AU2002215315C1 - Composition for the transdermal delivery of fentanyl - Google Patents
Composition for the transdermal delivery of fentanyl Download PDFInfo
- Publication number
- AU2002215315C1 AU2002215315C1 AU2002215315A AU2002215315A AU2002215315C1 AU 2002215315 C1 AU2002215315 C1 AU 2002215315C1 AU 2002215315 A AU2002215315 A AU 2002215315A AU 2002215315 A AU2002215315 A AU 2002215315A AU 2002215315 C1 AU2002215315 C1 AU 2002215315C1
- Authority
- AU
- Australia
- Prior art keywords
- fentanyl
- composition
- acrylate
- layer
- copolymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229960002428 fentanyl Drugs 0.000 title claims description 180
- 239000000203 mixture Substances 0.000 title claims description 107
- 230000037317 transdermal delivery Effects 0.000 title claims description 28
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- 239000010410 layer Substances 0.000 claims description 93
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- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical group OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 claims description 42
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Classifications
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- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
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- A61K31/33—Heterocyclic compounds
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
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- A61K9/0012—Galenical forms characterised by the site of application
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
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- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Macromonomer-Based Addition Polymer (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2007205756A AU2007205756B2 (en) | 2000-09-29 | 2007-08-10 | Composition for the transdermal delivery of fentanyl |
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| US23697300P | 2000-09-29 | 2000-09-29 | |
| US60/236,973 | 2000-09-29 | ||
| US28401701P | 2001-04-16 | 2001-04-16 | |
| US60/284,017 | 2001-04-16 | ||
| PCT/US2001/031052 WO2002026217A2 (en) | 2000-09-29 | 2001-09-27 | Composition for the transdermal delivery of fentanyl |
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| AU2007205756A Division AU2007205756B2 (en) | 2000-09-29 | 2007-08-10 | Composition for the transdermal delivery of fentanyl |
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| AU2002215315A1 AU2002215315A1 (en) | 2002-06-20 |
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| AU2002215315A Expired AU2002215315C1 (en) | 2000-09-29 | 2001-09-27 | Composition for the transdermal delivery of fentanyl |
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| AU1531502A Pending AU1531502A (en) | 2000-09-29 | 2001-09-27 | Composition for the transdermal delivery of fentanyl |
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| DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| DE10041478A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| EP1318843B1 (en) * | 2000-09-19 | 2013-04-17 | Henkel AG & Co. KGaA | Acryl adhesive useful in transdermal drug delivery systems |
| US20020119187A1 (en) * | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
| EP1875898A3 (en) * | 2001-03-16 | 2008-08-27 | Alza Corporation | Transdermal patch for administering fentanyl |
| US20050208117A1 (en) * | 2001-03-16 | 2005-09-22 | Venkatraman Subramanian S | Transdermal administration of fentanyl and analogs thereof |
| EP1381352B1 (en) * | 2001-03-16 | 2007-06-13 | Alza Corporation | Transdermal patch for administering fentanyl |
| DE10141650C1 (de) * | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| AU2007202273B2 (en) * | 2001-08-24 | 2009-11-05 | Lts Lohmann Therapie - Systeme Ag | Transdermal therapeutic system containing fentanyl or related substance |
| US8440220B2 (en) * | 2002-04-23 | 2013-05-14 | Durect Corporation | Transdermal analgesic systems with reduced abuse potential |
| AR033748A1 (es) | 2002-05-15 | 2004-01-07 | Thalas Group Inc | Un dispositivo para la administracion transdermica de sustancias farmacologicamente activas que comprende dos capas adhesivas superpuestas y un procedimiento para prepararlo |
| MXPA04011759A (es) * | 2002-05-28 | 2005-07-27 | Labtec Gmbh | Emplasto conteniendo fentanilo. |
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