AU2013291990B2 - Filtration of cell culture supernatants - Google Patents

Filtration of cell culture supernatants Download PDF

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Publication number
AU2013291990B2
AU2013291990B2 AU2013291990A AU2013291990A AU2013291990B2 AU 2013291990 B2 AU2013291990 B2 AU 2013291990B2 AU 2013291990 A AU2013291990 A AU 2013291990A AU 2013291990 A AU2013291990 A AU 2013291990A AU 2013291990 B2 AU2013291990 B2 AU 2013291990B2
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AU
Australia
Prior art keywords
filter
cells
pore size
liquid
bar
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AU2013291990A
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English (en)
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AU2013291990A1 (en
Inventor
Thomas Grosse
Holger Niederkruger
Andreas Schaaf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eleva GmbH
Original Assignee
Greenovation Biotech GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Greenovation Biotech GmbH filed Critical Greenovation Biotech GmbH
Publication of AU2013291990A1 publication Critical patent/AU2013291990A1/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02Separating microorganisms from their culture media
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02Separating microorganisms from the culture medium; Concentration of biomass
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10Separation or concentration of fermentation products
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04Plant cells or tissues

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Sustainable Development (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Water Supply & Treatment (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
AU2013291990A 2012-07-20 2013-07-19 Filtration of cell culture supernatants Active AU2013291990B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12177277.6A EP2687592A1 (de) 2012-07-20 2012-07-20 Filtration von Zellkulturüberständen
EP12177277.6 2012-07-20
PCT/EP2013/065264 WO2014013045A1 (de) 2012-07-20 2013-07-19 Filtration von zellkulturüberständen

Publications (2)

Publication Number Publication Date
AU2013291990A1 AU2013291990A1 (en) 2015-01-29
AU2013291990B2 true AU2013291990B2 (en) 2019-01-03

Family

ID=48803559

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013291990A Active AU2013291990B2 (en) 2012-07-20 2013-07-19 Filtration of cell culture supernatants

Country Status (20)

Country Link
US (1) US10081789B2 (enExample)
EP (2) EP2687592A1 (enExample)
JP (2) JP6693743B2 (enExample)
KR (1) KR102087258B1 (enExample)
CN (1) CN104769102B (enExample)
AU (1) AU2013291990B2 (enExample)
BR (1) BR112015001120B1 (enExample)
CA (1) CA2882100C (enExample)
DK (1) DK2875123T3 (enExample)
ES (1) ES2717278T3 (enExample)
HR (1) HRP20190464T1 (enExample)
IL (1) IL236447B (enExample)
IN (1) IN2014DN11263A (enExample)
LT (1) LT2875123T (enExample)
MX (1) MX366586B (enExample)
PL (1) PL2875123T3 (enExample)
PT (1) PT2875123T (enExample)
SI (1) SI2875123T1 (enExample)
TR (1) TR201903915T4 (enExample)
WO (1) WO2014013045A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3271453T3 (da) 2015-03-17 2021-11-15 eleva GmbH Glycosylerede lysosomale proteiner, fremgangsmåde til fremstilling og anvendelser
EP3283092A1 (en) * 2015-04-14 2018-02-21 Vytrus Biotech, S.L. Cell-free plant cell culture suspension supernatant with re-youth activity and/or wound healing activity over skin cells
BE1025089B1 (fr) * 2017-03-30 2018-10-29 Univercells Sa Clarification de culture cellulaire
WO2025147484A1 (en) * 2024-01-04 2025-07-10 Wainamics, Inc. Microfluidic biospecimen cartridge

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1571504A (en) * 1976-01-29 1980-07-16 English Clays Lovering Pochin Separation of solids and liquids
US5254096A (en) * 1992-09-23 1993-10-19 Becton, Dickinson And Company Syringe pump with graphical display or error conditions
JP2000279772A (ja) 1999-03-30 2000-10-10 Ngk Insulators Ltd セラミック膜フィルターによるろ過方法
DE19937187A1 (de) * 1999-08-06 2001-03-01 Qiagen Gmbh Automatisierte Proteinreinigung im Multiwellformat durch Vakuumfiltration
US6692702B1 (en) * 2000-07-07 2004-02-17 Coulter International Corp. Apparatus for biological sample preparation and analysis
WO2005108596A1 (en) * 2004-05-07 2005-11-17 Friedrich-Alexander-Universität Erlangen-Nürnberg Method for producing cyclic peptides from in vitro plant cell cultures
EP2054498A1 (de) * 2006-08-15 2009-05-06 Basf Se Verfahren zur isolierung von proteinen aus produktionszellen
US9932620B2 (en) * 2012-05-21 2018-04-03 Celsis Ltd. Methods, devices, and systems of detecting microorganisms
JP6453592B2 (ja) * 2013-09-25 2019-01-16 アークレイ株式会社 血液検体の処理方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ANNETTE B�TTNER-MAINIK, JULIANA PARSONS, HANNA J�R�ME, ANDREA HARTMANN, STEPHANIE LAMER, ANDREAS SCHAAF, ANDREAS SCHLOSSER, PETER : "Production of biologically active recombinant human factor H in Physcomitrella", PLANT BIOTECHNOLOGY JOURNAL, vol. 9, no. 3, 1 April 2011 (2011-04-01), pages 373 - 383, XP002688821, DOI: 10.1111/J.1467-7652.2010.00552.X *
SELLSTEDT A: "Occurrence and activity of hydrogenase in symbiotic frankia from field collected alnus-incana", Physiologia Plantarum, 1989, Vol 75, p304-308. *

Also Published As

Publication number Publication date
WO2014013045A1 (de) 2014-01-23
CA2882100C (en) 2021-07-06
PL2875123T3 (pl) 2019-06-28
JP2015522287A (ja) 2015-08-06
LT2875123T (lt) 2019-04-10
PT2875123T (pt) 2019-04-22
EP2687592A1 (de) 2014-01-22
BR112015001120B1 (pt) 2022-03-22
KR102087258B1 (ko) 2020-03-11
ES2717278T3 (es) 2019-06-20
AU2013291990A1 (en) 2015-01-29
IL236447A0 (en) 2015-02-26
MX366586B (es) 2019-07-15
US10081789B2 (en) 2018-09-25
KR20150031292A (ko) 2015-03-23
HRP20190464T1 (hr) 2019-05-03
CA2882100A1 (en) 2014-01-23
IN2014DN11263A (enExample) 2015-10-09
BR112015001120A2 (pt) 2017-06-27
CN104769102B (zh) 2020-11-03
SI2875123T1 (sl) 2019-05-31
IL236447B (en) 2019-05-30
JP6693743B2 (ja) 2020-05-13
US20150147811A1 (en) 2015-05-28
EP2875123A1 (de) 2015-05-27
EP2875123B1 (de) 2018-12-26
DK2875123T3 (en) 2019-04-08
MX2015000680A (es) 2015-04-10
JP2018157827A (ja) 2018-10-11
TR201903915T4 (tr) 2019-04-22
CN104769102A (zh) 2015-07-08

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