ATE557101T1 - Verfahren und zusammensetzungen zur bestimmung eines transplantationstoleranten phänotyps in einem individuum - Google Patents
Verfahren und zusammensetzungen zur bestimmung eines transplantationstoleranten phänotyps in einem individuumInfo
- Publication number
- ATE557101T1 ATE557101T1 AT05723099T AT05723099T ATE557101T1 AT E557101 T1 ATE557101 T1 AT E557101T1 AT 05723099 T AT05723099 T AT 05723099T AT 05723099 T AT05723099 T AT 05723099T AT E557101 T1 ATE557101 T1 AT E557101T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- compositions
- subject
- tolerant phenotype
- transplantation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53843904P | 2004-01-21 | 2004-01-21 | |
US57147104P | 2004-05-14 | 2004-05-14 | |
PCT/US2005/004799 WO2005070086A2 (en) | 2004-01-21 | 2005-01-20 | Methods and compositions for determining a graft tolerant phenotype in a subject |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE557101T1 true ATE557101T1 (de) | 2012-05-15 |
Family
ID=34811352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05723099T ATE557101T1 (de) | 2004-01-21 | 2005-01-20 | Verfahren und zusammensetzungen zur bestimmung eines transplantationstoleranten phänotyps in einem individuum |
Country Status (5)
Country | Link |
---|---|
US (2) | US8932808B1 (de) |
EP (1) | EP1718768B1 (de) |
AT (1) | ATE557101T1 (de) |
CA (2) | CA2553551C (de) |
WO (1) | WO2005070086A2 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE46843E1 (en) | 2005-03-14 | 2018-05-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for evaluating graft survival in a solid organ transplant recipient |
EP2604703B1 (de) | 2005-03-14 | 2017-02-01 | The Board of Trustees of the Leland Stanford Junior University | Verfahren zur Bewertung der Haltbarkeit eines Pfropfs im Körper eines Empfängers fester Organtransplantate |
EP2029769A1 (de) | 2006-05-25 | 2009-03-04 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Verfahren zur diagnose und behandlung von transplantatabstossung und entzündungsleiden |
US20080233573A1 (en) * | 2006-08-28 | 2008-09-25 | Kathleen Storm | Gene expression profiling for identification, monitoring and treatment of transplant rejection |
US20080131441A1 (en) * | 2006-09-26 | 2008-06-05 | Manikkam Suthanthiran | Methods of Using FOXP3 Levels to Predict the Outcome of Organs Undergoing Acute Rejection |
EP1990425A1 (de) * | 2007-05-10 | 2008-11-12 | Tcland R | Diagnose von Immuntransplantatstoleranz |
EP2088205A1 (de) | 2008-02-11 | 2009-08-12 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | PSMB10: Diagnosemarker und therapeutisches Target für chronische Abstoßung |
EP2631301B1 (de) | 2008-08-18 | 2017-10-11 | The Board of Trustees of the Leland Stanford Junior University | Verfahren zur Bestimmung eines transplantattoleranten Phänotyps bei einer Person |
EP2368113A1 (de) * | 2008-12-19 | 2011-09-28 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Biomarker zur diagnose des nieren-allotransplantat- und nierenstatus |
ES2492498T3 (es) * | 2009-01-15 | 2014-09-09 | The Board Of Trustees Of The Leland Stanford Junior University | Panel de biomarcadores para el diagnóstico y la predicción de rechazo de injerto |
US9290813B2 (en) | 2009-12-02 | 2016-03-22 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarkers for determining an allograft tolerant phenotype |
US9535075B2 (en) | 2010-03-25 | 2017-01-03 | The Board Of Trustees Of The Leland Stanford Junior University | Protein and gene biomarkers for rejection of organ transplants |
US8962261B2 (en) | 2011-04-06 | 2015-02-24 | The Board Of Trustees Of The Leland Stanford Junior University | Autoantibody biomarkers for IGA nephropathy |
WO2014036444A1 (en) * | 2012-08-30 | 2014-03-06 | Abbott Laboratories | Prame detection assays |
JP2017530356A (ja) | 2014-09-26 | 2017-10-12 | ソマロジック, インコーポレイテッドSomaLogic, Inc. | 心血管系のリスクイベントの予測及びその使用 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5994076A (en) | 1997-05-21 | 1999-11-30 | Clontech Laboratories, Inc. | Methods of assaying differential expression |
US20030104371A1 (en) | 1997-09-24 | 2003-06-05 | Strom Terry B. | Methods of evaluating transplant rejection |
US6607879B1 (en) * | 1998-02-09 | 2003-08-19 | Incyte Corporation | Compositions for the detection of blood cell and immunological response gene expression |
US6429024B1 (en) | 1998-03-31 | 2002-08-06 | Asahi Kasei Kabushiki Kaisha | Test method for IgA nephropathy |
WO2002092124A1 (en) | 2001-05-11 | 2002-11-21 | Wyeth | Methods for diagnosing and treating ischemia and reperfusion injury and compositions thereof |
US7026121B1 (en) | 2001-06-08 | 2006-04-11 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
US7235358B2 (en) | 2001-06-08 | 2007-06-26 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
US7687530B2 (en) | 2002-11-21 | 2010-03-30 | Genzyme Corporation | Inhibition of chronic tissue transplant rejection |
CA2516013C (en) | 2003-02-14 | 2014-05-13 | Beth Israel Deaconess Medical Center, Inc. | Predicting graft rejection |
US7892745B2 (en) | 2003-04-24 | 2011-02-22 | Xdx, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
CA2529759A1 (en) | 2003-06-20 | 2005-10-13 | University Of Florida | Biomarkers for differentiating between type 2 and type 2 diabetes |
US20070111210A1 (en) | 2003-12-03 | 2007-05-17 | Marc Bigaud | Biomarkers for graft rejection |
EP1734952A1 (de) | 2004-04-08 | 2006-12-27 | Novartis AG | Proteinkinase-c-hemmer zur behandlung von autoimmunerkrankungen und transplantat-abstossung |
US7820382B2 (en) | 2004-08-03 | 2010-10-26 | Bauer A Robert | Method for the early detection of breast cancer, lung cancer, pancreatic cancer and colon polyps, growths and cancers as well as other gastrointestinal disease conditions and the preoperative and postoperative monitoring of transplanted organs from the donor and in the recipient and their associated conditions related and unrelated to the organ transplantation |
EP2604703B1 (de) * | 2005-03-14 | 2017-02-01 | The Board of Trustees of the Leland Stanford Junior University | Verfahren zur Bewertung der Haltbarkeit eines Pfropfs im Körper eines Empfängers fester Organtransplantate |
US7666596B2 (en) | 2005-05-23 | 2010-02-23 | University Of Alberta | Tissue rejection |
EP1731620A1 (de) | 2005-06-07 | 2006-12-13 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Methode zur Diagnose von Immun-Transplantatstoleranz |
US8278038B2 (en) | 2005-06-08 | 2012-10-02 | Millennium Pharmaceuticals, Inc. | Methods for the identification, assessment, and treatment of patients with cancer therapy |
WO2007050588A2 (en) | 2005-10-25 | 2007-05-03 | Renovar Incorporated | Systems and methods for characterizing conditions of organs for transplantation |
BRPI0706967A2 (pt) | 2006-02-06 | 2011-04-12 | Rappaport Family Inst For Res | método e kit para diagnosticar dmt1 |
GB0605217D0 (en) | 2006-03-15 | 2006-04-26 | Novartis Ag | Method and compositions for assessing acute rejection |
GB0607943D0 (en) | 2006-04-21 | 2006-05-31 | Novartis Ag | Biomarkers for chronic transplant dysfunction |
JP5171812B2 (ja) | 2006-04-27 | 2013-03-27 | ユニベルシテ ドゥ モントリオール | 移植片対宿主病のリスクの評価および低減 |
WO2008084331A2 (en) | 2006-06-21 | 2008-07-17 | Hopitaux Universitaires De Geneve | Biomarkers for renal disorders |
WO2008009132A1 (en) | 2006-07-21 | 2008-01-24 | The Governors Of The University Of Alberta | Tissue rejection |
US20080233573A1 (en) | 2006-08-28 | 2008-09-25 | Kathleen Storm | Gene expression profiling for identification, monitoring and treatment of transplant rejection |
WO2009143624A1 (en) | 2008-05-30 | 2009-12-03 | The University Of British Columbia | Methods of diagnosing rejection of a kidney allograft using genomic or proteomic expression profiling |
US8426142B2 (en) | 2008-06-02 | 2013-04-23 | Eisai R&D Management Co., Ltd. | IgA nephropathy testing method and test kit |
EP2631301B1 (de) | 2008-08-18 | 2017-10-11 | The Board of Trustees of the Leland Stanford Junior University | Verfahren zur Bestimmung eines transplantattoleranten Phänotyps bei einer Person |
KR100928403B1 (ko) | 2008-10-01 | 2009-11-26 | 경북대학교 산학협력단 | 티지비엠 신증의 진단용 조성물 및 키트 |
WO2011142901A1 (en) | 2010-05-13 | 2011-11-17 | University Of Medicine And Dentistry Of New Jersey | Diagnostic biomarker profiles for the detection and diagnosis of alzheimer's disease |
-
2005
- 2005-01-20 US US10/585,610 patent/US8932808B1/en active Active
- 2005-01-20 AT AT05723099T patent/ATE557101T1/de active
- 2005-01-20 WO PCT/US2005/004799 patent/WO2005070086A2/en active Application Filing
- 2005-01-20 CA CA2553551A patent/CA2553551C/en not_active Expired - Fee Related
- 2005-01-20 CA CA2957704A patent/CA2957704A1/en not_active Abandoned
- 2005-01-20 EP EP05723099A patent/EP1718768B1/de not_active Not-in-force
-
2014
- 2014-02-27 US US14/192,696 patent/US20140206566A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2005070086A3 (en) | 2006-09-14 |
CA2553551A1 (en) | 2005-08-04 |
US20140206566A1 (en) | 2014-07-24 |
CA2553551C (en) | 2020-12-15 |
WO2005070086A2 (en) | 2005-08-04 |
CA2957704A1 (en) | 2005-08-04 |
EP1718768A2 (de) | 2006-11-08 |
EP1718768A4 (de) | 2007-10-17 |
EP1718768B1 (de) | 2012-05-09 |
US8932808B1 (en) | 2015-01-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE557101T1 (de) | Verfahren und zusammensetzungen zur bestimmung eines transplantationstoleranten phänotyps in einem individuum | |
Miao et al. | ImmuCellAI: a unique method for comprehensive T‐cell subsets abundance prediction and its application in cancer immunotherapy | |
Corbin et al. | Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity | |
NO20074389L (no) | Bestemmelse av respondere til kjemoterapi | |
DE602005013957D1 (de) | Verfahren zur durchführung von vollbluttests | |
WO2006099421A3 (en) | Methods and compositions for evaluating graft survival in a solid organ transplant recipient | |
MX2009004463A (es) | Ensayo para anticuerpos de troponina cardiaca. | |
ATE469656T1 (de) | Verfahren und reagentien zur diagnose von hantavirusinfektionen | |
ATE503846T1 (de) | Verfahren zur diagnose eines ovarialkarzinoms | |
ATE408829T1 (de) | Verfahren und assaykits zum nachweis mononuklearer zellphänotypen | |
ATE456801T1 (de) | Verfahren zur messung immunsuppressiver tacrolimus-, sirolimus- und cyclosporin-a- komplexe in einer blutprobe | |
Zhong et al. | Correlation between imatinib trough concentration and efficacy in Chinese chronic myelocytic leukemia patients | |
Park et al. | Telomere length and somatic mutations in correlation with response to immunosuppressive treatment in aplastic anaemia | |
WO2011133770A3 (en) | Salivary protein markers for detection of breast cancer | |
Jo et al. | Impact of mouse contamination in genomic profiling of patient-derived models and best practice for robust analysis | |
Perez‐Lamarque et al. | Analysing diversification dynamics using barcoding data: the case of an obligate mycorrhizal symbiont | |
WO2005121366A8 (ja) | 遺伝子マーカー及びその利用 | |
MX2009006744A (es) | Panel de padecimiento cardiovascular autoinmune y metodos de utilizacion del mismo. | |
Ilhan et al. | Leukemic stem cells shall be searched in the bone marrow before “tyrosine kinase inhibitor‐discontinuation” in chronic myeloid leukemia | |
DE602005011203D1 (de) | Verfahren und Zusammensetzungen zur Charakterisierung eines Redox-Reagenz-System Enzyms | |
Piano Mortari et al. | Functional CVIDs phenotype clusters identified by the integration of immune parameters after BNT162b2 boosters | |
WO2007078835A3 (en) | Biomarker isolation and use thereof to characterize physiological state | |
WO2008147206A3 (en) | Means and methods for classifying samples of multiple sclerosis patients | |
Lovell et al. | Cryptic speciation in the Warbling Vireo (Vireo gilvus) | |
GB0617116D0 (en) | Method of diagnosis |