AU2002363339B2 - Stable liquid pharmaceutical formulation of IGG antibodies - Google Patents
Stable liquid pharmaceutical formulation of IGG antibodies Download PDFInfo
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- AU2002363339B2 AU2002363339B2 AU2002363339A AU2002363339A AU2002363339B2 AU 2002363339 B2 AU2002363339 B2 AU 2002363339B2 AU 2002363339 A AU2002363339 A AU 2002363339A AU 2002363339 A AU2002363339 A AU 2002363339A AU 2002363339 B2 AU2002363339 B2 AU 2002363339B2
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- Prior art keywords
- clear
- antibody
- formulation
- buffer
- succinate
- Prior art date
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K9/0012—Galenical forms characterised by the site of application
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/244—Interleukins [IL]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/244—Interleukins [IL]
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- C—CHEMISTRY; METALLURGY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
- C07K16/2854—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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Landscapes
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- Transplantation (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US33750901P | 2001-11-08 | 2001-11-08 | |
| US60/337,509 | 2001-11-08 | ||
| PCT/US2002/036093 WO2003039485A2 (en) | 2001-11-08 | 2002-11-08 | Stable liquid pharmaceutical formulation of igg antibodies |
Publications (2)
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| AU2002363339A1 AU2002363339A1 (en) | 2003-07-24 |
| AU2002363339B2 true AU2002363339B2 (en) | 2008-02-07 |
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| AU2002363339A Ceased AU2002363339B2 (en) | 2001-11-08 | 2002-11-08 | Stable liquid pharmaceutical formulation of IGG antibodies |
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| EP (1) | EP1441589B1 (enExample) |
| JP (2) | JP5290489B2 (enExample) |
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| CA (1) | CA2466034C (enExample) |
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| IL (2) | IL161677A0 (enExample) |
| LU (1) | LU93314I2 (enExample) |
| NZ (1) | NZ532896A (enExample) |
| PT (1) | PT1441589E (enExample) |
| WO (1) | WO2003039485A2 (enExample) |
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| US6761888B1 (en) | 2000-05-26 | 2004-07-13 | Neuralab Limited | Passive immunization treatment of Alzheimer's disease |
| TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
| US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| US7588766B1 (en) | 2000-05-26 | 2009-09-15 | Elan Pharma International Limited | Treatment of amyloidogenic disease |
| US8703126B2 (en) | 2000-10-12 | 2014-04-22 | Genentech, Inc. | Reduced-viscosity concentrated protein formulations |
| IL155002A0 (en) * | 2000-10-12 | 2003-10-31 | Genentech Inc | Reduced-viscosity concentrated protein formulations |
| PE20020574A1 (es) | 2000-12-06 | 2002-07-02 | Wyeth Corp | Anticuerpos humanizados que reconocen el peptido amiloideo beta |
| US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
| US20030138417A1 (en) * | 2001-11-08 | 2003-07-24 | Kaisheva Elizabet A. | Stable liquid pharmaceutical formulation of IgG antibodies |
| US20070148171A1 (en) * | 2002-09-27 | 2007-06-28 | Xencor, Inc. | Optimized anti-CD30 antibodies |
| MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
| US20040002451A1 (en) * | 2002-06-20 | 2004-01-01 | Bruce Kerwin | Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing |
| CN1671741A (zh) * | 2002-06-21 | 2005-09-21 | 拜奥根Idec公司 | 浓缩抗体的缓冲剂制剂及其使用方法 |
| US20040033228A1 (en) | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
| MY150740A (en) * | 2002-10-24 | 2014-02-28 | Abbvie Biotechnology Ltd | Low dose methods for treating disorders in which tnf? activity is detrimental |
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| US20040208869A1 (en) * | 2003-01-30 | 2004-10-21 | Medimmune, Inc. | Uses of anti-integrin alphanubeta3 antibody formulations |
| US20040208870A1 (en) * | 2003-01-30 | 2004-10-21 | Medimmune, Inc. | Stabilized high concentration anti-integrin alphanubeta3 antibody formulations |
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| US5091178A (en) * | 1986-02-21 | 1992-02-25 | Oncogen | Tumor therapy with biologically active anti-tumor antibodies |
| WO1989011297A1 (en) | 1988-05-27 | 1989-11-30 | Centocor, Inc. | Freeze-dried formulation for antibody products |
| AU4803890A (en) * | 1988-12-15 | 1990-07-10 | Invitron Corporation | Use of basic amino acids to solubilize immunoglobulins |
| CA2049342A1 (en) | 1989-03-27 | 1990-09-28 | Sally Bolmer | Formulations for stabilizing of igm antibodies |
| US6165467A (en) * | 1991-07-20 | 2000-12-26 | Yoshihide Hagiwara | Stabilized human monoclonal antibody preparation |
| ATE216590T1 (de) * | 1995-02-06 | 2002-05-15 | Genetics Inst | Arzneimittelformulierungen für il-12 |
| US6685940B2 (en) * | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
| US6267958B1 (en) * | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| MX9800684A (es) * | 1995-07-27 | 1998-04-30 | Genentech Inc | Formulacion de proteinas liofilizadas isotonicas estables. |
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| AU3921600A (en) | 1999-03-25 | 2000-10-09 | Abbott Gmbh & Co. Kg | Human antibodies that bind human il-12 and methods for producing |
| GB0113179D0 (en) * | 2001-05-31 | 2001-07-25 | Novartis Ag | Organic compounds |
| US20030138417A1 (en) * | 2001-11-08 | 2003-07-24 | Kaisheva Elizabet A. | Stable liquid pharmaceutical formulation of IgG antibodies |
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2002
- 2002-11-08 US US10/291,528 patent/US20030138417A1/en not_active Abandoned
- 2002-11-08 NZ NZ532896A patent/NZ532896A/en not_active IP Right Cessation
- 2002-11-08 ES ES02802895T patent/ES2392073T3/es not_active Expired - Lifetime
- 2002-11-08 DK DK02802895.9T patent/DK1441589T3/da active
- 2002-11-08 IL IL16167702A patent/IL161677A0/xx unknown
- 2002-11-08 PT PT02802895T patent/PT1441589E/pt unknown
- 2002-11-08 CA CA2466034A patent/CA2466034C/en not_active Expired - Lifetime
- 2002-11-08 EP EP02802895A patent/EP1441589B1/en not_active Expired - Lifetime
- 2002-11-08 WO PCT/US2002/036093 patent/WO2003039485A2/en not_active Ceased
- 2002-11-08 AT AT02802895T patent/ATE556591T1/de active
- 2002-11-08 JP JP2003541777A patent/JP5290489B2/ja not_active Expired - Fee Related
- 2002-11-08 AU AU2002363339A patent/AU2002363339B2/en not_active Ceased
- 2002-11-08 KR KR1020047006962A patent/KR100913714B1/ko not_active Expired - Fee Related
- 2002-11-08 CN CNB028267273A patent/CN1292655C/zh not_active Expired - Fee Related
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2004
- 2004-04-29 IL IL161677A patent/IL161677A/en active IP Right Grant
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2010
- 2010-11-24 US US12/954,512 patent/US20110070231A1/en not_active Abandoned
- 2010-12-10 JP JP2010276222A patent/JP2011068675A/ja active Pending
-
2011
- 2011-09-06 US US13/226,372 patent/US8465739B2/en not_active Expired - Fee Related
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2016
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- 2016-12-09 CY CY2016044C patent/CY2016044I1/el unknown
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| WO1997045140A1 (en) * | 1996-05-24 | 1997-12-04 | Glaxo Group Limited | Concentrated antibody preparation |
| WO1998056418A1 (en) * | 1997-06-13 | 1998-12-17 | Genentech, Inc. | Stabilized antibody formulation |
| AU2002213441B2 (en) * | 2000-10-12 | 2006-10-26 | Genentech, Inc. | Reduced-viscosity concentrated protein formulations |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2466034A1 (en) | 2003-05-15 |
| ES2392073T3 (es) | 2012-12-04 |
| CY2016044I2 (el) | 2017-07-12 |
| PT1441589E (pt) | 2012-08-13 |
| ATE556591T1 (de) | 2012-05-15 |
| CA2466034C (en) | 2012-12-18 |
| EP1441589A4 (en) | 2007-07-04 |
| US20110318343A1 (en) | 2011-12-29 |
| CY2016044I1 (el) | 2017-07-12 |
| CN1612689A (zh) | 2005-05-04 |
| NZ532896A (en) | 2007-08-31 |
| LU93314I2 (enExample) | 2019-11-20 |
| HK1074750A1 (en) | 2005-11-25 |
| DK1441589T3 (da) | 2012-08-06 |
| JP2005508981A (ja) | 2005-04-07 |
| EP1441589B1 (en) | 2012-05-09 |
| US8465739B2 (en) | 2013-06-18 |
| IL161677A (en) | 2010-06-16 |
| WO2003039485A3 (en) | 2004-02-12 |
| KR100913714B1 (ko) | 2009-08-24 |
| US20110070231A1 (en) | 2011-03-24 |
| IL161677A0 (en) | 2004-09-27 |
| EP1441589A2 (en) | 2004-08-04 |
| JP2011068675A (ja) | 2011-04-07 |
| KR20050044365A (ko) | 2005-05-12 |
| US20030138417A1 (en) | 2003-07-24 |
| CN1292655C (zh) | 2007-01-03 |
| JP5290489B2 (ja) | 2013-09-18 |
| WO2003039485A2 (en) | 2003-05-15 |
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