MX2009005048A - Nuevo proceso para la preparacion de derivados de 2-imino-tiazolidin-4-ona. - Google Patents

Nuevo proceso para la preparacion de derivados de 2-imino-tiazolidin-4-ona.

Info

Publication number
MX2009005048A
MX2009005048A MX2009005048A MX2009005048A MX2009005048A MX 2009005048 A MX2009005048 A MX 2009005048A MX 2009005048 A MX2009005048 A MX 2009005048A MX 2009005048 A MX2009005048 A MX 2009005048A MX 2009005048 A MX2009005048 A MX 2009005048A
Authority
MX
Mexico
Prior art keywords
thiazolidin
derivatives
preparation
imino
new process
Prior art date
Application number
MX2009005048A
Other languages
English (en)
Spanish (es)
Inventor
Martin Bolli
Stefan Abele
Gunther Schmidt
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of MX2009005048A publication Critical patent/MX2009005048A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54—Nitrogen and either oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MX2009005048A 2006-11-23 2007-11-22 Nuevo proceso para la preparacion de derivados de 2-imino-tiazolidin-4-ona. MX2009005048A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2006054409 2006-11-23
PCT/IB2007/054752 WO2008062376A2 (en) 2006-11-23 2007-11-22 New process for the preparation of 2-imino-thiazolidin-4-one derivatives

Publications (1)

Publication Number Publication Date
MX2009005048A true MX2009005048A (es) 2009-05-25

Family

ID=39316391

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009005048A MX2009005048A (es) 2006-11-23 2007-11-22 Nuevo proceso para la preparacion de derivados de 2-imino-tiazolidin-4-ona.

Country Status (13)

Country Link
US (1) US8263780B2 (enExample)
EP (2) EP2094676B1 (enExample)
JP (1) JP4669564B2 (enExample)
KR (1) KR101255879B1 (enExample)
CN (2) CN101541772B (enExample)
AU (1) AU2007323042B2 (enExample)
CA (1) CA2669069C (enExample)
DK (2) DK2489662T3 (enExample)
ES (2) ES2523401T3 (enExample)
IL (1) IL198847A (enExample)
MX (1) MX2009005048A (enExample)
TW (1) TWI460166B (enExample)
WO (1) WO2008062376A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE43833E1 (en) 2003-11-21 2012-11-27 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
US7435828B2 (en) 2003-11-21 2008-10-14 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
US8912340B2 (en) 2006-11-23 2014-12-16 Actelion Pharmaceuticals Ltd. Process for the preparation of 2-imino-thiazolidin-4-one derivatives
WO2009115954A1 (en) * 2008-03-17 2009-09-24 Actelion Pharmaceuticals Ltd Dosing regimen for a selective s1p1 receptor agonist
GB0819182D0 (en) 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms
SMT202000298T1 (it) 2012-08-17 2020-07-08 Actelion Pharmaceuticals Ltd Processo per la produzione di (2z,5z)-5-(3-cloro-4((r)-2,3-diidrossipropossi) benziliden)-2-(propilimmino)-3-(o-tolil)tiazolidin-4-one e intermedio usato in detto processo
MA41139B1 (fr) 2014-12-11 2026-02-27 Laboratoires Juvise Pharmaceuticals Combinaison pharmaceutique comprenant du ponesimod et son utilisation dans le traitement de la sclérose en plaque
DK3256125T3 (da) 2014-12-11 2022-03-21 Actelion Pharmaceuticals Ltd Doseringsregimen for ponesimod, en selektiv s1p1-receptoragonist
JOP20190207A1 (ar) 2017-03-14 2019-09-10 Actelion Pharmaceuticals Ltd تركيبة صيدلانية تشتمل على بونيسيمود
WO2019060147A1 (en) * 2017-09-19 2019-03-28 Teva Pharmaceuticals Usa, Inc. NEW CRYSTALLINE POLYMORPHE FROM PONESIMOD
US11014940B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Thiazolidinone and oxazolidinone compounds and formulations
US11186556B1 (en) 2018-10-16 2021-11-30 Celgene Corporation Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof
US11013723B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms of a thiazolidinone compound, compositions and methods of use thereof
US11014897B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms comprising a thiazolidinone compound, compositions and methods of use thereof
WO2021005081A1 (de) * 2019-07-10 2021-01-14 Bayer Aktiengesellschaft Verfahren zur herstellung von 2-(phenylimino)-1,3-thiazolidin-4-onen
BR112022000188A2 (pt) * 2019-07-10 2022-02-22 Bayer Ag Método para a preparação de 2-(fenilimino)-1,3-tiazolidin-4-onas
TW202131921A (zh) 2019-10-31 2021-09-01 瑞士商愛杜西亞製藥有限公司 Cxcr7拮抗劑與s1p1受體調節劑之組合
KR20200019639A (ko) 2020-01-30 2020-02-24 전대연 만남의 스마트 도착시스템
WO2021165187A1 (de) * 2020-02-18 2021-08-26 Bayer Aktiengesellschaft Verfahren zur herstellung von 2-(phenylimino)-3-alkyl-1,3-thiazolidin-4-onen
WO2023022896A1 (en) 2021-08-17 2023-02-23 Teva Czech Industries S.R.O Polymorphs of ponesimod
EP4212156A1 (en) 2022-01-13 2023-07-19 Abivax Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator
WO2023152691A1 (en) * 2022-02-10 2023-08-17 Metrochem Api Pvt Ltd Process for the preparation of ponesimod and its intermediates thereof
CN117924210B (zh) * 2024-01-22 2026-04-03 赣南师范大学 一种2-亚氨基噻唑烷-4-酮类化合物的制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3077402A (en) * 1954-12-06 1963-02-12 Polaroid Corp Photographic color processes, products, and compositions
NL270002A (enExample) * 1960-10-08
OA03835A (fr) * 1970-07-17 1971-12-24 Rhone Poulenc Sa Nouveaux dérivés de la thiazolidine, leur préparation et les compositions qui les contiennent.
EP0526598B1 (en) * 1990-04-27 1996-12-18 Orion-Yhtymà„ Oy New pharmacologically active catechol derivatives
TW221689B (enExample) * 1991-08-27 1994-03-11 Otsuka Pharma Co Ltd
AU669427B2 (en) * 1993-02-26 1996-06-06 Otsuka Pharmaceutical Co., Ltd. Thiazole or imidazole derivatives as maillard reaction inhibbitors
KR960022486A (ko) 1994-12-29 1996-07-18 김준웅 신규 티아졸리딘-4-온 유도체
US6353006B1 (en) * 1999-01-14 2002-03-05 Bayer Corporation Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents
CN1247553C (zh) 1999-09-14 2006-03-29 盐野义制药株式会社 2－亚氨基－1,3－噻嗪衍生物
KR100608416B1 (ko) * 1999-11-12 2006-08-02 후지모토 쿄다이 가부시키가이샤 2-(ｎ-시아노이미노)티아졸리딘-4-온 유도체
US20050019825A9 (en) * 2002-03-15 2005-01-27 Qing Dong Common ligand mimics: pseudothiohydantoins
EA011807B1 (ru) 2002-07-10 2009-06-30 Лаборатуар Сероно Са Азолидинонвинильные производные конденсированного бензола
GB0217152D0 (en) 2002-07-24 2002-09-04 Novartis Ag Organic compounds
JP2006509765A (ja) * 2002-11-22 2006-03-23 スミスクライン・ビーチャム・コーポレイション 新規化合物
US20040167192A1 (en) * 2003-01-16 2004-08-26 David Solow-Cordero Methods of treating conditions associated with an Edg-7 receptor
US7435828B2 (en) * 2003-11-21 2008-10-14 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
WO2005082901A1 (en) * 2004-02-25 2005-09-09 Smithkline Beecham Corporation Novel chemical compounds
WO2006094233A1 (en) * 2005-03-03 2006-09-08 Sirtris Pharmaceuticals, Inc. N,n'-dicyclic isothiourea sirtuin modulators
WO2009115954A1 (en) * 2008-03-17 2009-09-24 Actelion Pharmaceuticals Ltd Dosing regimen for a selective s1p1 receptor agonist
GB0819182D0 (en) * 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms

Also Published As

Publication number Publication date
WO2008062376A2 (en) 2008-05-29
CA2669069A1 (en) 2008-05-29
KR20090081009A (ko) 2009-07-27
WO2008062376A3 (en) 2008-07-10
JP4669564B2 (ja) 2011-04-13
CA2669069C (en) 2015-02-17
US8263780B2 (en) 2012-09-11
US20100317867A1 (en) 2010-12-16
AU2007323042A1 (en) 2008-05-29
KR101255879B1 (ko) 2013-04-17
JP2010510976A (ja) 2010-04-08
TWI460166B (zh) 2014-11-11
BRPI0718986A2 (pt) 2014-02-11
EP2094676B1 (en) 2013-04-10
DK2489662T3 (da) 2014-10-20
CN101541772B (zh) 2013-04-17
IL198847A (en) 2015-07-30
EP2094676A2 (en) 2009-09-02
DK2094676T3 (da) 2013-06-10
ES2523401T3 (es) 2014-11-25
US20110201821A2 (en) 2011-08-18
AU2007323042B2 (en) 2012-12-20
TW200831474A (en) 2008-08-01
EP2489662A1 (en) 2012-08-22
CN101541772A (zh) 2009-09-23
ES2410793T3 (es) 2013-07-03
IL198847A0 (en) 2010-02-17
EP2489662B1 (en) 2014-08-06
CN103087004A (zh) 2013-05-08

Similar Documents

Publication Publication Date Title
WO2008062376A3 (en) New process for the preparation of 2-imino-thiazolidin-4-one derivatives
UA95644C2 (ru) Пиридазиноновые производные, фармацевтическая композиция и способ лечения заболеваний
WO2007140385A3 (en) Thiazole compounds as cannabinoid receptor ligands and uses thereof
WO2007030361A3 (en) Benzimidazole thiophene compounds as plk inhibitors
MX2009007713A (es) Derivados de piridazina, procedimientos para su preparacion y su uso como fungicidas.
MX2007011023A (es) 2-(4-oxo-4h-quinazolin-3-il) acetamidas y su uso como antagonistas de vasopresin v3.
TW200745084A (en) Novel compounds
MX2010009022A (es) Derivados 16 alfa, 17 alfa-acetal glucocorticoesteroideos y su uso.
WO2009046842A3 (de) Thialzolderivate zur behandlung von krebs
TW200745004A (en) Novel compounds, their preparation and use
MY147994A (en) Azabiphenylaminobenzoic acid derivatives as dhodh inhibitors
TN2010000219A1 (en) 5-[(3,3,3-trifluoro-2-hydroxy-1-arylpropyl)amino]-1h-quinolin-2-ones, a process for their production and their use as anti-inflammatory agents
JO2682B1 (en) Derivatives of alkynil-8.1-naphthayridone, preparations thereof and therapeutic use thereof
UA96759C2 (en) 2-ARYLINDOLE DERIVATIVES AS mPGES-I INHIBITORS
TN2009000040A1 (en) 5,6-bisaryl-2-pyridine-carboxamide derivatives, preparation and application thereof in therapeutics as urotensin ii receptor antagonists
UA97369C2 (ru) Противоопухолевые соединения дигидропиран-2-она и фармацевтическая композиция на их основе
WO2011047055A3 (en) Novel mek inhibitors, useful in the treatment of diseases
MX2009000480A (es) Bencilaminas, un proceso para su produccion y su uso como agentes antiinflamatorios.
MY146671A (en) Tetrahydronaphthaline derivatives, methods for the production and use thereof as anti-inflammatory agents
SG158091A1 (en) Imidazoazepinone compounds
JO2749B1 (en) Indole-2-Wen derivatives bilaterally substituted at position 3, their preparation and therapeutic application
ZA200801875B (en) Isoquinolines as IGF-IR inhibitors
TW200639156A (en) New compounds
PL1758852T3 (pl) Podstawione związki cyklopentenu
TW200745122A (en) New compounds I

Legal Events

Date Code Title Description
FG Grant or registration