ATE548467T1 - Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zustände - Google Patents

Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zustände

Info

Publication number
ATE548467T1
ATE548467T1 AT06814191T AT06814191T ATE548467T1 AT E548467 T1 ATE548467 T1 AT E548467T1 AT 06814191 T AT06814191 T AT 06814191T AT 06814191 T AT06814191 T AT 06814191T AT E548467 T1 ATE548467 T1 AT E548467T1
Authority
AT
Austria
Prior art keywords
biomarkers
biological conditions
identifying
biomarkers useful
identifying biomarkers
Prior art date
Application number
AT06814191T
Other languages
English (en)
Inventor
James Willey
Erin Crawford
D Anna Mullins
Original Assignee
Univ Toledo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Toledo filed Critical Univ Toledo
Application granted granted Critical
Publication of ATE548467T1 publication Critical patent/ATE548467T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT06814191T 2005-09-02 2006-09-05 Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zustände ATE548467T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US71362905P 2005-09-02 2005-09-02
US71413805P 2005-09-02 2005-09-02
US71362805P 2005-09-02 2005-09-02
PCT/US2006/034594 WO2007028161A2 (en) 2005-09-02 2006-09-05 Methods and compositions for identifying biomarkers useful in diagnosis and/or treatment of biological states

Publications (1)

Publication Number Publication Date
ATE548467T1 true ATE548467T1 (de) 2012-03-15

Family

ID=37809661

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06814191T ATE548467T1 (de) 2005-09-02 2006-09-05 Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zustände

Country Status (7)

Country Link
US (3) US20070092892A1 (de)
EP (2) EP1940860B1 (de)
JP (2) JP2009506778A (de)
AT (1) ATE548467T1 (de)
AU (2) AU2006287191A1 (de)
CA (2) CA2620528A1 (de)
WO (2) WO2007028162A2 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030186246A1 (en) * 2002-03-28 2003-10-02 Willey James C. Multiplex standardized reverse transcriptase-polymerase chain reacton method for assessment of gene expression in small biological samples
JP2006506945A (ja) * 2002-03-28 2006-03-02 メディカル・カレッジ・オブ・オハイオ 遺伝子発現プロフィールを使用する非小細胞肺癌の診断および処置のための方法および組成物
EP1851335B1 (de) * 2005-01-21 2014-11-26 Gene Express, Inc. Zusammensetzungen und verfahren zur verwendung von standardisierten gemischen
EP3211093A1 (de) 2005-04-14 2017-08-30 The Trustees of Boston University Diagnose für lungenerkrankungen mittels klassenvorhersage
US20070092892A1 (en) * 2005-09-02 2007-04-26 Willey James C Methods and compositions for identifying biomarkers useful in diagnosis and/or treatment of biological states
JP2009529329A (ja) 2006-03-09 2009-08-20 トラスティーズ オブ ボストン ユニバーシティ 鼻腔上皮細胞の遺伝子発現プロファイルを用いた、肺疾患のための診断および予後診断の方法
US8765368B2 (en) * 2007-09-17 2014-07-01 The University Of Toledo Cancer risk biomarker
JP2010538680A (ja) 2007-09-19 2010-12-16 ザ トラスティーズ オブ ボストン ユニバーシティー 肺疾患に対する薬剤開発のための新規経路の同定
CA2719805A1 (en) * 2008-03-28 2009-10-01 Trustees Of Boston University Multifactorial methods for detecting lung disorders
US8771947B2 (en) * 2008-03-31 2014-07-08 The University Of Toledo Cancer risk biomarkers
US10236078B2 (en) 2008-11-17 2019-03-19 Veracyte, Inc. Methods for processing or analyzing a sample of thyroid tissue
US8348856B1 (en) 2008-12-16 2013-01-08 Zanetta Malanowska-Stega Simultaneous multiple method out-patient uterus biopsy device and method
US8669057B2 (en) 2009-05-07 2014-03-11 Veracyte, Inc. Methods and compositions for diagnosis of thyroid conditions
US8824769B2 (en) 2009-10-16 2014-09-02 General Electric Company Process and system for analyzing the expression of biomarkers in a cell
US8320655B2 (en) 2009-10-16 2012-11-27 General Electric Company Process and system for analyzing the expression of biomarkers in cells
JP2012193121A (ja) * 2011-03-15 2012-10-11 Kose Corp マトリックスメタロプロテアーゼ活性阻害剤
CN102435734A (zh) * 2011-09-08 2012-05-02 大连医科大学 卵巢癌原发化疗敏感性测评试剂盒及其应用
US9944973B2 (en) 2012-11-26 2018-04-17 The University Of Toledo Methods for standardized sequencing of nucleic acids and uses thereof
WO2014186036A1 (en) 2013-03-14 2014-11-20 Allegro Diagnostics Corp. Methods for evaluating copd status
US11976329B2 (en) 2013-03-15 2024-05-07 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
CN103617256B (zh) * 2013-11-29 2018-01-02 北京诺禾致源科技股份有限公司 待变异检测文件的处理方法及装置
US12297505B2 (en) 2014-07-14 2025-05-13 Veracyte, Inc. Algorithms for disease diagnostics
CN114606309A (zh) 2014-11-05 2022-06-10 威拉赛特公司 使用机器学习和高维转录数据的诊断系统和方法
WO2017043647A1 (ja) * 2015-09-11 2017-03-16 国立研究開発法人理化学研究所 転写因子結合部位特異的なｄｎａ脱メチル化方法
US10927417B2 (en) 2016-07-08 2021-02-23 Trustees Of Boston University Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions
MX2019006793A (es) 2016-12-09 2019-11-18 Zanetta Malanowska Stega Dispositivo, kit y metodos de cepillo para biopsia.

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302509A (en) * 1989-08-14 1994-04-12 Beckman Instruments, Inc. Method for sequencing polynucleotides
WO1991013147A1 (en) * 1990-03-02 1991-09-05 The United States Of America, Represented By The Secretary, United States Department Of Commerce An immortalized human bronchial epithelial cell line
US5876978A (en) * 1993-04-06 1999-03-02 Medical College Of Ohio Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction
US5643765A (en) * 1993-04-06 1997-07-01 University Of Rochester Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction
US5639606A (en) * 1993-04-06 1997-06-17 The University Of Rochester Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction
WO1995024223A1 (en) * 1994-03-08 1995-09-14 Thomas Jefferson University Inhibition of cell proliferation by e2f-1 antisense oligonucleotides
US7625697B2 (en) * 1994-06-17 2009-12-01 The Board Of Trustees Of The Leland Stanford Junior University Methods for constructing subarrays and subarrays made thereby
US5840506A (en) * 1996-06-05 1998-11-24 Thomas Jefferson University Methods for the diagnosis and prognosis of cancer
US6303301B1 (en) * 1997-01-13 2001-10-16 Affymetrix, Inc. Expression monitoring for gene function identification
US7541141B2 (en) * 1997-02-27 2009-06-02 Wisconsin Alumni Research Foundation Method of using estrogen-related receptor alpha (ERRα) status to determine prognosis, treatment strategy and predisposition to breast cancer, and method of using ERRα as a therapeutic target for the treatment of breast cancer
AU1926899A (en) * 1997-12-19 1999-07-12 Affymetrix, Inc. Exploiting genomics in the search for new drugs
US6194038B1 (en) * 1998-03-20 2001-02-27 Applied Materials, Inc. Method for deposition of a conformal layer on a substrate
US6020135A (en) * 1998-03-27 2000-02-01 Affymetrix, Inc. P53-regulated genes
US6821724B1 (en) * 1998-09-17 2004-11-23 Affymetrix, Inc. Methods of genetic analysis using nucleic acid arrays
US6340565B1 (en) * 1998-11-03 2002-01-22 Affymetrix, Inc. Determining signal transduction pathways
US6177248B1 (en) * 1999-02-24 2001-01-23 Affymetrix, Inc. Downstream genes of tumor suppressor WT1
US20030064072A9 (en) * 1999-03-12 2003-04-03 Rosen Craig A. Nucleic acids, proteins and antibodies
US7056661B2 (en) * 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
US6841348B1 (en) * 1999-10-21 2005-01-11 Affymetrix, Inc. Methods for identifying and using maintenance genes
US20020032319A1 (en) * 2000-03-07 2002-03-14 Whitehead Institute For Biomedical Research Human single nucleotide polymorphisms
US20050048480A1 (en) * 2000-07-19 2005-03-03 Yasuhhiro Tsubosa Method of detecting cancer
JP4139085B2 (ja) * 2001-02-15 2008-08-27 三星エスディアイ株式会社 有機ｅｌデバイスおよびこの製造方法
AU2002250285A1 (en) * 2001-03-14 2002-09-24 Medical College Of Ohio Method for quantitative measurement of gene expression for identifying individuals at risk for bronchogenic carcinoma
US7524492B2 (en) * 2001-08-31 2009-04-28 Joslin Diabetes Center, Inc. Insulin related transcription factor and uses thereof
US7295350B2 (en) * 2001-09-10 2007-11-13 Transpacific Ip Ltd Photographic film scanning device
US20030144799A1 (en) * 2001-09-17 2003-07-31 Volker Nowotny Regulatory single nucleotide polymorphisms and methods therefor
EP1444361A4 (de) * 2001-09-28 2006-12-27 Whitehead Biomedical Inst Klassifizierung von lungenkarzinomen mittels genexpressionsanalyse
ATE413469T1 (de) * 2001-11-02 2008-11-15 Hybrizyme Corp Rezeptoreinfang-assay
WO2003067217A2 (en) * 2002-02-08 2003-08-14 Integriderm, Inc. Skin cell biomarkers and methods for identifying biomarkers using nucleic acid microarrays
AU2003225573A1 (en) * 2002-02-13 2003-09-04 The Government Of The United States Of America As Represented By The Secretary, Department Of He Identification of ovarian cancer tumor markers and therapeutic targets
US20030186246A1 (en) * 2002-03-28 2003-10-02 Willey James C. Multiplex standardized reverse transcriptase-polymerase chain reacton method for assessment of gene expression in small biological samples
JP2006506945A (ja) * 2002-03-28 2006-03-02 メディカル・カレッジ・オブ・オハイオ 遺伝子発現プロフィールを使用する非小細胞肺癌の診断および処置のための方法および組成物
US7222140B2 (en) * 2002-08-28 2007-05-22 International Business Machines Corporation Method for improving the recovery time from a lost database in a VTS automation system
US7459273B2 (en) * 2002-10-04 2008-12-02 Affymetrix, Inc. Methods for genotyping selected polymorphism
US20040161779A1 (en) * 2002-11-12 2004-08-19 Affymetrix, Inc. Methods, compositions and computer software products for interrogating sequence variations in functional genomic regions
EP1603514A4 (de) * 2003-01-24 2007-08-22 Bayer Pharmaceuticals Corp Expressionsprofile für dickdarmkrebs und anwendungsverfahren
US20050042654A1 (en) * 2003-06-27 2005-02-24 Affymetrix, Inc. Genotyping methods
NZ544472A (en) * 2003-07-03 2009-04-30 Myriad Genetics Inc Compounds and therapeutical use thereof
US20070037156A1 (en) * 2003-08-11 2007-02-15 Lovelace Respiratory Research Institute Metalloproteinase gene polymorphism in copd
US8304192B2 (en) * 2004-03-05 2012-11-06 University Of Toledo Methods and compositions for assessing nucleic acids and alleles
CA2568238C (en) * 2004-04-12 2013-10-15 Medical College Of Ohio Methods and compositions for assaying analytes
EP1851335B1 (de) * 2005-01-21 2014-11-26 Gene Express, Inc. Zusammensetzungen und verfahren zur verwendung von standardisierten gemischen
US20070092892A1 (en) * 2005-09-02 2007-04-26 Willey James C Methods and compositions for identifying biomarkers useful in diagnosis and/or treatment of biological states

Also Published As

Publication number Publication date
WO2007028161A2 (en) 2007-03-08
WO2007028161A3 (en) 2008-10-16
US20070092892A1 (en) 2007-04-26
US20070092893A1 (en) 2007-04-26
EP1940860A4 (de) 2009-04-22
CA2620521A1 (en) 2007-03-08
US20070092891A1 (en) 2007-04-26
JP2009507229A (ja) 2009-02-19
WO2007028162A2 (en) 2007-03-08
EP1940860A2 (de) 2008-07-09
EP1934377A2 (de) 2008-06-25
WO2007028162A3 (en) 2007-07-05
AU2006287190A1 (en) 2007-03-08
EP1940860B1 (de) 2012-08-08
JP2009506778A (ja) 2009-02-19
EP1934377A4 (de) 2009-04-22
AU2006287191A1 (en) 2007-03-08
CA2620528A1 (en) 2007-03-08
EP1934377B1 (de) 2012-03-07

Similar Documents

Publication Publication Date Title
ATE548467T1 (de) Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zustände
ATE493649T1 (de) Verfahren zur diagnose von polyzystischer nierenkrankheit
ATE522627T1 (de) Verfahren zur herstellung von nukleinsäuresonden
MX2013001042A (es) Biomarcadores de cancer pancreatico y usos de los mismos.
ATE535805T1 (de) Verfahren zur erkennung von autoantikörpern zur diagnostizierung und charakterisierung von erkrankungen
ATE511656T1 (de) Verfahren zur risikobewertung von herzeingriffen auf gdf-15-basis
ATE525482T1 (de) Nanoreporter und verfahren zu deren herstellung und verwendung
ATE521894T1 (de) Verfahren zur beurteilung von kolorektalem krebs anhand einer stuhlprobe durch verwendung einer marker-kombination aus calprotectin und einem hämoglobin/haptoglobin-komplex
GB2478441A (en) Lung cancer biomarkers and uses thereof
ATE515488T1 (de) Click-chemie zur herstellung von reportermolekülen
WO2008091814A3 (en) Assessment of asthma and allergen-dependent gene expression
EP3318643A3 (de) Verfahren und zusammensetzungen zur identifizierung und behandlung von lupus
ATE471512T1 (de) Verwendung des proteins s100a 12 als marker für kolorektalkarzinom
MX2007002908A (es) Sondas inmovilizadas y metodos para detectar proteinas prionicas alteradas conformacionalmente.
ATE550668T1 (de) Verfahren zur identifizierung von patienten mit erhöhtem risiko für ein unerwünschtes herz- kreislauf-ereignis
ATE503846T1 (de) Verfahren zur diagnose eines ovarialkarzinoms
WO2009125936A3 (ko) 다낭성 난소 증후군 진단을 위한 분석방법 및 키트
EA201100253A1 (ru) Глутаминилциклаза в качестве диагностического/прогностического индикатора нейродегенеративных заболеваний
ATE551605T1 (de) Verfahren und vorrichtungen zur erkennung von biofilmen
WO2008107377A3 (en) Combinations of markers for sepsis risk assessment
DE602005013430D1 (de) Verwendung von asc als marker für kolorektalkarzinome
ATE432469T1 (de) Auf immunreaktion gegen boris basierendes verfahren für den nachweis von krebs
GB0802456D0 (en) Diagnostic method
WO2009120802A3 (en) Methods and compositions for identifying biomarkers useful in characterizing biological states
DE602007010939D1 (de) Abcbi-genotypisierung zur vorhersage der mikrotubuli-stabilisatorwirkstoffinduzierten toxizität