MX2013010737A - Novedosos metodos de purificacion de proteinas. - Google Patents

Novedosos metodos de purificacion de proteinas.

Info

Publication number
MX2013010737A
MX2013010737A MX2013010737A MX2013010737A MX2013010737A MX 2013010737 A MX2013010737 A MX 2013010737A MX 2013010737 A MX2013010737 A MX 2013010737A MX 2013010737 A MX2013010737 A MX 2013010737A MX 2013010737 A MX2013010737 A MX 2013010737A
Authority
MX
Mexico
Prior art keywords
surfactant
protein purification
purification methods
novel protein
protein
Prior art date
Application number
MX2013010737A
Other languages
English (en)
Inventor
Jun Liu
Arick Brown
Junyan Ji
Yuchang John Wang
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46931857&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2013010737(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2013010737A publication Critical patent/MX2013010737A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02—Recovery or purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14311—Parvovirus, e.g. minute virus of mice
    • C12N2750/14351—Methods of production or purification of viral material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Water Supply & Treatment (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención proporciona métodos para reducir incrustación de membranas de ultrafiltración en procesos en donde partículas de virus se retiran de soluciones acuosas que comprenden partículas de virus y por lo menos una proteína mediante la adición de un agente no iónico, surfactante o no surfactante a la solución acuosa antes de filtración. La invención también proporciona métodos para disociar agregados de proteína o para reducir la formación de agregados de proteína mediante la adición de un agente no iónico, surfactante o no surfactante a la solución de proteína.
MX2013010737A 2011-03-25 2012-03-23 Novedosos metodos de purificacion de proteinas. MX2013010737A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161467897P 2011-03-25 2011-03-25
PCT/US2012/030265 WO2012134987A1 (en) 2011-03-25 2012-03-23 Novel protein purification methods

Publications (1)

Publication Number Publication Date
MX2013010737A true MX2013010737A (es) 2014-03-12

Family

ID=46931857

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013010737A MX2013010737A (es) 2011-03-25 2012-03-23 Novedosos metodos de purificacion de proteinas.

Country Status (18)

Country Link
US (1) US10906934B2 (es)
EP (1) EP2697369B1 (es)
KR (1) KR20140022845A (es)
CN (1) CN103582700B (es)
AU (1) AU2012237026A1 (es)
BR (1) BR112013024521A2 (es)
CA (1) CA2830640A1 (es)
ES (1) ES2685079T3 (es)
HK (1) HK1194434A1 (es)
HR (1) HRP20181357T1 (es)
IL (1) IL228438A0 (es)
MX (1) MX2013010737A (es)
PL (1) PL2697369T3 (es)
RU (1) RU2013147609A (es)
SG (1) SG193564A1 (es)
SI (1) SI2697369T1 (es)
TR (1) TR201810703T4 (es)
WO (1) WO2012134987A1 (es)

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MY161866A (en) 2006-09-13 2017-05-15 Abbvie Inc Cell culture improvements
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
SG10201702922VA (en) 2008-10-20 2017-06-29 Abbvie Inc Isolation and purification of antibodies using protein a affinity chromatography
CN104974251A (zh) 2008-10-20 2015-10-14 Abbvie公司 在抗体纯化过程中的病毒灭活
WO2012134987A1 (en) 2011-03-25 2012-10-04 Genentech, Inc. Novel protein purification methods
US8933009B2 (en) 2013-03-12 2015-01-13 Ecolab Usa Inc. Surfactant blends for cleaning filtration membranes
CA2930687C (en) 2013-11-15 2024-04-23 Genentech, Inc. Methods for viral inactivation using eco-friendly detergents
US20170245513A1 (en) * 2014-08-27 2017-08-31 Godo Shusei Co., Ltd. Lactase solution and milk using same
EP3371302B1 (en) * 2015-11-05 2024-01-03 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method for the separation of virus compositions including depletion and purification thereof
KR102316263B1 (ko) 2017-06-12 2021-10-26 아사히 가세이 메디컬 가부시키가이샤 단백질 함유액의 여과 방법
US11291958B2 (en) 2017-09-29 2022-04-05 Ecolab Usa Inc. Use of extended surfactants in process membrane cleaning
AU2019222696B2 (en) 2018-02-14 2024-02-29 Ecolab Usa Inc. Compositions and methods for the reduction of biofilm and spores from membranes
EP3546475A1 (en) * 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
WO2020227144A1 (en) 2019-05-03 2020-11-12 Genentech, Inc. Methods of reducing the enzymatic hydrolysis activity rate in a composition obtained from a purification platform
CN115279780A (zh) * 2019-12-12 2022-11-01 营养与生物科学美国1有限责任公司 蛋白质生物工艺
CA3183021A1 (en) * 2020-07-10 2022-01-13 Myles Lindsay Method for obtaining a composition comprising human plasma-derived immunoglobulin m
KR20230043132A (ko) * 2020-07-15 2023-03-30 뉴트리션 ＆ 바이오사이언시즈 유에스에이 1, 엘엘씨 표면 상의 오염이 감소된 생물공정
KR20230098589A (ko) 2020-10-30 2023-07-04 제넨테크, 인크. 감소된 가수분해 효소 활성률을 갖는 약제학적 조성물을 수득하기 위한 정제 플랫폼
CN115779683B (zh) * 2022-12-16 2024-03-22 康日百奥生物科技(苏州)有限公司 除病毒过滤方法

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US4618533A (en) 1984-11-30 1986-10-21 Millipore Corporation Porous membrane having hydrophilic surface and process
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5017292A (en) 1990-05-10 1991-05-21 Millipore Corporation Membrane, process and system for isolating virus from solution
AU3178993A (en) 1991-11-25 1993-06-28 Enzon, Inc. Multivalent antigen-binding proteins
DE69520042T2 (de) 1994-07-28 2001-07-19 Millipore Corp Porösesverbundmembran und verfahren
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
US5888401A (en) 1996-09-16 1999-03-30 Union Camp Corporation Method and apparatus for reducing membrane fouling
US20070059302A1 (en) * 1997-04-07 2007-03-15 Genentech, Inc. Anti-vegf antibodies
US6096872A (en) * 1997-10-14 2000-08-01 Ortho Diagnostic Systems, Inc. Viral clearance process
AU2001278716A1 (en) 2000-08-10 2002-02-25 Chugai Seiyaku Kabushiki Kaisha Method of inhibiting antibody-containing solution from coagulating or becoming turbid
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WO2003066669A2 (en) 2002-02-04 2003-08-14 Millipore Corporation Process for removing protein aggregates and virus from a protein solution
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CA2489123C (en) * 2002-06-14 2011-03-15 Centocor, Inc. Use of a clathrate modifier to promote passage of proteins during nanofiltration
CA2490423A1 (en) * 2002-06-21 2003-12-31 Biogen Idec Inc. Buffered formulations for concentrating antibodies and methods of use thereof
CA2496918A1 (en) * 2002-08-28 2004-03-11 Introgen Therapeutics Inc. Chromatographic methods for adenovirus purification
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AU2005229674B2 (en) 2004-11-18 2010-11-04 Kedrion Melville Inc. Low concentration solvent/detergent process of immuneglobulin with pre-treatment
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US8741600B2 (en) 2007-06-19 2014-06-03 Asahi Kasei Kabushiki Kaisha Method for separation of immunoglobulin monomers
WO2010109920A1 (ja) * 2009-03-27 2010-09-30 旭化成メディカル株式会社 高濃度モノクローナル抗体溶液中のウイルス除去方法
SG178276A1 (en) * 2009-08-06 2012-03-29 Genentech Inc Method to improve virus removal in protein purification
WO2012134987A1 (en) 2011-03-25 2012-10-04 Genentech, Inc. Novel protein purification methods

Also Published As

Publication number Publication date
CN103582700A (zh) 2014-02-12
HK1194434A1 (zh) 2014-10-17
EP2697369A1 (en) 2014-02-19
CA2830640A1 (en) 2012-10-04
AU2012237026A1 (en) 2013-10-24
NZ615579A (en) 2016-09-30
US20140309403A1 (en) 2014-10-16
ES2685079T3 (es) 2018-10-05
CN103582700B (zh) 2016-08-17
TR201810703T4 (tr) 2018-08-27
KR20140022845A (ko) 2014-02-25
SI2697369T1 (sl) 2018-10-30
US10906934B2 (en) 2021-02-02
EP2697369B1 (en) 2018-06-27
WO2012134987A1 (en) 2012-10-04
IL228438A0 (en) 2013-12-31
PL2697369T3 (pl) 2018-12-31
BR112013024521A2 (pt) 2019-09-24
SG193564A1 (en) 2013-10-30
RU2013147609A (ru) 2015-04-27
EP2697369A4 (en) 2015-01-21
HRP20181357T1 (hr) 2018-10-19

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