AU2014228990B2 - Rapid disperse dosage form containing levetiracetam - Google Patents

Rapid disperse dosage form containing levetiracetam Download PDF

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Publication number
AU2014228990B2
AU2014228990B2 AU2014228990A AU2014228990A AU2014228990B2 AU 2014228990 B2 AU2014228990 B2 AU 2014228990B2 AU 2014228990 A AU2014228990 A AU 2014228990A AU 2014228990 A AU2014228990 A AU 2014228990A AU 2014228990 B2 AU2014228990 B2 AU 2014228990B2
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AU
Australia
Prior art keywords
dosage form
matrix
lev
less
bound
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AU2014228990A
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English (en)
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AU2014228990A1 (en
Inventor
Norman COYLE
Jules Jacob
Nemichand B. Jain
Donald C. Monkhouse
Henry L. Surprenant
Thomas G. West
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Aprecia Pharmaceuticals LLC
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Aprecia Pharmaceuticals LLC
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Publication of AU2014228990A1 publication Critical patent/AU2014228990A1/en
Application granted granted Critical
Publication of AU2014228990B2 publication Critical patent/AU2014228990B2/en
Priority to AU2017202752A priority Critical patent/AU2017202752B2/en
Assigned to Aprecia Pharmaceuticals LLC reassignment Aprecia Pharmaceuticals LLC Request for Assignment Assignors: APRECIA PHARMACEUTICALS COMPANY
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2014228990A 2013-03-15 2014-03-14 Rapid disperse dosage form containing levetiracetam Active AU2014228990B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2017202752A AU2017202752B2 (en) 2013-03-15 2017-04-26 Rapid disperse dosage form containing levetiracetam

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361791444P 2013-03-15 2013-03-15
US61/791,444 2013-03-15
PCT/US2014/028954 WO2014144512A1 (en) 2013-03-15 2014-03-14 Rapid disperse dosage form containing levetiracetam

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2017202752A Division AU2017202752B2 (en) 2013-03-15 2017-04-26 Rapid disperse dosage form containing levetiracetam

Publications (2)

Publication Number Publication Date
AU2014228990A1 AU2014228990A1 (en) 2015-10-08
AU2014228990B2 true AU2014228990B2 (en) 2017-02-02

Family

ID=51537722

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2014228990A Active AU2014228990B2 (en) 2013-03-15 2014-03-14 Rapid disperse dosage form containing levetiracetam
AU2017202752A Active AU2017202752B2 (en) 2013-03-15 2017-04-26 Rapid disperse dosage form containing levetiracetam

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2017202752A Active AU2017202752B2 (en) 2013-03-15 2017-04-26 Rapid disperse dosage form containing levetiracetam

Country Status (10)

Country Link
US (6) US9339489B2 (enExample)
EP (2) EP3431141B1 (enExample)
JP (3) JP6170234B2 (enExample)
CN (2) CN109908355B (enExample)
AU (2) AU2014228990B2 (enExample)
CA (1) CA2906029C (enExample)
ES (2) ES2908292T3 (enExample)
HK (1) HK1216513A1 (enExample)
MX (1) MX365513B (enExample)
WO (1) WO2014144512A1 (enExample)

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AU2021296908A1 (en) 2020-06-26 2023-02-16 Aprecia Pharmaceuticals LLC Rapidly-orodispersible tablets having an interior cavity
CN111840243B (zh) * 2020-07-30 2021-11-30 中国人民解放军军事科学院军事医学研究院 一种左乙拉西坦3d打印制剂及其制备方法
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