ATE472611T1 - Verfahren zur diagnose von sepsis durch analyse von cytokine mrna expression - Google Patents

Verfahren zur diagnose von sepsis durch analyse von cytokine mrna expression

Info

Publication number
ATE472611T1
ATE472611T1 AT06809745T AT06809745T ATE472611T1 AT E472611 T1 ATE472611 T1 AT E472611T1 AT 06809745 T AT06809745 T AT 06809745T AT 06809745 T AT06809745 T AT 06809745T AT E472611 T1 ATE472611 T1 AT E472611T1
Authority
AT
Austria
Prior art keywords
sepsis
diagnosis
mrna expression
cytokine mrna
analyzing cytokine
Prior art date
Application number
AT06809745T
Other languages
English (en)
Inventor
Thomas Ryan
Dermot Kelleher
Owen Mcmanus
Michael O'dwyer
Patrick Stordeur
Original Assignee
Trinity College Dublin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trinity College Dublin filed Critical Trinity College Dublin
Application granted granted Critical
Publication of ATE472611T1 publication Critical patent/ATE472611T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT06809745T 2005-11-25 2006-11-27 Verfahren zur diagnose von sepsis durch analyse von cytokine mrna expression ATE472611T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE20050783 2005-11-25
PCT/IE2006/000133 WO2007060647A2 (en) 2005-11-25 2006-11-27 A method for detecting or monitoring sepsis by analysing cytokine mrna expression levels

Publications (1)

Publication Number Publication Date
ATE472611T1 true ATE472611T1 (de) 2010-07-15

Family

ID=37682651

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06809745T ATE472611T1 (de) 2005-11-25 2006-11-27 Verfahren zur diagnose von sepsis durch analyse von cytokine mrna expression

Country Status (6)

Country Link
US (2) US20090297474A1 (de)
EP (1) EP1951899B1 (de)
AT (1) ATE472611T1 (de)
DE (1) DE602006015221D1 (de)
ES (1) ES2349691T3 (de)
WO (1) WO2007060647A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2740191A1 (en) * 2008-10-09 2010-04-15 Thomas Ryan A method of estimating risk of severe sepsis in an individual with infection
EP2893354B1 (de) * 2012-08-31 2018-10-10 Children's Hospital Medical Center Verwendung von interleukin-27 als diagnostischer biomarker für bakterielle infektionen bei patienten
WO2014201516A2 (en) 2013-06-20 2014-12-24 Immunexpress Pty Ltd Biomarker identification
US10815526B2 (en) 2013-11-25 2020-10-27 Children's Hospital Medical Center Temporal pediatric sepsis biomarker risk model
AU2015213486B2 (en) * 2014-02-06 2020-10-22 Immunexpress Pty Ltd Biomarker signature method, and apparatus and kits therefor
CN115161389A (zh) * 2016-06-26 2022-10-11 斯坦福大学托管董事会 用于危重患者的死亡预后的生物标志物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0928293A1 (de) * 1996-06-20 1999-07-14 Koster, Henk W. Von il-6 und il-6 rezeptor abgeleitete peptide mit il-6 antagonistischer oder agonistischer aktivität
DE10155600B4 (de) * 2001-11-09 2009-08-27 Oligene Gmbh Nukleinsäure-Array
WO2004043236A2 (en) * 2002-11-12 2004-05-27 Becton, Dickinson And Company Diagnosis of sepsis or sirs using biomarker profiles
CA2505902A1 (en) * 2002-11-12 2004-05-27 Becton, Dickinson And Company Diagnosis of sepsis or sirs using biomarker profiles
FR2855832B1 (fr) * 2003-06-03 2007-09-14 Biomerieux Sa Procede de diagnostic et/ou de pronostic d'un syndrome septique
GB0426982D0 (en) * 2004-12-09 2005-01-12 Secr Defence Early detection of sepsis

Also Published As

Publication number Publication date
US20130040299A1 (en) 2013-02-14
DE602006015221D1 (de) 2010-08-12
ES2349691T3 (es) 2011-01-10
EP1951899A2 (de) 2008-08-06
US20090297474A1 (en) 2009-12-03
WO2007060647A3 (en) 2007-07-19
EP1951899B1 (de) 2010-06-30
WO2007060647A2 (en) 2007-05-31

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