BR112015001120A2 - filtração de sobrenadantes de cultura de células - Google Patents
filtração de sobrenadantes de cultura de célulasInfo
- Publication number
- BR112015001120A2 BR112015001120A2 BR112015001120A BR112015001120A BR112015001120A2 BR 112015001120 A2 BR112015001120 A2 BR 112015001120A2 BR 112015001120 A BR112015001120 A BR 112015001120A BR 112015001120 A BR112015001120 A BR 112015001120A BR 112015001120 A2 BR112015001120 A2 BR 112015001120A2
- Authority
- BR
- Brazil
- Prior art keywords
- filter
- mixture
- filtration
- cell culture
- culture supernatants
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/02—Separating microorganisms from their culture media
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/10—Separation or concentration of fermentation products
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/04—Plant cells or tissues
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Sustainable Development (AREA)
- Botany (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Water Supply & Treatment (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
Abstract
resumo da patente de invenção para "filtração de sobrenadantes de cultura de células". a invenção se refere a um processo para a separação de um sobrenadante líquido de células compreendendo as etapas de: fornecimento de uma mistura das células com um líquido, carregamento de um primeiro compartimento de filtro com a mistura, em que no compartimento de filtro é fornecido um filtro com um tamanho de poro entre 4 µm e 50 µm sobre uma superfície de base plana perfurada em forma de peneira e as paredes do compartimento de filtro são conectadas de forma a vedar com a superfície de base plana, que é perfurada em forma de peneira, aplicação de uma pressão diferencial de pelo menos 0,5 bar (50000 pa) sobre a mistura, como um resultado do qual a porção líquida da mistura é forçada através do filtro e um bolo de filtração contendo células permanece no compartimento de filtro, e remoção do fluido filtrado.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12177277.6A EP2687592A1 (de) | 2012-07-20 | 2012-07-20 | Filtration von Zellkulturüberständen |
| EP12177277.6 | 2012-07-20 | ||
| PCT/EP2013/065264 WO2014013045A1 (de) | 2012-07-20 | 2013-07-19 | Filtration von zellkulturüberständen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112015001120A2 true BR112015001120A2 (pt) | 2017-06-27 |
| BR112015001120B1 BR112015001120B1 (pt) | 2022-03-22 |
Family
ID=48803559
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015001120-9A BR112015001120B1 (pt) | 2012-07-20 | 2013-07-19 | Filtração de sobrenadantes de cultura de células |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US10081789B2 (pt) |
| EP (2) | EP2687592A1 (pt) |
| JP (2) | JP6693743B2 (pt) |
| KR (1) | KR102087258B1 (pt) |
| CN (1) | CN104769102B (pt) |
| AU (1) | AU2013291990B2 (pt) |
| BR (1) | BR112015001120B1 (pt) |
| CA (1) | CA2882100C (pt) |
| DK (1) | DK2875123T3 (pt) |
| ES (1) | ES2717278T3 (pt) |
| HR (1) | HRP20190464T1 (pt) |
| IL (1) | IL236447B (pt) |
| IN (1) | IN2014DN11263A (pt) |
| LT (1) | LT2875123T (pt) |
| MX (1) | MX366586B (pt) |
| PL (1) | PL2875123T3 (pt) |
| PT (1) | PT2875123T (pt) |
| SI (1) | SI2875123T1 (pt) |
| TR (1) | TR201903915T4 (pt) |
| WO (1) | WO2014013045A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3271453T (lt) | 2015-03-17 | 2021-11-10 | eleva GmbH | Glikozilinti lizosominiai baltymai, jų gamybos būdas ir panaudojimas |
| EP3283092A1 (en) * | 2015-04-14 | 2018-02-21 | Vytrus Biotech, S.L. | Cell-free plant cell culture suspension supernatant with re-youth activity and/or wound healing activity over skin cells |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1571504A (en) * | 1976-01-29 | 1980-07-16 | English Clays Lovering Pochin | Separation of solids and liquids |
| US5254096A (en) * | 1992-09-23 | 1993-10-19 | Becton, Dickinson And Company | Syringe pump with graphical display or error conditions |
| JP2000279772A (ja) * | 1999-03-30 | 2000-10-10 | Ngk Insulators Ltd | セラミック膜フィルターによるろ過方法 |
| DE19937187A1 (de) * | 1999-08-06 | 2001-03-01 | Qiagen Gmbh | Automatisierte Proteinreinigung im Multiwellformat durch Vakuumfiltration |
| US6692702B1 (en) * | 2000-07-07 | 2004-02-17 | Coulter International Corp. | Apparatus for biological sample preparation and analysis |
| EP1747278A1 (en) * | 2004-05-07 | 2007-01-31 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Method for producing cyclic peptides from in vitro plant cell cultures |
| CN101522884B (zh) * | 2006-08-15 | 2013-08-21 | 巴斯夫欧洲公司 | 从生产细胞中分离蛋白质的方法 |
| US9932620B2 (en) * | 2012-05-21 | 2018-04-03 | Celsis Ltd. | Methods, devices, and systems of detecting microorganisms |
| JP6453592B2 (ja) * | 2013-09-25 | 2019-01-16 | アークレイ株式会社 | 血液検体の処理方法 |
-
2012
- 2012-07-20 EP EP12177277.6A patent/EP2687592A1/de not_active Withdrawn
-
2013
- 2013-07-19 SI SI201331390T patent/SI2875123T1/sl unknown
- 2013-07-19 KR KR1020157001096A patent/KR102087258B1/ko active IP Right Grant
- 2013-07-19 PT PT13739224T patent/PT2875123T/pt unknown
- 2013-07-19 LT LTEP13739224.7T patent/LT2875123T/lt unknown
- 2013-07-19 EP EP13739224.7A patent/EP2875123B1/de active Active
- 2013-07-19 AU AU2013291990A patent/AU2013291990B2/en active Active
- 2013-07-19 JP JP2015522110A patent/JP6693743B2/ja active Active
- 2013-07-19 BR BR112015001120-9A patent/BR112015001120B1/pt active IP Right Grant
- 2013-07-19 TR TR2019/03915T patent/TR201903915T4/tr unknown
- 2013-07-19 CA CA2882100A patent/CA2882100C/en active Active
- 2013-07-19 DK DK13739224.7T patent/DK2875123T3/en active
- 2013-07-19 IN IN11263DEN2014 patent/IN2014DN11263A/en unknown
- 2013-07-19 PL PL13739224T patent/PL2875123T3/pl unknown
- 2013-07-19 MX MX2015000680A patent/MX366586B/es active IP Right Grant
- 2013-07-19 ES ES13739224T patent/ES2717278T3/es active Active
- 2013-07-19 WO PCT/EP2013/065264 patent/WO2014013045A1/de active Application Filing
- 2013-07-19 CN CN201380038651.3A patent/CN104769102B/zh active Active
- 2013-07-19 US US14/414,261 patent/US10081789B2/en active Active
-
2014
- 2014-12-25 IL IL236447A patent/IL236447B/en active IP Right Grant
-
2018
- 2018-06-13 JP JP2018112570A patent/JP2018157827A/ja active Pending
-
2019
- 2019-03-08 HR HRP20190464TT patent/HRP20190464T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL236447B (en) | 2019-05-30 |
| US10081789B2 (en) | 2018-09-25 |
| EP2875123B1 (de) | 2018-12-26 |
| JP2015522287A (ja) | 2015-08-06 |
| US20150147811A1 (en) | 2015-05-28 |
| CA2882100C (en) | 2021-07-06 |
| IN2014DN11263A (pt) | 2015-10-09 |
| ES2717278T3 (es) | 2019-06-20 |
| PL2875123T3 (pl) | 2019-06-28 |
| DK2875123T3 (en) | 2019-04-08 |
| EP2875123A1 (de) | 2015-05-27 |
| IL236447A0 (en) | 2015-02-26 |
| JP2018157827A (ja) | 2018-10-11 |
| SI2875123T1 (sl) | 2019-05-31 |
| CN104769102B (zh) | 2020-11-03 |
| PT2875123T (pt) | 2019-04-22 |
| CN104769102A (zh) | 2015-07-08 |
| LT2875123T (lt) | 2019-04-10 |
| KR20150031292A (ko) | 2015-03-23 |
| MX366586B (es) | 2019-07-15 |
| AU2013291990A1 (en) | 2015-01-29 |
| BR112015001120B1 (pt) | 2022-03-22 |
| HRP20190464T1 (hr) | 2019-05-03 |
| TR201903915T4 (tr) | 2019-04-22 |
| KR102087258B1 (ko) | 2020-03-11 |
| EP2687592A1 (de) | 2014-01-22 |
| CA2882100A1 (en) | 2014-01-23 |
| AU2013291990B2 (en) | 2019-01-03 |
| JP6693743B2 (ja) | 2020-05-13 |
| WO2014013045A1 (de) | 2014-01-23 |
| MX2015000680A (es) | 2015-04-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA. |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B25D | Requested change of name of applicant approved |
Owner name: ELEVA GMBH (DE) |
|
| B25G | Requested change of headquarter approved |
Owner name: ELEVA GMBH (DE) |
|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B25K | Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: republication |
Owner name: ELEVA GMBH (DE) Free format text: RETIFICACAO DO DESPACHO (25.7) ? ALTERACAO DE SEDE PUBLICADO NA RPI NO 2637, DE 20/07/2021, QUANTO AO ITEM (71) ? DEPOSITANTE NO PARECER.ONDE SE LE: GREENOVATION BIOTECH GMBHLEIA-SE: ELEVA GMBH |
|
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/07/2013, OBSERVADAS AS CONDICOES LEGAIS. |