KR100757630B1 - 신규한 추출 및 단리 방법으로 수득되는 세균성 캡슐형 다당류 - Google Patents

신규한 추출 및 단리 방법으로 수득되는 세균성 캡슐형 다당류 Download PDF

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KR100757630B1
KR100757630B1 KR1020067013976A KR20067013976A KR100757630B1 KR 100757630 B1 KR100757630 B1 KR 100757630B1 KR 1020067013976 A KR1020067013976 A KR 1020067013976A KR 20067013976 A KR20067013976 A KR 20067013976A KR 100757630 B1 KR100757630 B1 KR 100757630B1
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cps
group
type
polysaccharides
polysaccharide
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KR20060086978A (ko
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프랜시스 미숑
밀란 블레이크
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박스터 헬쓰케어 에스.에이.
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
KR1020067013976A 1997-12-23 1998-12-23 신규한 추출 및 단리 방법으로 수득되는 세균성 캡슐형 다당류 Expired - Fee Related KR100757630B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6860897P 1997-12-23 1997-12-23
US60/068,608 1997-12-23
PCT/US1998/027375 WO1999032653A1 (en) 1997-12-23 1998-12-23 Procedures for the extraction and isolation of bacterial capsular polysaccharides for use as vaccines or linked to proteins as conjugates vaccines

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020007006995A Division KR100641490B1 (ko) 1997-12-23 1998-12-23 백신용도이거나 결합백신으로서 단백질에 결합되는 세균성 캡슐형 다당류의 추출 및 단리방법

Publications (2)

Publication Number Publication Date
KR20060086978A KR20060086978A (ko) 2006-08-01
KR100757630B1 true KR100757630B1 (ko) 2007-09-10

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KR1020007006995A Expired - Lifetime KR100641490B1 (ko) 1997-12-23 1998-12-23 백신용도이거나 결합백신으로서 단백질에 결합되는 세균성 캡슐형 다당류의 추출 및 단리방법
KR1020067013976A Expired - Fee Related KR100757630B1 (ko) 1997-12-23 1998-12-23 신규한 추출 및 단리 방법으로 수득되는 세균성 캡슐형 다당류

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1020007006995A Expired - Lifetime KR100641490B1 (ko) 1997-12-23 1998-12-23 백신용도이거나 결합백신으로서 단백질에 결합되는 세균성 캡슐형 다당류의 추출 및 단리방법

Country Status (14)

Country Link
US (1) US6248570B1 (enExample)
EP (3) EP2226336B1 (enExample)
JP (2) JP4435413B2 (enExample)
KR (2) KR100641490B1 (enExample)
AT (1) ATE468403T2 (enExample)
AU (1) AU754256C (enExample)
CA (1) CA2316975C (enExample)
CZ (1) CZ302615B6 (enExample)
DE (1) DE69841676D1 (enExample)
DK (1) DK1051506T4 (enExample)
ES (2) ES2346022T3 (enExample)
HU (1) HUP0100623A3 (enExample)
NO (1) NO331100B1 (enExample)
WO (1) WO1999032653A1 (enExample)

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US8222232B2 (en) * 2001-02-16 2012-07-17 Cargill, Incorporated Glucosamine and N-acetylglucosamine compositions and methods of making the same fungal biomass
US7816514B2 (en) 2001-02-16 2010-10-19 Cargill, Incorporated Glucosamine and method of making glucosamine from microbial biomass
US20020115639A1 (en) * 2001-02-16 2002-08-22 Weiyu Fan Glucosamine and method of making glucosamine from microbial blomass
US6693188B2 (en) 2001-08-08 2004-02-17 Cargill Incorporated N-acetyl-D-glucosamine and process for producing N-acetyl-D-glucosamine
US7923437B2 (en) * 2001-02-16 2011-04-12 Cargill, Incorporated Water soluble β-glucan, glucosamine, and N-acetylglucosamine compositions and methods for making the same
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
MXPA04009339A (es) * 2002-03-26 2005-01-25 Chiron Srl Sacaridos modificados que tienen estabilidad mejorada en agua.
AU2003257003A1 (en) * 2002-07-30 2004-02-16 Baxter Healthcare S.A. Chimeric multivalent polysaccharide conjugate vaccines
US20060003965A1 (en) * 2002-11-01 2006-01-05 Fosdick Lawrence D N-acetyl-d-glucosamine (nag) supplemented food products and beverages
US20060058263A1 (en) * 2002-11-01 2006-03-16 Rogers Brent D Heat pasturized liquids containing glucosamine
PT2172213E (pt) 2003-01-30 2013-06-03 Novartis Ag Vacinas injetáveis contra múltiplos serogrupos meningocócicos
AU2004251734B2 (en) * 2003-06-23 2010-11-04 Baxalta GmbH Vaccines against group Y neisseria meningitidis and meningococcal combinations thereof
GB0406013D0 (en) * 2004-03-17 2004-04-21 Chiron Srl Analysis of saccharide vaccines without interference
JP5026266B2 (ja) * 2004-08-12 2012-09-12 リポクセン テクノロジーズ リミテッド 分別
GB0502096D0 (en) * 2005-02-01 2005-03-09 Chiron Srl Purification of streptococcal capsular polysaccharide
GB0502095D0 (en) * 2005-02-01 2005-03-09 Chiron Srl Conjugation of streptococcal capsular saccharides
CN104815327A (zh) * 2005-04-08 2015-08-05 惠氏有限责任公司 多价肺炎球菌多糖-蛋白质缀合物组合物
AU2011253684B8 (en) * 2005-04-08 2013-07-11 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
CA2620416A1 (en) * 2005-08-24 2007-03-01 Novartis Vaccines And Diagnostics S.R.L. Zwitterionization of capsular saccharides
GB0522303D0 (en) 2005-11-01 2005-12-07 Chiron Srl Culture method
CA2636983A1 (en) * 2006-01-13 2007-07-26 Baxter International Inc. Method for purifying polysaccharides
CA2646993C (en) 2006-03-22 2016-01-26 Novartis Ag Regimens for immunisation with meningococcal conjugates
US10828361B2 (en) 2006-03-22 2020-11-10 Glaxosmithkline Biologicals Sa Regimens for immunisation with meningococcal conjugates
GB0605757D0 (en) * 2006-03-22 2006-05-03 Chiron Srl Separation of conjugated and unconjugated components
US8808707B1 (en) 2006-05-08 2014-08-19 Wyeth Llc Pneumococcal dosing regimen
EP1872791A1 (en) 2006-06-30 2008-01-02 Institut Pasteur Use of bacterial polysaccharides for biofilm inhibition
PL2115010T3 (pl) 2007-02-28 2012-07-31 Lipoxen Tech Limited Zmniejszanie zawartości endotoksyny w kwasach polisialowych
PL2114421T3 (pl) 2007-03-05 2018-07-31 Om Pharma Ekstrakt bakteryjny do stosowania względem zaburzeń oddechowych i sposób jego wytwarzania
PT2129693T (pt) * 2007-03-23 2017-02-14 Wyeth Llc Processo de purificação abreviado para a produção de polissacáridos capsulares de streptococcus pneumoniae
GB0818453D0 (en) 2008-10-08 2008-11-12 Novartis Ag Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
JP5339243B2 (ja) * 2008-04-24 2013-11-13 株式会社微生物化学研究所 ストレプトコッカス・スイス感染症予防用ワクチン
US8647640B2 (en) * 2009-06-24 2014-02-11 Richard E. COWART Vaccine compositions and methods of use to protect against infectious disease
CN103687600B (zh) * 2011-03-22 2016-05-04 印度血清研究所私人有限公司 一种制备多糖的方法
US9400250B2 (en) 2013-09-30 2016-07-26 Han Sheng Biotech Co., Ltd. Method for analyzing mushrooms
MY186874A (en) * 2014-02-25 2021-08-26 Msd Wellcome Trust Hilleman Laboratories Pvt Ltd A novel downstream process for purifying polysaccharides
EP2942396A1 (en) 2014-05-07 2015-11-11 Novartis AG Polysaccharides produced by CPSC mutants
EP3034516A1 (en) * 2014-12-19 2016-06-22 Novartis AG Purification of streptococcal capsular polysaccharide
IL255106B2 (en) 2015-05-04 2023-04-01 Pfizer Protein-polysaccharide conjugates of group b streptococcus, methods for preparing conjugates, immunogenic preparations containing conjugates and their uses
WO2018104889A1 (en) 2016-12-06 2018-06-14 Glaxosmithkline Biologicals Sa Purification process for capsular polysaccharide
AU2018262438B2 (en) * 2017-05-05 2022-07-14 Serum Institute Of India Private Limited Method for removal of impurities from bacterial capsular polysaccharide based preparations
WO2019010080A1 (en) * 2017-07-05 2019-01-10 Inventprise, Llc PURIFICATION OF POLYSACCHARIDES FOR THE PRODUCTION OF VACCINES USING LYTIC ENZYMES, TANGENTIAL FILTRATION AND MULTIMODAL CHROMATOGRAPHY
PT3678654T (pt) 2017-09-07 2024-08-05 Merck Sharp & Dohme Llc Polissacáridos pneumocócicos e sua utilização em conjugados imunogénicos de polissacárido-proteína transportadora
FR3078977B1 (fr) 2018-03-16 2023-03-17 Biomerieux Sa Procede d'extraction d'acides nucleiques
CA3199094A1 (en) * 2020-10-22 2022-04-28 Pfizer Inc. Methods for purifying bacterial polysaccharides
CN117512031B (zh) * 2023-10-16 2024-06-25 江苏金迪克生物技术股份有限公司 一种肺炎球菌荚膜多糖的纯化方法

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US4413057A (en) 1980-04-14 1983-11-01 Merck & Co., Inc. Group B streptococcal capsular polysaccharides
EP0238739A1 (en) 1986-03-27 1987-09-30 Swiss Serum and Vaccine Institute Berne Klebsiella capsular polysaccharide vaccine
US5190746A (en) 1989-05-10 1993-03-02 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Plaque inhibiting oligosaccharide

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EP0238739A1 (en) 1986-03-27 1987-09-30 Swiss Serum and Vaccine Institute Berne Klebsiella capsular polysaccharide vaccine
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Also Published As

Publication number Publication date
NO20003226D0 (no) 2000-06-21
AU754256C (en) 2004-05-20
ATE468403T2 (de) 2010-06-15
DE69841676D1 (de) 2010-07-01
KR20060086978A (ko) 2006-08-01
KR100641490B1 (ko) 2006-10-31
US6248570B1 (en) 2001-06-19
CZ20002373A3 (cs) 2000-12-13
WO1999032653A9 (en) 1999-10-28
EP1051506B2 (en) 2019-08-21
ES2611464T3 (es) 2017-05-09
JP2001526902A (ja) 2001-12-25
HK1147506A1 (en) 2011-08-12
EP1051506B1 (en) 2010-05-19
DK1051506T3 (da) 2010-09-13
NO331100B1 (no) 2011-10-03
AU754256B2 (en) 2002-11-07
EP1051506B8 (en) 2010-09-01
EP3118225A1 (en) 2017-01-18
AU2307199A (en) 1999-07-12
ES2346022T3 (es) 2010-10-07
WO1999032653A1 (en) 1999-07-01
EP2226336A1 (en) 2010-09-08
CZ302615B6 (cs) 2011-08-03
DK1051506T4 (da) 2019-10-21
HUP0100623A2 (hu) 2001-06-28
HUP0100623A3 (en) 2003-11-28
CA2316975C (en) 2009-03-24
JP5144613B2 (ja) 2013-02-13
CA2316975A1 (en) 1999-07-01
KR20010033494A (ko) 2001-04-25
EP1051506A1 (en) 2000-11-15
JP4435413B2 (ja) 2010-03-17
JP2010011862A (ja) 2010-01-21
EP2226336B1 (en) 2016-10-19

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