AU2016366398A1 - Bicyclic inhibitors of PAD4 - Google Patents

Bicyclic inhibitors of PAD4 Download PDF

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Publication number
AU2016366398A1
AU2016366398A1 AU2016366398A AU2016366398A AU2016366398A1 AU 2016366398 A1 AU2016366398 A1 AU 2016366398A1 AU 2016366398 A AU2016366398 A AU 2016366398A AU 2016366398 A AU2016366398 A AU 2016366398A AU 2016366398 A1 AU2016366398 A1 AU 2016366398A1
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Australia
Prior art keywords
methyl
pyrrolo
mmol
cyclopropylmethyl
pyridin
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Abandoned
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AU2016366398A
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English (en)
Inventor
Edward BEAUMONT
Lee BOWLES
Steve BROMBRIDGE
Sophie COOPER
Rajesh Devraj
Elise GADOULEAU
Laura Gleave
Philip KERRY
Adrian KOTEY
Thomas Krulle
Gnanasambandam Kumaravel
Cristina Lecci
Pui LOKE
Mirco Meniconi
Nat Monck
Carl NORTH
Jordan PALFREY
Michael F. Parker
Shelley PARROTT
Mark Ridgill
Heather Tye
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Padlock Therapeutics Inc
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Padlock Therapeutics Inc
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Publication of AU2016366398A1 publication Critical patent/AU2016366398A1/en
Abandoned legal-status Critical Current

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    • C07—ORGANIC CHEMISTRY
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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