AU2007323042B2 - New process for the preparation of 2-imino-thiazolidin-4-one derivatives - Google Patents

New process for the preparation of 2-imino-thiazolidin-4-one derivatives Download PDF

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Publication number
AU2007323042B2
AU2007323042B2 AU2007323042A AU2007323042A AU2007323042B2 AU 2007323042 B2 AU2007323042 B2 AU 2007323042B2 AU 2007323042 A AU2007323042 A AU 2007323042A AU 2007323042 A AU2007323042 A AU 2007323042A AU 2007323042 B2 AU2007323042 B2 AU 2007323042B2
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AU
Australia
Prior art keywords
thiazolidin
hydroxy
benz
ylidene
phenyl
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AU2007323042A
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English (en)
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AU2007323042A1 (en
Inventor
Stefan Abele
Martin Bolli
Gunther Schmidt
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Laboratoires Juvise Pharmaceuticals SAS
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Laboratoires Juvise Pharmaceuticals SAS
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54—Nitrogen and either oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2007323042A 2006-11-23 2007-11-22 New process for the preparation of 2-imino-thiazolidin-4-one derivatives Active AU2007323042B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IBPCT/IB2006/054409 2006-11-23
IB2006054409 2006-11-23
PCT/IB2007/054752 WO2008062376A2 (en) 2006-11-23 2007-11-22 New process for the preparation of 2-imino-thiazolidin-4-one derivatives

Publications (2)

Publication Number Publication Date
AU2007323042A1 AU2007323042A1 (en) 2008-05-29
AU2007323042B2 true AU2007323042B2 (en) 2012-12-20

Family

ID=39316391

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007323042A Active AU2007323042B2 (en) 2006-11-23 2007-11-22 New process for the preparation of 2-imino-thiazolidin-4-one derivatives

Country Status (13)

Country Link
US (1) US8263780B2 (enExample)
EP (2) EP2094676B1 (enExample)
JP (1) JP4669564B2 (enExample)
KR (1) KR101255879B1 (enExample)
CN (2) CN103087004A (enExample)
AU (1) AU2007323042B2 (enExample)
CA (1) CA2669069C (enExample)
DK (2) DK2489662T3 (enExample)
ES (2) ES2410793T3 (enExample)
IL (1) IL198847A (enExample)
MX (1) MX2009005048A (enExample)
TW (1) TWI460166B (enExample)
WO (1) WO2008062376A2 (enExample)

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USRE43833E1 (en) 2003-11-21 2012-11-27 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
AU2004295047B2 (en) 2003-11-21 2011-03-10 Laboratoires Juvise Pharmaceuticals 5-(benz- (Z) -ylidene) -thiazolidin-4-one derivatives as immunosuppressant agents
US8912340B2 (en) 2006-11-23 2014-12-16 Actelion Pharmaceuticals Ltd. Process for the preparation of 2-imino-thiazolidin-4-one derivatives
DK2278960T4 (da) * 2008-03-17 2020-01-27 Actelion Pharmaceuticals Ltd Dosisregimen til en selektiv sip1 receptoragonist
GB0819182D0 (en) 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms
HRP20200883T1 (hr) 2012-08-17 2020-09-04 Actelion Pharmaceuticals Ltd. Postupak za pripremanje (2z,5z)-5-(3-kloro-4-((r)-2,3-dihidroksipropoksi)benziliden)-2-(propilimino)-3-(o-tolil)tiazolidin-4-ona i međuproizvodi koji se koriste u navedenom postupku
EA036075B1 (ru) 2014-12-11 2020-09-23 Актелион Фармасьютиклз Лтд Схема дозирования для селективного агониста рецептора s1p1
MA41139B1 (fr) 2014-12-11 2026-02-27 Laboratoires Juvise Pharmaceuticals Combinaison pharmaceutique comprenant du ponesimod et son utilisation dans le traitement de la sclérose en plaque
JOP20190207A1 (ar) 2017-03-14 2019-09-10 Actelion Pharmaceuticals Ltd تركيبة صيدلانية تشتمل على بونيسيمود
WO2019060147A1 (en) * 2017-09-19 2019-03-28 Teva Pharmaceuticals Usa, Inc. NEW CRYSTALLINE POLYMORPHE FROM PONESIMOD
US11014897B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms comprising a thiazolidinone compound, compositions and methods of use thereof
US11014940B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Thiazolidinone and oxazolidinone compounds and formulations
US11013723B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms of a thiazolidinone compound, compositions and methods of use thereof
US11186556B1 (en) 2018-10-16 2021-11-30 Celgene Corporation Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof
EP3997076A1 (de) * 2019-07-10 2022-05-18 Bayer Aktiengesellschaft Verfahren zur herstellung von 2-(phenylimino)-1,3-thiazolidin-4-onen
KR20220034818A (ko) * 2019-07-10 2022-03-18 바이엘 악티엔게젤샤프트 2-(페닐이미노)-1,3-티아졸리딘-4-온의 제조 방법
WO2021084068A1 (en) 2019-10-31 2021-05-06 Idorsia Pharmaceuticals Ltd Combination of a cxcr7 antagonist with an s1p1 receptor modulator
KR20200019639A (ko) 2020-01-30 2020-02-24 전대연 만남의 스마트 도착시스템
JP2023513623A (ja) * 2020-02-18 2023-03-31 バイエル・アクチエンゲゼルシヤフト ２－（フェニルイミノ）－３－アルキル－１，３－チアゾリジン－４－オン類の製造方法
EP4387960A1 (en) 2021-08-17 2024-06-26 Teva Czech Industries s.r.o Polymorphs of ponesimod
EP4212156A1 (en) 2022-01-13 2023-07-19 Abivax Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator
WO2023152691A1 (en) * 2022-02-10 2023-08-17 Metrochem Api Pvt Ltd Process for the preparation of ponesimod and its intermediates thereof
CN117924210A (zh) * 2024-01-22 2024-04-26 赣南师范大学 一种2-亚氨基噻唑烷-4-酮类化合物的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005054215A1 (en) * 2003-11-21 2005-06-16 Actelion Pharmaceuticals Ltd 5-(benz- (z) -ylidene) -thiazolidin-4-one derivatives as immunosuppressant agents

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OA03835A (fr) * 1970-07-17 1971-12-24 Rhone Poulenc Sa Nouveaux dérivés de la thiazolidine, leur préparation et les compositions qui les contiennent.
PL166269B1 (pl) 1990-04-27 1995-04-28 Orion Yh Tyma Oy Sposób wytwarzania nowych farmakologicznie aktywnych pochodnych katecholul PL PL PL PL PL
TW221689B (enExample) * 1991-08-27 1994-03-11 Otsuka Pharma Co Ltd
DE69429641T2 (de) * 1993-02-26 2002-08-29 Otsuka Pharmaceutical Co., Ltd. Thiazole oder imidazole derivate als maillard reaktion inhibitoren
KR960022486A (ko) 1994-12-29 1996-07-18 김준웅 신규 티아졸리딘-4-온 유도체
US6353006B1 (en) * 1999-01-14 2002-03-05 Bayer Corporation Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents
DE60038687T2 (de) 1999-09-14 2009-05-28 Shionogi & Co., Ltd. 2-imino-1,3-thiazin-derivate
AU767923C (en) * 1999-11-12 2005-03-24 Fujimoto Co., Ltd. Novel 2-(N-cyanoimino)thiazolidin-4-one derivatives
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AU2003255528B2 (en) 2002-07-10 2009-07-16 Merck Serono Sa Azolidinone-vinyl fused-benzene derivatives
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EP1567112B1 (en) * 2002-11-22 2008-10-15 Smithkline Beecham Corporation THIAZOLIDIN-4-ONES FOR INHIBITING hYAK3 PROTEINS
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GB0819182D0 (en) * 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms

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WO2005054215A1 (en) * 2003-11-21 2005-06-16 Actelion Pharmaceuticals Ltd 5-(benz- (z) -ylidene) -thiazolidin-4-one derivatives as immunosuppressant agents

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Also Published As

Publication number Publication date
EP2094676A2 (en) 2009-09-02
DK2489662T3 (da) 2014-10-20
CN103087004A (zh) 2013-05-08
BRPI0718986A2 (pt) 2014-02-11
US20100317867A1 (en) 2010-12-16
IL198847A (en) 2015-07-30
WO2008062376A2 (en) 2008-05-29
CA2669069A1 (en) 2008-05-29
EP2489662A1 (en) 2012-08-22
US20110201821A2 (en) 2011-08-18
IL198847A0 (en) 2010-02-17
JP2010510976A (ja) 2010-04-08
US8263780B2 (en) 2012-09-11
DK2094676T3 (da) 2013-06-10
KR20090081009A (ko) 2009-07-27
CA2669069C (en) 2015-02-17
WO2008062376A3 (en) 2008-07-10
CN101541772B (zh) 2013-04-17
CN101541772A (zh) 2009-09-23
TWI460166B (zh) 2014-11-11
MX2009005048A (es) 2009-05-25
TW200831474A (en) 2008-08-01
ES2410793T3 (es) 2013-07-03
KR101255879B1 (ko) 2013-04-17
EP2094676B1 (en) 2013-04-10
JP4669564B2 (ja) 2011-04-13
AU2007323042A1 (en) 2008-05-29
EP2489662B1 (en) 2014-08-06
ES2523401T3 (es) 2014-11-25

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