ATE468403T2 - Verfahren zur extraktion und isolierung von bakteriellen hüllpolysacchariden zur verwendung als vakzine oder, an proteine gekoppelt, als konjugierte vakzine - Google Patents

Verfahren zur extraktion und isolierung von bakteriellen hüllpolysacchariden zur verwendung als vakzine oder, an proteine gekoppelt, als konjugierte vakzine Download PDF

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Publication number
ATE468403T2
ATE468403T2 AT98966468T AT98966468T ATE468403T2 AT E468403 T2 ATE468403 T2 AT E468403T2 AT 98966468 T AT98966468 T AT 98966468T AT 98966468 T AT98966468 T AT 98966468T AT E468403 T2 ATE468403 T2 AT E468403T2
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AT
Austria
Prior art keywords
vaccine
extraction
cps
proteins
isolation
Prior art date
Application number
AT98966468T
Other languages
German (de)
English (en)
Inventor
Francis Michon
Milan Blake
Original Assignee
Baxter Healthcare Sa
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22083630&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE468403(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Baxter Healthcare Sa filed Critical Baxter Healthcare Sa
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Publication of ATE468403T2 publication Critical patent/ATE468403T2/de

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
AT98966468T 1997-12-23 1998-12-23 Verfahren zur extraktion und isolierung von bakteriellen hüllpolysacchariden zur verwendung als vakzine oder, an proteine gekoppelt, als konjugierte vakzine ATE468403T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6860897P 1997-12-23 1997-12-23
PCT/US1998/027375 WO1999032653A1 (en) 1997-12-23 1998-12-23 Procedures for the extraction and isolation of bacterial capsular polysaccharides for use as vaccines or linked to proteins as conjugates vaccines

Publications (1)

Publication Number Publication Date
ATE468403T2 true ATE468403T2 (de) 2010-06-15

Family

ID=22083630

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98966468T ATE468403T2 (de) 1997-12-23 1998-12-23 Verfahren zur extraktion und isolierung von bakteriellen hüllpolysacchariden zur verwendung als vakzine oder, an proteine gekoppelt, als konjugierte vakzine

Country Status (14)

Country Link
US (1) US6248570B1 (enExample)
EP (3) EP1051506B2 (enExample)
JP (2) JP4435413B2 (enExample)
KR (2) KR100757630B1 (enExample)
AT (1) ATE468403T2 (enExample)
AU (1) AU754256C (enExample)
CA (1) CA2316975C (enExample)
CZ (1) CZ302615B6 (enExample)
DE (1) DE69841676D1 (enExample)
DK (1) DK1051506T4 (enExample)
ES (2) ES2346022T3 (enExample)
HU (1) HUP0100623A3 (enExample)
NO (1) NO331100B1 (enExample)
WO (1) WO1999032653A1 (enExample)

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US6693188B2 (en) 2001-08-08 2004-02-17 Cargill Incorporated N-acetyl-D-glucosamine and process for producing N-acetyl-D-glucosamine
US7923437B2 (en) * 2001-02-16 2011-04-12 Cargill, Incorporated Water soluble β-glucan, glucosamine, and N-acetylglucosamine compositions and methods for making the same
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CN102319427A (zh) 2003-01-30 2012-01-18 诺华疫苗和诊断有限公司 抗多种脑膜炎球菌血清组的可注射性疫苗
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JP5286089B2 (ja) * 2006-01-13 2013-09-11 バクスター・インターナショナル・インコーポレイテッド ポリサッカライドを精製する方法
US10828361B2 (en) 2006-03-22 2020-11-10 Glaxosmithkline Biologicals Sa Regimens for immunisation with meningococcal conjugates
GB0605757D0 (en) * 2006-03-22 2006-05-03 Chiron Srl Separation of conjugated and unconjugated components
US10543265B2 (en) 2006-03-22 2020-01-28 Glaxosmithkline Biologicals Sa Regimens for immunisation with meningococcal conjugates
US8808707B1 (en) 2006-05-08 2014-08-19 Wyeth Llc Pneumococcal dosing regimen
EP1872791A1 (en) 2006-06-30 2008-01-02 Institut Pasteur Use of bacterial polysaccharides for biofilm inhibition
PL2115010T3 (pl) 2007-02-28 2012-07-31 Lipoxen Tech Limited Zmniejszanie zawartości endotoksyny w kwasach polisialowych
HUE038598T2 (hu) 2007-03-05 2018-10-29 Om Pharma Bakteriális extraktum légzési rendellenességekhez, és eljárás ennek elõállítására
DK2436700T5 (en) * 2007-03-23 2018-09-03 Wyeth Llc BRIEF PURIFICATION PROCEDURE FOR THE PREPARATION OF STREPTOCOCCUS PNEUMONIAE-Capsule POLYACCHARIDES
GB0818453D0 (en) 2008-10-08 2008-11-12 Novartis Ag Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
JP5339243B2 (ja) * 2008-04-24 2013-11-13 株式会社微生物化学研究所 ストレプトコッカス・スイス感染症予防用ワクチン
WO2011005587A1 (en) * 2009-06-24 2011-01-13 University Of Dubuque Vaccine compositions and methods of use to protect against infectious disease
JP5944480B2 (ja) * 2011-03-22 2016-07-05 セルム・インスティテュート・オブ・インディア・ピーブイティー．・リミテッド 多糖を調製するための新規な方法
US9400250B2 (en) 2013-09-30 2016-07-26 Han Sheng Biotech Co., Ltd. Method for analyzing mushrooms
MY186874A (en) * 2014-02-25 2021-08-26 Msd Wellcome Trust Hilleman Laboratories Pvt Ltd A novel downstream process for purifying polysaccharides
EP2942396A1 (en) 2014-05-07 2015-11-11 Novartis AG Polysaccharides produced by CPSC mutants
EP3034516A1 (en) * 2014-12-19 2016-06-22 Novartis AG Purification of streptococcal capsular polysaccharide
KR102045663B1 (ko) 2015-05-04 2019-11-15 화이자 인코포레이티드 B군 스트렙토코쿠스 폴리사카라이드-단백질 접합체, 접합체를 생산하는 방법, 접합체를 포함하는 면역원성 조성물, 및 그의 용도
WO2018104889A1 (en) * 2016-12-06 2018-06-14 Glaxosmithkline Biologicals Sa Purification process for capsular polysaccharide
KR102565771B1 (ko) * 2017-05-05 2023-08-10 세럼 인스티튜트 오브 인디아 프라이비트 리미티드 박테리아 협막 폴리사카라이드 기반 제제로부터의 불순물의 제거 방법
JP7111799B2 (ja) * 2017-07-05 2022-08-02 インベントプライズ リミテッド ライアビリティ カンパニー 溶菌酵素、接線流濾過、及びマルチモードクロマトグラフィを用いたワクチン生産のための多糖精製
SI3678654T1 (sl) 2017-09-07 2024-10-30 Merck Sharp & Dohme Llc Pnevmokokni polisaharidi in njihova uporaba v imunogenih polisaharidnih nosilnih proteinskih konjugatih
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CN117512031B (zh) * 2023-10-16 2024-06-25 江苏金迪克生物技术股份有限公司 一种肺炎球菌荚膜多糖的纯化方法

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Also Published As

Publication number Publication date
JP4435413B2 (ja) 2010-03-17
CZ302615B6 (cs) 2011-08-03
NO20003226D0 (no) 2000-06-21
EP3118225A1 (en) 2017-01-18
EP1051506A1 (en) 2000-11-15
CZ20002373A3 (cs) 2000-12-13
KR100641490B1 (ko) 2006-10-31
JP2001526902A (ja) 2001-12-25
EP2226336A1 (en) 2010-09-08
EP1051506B1 (en) 2010-05-19
US6248570B1 (en) 2001-06-19
CA2316975C (en) 2009-03-24
JP2010011862A (ja) 2010-01-21
AU754256C (en) 2004-05-20
AU754256B2 (en) 2002-11-07
ES2346022T3 (es) 2010-10-07
DE69841676D1 (de) 2010-07-01
EP1051506B2 (en) 2019-08-21
CA2316975A1 (en) 1999-07-01
EP2226336B1 (en) 2016-10-19
NO331100B1 (no) 2011-10-03
KR100757630B1 (ko) 2007-09-10
AU2307199A (en) 1999-07-12
WO1999032653A1 (en) 1999-07-01
KR20060086978A (ko) 2006-08-01
EP1051506B8 (en) 2010-09-01
HUP0100623A2 (hu) 2001-06-28
HUP0100623A3 (en) 2003-11-28
HK1147506A1 (en) 2011-08-12
DK1051506T4 (da) 2019-10-21
ES2611464T3 (es) 2017-05-09
JP5144613B2 (ja) 2013-02-13
WO1999032653A9 (en) 1999-10-28
KR20010033494A (ko) 2001-04-25
DK1051506T3 (da) 2010-09-13

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