ATE474058T1 - Lentivirale vektoren zur behandlung neurodegenerativer krankheiten - Google Patents
Lentivirale vektoren zur behandlung neurodegenerativer krankheitenInfo
- Publication number
- ATE474058T1 ATE474058T1 AT01972317T AT01972317T ATE474058T1 AT E474058 T1 ATE474058 T1 AT E474058T1 AT 01972317 T AT01972317 T AT 01972317T AT 01972317 T AT01972317 T AT 01972317T AT E474058 T1 ATE474058 T1 AT E474058T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- neurodegenerative diseases
- lentiviral vectors
- vector genome
- genomes
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/48—Vector systems having a special element relevant for transcription regulating transport or export of RNA, e.g. RRE, PRE, WPRE, CTE
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
- C12N2840/206—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES having multiple IRES
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Plant Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Molds, Cores, And Manufacturing Methods Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0024550.6A GB0024550D0 (de) | 2000-10-06 | 2000-10-06 | |
PCT/GB2001/004433 WO2002029065A2 (en) | 2000-10-06 | 2001-10-05 | Retroviral vectors containing internal ribosomal entry sites |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE474058T1 true ATE474058T1 (de) | 2010-07-15 |
Family
ID=9900826
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01972317T ATE474058T1 (de) | 2000-10-06 | 2001-10-05 | Lentivirale vektoren zur behandlung neurodegenerativer krankheiten |
Country Status (13)
Country | Link |
---|---|
US (3) | US7259015B2 (de) |
EP (2) | EP1337655B1 (de) |
JP (1) | JP4224295B2 (de) |
AT (1) | ATE474058T1 (de) |
AU (1) | AU2001292093A1 (de) |
CA (1) | CA2424738A1 (de) |
CY (1) | CY1110817T1 (de) |
DE (1) | DE60142576D1 (de) |
DK (1) | DK1337655T3 (de) |
ES (1) | ES2348277T3 (de) |
GB (1) | GB0024550D0 (de) |
PT (1) | PT1337655E (de) |
WO (1) | WO2002029065A2 (de) |
Families Citing this family (116)
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2000
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2001
- 2001-10-05 WO PCT/GB2001/004433 patent/WO2002029065A2/en active Application Filing
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- 2001-10-05 ES ES01972317T patent/ES2348277T3/es not_active Expired - Lifetime
- 2001-10-05 EP EP01972317A patent/EP1337655B1/de not_active Expired - Lifetime
- 2001-10-05 PT PT01972317T patent/PT1337655E/pt unknown
- 2001-10-05 EP EP09014156A patent/EP2180057A1/de not_active Withdrawn
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US20070025970A1 (en) | 2007-02-01 |
WO2002029065A3 (en) | 2002-12-27 |
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WO2002029065A2 (en) | 2002-04-11 |
US20040013648A1 (en) | 2004-01-22 |
EP1337655A2 (de) | 2003-08-27 |
CA2424738A1 (en) | 2002-04-11 |
AU2001292093A1 (en) | 2002-04-15 |
US7259015B2 (en) | 2007-08-21 |
CY1110817T1 (el) | 2015-06-10 |
DK1337655T3 (da) | 2010-09-20 |
DE60142576D1 (de) | 2010-08-26 |
EP1337655B1 (de) | 2010-07-14 |
ES2348277T3 (es) | 2010-12-02 |
GB0024550D0 (de) | 2000-11-22 |
PT1337655E (pt) | 2010-08-25 |
EP2180057A1 (de) | 2010-04-28 |
JP2004520016A (ja) | 2004-07-08 |
US20090111106A1 (en) | 2009-04-30 |
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