ATE98651T1 - Peptide mit tachykininantagonistischer aktivitaet, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate. - Google Patents

Peptide mit tachykininantagonistischer aktivitaet, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate.

Info

Publication number
ATE98651T1
ATE98651T1 AT90123875T AT90123875T ATE98651T1 AT E98651 T1 ATE98651 T1 AT E98651T1 AT 90123875 T AT90123875 T AT 90123875T AT 90123875 T AT90123875 T AT 90123875T AT E98651 T1 ATE98651 T1 AT E98651T1
Authority
AT
Austria
Prior art keywords
preparation
tachykin
peptides
pharmaceutical preparations
antagonist activity
Prior art date
Application number
AT90123875T
Other languages
English (en)
Inventor
Matsuo Masaaki
Hagiwara Daijiro
Miyake Hiroshi
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of ATE98651T1 publication Critical patent/ATE98651T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Two-Way Televisions, Distribution Of Moving Picture Or The Like (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT90123875T 1989-12-22 1990-12-12 Peptide mit tachykininantagonistischer aktivitaet, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate. ATE98651T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898929070A GB8929070D0 (en) 1989-12-22 1989-12-22 Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same

Publications (1)

Publication Number Publication Date
ATE98651T1 true ATE98651T1 (de) 1994-01-15

Family

ID=10668423

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90123875T ATE98651T1 (de) 1989-12-22 1990-12-12 Peptide mit tachykininantagonistischer aktivitaet, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate.

Country Status (21)

Country Link
US (1) US5468731A (de)
EP (1) EP0443132B1 (de)
JP (1) JP2560919B2 (de)
KR (1) KR0180223B1 (de)
CN (2) CN1034869C (de)
AT (1) ATE98651T1 (de)
AU (1) AU640185B2 (de)
CA (1) CA2032864C (de)
DE (1) DE69005286T2 (de)
DK (1) DK0443132T3 (de)
ES (1) ES2060910T3 (de)
FI (1) FI93548C (de)
GB (1) GB8929070D0 (de)
HK (1) HK18696A (de)
HU (2) HUT56581A (de)
IE (1) IE64570B1 (de)
NO (1) NO177535C (de)
PT (1) PT96324B (de)
RU (1) RU2055078C1 (de)
UA (1) UA27254C2 (de)
ZA (1) ZA909901B (de)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
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US5654400A (en) * 1991-10-04 1997-08-05 Fujisawa Pharmaceutical Co., Ltd. Process for making peptide compounds having tachykinin antagonistic activity
EP0613458B1 (de) * 1991-11-12 1998-01-07 Pfizer Inc. Azyklische ethylendiaminderivate als 'substance p rezeptor' antagonisten
GB9200535D0 (en) * 1992-01-10 1992-02-26 Fujisawa Pharmaceutical Co New compound
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AU677792B2 (en) * 1992-09-03 1997-05-08 Boehringer Ingelheim Kg New aminoacid derivates, process for producing the same and pharmaceutical compositions containing these compounds
DE4243496A1 (de) * 1992-09-03 1994-03-10 Boehringer Ingelheim Kg Neue Dipeptidderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
FR2700472B1 (fr) 1993-01-19 1995-02-17 Rhone Poulenc Rorer Sa Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2.
WO1994020126A1 (en) * 1993-03-03 1994-09-15 Fujisawa Pharmaceutical Co., Ltd. Use of peptides for the manufacture of a medicament
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US5747069A (en) * 1993-08-10 1998-05-05 Fujisawa Pharmaceutical Co., Ltd. Percutaneously absorbable preparation
EP0731712A4 (de) * 1993-10-29 2005-11-09 Univ Boston Physiologisch stabile butlersäurepräparate, und butlersäuresalze und -derivate als antineoplastische wirkstoff
US6403577B1 (en) 1993-11-17 2002-06-11 Eli Lilly And Company Hexamethyleneiminyl tachykinin receptor antagonists
ITFI940009A1 (it) * 1994-01-19 1995-07-19 Menarini Farma Ind Antagonisti delle tachichinine, loro preparazione e formulazioni farmaceutiche che li contengono.
DE69519182T2 (de) * 1994-03-17 2001-05-17 Fujirebio Inc., Tokio/Tokyo Azapeptid-Derivate
FR2719312B1 (fr) * 1994-04-28 1996-06-14 Adir Nouveau pseudopeptides dérivés de neurokinines, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
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FR2728169A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
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DE3913272A1 (de) * 1989-04-22 1990-10-25 Hoechst Ag Dipeptid-derivate mit enzym-inhibitorischer wirkung
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Also Published As

Publication number Publication date
AU640185B2 (en) 1993-08-19
ES2060910T3 (es) 1994-12-01
ZA909901B (en) 1991-10-30
HU908443D0 (en) 1991-07-29
CA2032864A1 (en) 1991-06-23
GB8929070D0 (en) 1990-02-28
EP0443132B1 (de) 1993-12-15
UA27254C2 (uk) 2000-08-15
DE69005286T2 (de) 1994-04-21
HU211558A9 (en) 1995-12-28
FI93548C (fi) 1995-04-25
IE64570B1 (en) 1995-08-23
KR0180223B1 (ko) 1999-04-01
PT96324A (pt) 1991-09-30
IE904581A1 (en) 1991-07-03
PT96324B (pt) 1998-10-30
FI906204A0 (fi) 1990-12-17
FI906204A (fi) 1991-06-23
NO905572L (no) 1991-06-24
CA2032864C (en) 2003-05-06
CN1064080A (zh) 1992-09-02
NO177535B (no) 1995-06-26
CN1159949A (zh) 1997-09-24
CN1034869C (zh) 1997-05-14
DK0443132T3 (da) 1994-01-24
AU6801090A (en) 1991-06-27
EP0443132A1 (de) 1991-08-28
KR910011891A (ko) 1991-08-07
HUT56581A (en) 1991-09-30
RU2055078C1 (ru) 1996-02-27
NO905572D0 (no) 1990-12-21
DE69005286D1 (de) 1994-01-27
US5468731A (en) 1995-11-21
JP2560919B2 (ja) 1996-12-04
JPH04210996A (ja) 1992-08-03
HK18696A (en) 1996-02-09
FI93548B (fi) 1995-01-13
NO177535C (no) 1995-10-04

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