AU2002310863A1 - Enzymatic process for preparing cephalosporanic acid derivatives using alpha-ketoacid derivatives - Google Patents

Enzymatic process for preparing cephalosporanic acid derivatives using alpha-ketoacid derivatives

Info

Publication number
AU2002310863A1
AU2002310863A1 AU2002310863A AU2002310863A AU2002310863A1 AU 2002310863 A1 AU2002310863 A1 AU 2002310863A1 AU 2002310863 A AU2002310863 A AU 2002310863A AU 2002310863 A AU2002310863 A AU 2002310863A AU 2002310863 A1 AU2002310863 A1 AU 2002310863A1
Authority
AU
Australia
Prior art keywords
derivatives
alpha
ketoacid
cephalosporanic acid
enzymatic process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002310863A
Other languages
English (en)
Inventor
Francisco Garcia-Carmona
Jose Aniceto Lopez-Mas
Alvaro Sanchez-Ferrer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioferma Murcia SA
Original Assignee
Bioferma Murcia SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioferma Murcia SA filed Critical Bioferma Murcia SA
Publication of AU2002310863A1 publication Critical patent/AU2002310863A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
AU2002310863A 2001-04-19 2002-04-18 Enzymatic process for preparing cephalosporanic acid derivatives using alpha-ketoacid derivatives Abandoned AU2002310863A1 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
EP01201426.2 2001-04-19
EP01201426 2001-04-19
EP01201718.2 2001-05-09
EP01201718 2001-05-09
EP01201699.4 2001-05-09
EP01201699 2001-05-09
IE20011025 2001-11-30
IE2001/1025 2001-11-30
IE20011024 2001-11-30
IE2001/1024 2001-11-30
PCT/EP2002/004353 WO2002085914A2 (en) 2001-04-19 2002-04-18 ENZYMATIC PROCESS FOR PREPARING CEPHALOSPORANIC ACID DERIVATIVES USING α-KETOACID DERIVATIVES

Publications (1)

Publication Number Publication Date
AU2002310863A1 true AU2002310863A1 (en) 2002-11-05

Family

ID=27513105

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2002316862A Abandoned AU2002316862A1 (en) 2001-04-19 2002-04-18 Enzymatic process for preparing cephalosporin derivatives
AU2002310863A Abandoned AU2002310863A1 (en) 2001-04-19 2002-04-18 Enzymatic process for preparing cephalosporanic acid derivatives using alpha-ketoacid derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU2002316862A Abandoned AU2002316862A1 (en) 2001-04-19 2002-04-18 Enzymatic process for preparing cephalosporin derivatives

Country Status (7)

Country Link
US (5) US6730497B2 (US20030073156A1-20030417-C00009.png)
EP (2) EP1379531A2 (US20030073156A1-20030417-C00009.png)
JP (2) JP2004537985A (US20030073156A1-20030417-C00009.png)
KR (2) KR20040014498A (US20030073156A1-20030417-C00009.png)
CN (2) CN1531598A (US20030073156A1-20030417-C00009.png)
AU (2) AU2002316862A1 (US20030073156A1-20030417-C00009.png)
WO (2) WO2002085914A2 (US20030073156A1-20030417-C00009.png)

Families Citing this family (14)

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Publication number Priority date Publication date Assignee Title
AU2002316862A1 (en) * 2001-04-19 2002-11-05 Bioferma Murcia, S.A. Enzymatic process for preparing cephalosporin derivatives
ATE302283T1 (de) * 2002-10-31 2005-09-15 Bioferma Murcia S A Einfaches enzymatisches verfahren zur herstellung von cefazolin
KR100650207B1 (ko) 2005-07-29 2006-11-27 종근당바이오 주식회사 글루타릴 7-아미노-3-비닐-세팔로스포란산 유도체와 이의 제조방법
CN103635586A (zh) 2011-06-23 2014-03-12 中化帝斯曼制药有限公司荷兰公司 结晶头孢氧哌唑中间体、其制备方法及其制药用途
PL2723882T3 (pl) 2011-06-23 2020-01-31 Centrient Pharmaceuticals Netherlands B.V. Sposób wytwarzania 3’-tiopodstawionych cefalosporyn z zastosowaniem acylazy penicyliny
CN102605033B (zh) * 2012-01-17 2013-11-27 湖南福来格生物技术有限公司 头孢唑啉中间体tda的制备方法
CN102633813A (zh) * 2012-04-17 2012-08-15 黑龙江豪运精细化工有限公司 一种头孢唑林钠中间体tda的制备方法
CN102627659A (zh) * 2012-04-17 2012-08-08 黑龙江豪运精细化工有限公司 一种头孢哌酮中间体7-tmca的制备方法
CN102659818B (zh) * 2012-04-19 2014-02-19 海南合瑞制药股份有限公司 一种盐酸头孢替安晶体化合物及其制备方法及含该化合物的药物组合物
CN102993214B (zh) * 2012-12-07 2015-01-28 西北大学 一种头孢菌素的脱色方法
CN104230958A (zh) * 2014-08-22 2014-12-24 赵明亮 一种头孢西酮的制备方法
CN106317079B (zh) * 2016-08-19 2018-08-21 上海上药新亚药业有限公司 一种头孢曲松钠的固相合成法
CN107964558B (zh) * 2017-11-07 2021-09-03 河北九派制药股份有限公司 一种盐酸头孢替安杂质脱四氮唑头孢替安的制备方法
CN113929704A (zh) * 2021-11-24 2022-01-14 焦作丽珠合成制药有限公司 一种利用水相法制备7-act的方法

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Also Published As

Publication number Publication date
WO2002085914A3 (en) 2003-02-06
EP1381690A2 (en) 2004-01-21
US20030073156A1 (en) 2003-04-17
US20030104515A1 (en) 2003-06-05
WO2002085914A2 (en) 2002-10-31
US20040181056A1 (en) 2004-09-16
CN1531598A (zh) 2004-09-22
KR20040014498A (ko) 2004-02-14
CN1531539A (zh) 2004-09-22
US6730497B2 (en) 2004-05-04
JP2004538265A (ja) 2004-12-24
WO2002086143A2 (en) 2002-10-31
AU2002316862A1 (en) 2002-11-05
US20040175783A1 (en) 2004-09-09
US6642020B2 (en) 2003-11-04
WO2002086143A3 (en) 2003-01-09
US20040067549A1 (en) 2004-04-08
KR20040014499A (ko) 2004-02-14
EP1379531A2 (en) 2004-01-14
JP2004537985A (ja) 2004-12-24

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase