AU2003269416A1 - An improved process for the preparation of chloro methyl cephem derivatives - Google Patents

An improved process for the preparation of chloro methyl cephem derivatives

Info

Publication number
AU2003269416A1
AU2003269416A1 AU2003269416A AU2003269416A AU2003269416A1 AU 2003269416 A1 AU2003269416 A1 AU 2003269416A1 AU 2003269416 A AU2003269416 A AU 2003269416A AU 2003269416 A AU2003269416 A AU 2003269416A AU 2003269416 A1 AU2003269416 A1 AU 2003269416A1
Authority
AU
Australia
Prior art keywords
preparation
improved process
chloro methyl
cephem derivatives
methyl cephem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003269416A
Inventor
Pandurang Balwant Deshpande
Sanjay Nivrutti Karale
Padmanabhan Ramar
Palanisamy Senthilkumar Udayampalayam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orchid Pharma Ltd
Original Assignee
Orchid Chemicals and Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orchid Chemicals and Pharmaceuticals Ltd filed Critical Orchid Chemicals and Pharmaceuticals Ltd
Publication of AU2003269416A1 publication Critical patent/AU2003269416A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/08—Preparation by forming the ring or condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)
AU2003269416A 2002-11-01 2003-10-23 An improved process for the preparation of chloro methyl cephem derivatives Abandoned AU2003269416A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN808CH2002 2002-11-01
IN808/MAS/2002 2002-11-01
PCT/IB2003/004721 WO2004039813A1 (en) 2002-11-01 2003-10-23 An improved process for the preparation of chloro methyl cephem derivatives

Publications (1)

Publication Number Publication Date
AU2003269416A1 true AU2003269416A1 (en) 2004-05-25

Family

ID=35561711

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003269416A Abandoned AU2003269416A1 (en) 2002-11-01 2003-10-23 An improved process for the preparation of chloro methyl cephem derivatives

Country Status (5)

Country Link
JP (1) JP2006507289A (en)
KR (1) KR20050087791A (en)
CN (1) CN1315841C (en)
AU (1) AU2003269416A1 (en)
WO (1) WO2004039813A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1666483B1 (en) * 2003-09-09 2011-08-17 Nippon Chemical Industrial Company Limited Process for producing 3-chloromethyl-3-cephem derivative
CN101260116A (en) * 2008-04-21 2008-09-10 湖南有色凯铂生物药业有限公司 Method for synthesizing 7-phenylacetamide-3-chloromethyl-4-cephalosporanic acid p-methoxybenzyl ester
CN102344459B (en) * 2011-07-27 2014-08-06 山西新天源医药化工有限公司 Preparation method of cephalosporin intermediate GCLE
CN102643294B (en) * 2012-04-18 2014-11-26 山东普洛得邦医药有限公司 Preparation method of cephalosporin nucleus intermediate

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE35152B1 (en) * 1969-08-26 1975-11-26 Glaxo Lab Ltd Improvements in or relating to cephalosporin compounds
NL7411505A (en) * 1973-09-06 1975-03-10 Rhone Poulenc Sa PROCEDURE FOR THE PREPARATION AND USE OF NEW 7-TRICHLORACETAMIDO-3-DESACETOXY-CEFA-LOSPORANIC ACID PREPARATIONS.
AU498131B2 (en) * 1974-02-26 1979-02-15 Ciba-Geigy Ag Production of cephems by cyclization
JPS6043340B2 (en) * 1981-04-10 1985-09-27 大塚化学薬品株式会社 Chlorinated azetidinone derivatives and their production method
JPS5874689A (en) * 1981-10-29 1983-05-06 Otsuka Chem Co Ltd Preparation of 3-chloromethyl-3-cephem derivative
GB2099817B (en) * 1981-04-10 1985-05-15 Otsuka Kagaku Yakuhin Azetidinone derivatives and process for the preparation of the same
JPS59164771A (en) * 1983-03-10 1984-09-17 Otsuka Chem Co Ltd Preparation of chlorinated azetidinone derivative
JPS60237061A (en) * 1984-05-08 1985-11-25 Otsuka Chem Co Ltd Preparation of azetidinone derivative
JPS60115562A (en) * 1983-11-28 1985-06-22 Otsuka Chem Co Ltd Production of azetidinone derivative
DE3933934A1 (en) * 1989-10-03 1991-04-11 Bayer Ag METHOD FOR PRODUCING 7-AMINO-3 - ((Z) -1-PROPEN-1-YL) -3-CEPHEM-4-CARBONIC ACID
JP3224279B2 (en) * 1992-07-27 2001-10-29 大塚化学株式会社 Method for producing cefm compound
JP4157177B2 (en) * 1997-06-04 2008-09-24 大塚化学ホールディングス株式会社 Method for producing 3-alkenylcephem compound

Also Published As

Publication number Publication date
CN1315841C (en) 2007-05-16
JP2006507289A (en) 2006-03-02
WO2004039813A1 (en) 2004-05-13
KR20050087791A (en) 2005-08-31
CN1708501A (en) 2005-12-14

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase