ATE469656T1 - Verfahren und reagentien zur diagnose von hantavirusinfektionen - Google Patents

Verfahren und reagentien zur diagnose von hantavirusinfektionen

Info

Publication number
ATE469656T1
ATE469656T1 AT05856748T AT05856748T ATE469656T1 AT E469656 T1 ATE469656 T1 AT E469656T1 AT 05856748 T AT05856748 T AT 05856748T AT 05856748 T AT05856748 T AT 05856748T AT E469656 T1 ATE469656 T1 AT E469656T1
Authority
AT
Austria
Prior art keywords
hantavirus
methods
diagnosing
reagents
antigens
Prior art date
Application number
AT05856748T
Other languages
English (en)
Inventor
Steve H Nguyen
Sergio Pichuantes
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of ATE469656T1 publication Critical patent/ATE469656T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/175—Bunyaviridae, e.g. California encephalitis virus, Rift valley fever virus, Hantaan virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/12011—Bunyaviridae
    • C12N2760/12111—Hantavirus, e.g. Hantaan virus
    • C12N2760/12122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT05856748T 2004-06-18 2005-05-24 Verfahren und reagentien zur diagnose von hantavirusinfektionen ATE469656T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58102704P 2004-06-18 2004-06-18
PCT/US2005/018066 WO2006088478A2 (en) 2004-06-18 2005-05-24 Methods and reagents for diagnosing hantavirus infection

Publications (1)

Publication Number Publication Date
ATE469656T1 true ATE469656T1 (de) 2010-06-15

Family

ID=36916873

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05856748T ATE469656T1 (de) 2004-06-18 2005-05-24 Verfahren und reagentien zur diagnose von hantavirusinfektionen

Country Status (9)

Country Link
US (3) US7771730B2 (de)
EP (1) EP1778880B1 (de)
JP (2) JP4813471B2 (de)
KR (1) KR20070026802A (de)
CN (1) CN101163498B (de)
AT (1) ATE469656T1 (de)
DE (1) DE602005021644D1 (de)
ES (1) ES2344150T3 (de)
WO (1) WO2006088478A2 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012083475A1 (es) * 2010-12-20 2012-06-28 Universidad De Desarollo Anticuerpo policlonal neutralizante contra hantavirus andes, procedimiento de producción y composiciones farmacéuticas
BR112013021526B1 (pt) 2011-02-25 2021-09-21 Chugai Seiyaku Kabushiki Kaisha Polipeptídio variante, métodos para manter ou diminuir as atividades de ligação a fcgriia (tipo r) e fcgriia (tipo h) e aumentar a atividade de ligação a fcgriib de um polipeptídio e para a supressão da produção de um anticorpo contra um polipeptídio compreendendo a região fc do anticorpo, métodos para a produção do referido polipeptídio com atividades de ligação mantidas ou diminuídas e aumentada e para a produção suprimida de um anticorpo, composição farmacêutica e uso de um polipeptídio
JP6322411B2 (ja) 2011-09-30 2018-05-09 中外製薬株式会社 複数の生理活性を有する抗原の消失を促進する抗原結合分子
CN102399265B (zh) * 2011-10-28 2014-06-25 中国人民解放军第四军医大学 Htnv-np 特异性的ctl 表位肽及其应用
RU2590606C2 (ru) * 2012-04-12 2016-07-10 Федеральное государственное бюджетное учреждение "Институт полиомиелита и вирусных энцефалитов им. М.П. Чумакова РАМН" Способ получения тест-системы "ханта-n" для определения специфической активности вакцины против геморрагической лихорадки с почечным синдромом
CN102731617B (zh) * 2012-05-05 2013-11-27 中国人民解放军第四军医大学 汉滩病毒糖蛋白特异性t细胞表位肽及其应用
RU2484478C1 (ru) * 2012-05-11 2013-06-10 Государственное бюджетное образовательное учреждение дополнительного профессионального образования "Казанская государственная медицинская академия" Министерства здравоохранения и социального развития Российской Федерации Способ обнаружения антител к хантавирусу при геморрагической лихорадке с почечным синдромом и прогнозирование тяжелых форм заболевания
ES2856272T3 (es) * 2012-05-30 2021-09-27 Chugai Pharmaceutical Co Ltd Molécula de unión a antígenos para eliminar antígenos agregados
CN102731623B (zh) * 2012-06-08 2013-09-18 中国人民解放军第四军医大学 鼠源性单克隆抗体3d8识别的汉滩病毒糖蛋白中和表位肽及应用
NL2009515C2 (en) * 2012-09-25 2014-03-27 Europ Intelligence B V Mooring device for mooring a ship.
AU2014250434B2 (en) 2013-04-02 2019-08-08 Chugai Seiyaku Kabushiki Kaisha Fc region variant
RU2565543C2 (ru) * 2013-04-10 2015-10-20 Федеральное государственное бюджетное научное учреждение "Институт полиомиелита и вирусных энцефалитов им М.П. Чумакова " Способ получения иммуноферментной тест-системы для определения эпитопов оболочечного белка вируса пуумала протективной направленности в вакцинных препаратах против геморрагической лихорадки с почечным синдромом
US20140378329A1 (en) * 2013-06-24 2014-12-25 Idexx Laboratories, Inc. Animal Colony Monitoring Using Fecal Samples
CN106046125B (zh) * 2016-06-30 2020-04-24 中国人民解放军第四军医大学 Htnv gp上的ctl表位肽及其筛选方法和应用
KR102013954B1 (ko) * 2016-12-26 2019-08-23 주식회사 이뮨메드 서울바이러스와 푸말라바이러스 유래의 재조합 뉴클레오캡시드 단백질 및 한탄바이러스 유래의 재조합 당단백질을 포함하는 신증후군출혈열 진단용 조성물 및 이를 포함하는 진단 키트
CN107383176A (zh) * 2017-05-10 2017-11-24 于学杰 用于对汉滩病毒和汉城病毒引起的肾综合征出血热分型的多肽
CN110548136A (zh) * 2018-05-30 2019-12-10 王美亮 汉坦病毒长肽疫苗
CN109852588B (zh) * 2018-12-24 2023-03-07 中国水产科学研究院珠江水产研究所 一种抗罗非鱼免疫球蛋白IgM的单克隆抗体及其细胞株和应用
CN110042173A (zh) * 2019-02-28 2019-07-23 中国科学院广州生物医药与健康研究院 一种同时检测四种出血热病毒的纳米金生物传感器及检测方法
KR102089268B1 (ko) * 2019-10-02 2020-03-16 대한민국 한탄바이러스 절단형 뉴클레오캡시드 단백질을 이용한 한탄바이러스 검출 방법
CN111333705A (zh) * 2019-12-06 2020-06-26 中国人民解放军第四军医大学 影响HTNV Gn胞质尾区的出胞表位序列的筛选及鉴定方法
CN114478719A (zh) * 2022-02-11 2022-05-13 中国人民解放军空军军医大学 一组汉坦病毒包膜糖蛋白的优势表位肽、其编码基因及应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4714556A (en) * 1981-06-29 1987-12-22 Ambrus Clara M Blood purification
US5298423A (en) * 1987-11-25 1994-03-29 The United States Of America As Represented By The Secretary Of The Army Nucleotide sequences encoding the expression of a Hantaan virus nucleocapsid protein and G1 and G2 glycoproteins
JP2664471B2 (ja) * 1989-04-26 1997-10-15 鎬汪 李 腎症候性出血熱の診断用試薬
AU7179094A (en) * 1993-06-24 1995-01-17 United States Of America, As Represented By The Secretary, Department Of Health And Human Services Nucleic acids of a novel hantavirus and reagents for detection and prevention of infection
US5837441A (en) * 1993-08-25 1998-11-17 University Of New Mexico Hantavirus-associated respiratory distress virus antigens
US5853980A (en) * 1995-02-17 1998-12-29 The United States Of America As Represented By The Department Of Health And Human Services Black creek canal hantavirus and related methods
JPH10253634A (ja) * 1997-03-10 1998-09-25 Denki Kagaku Kogyo Kk クラミジア・トラコマティス抗体測定方法及び抗体測定試薬
US6136250A (en) * 1998-01-30 2000-10-24 Comair Rotron, Inc. Apparatus and method of encapsulating motors
US7217812B2 (en) * 1999-01-29 2007-05-15 United States Of America As Represented By The Secretary Of The Army Extraneous DNA sequence that facilitates hantavirus gene expression
FR2794865B1 (fr) * 1999-06-09 2003-04-18 Pasteur Institut Methode de detection precoce des flavivirus et ses applications

Also Published As

Publication number Publication date
JP4813471B2 (ja) 2011-11-09
US20110053140A1 (en) 2011-03-03
WO2006088478A3 (en) 2007-07-05
JP2008503720A (ja) 2008-02-07
EP1778880A2 (de) 2007-05-02
DE602005021644D1 (de) 2010-07-15
KR20070026802A (ko) 2007-03-08
CN101163498A (zh) 2008-04-16
US7771730B2 (en) 2010-08-10
WO2006088478A9 (en) 2007-03-08
US20130085264A1 (en) 2013-04-04
WO2006088478A2 (en) 2006-08-24
EP1778880A4 (de) 2008-05-07
JP2011191322A (ja) 2011-09-29
ES2344150T3 (es) 2010-08-19
US20080108051A1 (en) 2008-05-08
CN101163498B (zh) 2011-10-05
EP1778880B1 (de) 2010-06-02

Similar Documents

Publication Publication Date Title
ATE469656T1 (de) Verfahren und reagentien zur diagnose von hantavirusinfektionen
Paik et al. Study of tofacitinib in refractory dermatomyositis: an open‐label pilot study of ten patients
DE602006012033D1 (de) Verfahren zur messung immunsuppressiver tacrolimus-, sirolimus- und cyclosporin-a-komplexe in einer blutprobe
WO2016092096A1 (en) Anti-carbapenemase antibodies and uses thereof
ATE556717T1 (de) Neutralisierung monoklonaler antikörper gegen mit schwerem akutem respirationssyndrom assoziiertem coronavirus
DK1351707T3 (da) Fremgangsmåder til behandling af autoimmunsygdomme hos et individ og in vitro-diagnostiske analyser
ATE557101T1 (de) Verfahren und zusammensetzungen zur bestimmung eines transplantationstoleranten phänotyps in einem individuum
ATE503846T1 (de) Verfahren zur diagnose eines ovarialkarzinoms
DE60331677D1 (de) Kit zur untersuchung von menschlichem niedermolekulargewicht cd14 und antikörper
PH12020551371A1 (en) Assays to detect neurodegeneration
da Silva-Etto et al. Evaluation of diagnostic accuracy of two rapid stool antigen tests using an immunochromatographic assay to detect Helicobacter pylori
Metanat et al. Acute Q fever among febrile patients in Zahedan, southeastern Iran
DE60325382D1 (de) Verfahren zur diagnose von gebärmutterhalskrebs
EA201491411A1 (ru) Растворимый manf при поражениях бета-клеток поджелудочной железы
DE602005013430D1 (de) Verwendung von asc als marker für kolorektalkarzinome
DE602005023329D1 (de) VERFAHREN ZUR DIAGNOSE NICHT-KLEINZELLIGER LUNGENKARZINOME ÜBER DIE tRNA-DIHYDROURIDIN-SYNTHASEAKTIVITÄT VON URLC8
WO2017125892A3 (es) Anticuerpos monoclonales específicos para el antígeno piii de adenovirus humano (adv), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnóstico de la infección causada por adv
Alvarez et al. The efficacy of ELISA commercial kits for the screening of equine infectious anemia virus infection
WO2022011110A3 (en) Compositions and methods for the diagnosis and treatment of sars-cov-2 virus infection
DE602006003903D1 (de) In-vitro-diagnoseverfahren und kit für eine schwarzschimmel-infektion
ATE472611T1 (de) Verfahren zur diagnose von sepsis durch analyse von cytokine mrna expression
World Health Organization WHO public health research agenda for influenza: optimizing treatment of patients
ATE557277T1 (de) Verfahren zur diagnose von endometriose mittels tfpi-2 protein
DE602005014659D1 (de) Auf immunreaktion gegen boris basierendes verfahren für den nachweis von krebs
ATE461452T1 (de) Verfahren zum nachweis von menschlichem parvovirus-antigen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties