CN113088487A - 一种间充质干细胞成脂转化抑制剂 - Google Patents
一种间充质干细胞成脂转化抑制剂 Download PDFInfo
- Publication number
- CN113088487A CN113088487A CN202110393609.XA CN202110393609A CN113088487A CN 113088487 A CN113088487 A CN 113088487A CN 202110393609 A CN202110393609 A CN 202110393609A CN 113088487 A CN113088487 A CN 113088487A
- Authority
- CN
- China
- Prior art keywords
- carrageenan
- transferring
- precipitate
- ethanol
- mesenchymal stem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/90—Polysaccharides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Developmental Biology & Embryology (AREA)
- Molecular Biology (AREA)
- Sustainable Development (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Polymers & Plastics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Description
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110393609.XA CN113088487B (zh) | 2020-04-30 | 2020-04-30 | 一种间充质干细胞成脂转化抑制剂 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010361704.7A CN111454899B (zh) | 2020-04-30 | 2020-04-30 | 角叉菜多糖在抑制间充质干细胞成脂转化中的用途 |
CN202110393609.XA CN113088487B (zh) | 2020-04-30 | 2020-04-30 | 一种间充质干细胞成脂转化抑制剂 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202010361704.7A Division CN111454899B (zh) | 2020-04-30 | 2020-04-30 | 角叉菜多糖在抑制间充质干细胞成脂转化中的用途 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN113088487A true CN113088487A (zh) | 2021-07-09 |
CN113088487B CN113088487B (zh) | 2022-12-06 |
Family
ID=71676495
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202010361704.7A Active CN111454899B (zh) | 2020-04-30 | 2020-04-30 | 角叉菜多糖在抑制间充质干细胞成脂转化中的用途 |
CN202110393609.XA Active CN113088487B (zh) | 2020-04-30 | 2020-04-30 | 一种间充质干细胞成脂转化抑制剂 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202010361704.7A Active CN111454899B (zh) | 2020-04-30 | 2020-04-30 | 角叉菜多糖在抑制间充质干细胞成脂转化中的用途 |
Country Status (1)
Country | Link |
---|---|
CN (2) | CN111454899B (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112210529A (zh) * | 2020-10-15 | 2021-01-12 | 青岛嘉智生物技术有限公司 | 一种抑制猪前体脂肪细胞分化的提取物 |
CN113899709A (zh) * | 2021-09-10 | 2022-01-07 | 中国水产科学研究院珠江水产研究所 | 一种定量检测鱼类肠系膜脂肪沉积量的方法以及应用 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113563490B (zh) * | 2021-08-26 | 2022-04-15 | 广东丸美生物技术股份有限公司 | 一种角叉菜多糖提取物及其制备方法与应用 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1468261A (zh) * | 2000-08-03 | 2004-01-14 | �ն�����ʿ��˾ | 制造化学改性或酶改性多糖的方法及由其制得的产品 |
CN1608082A (zh) * | 2001-12-28 | 2005-04-20 | Cp凱尔科有限公司 | 一种由双组分海藻制造和分级胶凝和非胶凝角叉菜聚糖的方法 |
ES2351474T3 (es) * | 2006-08-04 | 2011-02-07 | L'oreal | Composición cosmética que comprende al menos un polisacárido de tipo carragenano lambda en asociación con al menos un agente tensioactivo no iónico de tipo alquilpoliglucósico, procedimiento de tratamiento cosmético de las fibras queratínicas y utilización de la composición. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ511506A (en) * | 1998-10-28 | 2004-02-27 | Sankyo Co | Remedies for bone metabolic errors comprising OCIF |
CN102499458B (zh) * | 2011-10-28 | 2013-08-21 | 浙江中烟工业有限责任公司 | 海洋藻类多糖及其制备方法和在卷烟中的应用 |
CN104892785B (zh) * | 2015-05-29 | 2017-07-07 | 湖南尔康制药股份有限公司 | 一种海藻多糖的提取方法 |
-
2020
- 2020-04-30 CN CN202010361704.7A patent/CN111454899B/zh active Active
- 2020-04-30 CN CN202110393609.XA patent/CN113088487B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1468261A (zh) * | 2000-08-03 | 2004-01-14 | �ն�����ʿ��˾ | 制造化学改性或酶改性多糖的方法及由其制得的产品 |
CN1608082A (zh) * | 2001-12-28 | 2005-04-20 | Cp凱尔科有限公司 | 一种由双组分海藻制造和分级胶凝和非胶凝角叉菜聚糖的方法 |
ES2351474T3 (es) * | 2006-08-04 | 2011-02-07 | L'oreal | Composición cosmética que comprende al menos un polisacárido de tipo carragenano lambda en asociación con al menos un agente tensioactivo no iónico de tipo alquilpoliglucósico, procedimiento de tratamiento cosmético de las fibras queratínicas y utilización de la composición. |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112210529A (zh) * | 2020-10-15 | 2021-01-12 | 青岛嘉智生物技术有限公司 | 一种抑制猪前体脂肪细胞分化的提取物 |
CN112210529B (zh) * | 2020-10-15 | 2022-06-07 | 青岛嘉智生物技术有限公司 | 一种抑制猪前体脂肪细胞分化的提取物 |
CN113899709A (zh) * | 2021-09-10 | 2022-01-07 | 中国水产科学研究院珠江水产研究所 | 一种定量检测鱼类肠系膜脂肪沉积量的方法以及应用 |
Also Published As
Publication number | Publication date |
---|---|
CN113088487B (zh) | 2022-12-06 |
CN111454899B (zh) | 2021-04-20 |
CN111454899A (zh) | 2020-07-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN113088487B (zh) | 一种间充质干细胞成脂转化抑制剂 | |
CN111658775B (zh) | 长链非编码rna在干细胞成骨分化和成脂分化中的作用 | |
CN112574946B (zh) | 一种原代分离培养土狗多个组织来源的成纤维细胞及其永生化的构建方法 | |
CN106591224B (zh) | 高纯度鸡前体肌内脂肪细胞的分离纯化及构建其与肌卫星细胞共培养体系的方法 | |
CN101705209B (zh) | 一种从棕色脂肪分离心脏干细胞及其成心肌细胞分化的方法 | |
CN114854676A (zh) | 一种草鱼骨骼肌成肌细胞系的构建方法及其应用 | |
CN111534487B (zh) | 一种促进间充质干细胞成骨分化的促进剂 | |
CN111004776A (zh) | 一种马骨骼肌卫星细胞的分离培养方法 | |
CN115478050B (zh) | 一种提高干细胞体外扩增能力的方法 | |
CN111849878A (zh) | 一种提高间充质干细胞成骨能力的方法 | |
CN117402819B (zh) | 骨髓间充质干细胞的外泌体、体外培养方法以及应用 | |
CN111718898B (zh) | 提高滑膜间充质干细胞逆境耐受性的方法及其试剂 | |
WO2022146374A2 (en) | Use of plant-derived exosomes for inducing differentiation of stem cell sources into cartilage and bone cells | |
CN114934089B (zh) | 一种用于瘦肉猪育种的生物制剂 | |
CN117736975B (zh) | 一种子宫内膜干细胞的分离提取和培养方法 | |
KR100397220B1 (ko) | 녹용으로부터 추출된 골형성 촉진 물질 및 그의 추출방법 | |
CN116590225B (zh) | 磷脂酰胆碱在制备促进猪FAPs细胞分化聚脂制剂中的应用 | |
CN114262688B (zh) | 一种从非神经细胞转化制备保留年龄特征的抑制性中间神经元的方法 | |
CN113754790B (zh) | 一种促进细胞生长的生物制剂 | |
RU2430969C2 (ru) | Высокополимерная рнк из пекарских дрожжей, свободная от примесных ассоциатов рнк с белками и полисахаридами | |
CN114164235A (zh) | Sdccag3过表达载体在制备调控骨组织成脂药物中的应用 | |
CN118599767A (zh) | 一种无血清培养的脐带间充质干细胞来源的细胞外囊泡及其制备和应用 | |
CN1597936A (zh) | 培养和增殖脂肪组织来源的干细胞的方法 | |
CN115058385A (zh) | 一种高血压小鼠心肌成纤维细胞分离培养方法及其应用 | |
CN115948329A (zh) | 一种心肌细胞及心肌炎症细胞外泌体提取方法及其应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20221116 Address after: 264203 12th floor, office building of Weihai Zhengsheng Biotechnology Co., Ltd., north of Huanghe street and east of Guangtai airport, Zhangcun Town, Huancui District, Weihai City, Shandong Province Applicant after: Weihai Jiansheng Biotechnology Co.,Ltd. Address before: Room 202, building 15, Max business Hongwan, 17 Guangbo Road, high tech Zone, Chengyang District, Qingdao City, Shandong Province 266109 Applicant before: Qingdao Situo Xinyuan Cell Medicine Co.,Ltd. |
|
TA01 | Transfer of patent application right | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: An inhibitor of mesenchymal stem cell lipogenic transformation Effective date of registration: 20230425 Granted publication date: 20221206 Pledgee: Industrial and Commercial Bank of China Limited Weihai Branch Pledgor: Weihai Jiansheng Biotechnology Co.,Ltd. Registration number: Y2023980039089 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right |