A3 (de) | 2001-09-21 | 2008-11-26 | Egalet A/S | Festdispersionen mit gesteuerter Freisetzung von Carvedilol |
| GB0203296D0 (en) | 2002-02-12 | 2002-03-27 | Glaxo Group Ltd | Novel composition |
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| US8637512B2 (en) | 2002-07-29 | 2014-01-28 | Glaxo Group Limited | Formulations and method of treatment |
| GB0222612D0 (en) * | 2002-09-30 | 2002-11-06 | Univ Gent | Controlled delivery system for bioactive substances |
| MY148805A (en) * | 2002-10-16 | 2013-05-31 | Takeda Pharmaceutical | Controlled release preparation |
| AU2003275953A1 (en) | 2002-11-08 | 2004-06-07 | Egalet A/S | Controlled release carvedilol compositions |
| EP1610768B1 (de) | 2003-03-26 | 2008-07-02 | Egalet A/S | Matrixzubereitungen für die kontrollierte darreichung von arzneistoffen |
| EP1610767B1 (de) | 2003-03-26 | 2011-01-19 | Egalet A/S | Morphin-system mit kontrollierter freisetzung |
| CN102525993B (zh) | 2003-04-24 | 2017-04-12 | 佳高泰克有限公司 | 具有限定内核几何形状的缓释片剂 |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| GB0318824D0 (en) * | 2003-08-11 | 2003-09-10 | Glaxo Group Ltd | Novel composition |
| DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| US20060078623A1 (en) * | 2004-08-13 | 2006-04-13 | Emisphere Technologies, Inc. | Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent |
| DE102004043863A1 (de) | 2004-09-10 | 2006-03-16 | Nitec Pharma Ag | Tabletten mit orts- und zeitgesteuerter Wirkstofffreisetzung im Gastrointestinum |
| SI2801354T1 (sl) * | 2004-10-08 | 2017-07-31 | Forward Pharma A/S | Farmacevtske sestave z nadzorovanim sproščanjem, ki zajemajo ester fumarne kisline |
| US8481565B2 (en) * | 2004-12-27 | 2013-07-09 | Eisai R&D Management Co., Ltd. | Method for stabilizing anti-dementia drug |
| US20090208579A1 (en) * | 2004-12-27 | 2009-08-20 | Eisai R & D Management Co., Ltd. | Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same |
| US20060246003A1 (en) * | 2004-12-27 | 2006-11-02 | Eisai Co. Ltd. | Composition containing anti-dementia drug |
| US20060280789A1 (en) * | 2004-12-27 | 2006-12-14 | Eisai Research Institute | Sustained release formulations |
| DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| CA2611081C (en) * | 2005-06-03 | 2016-05-31 | Egalet A/S | A drug delivery system for delivering active substances dispersed in a dispersion medium |
| SG174026A1 (en) | 2006-08-03 | 2011-09-29 | Nitec Pharma Ag | Delayed-release glucocorticoid treatment of rheumatoid disease |
| EP1920767A1 (de) * | 2006-11-09 | 2008-05-14 | Abbott GmbH & Co. KG | Schmelzverarbeitete Darreichungsform mit Imatinib |
| EP2104493A2 (de) * | 2007-01-16 | 2009-09-30 | Egalet A/S | Verwendung i) eines polyglycols und n) einer wirkstoffsubstanz zur herstellung einer pharmazeutischen zusammensetzung i) zur abschwächung des risikos alkoholbedingten dose-dumpings und/oder ii) zur reduzierung des risikos eines medikamentenmissbrauchs |
| AU2008258596B2 (en) | 2007-06-04 | 2013-02-14 | Egalet Ltd | Controlled release pharmaceutical compositions for prolonged effect |
| CA2713128C (en) | 2008-01-25 | 2016-04-05 | Gruenenthal Gmbh | Pharmaceutical dosage form |
| WO2009109194A2 (en) | 2008-02-29 | 2009-09-11 | Ferrosan A/S | Device for promotion of hemostasis and/or wound healing |
| BRPI0912014A2 (pt) | 2008-05-09 | 2019-03-06 | Grünenthal GmbH | processo para a preparação de uma formulação em pó intermediária e uma forma de dosagem sólida final sob uso de uma etapa de congelamento por atomização |
| CA2734095A1 (en) * | 2008-08-14 | 2010-02-18 | Bioneer A/S | Coated tablets with a remaining degradation surface over the time |
| NZ594207A (en) | 2009-02-06 | 2013-03-28 | Egalet Ltd | Immediate release composition resistant to abuse by intake of alcohol |
| ES2607209T3 (es) | 2009-02-06 | 2017-03-29 | Egalet Ltd. | Composiciones farmacéuticas resistentes al abuso |
| US9555002B2 (en) * | 2009-05-13 | 2017-01-31 | Basf Se | Solid pharmaceutical preparations containing copolymers based on polyethers combined with poorly water-soluble polymers |
| WO2010149169A2 (en) | 2009-06-24 | 2010-12-29 | Egalet A/S | Controlled release formulations |
| RU2015138422A (ru) | 2009-07-22 | 2018-12-25 | Грюненталь Гмбх | Стабильная при окислении, прочная на излом лекарственная форма |
| CN102573805A (zh) | 2009-07-22 | 2012-07-11 | 格吕伦塔尔有限公司 | 热熔挤出的控制释放剂型 |
| TW201132646A (en) * | 2010-02-22 | 2011-10-01 | Daiichi Sankyo Co Ltd | Oral solid extended release dosage form |
| US20130029030A1 (en) | 2010-03-15 | 2013-01-31 | Kristian Larsen | Method for promotion of hemostasis and/or wound healing |
| KR101940207B1 (ko) | 2010-05-12 | 2019-01-18 | 스펙트럼 파마슈티컬즈 인크 | 란탄 카보네이트 하이드록사이드, 란탄 옥시카보네이트 및 이들의 제조 및 사용 방법 |
| NZ607392A (en) | 2010-09-02 | 2015-03-27 | Gruenenthal Chemie | Tamper resistant dosage form comprising inorganic salt |
| BR112013005234A2 (pt) | 2010-09-02 | 2016-05-03 | Gruenenthal Gmbh | forma de dosagem resistente à violação compreendendo um polímero aniônico. |
| PE20141638A1 (es) | 2011-07-29 | 2014-11-22 | Gruenenthal Chemie | Tableta a prueba de manipulacion que proporciona liberacion de farmaco inmediato |
| RS56527B1 (sr) | 2011-07-29 | 2018-02-28 | Gruenenthal Gmbh | Tableta za trenutno oslobađanje leka rezistentna na zloupotrebu |
| MX356421B (es) | 2012-02-28 | 2018-05-29 | Gruenenthal Gmbh | Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico. |
| JP6241624B2 (ja) | 2012-03-06 | 2017-12-06 | フェロサン メディカル デバイシーズ エイ/エス | 止血ペーストを収容する加圧容器 |
| DK2838512T3 (en) | 2012-04-18 | 2018-11-19 | Gruenenthal Gmbh | MANIPULATED AND DOSAGE DUMPED PHARMACEUTICAL DOSAGE FORM |
| US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
| CN104349797B (zh) | 2012-06-12 | 2017-10-27 | 弗罗桑医疗设备公司 | 干止血组合物 |
| US9549899B2 (en) | 2012-07-06 | 2017-01-24 | Egalet Ltd. | Abuse deterrent pharmaceutical compositions for controlled release |
| JP6445537B2 (ja) | 2013-05-29 | 2018-12-26 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 1個または複数の粒子を含有する改変防止(tamper−resistant)剤形 |
| AR096439A1 (es) | 2013-05-29 | 2015-12-30 | Gruenenthal Gmbh | Forma de dosificación resistente al uso indebido que contiene una o más partículas |
| EP3010419B1 (de) | 2013-06-21 | 2020-05-20 | Ferrosan Medical Devices A/S | Vakuumerweiterte trockenzusammensetzung und spritze zum zurückhalten davon |
| US10624862B2 (en) | 2013-07-12 | 2020-04-21 | Grünenthal GmbH | Tamper-resistant dosage form containing ethylene-vinyl acetate polymer |
| AU2014356581C1 (en) | 2013-11-26 | 2020-05-28 | Grunenthal Gmbh | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
| EP3079731B1 (de) | 2013-12-11 | 2018-08-08 | Ferrosan Medical Devices A/S | Trockenzusammensetzung mit extrusionsverstärker |
| WO2015091352A1 (en) | 2013-12-16 | 2015-06-25 | Grünenthal GmbH | Tamper resistant dosage form with bimodal release profile manufactured by co-extrusion |
| JP6521874B2 (ja) * | 2014-02-12 | 2019-05-29 | 沢井製薬株式会社 | フィルムコーティングされた口腔内崩壊錠 |
| MX2016014738A (es) | 2014-05-12 | 2017-03-06 | Gruenenthal Gmbh | Formulacion en capsula de liberacion inmediata resistente a alteraciones que comprende tapentadol. |
| MX2016015417A (es) | 2014-05-26 | 2017-02-22 | Gruenenthal Gmbh | Multiparticulas protegidas contra vertido de dosis etanolico. |
| JP6726852B2 (ja) | 2014-10-13 | 2020-07-22 | フェッローサン メディカル ディバイス エー/エス | 止血および創傷治癒に使用するための乾燥組成物 |
| RU2705905C2 (ru) | 2014-12-24 | 2019-11-12 | Ферросан Медикал Дивайсиз А/С | Шприц для удерживания и смешивания первого и второго веществ |
| JP2018517676A (ja) | 2015-04-24 | 2018-07-05 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 即時放出および溶媒抽出に対する耐性を有する改変防止製剤 |
| AU2016290433B2 (en) | 2015-07-03 | 2018-05-24 | Ferrosan Medical Devices A/S | Syringe for mixing two components and for retaining a vacuum in a storage condition |
| AU2016319203A1 (en) | 2015-09-10 | 2018-02-22 | Grünenthal GmbH | Protecting oral overdose with abuse deterrent immediate release formulations |
| CN112368028A (zh) | 2018-05-09 | 2021-02-12 | 弗罗桑医疗设备公司 | 用于制备止血组合物的方法 |
Family Cites Families (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1018456A (en) | 1972-06-26 | 1977-10-04 | Hans Lowey | Prolonged release lozenges |
| US4330338A (en) * | 1978-10-02 | 1982-05-18 | Purdue Research Foundation | Pharmaceutical coating composition, and preparation and dosages so coated |
| US4389393A (en) * | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
| DE3320583A1 (de) * | 1983-06-08 | 1984-12-13 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue galenische zubereitungsformen von oralen antidiabetika und verfahren zu ihrer herstellung |
| AU591171B2 (en) | 1983-11-02 | 1989-11-30 | Alza Corporation | Dispenser for delivering thermo-responsive composition |
| US4844984A (en) * | 1984-03-19 | 1989-07-04 | Alza Corporation | Dispensing system with means for increasing delivery of beneficial agent from the system |
| JPH0246008B2 (ja) * | 1984-06-01 | 1990-10-12 | Takada Seiyaku Kk | Nifuejipinjizokuseiseizainoseizohoho |
| GB2170104A (en) | 1985-01-30 | 1986-07-30 | Warner Lambert Co | Coated pharmaceutical dosage forms |
| IE59066B1 (en) | 1985-02-19 | 1993-12-15 | Key Pharma | Controlled release potassium chloride |
| US4898733A (en) * | 1985-11-04 | 1990-02-06 | International Minerals & Chemical Corp. | Layered, compression molded device for the sustained release of a beneficial agent |
| US4892742A (en) * | 1985-11-18 | 1990-01-09 | Hoffmann-La Roche Inc. | Controlled release compositions with zero order release |
| US4824675A (en) * | 1987-07-13 | 1989-04-25 | Alza Corporation | Dispenser with movable matrix comprising a plurality of tiny pills |
| AU3432689A (en) * | 1988-03-24 | 1989-10-16 | Bukh Meditec A/S | Controlled release composition |
| FI101344B1 (fi) | 1988-03-31 | 1998-06-15 | Tanabe Seiyaku Co | Menetelmä valmistaa valmiste, josta kontrolloidusti vapautuu farmaseuttisesti aktiivista ainetta |
| ES2054333T3 (es) | 1989-01-30 | 1994-08-01 | Alza Corp | Forma de dosificacion para administrar un antagonista del calcio. |
| JP2727009B2 (ja) * | 1989-03-10 | 1998-03-11 | ダイト株式会社 | 持続性製剤 |
| DK469989D0 (da) * | 1989-09-22 | 1989-09-22 | Bukh Meditec | Farmaceutisk praeparat |
| IT1237904B (it) * | 1989-12-14 | 1993-06-18 | Ubaldo Conte | Compresse a rilascio a velocita' controllata delle sostanze attive |
| US5102668A (en) * | 1990-10-05 | 1992-04-07 | Kingaform Technology, Inc. | Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH |
| US5683719A (en) | 1990-11-22 | 1997-11-04 | British Technology Group Limited | Controlled release compositions |
| GB9025372D0 (en) | 1990-11-22 | 1991-01-09 | Nat Res Dev | Pharmaceutical dosage forms |
| US5478577A (en) * | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
| US5881926A (en) | 1993-03-11 | 1999-03-16 | Taro Pharmaceutical Industries, Ltd. | Pharmaceutical compositions in semisolid form and a device for administration thereof |
| JPH071001A (ja) * | 1993-06-21 | 1995-01-06 | Nippon Steel Corp | 鏡面材用ステンレス鋼板およびその製造方法 |
| US5419917A (en) * | 1994-02-14 | 1995-05-30 | Andrx Pharmaceuticals, Inc. | Controlled release hydrogel formulation |
| DK0746310T3 (da) * | 1994-02-23 | 1999-08-02 | Bm Res As | Præparat med styret afgivelse |
| IL116674A (en) * | 1995-01-09 | 2003-05-29 | Mendell Co Inc Edward | Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof |
| US5686106A (en) * | 1995-05-17 | 1997-11-11 | The Procter & Gamble Company | Pharmaceutical dosage form for colonic delivery |
| DE69739215D1 (de) | 1996-05-20 | 2009-03-05 | Otsuka Pharma Co Ltd | Heilmittel fuer rosazla |
| US6709678B2 (en) * | 1996-08-15 | 2004-03-23 | Losan Pharma Gmbh | Easy to swallow oral medicament composition |
| GB9700624D0 (en) * | 1997-01-14 | 1997-03-05 | Danbiosyst Uk | Drug delivery composition |
| HUP0002296A3 (en) * | 1997-07-01 | 2001-11-28 | Pfizer | Sertraline salts and sustained-release dosage forms of sertraline |
| US20020054911A1 (en) * | 2000-05-11 | 2002-05-09 | Boehringer Mannheim Pharmaceutical Corporation-Sm Ithkline Beckman Corporation, Limited Partnershi | Novel oral dosage form for carvedilol |
| US6245357B1 (en) | 1998-03-06 | 2001-06-12 | Alza Corporation | Extended release dosage form |
| AU3024399A (en) | 1998-04-03 | 1999-10-25 | Bm Research A/S | Controlled release composition |
| JP4812167B2 (ja) * | 1999-02-12 | 2011-11-09 | モレキュラー インサイト ファーマスーティカルズ インコーポレイテッド | 薬物輸送用マトリックス、ならびにその作成方法および使用方法 |
| US6562375B1 (en) * | 1999-08-04 | 2003-05-13 | Yamanouchi Pharmaceuticals, Co., Ltd. | Stable pharmaceutical composition for oral use |
| US6534085B1 (en) * | 1999-09-23 | 2003-03-18 | Bioresponse L.L.C. | Phytochemicals for promoting weight loss |
| JP2003514019A (ja) | 1999-11-15 | 2003-04-15 | スミスクライン・ビーチャム・コーポレイション | カルベジロールメタンスルホン酸塩 |
| US6491949B2 (en) | 2000-01-14 | 2002-12-10 | Osmotica Corp. | Osmotic device within an osmotic device |
| US6352721B1 (en) | 2000-01-14 | 2002-03-05 | Osmotica Corp. | Combined diffusion/osmotic pumping drug delivery system |
| US20010036959A1 (en) * | 2000-04-03 | 2001-11-01 | Gabel Rolf Dieter | Carvedilol-hydrophilic solutions |
| US6488962B1 (en) * | 2000-06-20 | 2002-12-03 | Depomed, Inc. | Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms |
| WO2002065834A2 (en) | 2000-10-24 | 2002-08-29 | Smithkline Beecham Corporation | Novel formulations of carvedilol |
| IN191028B (de) | 2001-05-17 | 2003-09-13 | Sun Pharmaceutical Ind Ltd | |
| WO2003024430A1 (en) * | 2001-09-21 | 2003-03-27 | Egalet A/S | Morphine polymer release system |
| EP1929998A3 (de) * | 2001-09-21 | 2008-11-26 | Egalet A/S | Festdispersionen mit gesteuerter Freisetzung von Carvedilol |
| EP1429739A1 (de) * | 2001-09-21 | 2004-06-23 | Egalet A/S | Polymer-freigabe-system |
| CA2447984A1 (en) * | 2001-09-28 | 2003-04-03 | Mcneil-Ppc, Inc. | Dosage forms having an inner core and outer shell with different shapes |
| AU2003275953A1 (en) * | 2002-11-08 | 2004-06-07 | Egalet A/S | Controlled release carvedilol compositions |
| EP1610768B1 (de) * | 2003-03-26 | 2008-07-02 | Egalet A/S | Matrixzubereitungen für die kontrollierte darreichung von arzneistoffen |
| EP1610767B1 (de) * | 2003-03-26 | 2011-01-19 | Egalet A/S | Morphin-system mit kontrollierter freisetzung |
| WO2005007074A2 (en) | 2003-07-21 | 2005-01-27 | Bio-Dar Ltd. | Gellan gum based oral controlled release dosage forms- a novel platform technology for gastric retention |
| EA200600598A1 (ru) | 2003-09-19 | 2006-08-25 | Пенвест Фармасьютикалз Ко. | Лекарственные формы замедленного высвобождения |
| WO2005065654A2 (en) * | 2003-12-31 | 2005-07-21 | Alpharma, Inc. | Rosiglitazone formulations |
| CA2611081C (en) * | 2005-06-03 | 2016-05-31 | Egalet A/S | A drug delivery system for delivering active substances dispersed in a dispersion medium |
-
1999
- 1999-03-25 AU AU30243/99A patent/AU3024399A/en not_active Abandoned
- 1999-03-25 WO PCT/DK1999/000174 patent/WO1999051208A1/en not_active Ceased
- 1999-03-25 JP JP2000541979A patent/JP4533531B2/ja not_active Expired - Fee Related
- 1999-03-25 CA CA002327685A patent/CA2327685C/en not_active Expired - Fee Related
- 1999-03-25 DK DK99911627T patent/DK1067910T3/da active
- 1999-03-25 EP EP99911627A patent/EP1067910B1/de not_active Expired - Lifetime
- 1999-03-25 DE DE69917618T patent/DE69917618T2/de not_active Expired - Lifetime
- 1999-03-25 AT AT99911627T patent/ATE267589T1/de active
- 1999-03-25 ES ES99911627T patent/ES2221370T3/es not_active Expired - Lifetime
-
2004
- 2004-05-14 US US10/845,522 patent/US7883722B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999051208A1 (en) | 1999-10-14 |
| DE69917618T2 (de) | 2005-06-23 |
| US20050089569A1 (en) | 2005-04-28 |
| EP1067910A1 (de) | 2001-01-17 |
| JP4533531B2 (ja) | 2010-09-01 |
| CA2327685A1 (en) | 1999-10-14 |
| CA2327685C (en) | 2008-11-18 |
| DK1067910T3 (da) | 2004-10-04 |
| ES2221370T3 (es) | 2004-12-16 |
| AU3024399A (en) | 1999-10-25 |
| US7883722B2 (en) | 2011-02-08 |
| JP2002510616A (ja) | 2002-04-09 |
| ATE267589T1 (de) | 2004-06-15 |
| EP1067910B1 (de) | 2004-05-26 |
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