AU2013286093B2 - Complexes of cytomegalovirus proteins - Google Patents
Complexes of cytomegalovirus proteins Download PDFInfo
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- AU2013286093B2 AU2013286093B2 AU2013286093A AU2013286093A AU2013286093B2 AU 2013286093 B2 AU2013286093 B2 AU 2013286093B2 AU 2013286093 A AU2013286093 A AU 2013286093A AU 2013286093 A AU2013286093 A AU 2013286093A AU 2013286093 B2 AU2013286093 B2 AU 2013286093B2
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- 108700010903 cytomegalovirus proteins Proteins 0.000 title claims 2
- 241000701024 Human betaherpesvirus 5 Species 0.000 claims abstract description 296
- 238000000034 method Methods 0.000 claims abstract description 89
- 239000000203 mixture Substances 0.000 claims abstract description 86
- 230000008569 process Effects 0.000 claims abstract description 53
- 102000003886 Glycoproteins Human genes 0.000 claims abstract description 40
- 108090000288 Glycoproteins Proteins 0.000 claims abstract description 40
- 230000002163 immunogen Effects 0.000 claims abstract description 29
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- 108020004707 nucleic acids Proteins 0.000 claims description 105
- 150000007523 nucleic acids Chemical class 0.000 claims description 105
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- 208000015181 infectious disease Diseases 0.000 claims description 13
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| WO2017044895A2 (en) | 2015-09-10 | 2017-03-16 | City Of Hope | MVA-gH/gL-PC VACCINE DERIVED ANTIBODIES NEUTRALIZING HUMAN CYTOMEGALOVIRUS INFECTIVITY AND METHODS THEREOF |
| EP3364981A4 (en) | 2015-10-22 | 2019-08-07 | ModernaTX, Inc. | VACCINE AGAINST THE HUMAN CYTOMEGALOVIRUS |
| JP2019511255A (ja) | 2016-01-11 | 2019-04-25 | バーンダリ，インク． | マイクロニードル組成物およびそれを使用する方法 |
| US10611800B2 (en) | 2016-03-11 | 2020-04-07 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| CA3041307A1 (en) | 2016-10-21 | 2018-04-26 | Giuseppe Ciaramella | Human cytomegalovirus vaccine |
| JP2020515522A (ja) * | 2017-01-27 | 2020-05-28 | ザ ヘンリー エム． ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド | 免疫応答を誘導するヘルペスウイルスエンベロープタンパク質の組み合わせのワクチン組成物 |
| EP4559869A3 (en) | 2017-04-04 | 2025-08-20 | University of Washington | Self-assembling protein nanostructures displaying paramyxovirus and/or pneumovirus f proteins and their use |
| MX2019012525A (es) | 2017-04-19 | 2019-12-05 | Glaxosmithkline Biologicals Sa | Proteinas de citomegalovirus modificadas y complejos estabilizados. |
| US11174322B2 (en) * | 2017-07-24 | 2021-11-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antibodies and peptides to treat HCMV related diseases |
| SG11202000019RA (en) * | 2017-07-28 | 2020-02-27 | Janssen Vaccines & Prevention Bv | Methods and compositions for heterologous reprna immunizations |
| EP3681534A1 (en) * | 2017-09-13 | 2020-07-22 | Sanofi Pasteur | Human cytomegalovirus immunogenic composition |
| CA3095216A1 (en) * | 2018-02-28 | 2019-09-06 | University Of Washington | Self-asssembling nanostructure vaccines |
| JP7575096B2 (ja) | 2018-05-04 | 2024-10-29 | スパイバイオテック・リミテッド | ワクチン組成物 |
| CA3116175A1 (en) * | 2018-10-17 | 2020-04-23 | Glaxosmithkline Biologicals Sa | Modified cytomegalovirus proteins and stabilized complexes |
| KR102609106B1 (ko) | 2018-12-10 | 2023-12-05 | 케이엠 바이올로직스 가부시키가이샤 | 사이토메갈로바이러스의 선천성 감염을 예방 또는 치료하기 위한 백신 |
| US11629172B2 (en) * | 2018-12-21 | 2023-04-18 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| WO2021014385A1 (en) | 2019-07-24 | 2021-01-28 | Glaxosmithkline Biologicals Sa | Modified human cytomegalovirus proteins |
| JP7271794B2 (ja) * | 2020-06-09 | 2023-05-11 | Ｋｍバイオロジクス株式会社 | サイトメガロウイルスのｇＢとペンタマーとの融合タンパク質及び該融合タンパク質を含むワクチン |
| TWI810589B (zh) | 2020-06-21 | 2023-08-01 | 美商輝瑞股份有限公司 | 人巨細胞病毒糖蛋白Ｂ（ｇＢ）多肽 |
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| WO2023144665A1 (en) | 2022-01-28 | 2023-08-03 | Glaxosmithkline Biologicals Sa | Modified human cytomegalovirus proteins |
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| JP2017192399A (ja) | 2017-10-26 |
| GB2513768A (en) | 2014-11-05 |
| WO2014005959A1 (en) | 2014-01-09 |
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