AU2002363339B2 - Stable liquid pharmaceutical formulation of IGG antibodies - Google Patents
Stable liquid pharmaceutical formulation of IGG antibodies Download PDFInfo
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- AU2002363339B2 AU2002363339B2 AU2002363339A AU2002363339A AU2002363339B2 AU 2002363339 B2 AU2002363339 B2 AU 2002363339B2 AU 2002363339 A AU2002363339 A AU 2002363339A AU 2002363339 A AU2002363339 A AU 2002363339A AU 2002363339 B2 AU2002363339 B2 AU 2002363339B2
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- Prior art keywords
- clear
- antibody
- formulation
- buffer
- succinate
- Prior art date
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/244—Interleukins [IL]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/246—IL-2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
- C07K16/2854—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Microbiology (AREA)
- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33750901P | 2001-11-08 | 2001-11-08 | |
| US60/337,509 | 2001-11-08 | ||
| PCT/US2002/036093 WO2003039485A2 (en) | 2001-11-08 | 2002-11-08 | Stable liquid pharmaceutical formulation of igg antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2002363339A1 AU2002363339A1 (en) | 2003-07-24 |
| AU2002363339B2 true AU2002363339B2 (en) | 2008-02-07 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002363339A Ceased AU2002363339B2 (en) | 2001-11-08 | 2002-11-08 | Stable liquid pharmaceutical formulation of IGG antibodies |
Country Status (16)
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| US (3) | US20030138417A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1441589B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5290489B2 (cg-RX-API-DMAC7.html) |
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| CN (1) | CN1292655C (cg-RX-API-DMAC7.html) |
| AT (1) | ATE556591T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2002363339B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2466034C (cg-RX-API-DMAC7.html) |
| CY (1) | CY2016044I2 (cg-RX-API-DMAC7.html) |
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| ES (1) | ES2392073T3 (cg-RX-API-DMAC7.html) |
| IL (2) | IL161677A0 (cg-RX-API-DMAC7.html) |
| LU (1) | LU93314I2 (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ532896A (cg-RX-API-DMAC7.html) |
| PT (1) | PT1441589E (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003039485A2 (cg-RX-API-DMAC7.html) |
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| US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
| US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| US6761888B1 (en) | 2000-05-26 | 2004-07-13 | Neuralab Limited | Passive immunization treatment of Alzheimer's disease |
| US7588766B1 (en) | 2000-05-26 | 2009-09-15 | Elan Pharma International Limited | Treatment of amyloidogenic disease |
| US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
| ATE442862T2 (de) * | 2000-10-12 | 2009-10-15 | Genentech Inc | Niederviskose konzentrierte proteinformulierungen |
| US8703126B2 (en) | 2000-10-12 | 2014-04-22 | Genentech, Inc. | Reduced-viscosity concentrated protein formulations |
| TWI255272B (en) | 2000-12-06 | 2006-05-21 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
| US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
| CA2466034C (en) * | 2001-11-08 | 2012-12-18 | Protein Design Labs, Inc. | Stable aqueous pharmaceutical formulations of daclizumab antibodies |
| US20070148171A1 (en) * | 2002-09-27 | 2007-06-28 | Xencor, Inc. | Optimized anti-CD30 antibodies |
| MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
| US20040002451A1 (en) * | 2002-06-20 | 2004-01-01 | Bruce Kerwin | Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing |
| WO2004001007A2 (en) * | 2002-06-21 | 2003-12-31 | Idec Pharmaceuticals Corporation | Buffered formulations for concentrating antibodies and methods of use thereof |
| US20040033228A1 (en) | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
| MY150740A (en) * | 2002-10-24 | 2014-02-28 | Abbvie Biotechnology Ltd | Low dose methods for treating disorders in which tnf? activity is detrimental |
| US20040191243A1 (en) * | 2002-12-13 | 2004-09-30 | Bei Chen | System and method for stabilizing antibodies with histidine |
| US20040208869A1 (en) * | 2003-01-30 | 2004-10-21 | Medimmune, Inc. | Uses of anti-integrin alphanubeta3 antibody formulations |
| US20040208870A1 (en) * | 2003-01-30 | 2004-10-21 | Medimmune, Inc. | Stabilized high concentration anti-integrin alphanubeta3 antibody formulations |
| CN100353997C (zh) * | 2003-02-28 | 2007-12-12 | 中外制药株式会社 | 稳定的含蛋白质的制剂 |
| BRPI0403964B8 (pt) * | 2003-04-04 | 2021-05-25 | Genentech Inc | formulações líquidas estáveis, artigo manufaturado e uso dessas formulações para o tratamento de disfunção mediada por ige |
| US20050158303A1 (en) * | 2003-04-04 | 2005-07-21 | Genentech, Inc. | Methods of treating IgE-mediated disorders comprising the administration of high concentration anti-IgE antibody formulations |
| TWI306458B (en) | 2003-05-30 | 2009-02-21 | Elan Pharma Int Ltd | Humanized antibodies that recognize beta amyloid peptide |
| WO2005052004A2 (en) * | 2003-11-28 | 2005-06-09 | Micromet Ag | Compositions comprising polypeptides |
| US20050136055A1 (en) * | 2003-12-22 | 2005-06-23 | Pfizer Inc | CD40 antibody formulation and methods |
| PL2177537T3 (pl) * | 2004-01-09 | 2012-06-29 | Pfizer | Przeciwciała przeciw MadCAM |
| US20060008415A1 (en) * | 2004-06-25 | 2006-01-12 | Protein Design Labs, Inc. | Stable liquid and lyophilized formulation of proteins |
| US20060051347A1 (en) | 2004-09-09 | 2006-03-09 | Winter Charles M | Process for concentration of antibodies and therapeutic products thereof |
| JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
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| JP2025509702A (ja) | 2022-03-14 | 2025-04-11 | ラムキャップ バイオ ガンマ エージー | ＧＰＣ３陽性悪性細胞を標的殺傷するための二重特異性ＧＰＣ３ｘＣＤ２８抗体およびＧＰＣ３ｘＣＤ３抗体ならびにそれらの組み合わせ |
| GB202214120D0 (en) | 2022-09-27 | 2022-11-09 | King S College London | Compositions comprising NKG2D, CXCR2, and DAP10/DAP12 fusion polypeptides and methods of use thereof |
| EP4389762A1 (en) | 2022-12-23 | 2024-06-26 | Ospedale San Raffaele S.r.l. | Inhibitors of dux4 activity and their use in therapy. |
| WO2025140467A1 (zh) * | 2023-12-29 | 2025-07-03 | 上海复宏汉霖生物技术股份有限公司 | 稳定的高浓度抗pd-1抗体药物制剂 |
| WO2025196207A1 (en) | 2024-03-20 | 2025-09-25 | King's College London | Compositions and methods for use in depleting senescent cells and treating aging |
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- 2002-11-08 AT AT02802895T patent/ATE556591T1/de active
- 2002-11-08 US US10/291,528 patent/US20030138417A1/en not_active Abandoned
- 2002-11-08 WO PCT/US2002/036093 patent/WO2003039485A2/en not_active Ceased
- 2002-11-08 KR KR1020047006962A patent/KR100913714B1/ko not_active Expired - Fee Related
- 2002-11-08 EP EP02802895A patent/EP1441589B1/en not_active Expired - Lifetime
- 2002-11-08 JP JP2003541777A patent/JP5290489B2/ja not_active Expired - Fee Related
- 2002-11-08 NZ NZ532896A patent/NZ532896A/en not_active IP Right Cessation
- 2002-11-08 CN CNB028267273A patent/CN1292655C/zh not_active Expired - Fee Related
- 2002-11-08 AU AU2002363339A patent/AU2002363339B2/en not_active Ceased
- 2002-11-08 DK DK02802895.9T patent/DK1441589T3/da active
- 2002-11-08 PT PT02802895T patent/PT1441589E/pt unknown
- 2002-11-08 ES ES02802895T patent/ES2392073T3/es not_active Expired - Lifetime
- 2002-11-08 IL IL16167702A patent/IL161677A0/xx unknown
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2004
- 2004-04-29 IL IL161677A patent/IL161677A/en active IP Right Grant
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2010
- 2010-11-24 US US12/954,512 patent/US20110070231A1/en not_active Abandoned
- 2010-12-10 JP JP2010276222A patent/JP2011068675A/ja active Pending
-
2011
- 2011-09-06 US US13/226,372 patent/US8465739B2/en not_active Expired - Fee Related
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2016
- 2016-11-17 LU LU93314C patent/LU93314I2/fr unknown
- 2016-12-09 CY CY2016044C patent/CY2016044I2/el unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| HK1074750A1 (en) | 2005-11-25 |
| EP1441589A4 (en) | 2007-07-04 |
| US20110318343A1 (en) | 2011-12-29 |
| IL161677A (en) | 2010-06-16 |
| CN1612689A (zh) | 2005-05-04 |
| US20110070231A1 (en) | 2011-03-24 |
| WO2003039485A3 (en) | 2004-02-12 |
| ATE556591T1 (de) | 2012-05-15 |
| CN1292655C (zh) | 2007-01-03 |
| PT1441589E (pt) | 2012-08-13 |
| CA2466034A1 (en) | 2003-05-15 |
| JP5290489B2 (ja) | 2013-09-18 |
| DK1441589T3 (da) | 2012-08-06 |
| LU93314I2 (cg-RX-API-DMAC7.html) | 2019-11-20 |
| CY2016044I1 (el) | 2017-07-12 |
| JP2011068675A (ja) | 2011-04-07 |
| KR20050044365A (ko) | 2005-05-12 |
| KR100913714B1 (ko) | 2009-08-24 |
| NZ532896A (en) | 2007-08-31 |
| EP1441589B1 (en) | 2012-05-09 |
| ES2392073T3 (es) | 2012-12-04 |
| US20030138417A1 (en) | 2003-07-24 |
| CA2466034C (en) | 2012-12-18 |
| JP2005508981A (ja) | 2005-04-07 |
| CY2016044I2 (el) | 2017-07-12 |
| WO2003039485A2 (en) | 2003-05-15 |
| US8465739B2 (en) | 2013-06-18 |
| EP1441589A2 (en) | 2004-08-04 |
| IL161677A0 (en) | 2004-09-27 |
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