ATE470153T1 - Diagnostische verfahren für therapeutische verbindungen sowie verfahren zur überwachung der azathioprin-therapie - Google Patents

Diagnostische verfahren für therapeutische verbindungen sowie verfahren zur überwachung der azathioprin-therapie

Info

Publication number
ATE470153T1
ATE470153T1 AT04819656T AT04819656T ATE470153T1 AT E470153 T1 ATE470153 T1 AT E470153T1 AT 04819656 T AT04819656 T AT 04819656T AT 04819656 T AT04819656 T AT 04819656T AT E470153 T1 ATE470153 T1 AT E470153T1
Authority
AT
Austria
Prior art keywords
methods
azathioprine therapy
therapeutic compounds
individual
monitoring
Prior art date
Application number
AT04819656T
Other languages
English (en)
Inventor
Marcus Neurath
Matthias Schwab
Original Assignee
Bosch Robert Med Forsch Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bosch Robert Med Forsch Gmbh filed Critical Bosch Robert Med Forsch Gmbh
Application granted granted Critical
Publication of ATE470153T1 publication Critical patent/ATE470153T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047Cells of the immune system
    • G01N33/505Cells of the immune system involving T-cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2510/00Detection of programmed cell death, i.e. apoptosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT04819656T 2003-12-05 2004-12-06 Diagnostische verfahren für therapeutische verbindungen sowie verfahren zur überwachung der azathioprin-therapie ATE470153T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52737603P 2003-12-05 2003-12-05
US11/003,306 US7524851B2 (en) 2003-12-05 2004-12-02 Diagnostic methods for therapeutic compounds and methods for monitoring azathioprine therapy
PCT/EP2004/013842 WO2005054850A2 (en) 2003-12-05 2004-12-06 Diagnostic methods for therapeutic compounds and methods for monitoring azathioprine therapy

Publications (1)

Publication Number Publication Date
ATE470153T1 true ATE470153T1 (de) 2010-06-15

Family

ID=34656405

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04819656T ATE470153T1 (de) 2003-12-05 2004-12-06 Diagnostische verfahren für therapeutische verbindungen sowie verfahren zur überwachung der azathioprin-therapie

Country Status (6)

Country Link
US (1) US7524851B2 (de)
EP (1) EP1695092B8 (de)
AT (1) ATE470153T1 (de)
CA (1) CA2551010A1 (de)
DE (1) DE602004027534D1 (de)
WO (1) WO2005054850A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20050391A1 (it) * 2005-07-22 2007-01-23 Giuliani Spa Composti analoghi della 6-tioguanosina trifosfato, loro uso in campo medico e procedimento per la loro preparazione.
US8124764B2 (en) 2008-07-14 2012-02-28 Gilead Sciences, Inc. Fused heterocyclyc inhibitor compounds
CA2729909A1 (en) 2008-07-14 2010-01-21 Gilead Sciences, Inc. Imidazolyl pyrimidine inhibitor compounds
CA2728228A1 (en) 2008-07-14 2010-01-21 Gilead Sciences, Inc. Oxindolyl inhibitor compounds
CA2731323A1 (en) 2008-07-28 2010-02-04 Gilead Sciences, Inc. Cycloalkylidene and heterocycloalkylidene histone deacetylase inhibitor compounds
ES2463826T3 (es) 2009-06-08 2014-05-29 Gilead Sciences, Inc. Compuestos inhibidores de HDAC de cicloalquilcarbamato benzamida anilina
CA2763786C (en) 2009-06-08 2014-09-30 Gilead Sciences, Inc. Alkanoylamino benzamide aniline hdac inihibitor compounds
WO2012048106A2 (en) * 2010-10-06 2012-04-12 Board Of Regents, The University Of Texas System Biomarkers useful to predict mek inhibitor drug efficacy
CN106226414A (zh) * 2016-07-08 2016-12-14 黑龙江东方学院 利用hplc法测定婴幼儿配方奶粉中核苷酸的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6355623B2 (en) 1998-09-24 2002-03-12 Hopital-Sainte-Justine Method of treating IBD/Crohn's disease and related conditions wherein drug metabolite levels in host blood cells determine subsequent dosage

Also Published As

Publication number Publication date
WO2005054850A3 (en) 2005-11-17
EP1695092B1 (de) 2010-06-02
EP1695092A2 (de) 2006-08-30
US20050220709A1 (en) 2005-10-06
DE602004027534D1 (de) 2010-07-15
WO2005054850A2 (en) 2005-06-16
US7524851B2 (en) 2009-04-28
CA2551010A1 (en) 2005-06-16
EP1695092B8 (de) 2010-09-22

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