DE60037907D1 - Verfahren zur inaktivierung von mikroorganismen - Google Patents

Verfahren zur inaktivierung von mikroorganismen

Info

Publication number
DE60037907D1
DE60037907D1 DE60037907T DE60037907T DE60037907D1 DE 60037907 D1 DE60037907 D1 DE 60037907D1 DE 60037907 T DE60037907 T DE 60037907T DE 60037907 T DE60037907 T DE 60037907T DE 60037907 D1 DE60037907 D1 DE 60037907D1
Authority
DE
Germany
Prior art keywords
microorganism
inactivant
cross
linking agent
inactivating microorganisms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60037907T
Other languages
English (en)
Other versions
DE60037907T2 (de
Inventor
Simon Johannes Barteling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INSTITUTE FOR ANIMAL SCIENCE AND HEALTH RESEAR, NL
SIMBAR HOLDING N.V., CURACAO, AN
Agricultural Research Council
Original Assignee
INST ANIMAL SCIENCE AND HEALTH
Agricultural Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INST ANIMAL SCIENCE AND HEALTH, Agricultural Research Council filed Critical INST ANIMAL SCIENCE AND HEALTH
Publication of DE60037907D1 publication Critical patent/DE60037907D1/de
Application granted granted Critical
Publication of DE60037907T2 publication Critical patent/DE60037907T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A61K39/135—Foot- and mouth-disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
    • C12N2770/32134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
    • C12N2770/32161—Methods of inactivation or attenuation
    • C12N2770/32163—Methods of inactivation or attenuation by chemical treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Fertilizers (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE60037907T 1999-12-20 2000-12-18 Verfahren zur inaktivierung von mikroorganismen Expired - Lifetime DE60037907T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ZA997757 1999-12-20
ZA9907757 1999-12-20
PCT/ZA2000/000254 WO2001046390A2 (en) 1999-12-20 2000-12-18 Method of inactivating microorganisms

Publications (2)

Publication Number Publication Date
DE60037907D1 true DE60037907D1 (de) 2008-03-13
DE60037907T2 DE60037907T2 (de) 2009-07-09

Family

ID=25588046

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60037907T Expired - Lifetime DE60037907T2 (de) 1999-12-20 2000-12-18 Verfahren zur inaktivierung von mikroorganismen

Country Status (14)

Country Link
US (1) US6673349B2 (de)
EP (1) EP1240310B1 (de)
JP (1) JP2003517834A (de)
AT (1) ATE384786T1 (de)
AU (1) AU782907B2 (de)
BR (1) BR0016563A (de)
CA (1) CA2394946C (de)
CY (1) CY1107420T1 (de)
DE (1) DE60037907T2 (de)
DK (1) DK1240310T3 (de)
ES (1) ES2300286T3 (de)
PT (1) PT1240310E (de)
TR (1) TR200202104T2 (de)
WO (1) WO2001046390A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE526034T1 (de) * 2004-01-21 2011-10-15 Merial Ltd Verbesserte inaktivierte fcv-vakzinen
US20120164135A1 (en) * 2008-12-19 2012-06-28 Kabushiki Kaisha Saiwai Medix Method for preparing comprehensive anti-surface antibody using microorganism immobilized as antigen with protein crosslinking and immobilization reagent
WO2010144797A2 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Influenza vaccines with enhanced immunogenicity and uses thereof
CN102406931B (zh) * 2011-11-25 2014-02-05 成都康华生物制品有限公司 大流行流感病毒裂解疫苗
CN105056225B (zh) * 2015-07-30 2018-01-16 成都天邦生物制品有限公司 一种灭活疫苗的制备方法
AU2017207076B2 (en) * 2016-01-15 2021-04-29 Km Biologics Co., Ltd. Vaccine containing immobilized virus particles
CN114540317A (zh) * 2022-03-17 2022-05-27 新疆方牧生物科技有限公司 一种悬浮培养口蹄病毒灭活的工艺方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1924303A1 (de) 1969-05-13 1970-12-17 Bayer Ag AEthylaethylenimin als Inaktivierungsmittel
US5069901A (en) * 1988-02-03 1991-12-03 Jones Elaine V Preparation of a recombinant subunit vaccine against pseudorabies infection
US5242686A (en) 1990-11-07 1993-09-07 American Home Products Corporation Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same
GB9110808D0 (en) * 1991-05-17 1991-07-10 Retroscreen Ltd Aids vaccine and method for its production
CZ289743B6 (cs) * 1993-02-08 2002-03-13 Bayer Corporation Izolát viru vepřového reprodukčního a respiračního syndromu PRRSV, způsob kultivace PRRSV, tkáňová kultura, způsob přípravy vakcíny a vakcína obsahující PRRSV izolát
NZ327015A (en) * 1996-02-23 2000-04-28 Procter & Gamble Disinfecting compositions comprising peroxygen bleach, at least one amine oxide surfactant, glutaraldehyde and an antimicrobial essential oil.

Also Published As

Publication number Publication date
EP1240310A2 (de) 2002-09-18
JP2003517834A (ja) 2003-06-03
CY1107420T1 (el) 2012-12-19
CA2394946C (en) 2010-12-14
AU2979601A (en) 2001-07-03
BR0016563A (pt) 2002-09-10
DK1240310T3 (da) 2008-05-26
US20030035811A1 (en) 2003-02-20
ATE384786T1 (de) 2008-02-15
DE60037907T2 (de) 2009-07-09
AU782907B2 (en) 2005-09-08
CA2394946A1 (en) 2001-06-28
WO2001046390A3 (en) 2001-12-20
ES2300286T3 (es) 2008-06-16
TR200202104T2 (tr) 2002-12-23
US6673349B2 (en) 2004-01-06
EP1240310B1 (de) 2008-01-23
WO2001046390A2 (en) 2001-06-28
PT1240310E (pt) 2008-05-05

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AGRICULTURAL RESEARCH COUNCIL, PRETORIA, ZA

Owner name: INSTITUTE FOR ANIMAL SCIENCE AND HEALTH RESEAR, NL

Owner name: SIMBAR HOLDING N.V., CURACAO, AN