IL198847A - Process for making 2-imino-thiazolidine-4-on and several such histories - Google Patents

Process for making 2-imino-thiazolidine-4-on and several such histories

Info

Publication number
IL198847A
IL198847A IL198847A IL19884709A IL198847A IL 198847 A IL198847 A IL 198847A IL 198847 A IL198847 A IL 198847A IL 19884709 A IL19884709 A IL 19884709A IL 198847 A IL198847 A IL 198847A
Authority
IL
Israel
Prior art keywords
derivatives
thiazolidin
imino
preparation
Prior art date
Application number
IL198847A
Other languages
English (en)
Hebrew (he)
Other versions
IL198847A0 (en
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of IL198847A0 publication Critical patent/IL198847A0/en
Publication of IL198847A publication Critical patent/IL198847A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54—Nitrogen and either oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL198847A 2006-11-23 2009-05-20 Process for making 2-imino-thiazolidine-4-on and several such histories IL198847A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2006054409 2006-11-23
PCT/IB2007/054752 WO2008062376A2 (en) 2006-11-23 2007-11-22 New process for the preparation of 2-imino-thiazolidin-4-one derivatives

Publications (2)

Publication Number Publication Date
IL198847A0 IL198847A0 (en) 2010-02-17
IL198847A true IL198847A (en) 2015-07-30

Family

ID=39316391

Family Applications (1)

Application Number Title Priority Date Filing Date
IL198847A IL198847A (en) 2006-11-23 2009-05-20 Process for making 2-imino-thiazolidine-4-on and several such histories

Country Status (13)

Country Link
US (1) US8263780B2 (enExample)
EP (2) EP2094676B1 (enExample)
JP (1) JP4669564B2 (enExample)
KR (1) KR101255879B1 (enExample)
CN (2) CN103087004A (enExample)
AU (1) AU2007323042B2 (enExample)
CA (1) CA2669069C (enExample)
DK (2) DK2489662T3 (enExample)
ES (2) ES2410793T3 (enExample)
IL (1) IL198847A (enExample)
MX (1) MX2009005048A (enExample)
TW (1) TWI460166B (enExample)
WO (1) WO2008062376A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9340518B2 (en) 2012-08-17 2016-05-17 Actelion Pharmaceuticals Ltd. Process for the preparation of (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropdxy)benzylidene)-2-(propylimino)-3-(o-tolyl)thiazolidin-4-one and intermediate used in said process

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE43833E1 (en) 2003-11-21 2012-11-27 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
AU2004295047B2 (en) 2003-11-21 2011-03-10 Laboratoires Juvise Pharmaceuticals 5-(benz- (Z) -ylidene) -thiazolidin-4-one derivatives as immunosuppressant agents
US8912340B2 (en) 2006-11-23 2014-12-16 Actelion Pharmaceuticals Ltd. Process for the preparation of 2-imino-thiazolidin-4-one derivatives
DK2278960T4 (da) * 2008-03-17 2020-01-27 Actelion Pharmaceuticals Ltd Dosisregimen til en selektiv sip1 receptoragonist
GB0819182D0 (en) 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms
EA036075B1 (ru) 2014-12-11 2020-09-23 Актелион Фармасьютиклз Лтд Схема дозирования для селективного агониста рецептора s1p1
MA41139B1 (fr) 2014-12-11 2026-02-27 Laboratoires Juvise Pharmaceuticals Combinaison pharmaceutique comprenant du ponesimod et son utilisation dans le traitement de la sclérose en plaque
JOP20190207A1 (ar) 2017-03-14 2019-09-10 Actelion Pharmaceuticals Ltd تركيبة صيدلانية تشتمل على بونيسيمود
WO2019060147A1 (en) * 2017-09-19 2019-03-28 Teva Pharmaceuticals Usa, Inc. NEW CRYSTALLINE POLYMORPHE FROM PONESIMOD
US11014897B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms comprising a thiazolidinone compound, compositions and methods of use thereof
US11014940B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Thiazolidinone and oxazolidinone compounds and formulations
US11013723B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms of a thiazolidinone compound, compositions and methods of use thereof
US11186556B1 (en) 2018-10-16 2021-11-30 Celgene Corporation Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof
EP3997076A1 (de) * 2019-07-10 2022-05-18 Bayer Aktiengesellschaft Verfahren zur herstellung von 2-(phenylimino)-1,3-thiazolidin-4-onen
KR20220034818A (ko) * 2019-07-10 2022-03-18 바이엘 악티엔게젤샤프트 2-(페닐이미노)-1,3-티아졸리딘-4-온의 제조 방법
WO2021084068A1 (en) 2019-10-31 2021-05-06 Idorsia Pharmaceuticals Ltd Combination of a cxcr7 antagonist with an s1p1 receptor modulator
KR20200019639A (ko) 2020-01-30 2020-02-24 전대연 만남의 스마트 도착시스템
JP2023513623A (ja) * 2020-02-18 2023-03-31 バイエル・アクチエンゲゼルシヤフト ２－（フェニルイミノ）－３－アルキル－１，３－チアゾリジン－４－オン類の製造方法
EP4387960A1 (en) 2021-08-17 2024-06-26 Teva Czech Industries s.r.o Polymorphs of ponesimod
EP4212156A1 (en) 2022-01-13 2023-07-19 Abivax Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator
WO2023152691A1 (en) * 2022-02-10 2023-08-17 Metrochem Api Pvt Ltd Process for the preparation of ponesimod and its intermediates thereof
CN117924210A (zh) * 2024-01-22 2024-04-26 赣南师范大学 一种2-亚氨基噻唑烷-4-酮类化合物的制备方法

Family Cites Families (20)

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Publication number Priority date Publication date Assignee Title
US3077402A (en) * 1954-12-06 1963-02-12 Polaroid Corp Photographic color processes, products, and compositions
NL270002A (enExample) 1960-10-08
OA03835A (fr) * 1970-07-17 1971-12-24 Rhone Poulenc Sa Nouveaux dérivés de la thiazolidine, leur préparation et les compositions qui les contiennent.
PL166269B1 (pl) 1990-04-27 1995-04-28 Orion Yh Tyma Oy Sposób wytwarzania nowych farmakologicznie aktywnych pochodnych katecholul PL PL PL PL PL
TW221689B (enExample) * 1991-08-27 1994-03-11 Otsuka Pharma Co Ltd
DE69429641T2 (de) * 1993-02-26 2002-08-29 Otsuka Pharmaceutical Co., Ltd. Thiazole oder imidazole derivate als maillard reaktion inhibitoren
KR960022486A (ko) 1994-12-29 1996-07-18 김준웅 신규 티아졸리딘-4-온 유도체
US6353006B1 (en) * 1999-01-14 2002-03-05 Bayer Corporation Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents
DE60038687T2 (de) 1999-09-14 2009-05-28 Shionogi & Co., Ltd. 2-imino-1,3-thiazin-derivate
AU767923C (en) * 1999-11-12 2005-03-24 Fujimoto Co., Ltd. Novel 2-(N-cyanoimino)thiazolidin-4-one derivatives
US20050019825A9 (en) * 2002-03-15 2005-01-27 Qing Dong Common ligand mimics: pseudothiohydantoins
AU2003255528B2 (en) 2002-07-10 2009-07-16 Merck Serono Sa Azolidinone-vinyl fused-benzene derivatives
GB0217152D0 (en) 2002-07-24 2002-09-04 Novartis Ag Organic compounds
EP1567112B1 (en) * 2002-11-22 2008-10-15 Smithkline Beecham Corporation THIAZOLIDIN-4-ONES FOR INHIBITING hYAK3 PROTEINS
US20040167192A1 (en) * 2003-01-16 2004-08-26 David Solow-Cordero Methods of treating conditions associated with an Edg-7 receptor
AU2004295047B2 (en) * 2003-11-21 2011-03-10 Laboratoires Juvise Pharmaceuticals 5-(benz- (Z) -ylidene) -thiazolidin-4-one derivatives as immunosuppressant agents
EP1718642A4 (en) * 2004-02-25 2010-11-24 Glaxosmithkline Llc NEW CHEMICAL COMPOUNDS
WO2006094233A1 (en) * 2005-03-03 2006-09-08 Sirtris Pharmaceuticals, Inc. N,n'-dicyclic isothiourea sirtuin modulators
DK2278960T4 (da) * 2008-03-17 2020-01-27 Actelion Pharmaceuticals Ltd Dosisregimen til en selektiv sip1 receptoragonist
GB0819182D0 (en) * 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9340518B2 (en) 2012-08-17 2016-05-17 Actelion Pharmaceuticals Ltd. Process for the preparation of (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropdxy)benzylidene)-2-(propylimino)-3-(o-tolyl)thiazolidin-4-one and intermediate used in said process

Also Published As

Publication number Publication date
EP2094676A2 (en) 2009-09-02
DK2489662T3 (da) 2014-10-20
CN103087004A (zh) 2013-05-08
BRPI0718986A2 (pt) 2014-02-11
US20100317867A1 (en) 2010-12-16
WO2008062376A2 (en) 2008-05-29
CA2669069A1 (en) 2008-05-29
EP2489662A1 (en) 2012-08-22
US20110201821A2 (en) 2011-08-18
IL198847A0 (en) 2010-02-17
JP2010510976A (ja) 2010-04-08
AU2007323042B2 (en) 2012-12-20
US8263780B2 (en) 2012-09-11
DK2094676T3 (da) 2013-06-10
KR20090081009A (ko) 2009-07-27
CA2669069C (en) 2015-02-17
WO2008062376A3 (en) 2008-07-10
CN101541772B (zh) 2013-04-17
CN101541772A (zh) 2009-09-23
TWI460166B (zh) 2014-11-11
MX2009005048A (es) 2009-05-25
TW200831474A (en) 2008-08-01
ES2410793T3 (es) 2013-07-03
KR101255879B1 (ko) 2013-04-17
EP2094676B1 (en) 2013-04-10
JP4669564B2 (ja) 2011-04-13
AU2007323042A1 (en) 2008-05-29
EP2489662B1 (en) 2014-08-06
ES2523401T3 (es) 2014-11-25

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