BR0016563A - Método de inativação de microorganismos - Google Patents

Método de inativação de microorganismos

Info

Publication number
BR0016563A
BR0016563A BR0016563-8A BR0016563A BR0016563A BR 0016563 A BR0016563 A BR 0016563A BR 0016563 A BR0016563 A BR 0016563A BR 0016563 A BR0016563 A BR 0016563A
Authority
BR
Brazil
Prior art keywords
microorganism
inactivant
cross
linking agent
inactivation method
Prior art date
Application number
BR0016563-8A
Other languages
English (en)
Inventor
Simon Johannes Barteling
Original Assignee
Agricultural Research Council
Inst Animal Science And Health
Simon Johannes Barteling
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agricultural Research Council, Inst Animal Science And Health, Simon Johannes Barteling filed Critical Agricultural Research Council
Publication of BR0016563A publication Critical patent/BR0016563A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A61K39/135—Foot- and mouth-disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
    • C12N2770/32134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
    • C12N2770/32161—Methods of inactivation or attenuation
    • C12N2770/32163—Methods of inactivation or attenuation by chemical treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Fertilizers (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"MéTODO DE INATIVAçãO DE MICROORGANISMOS". Esta invenção refere-se a métodos de inativação de um microorganismo e preparação de uma vacina incluindo a etapa de aplicar ao referido microorganismo um agente de reticulação simultaneamente com um inativante separado. Esta invenção refere-se ainda a vacinas preparadas por tais métodos e a um kit incluindo tal microorganismo inativado. O agente de reticulação é tipicamente formaldeído (FA) e o inativante tipicamente etilenoimina binária (BEI).
BR0016563-8A 1999-12-20 2000-12-18 Método de inativação de microorganismos BR0016563A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA997757 1999-12-20
PCT/ZA2000/000254 WO2001046390A2 (en) 1999-12-20 2000-12-18 Method of inactivating microorganisms

Publications (1)

Publication Number Publication Date
BR0016563A true BR0016563A (pt) 2002-09-10

Family

ID=25588046

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0016563-8A BR0016563A (pt) 1999-12-20 2000-12-18 Método de inativação de microorganismos

Country Status (14)

Country Link
US (1) US6673349B2 (pt)
EP (1) EP1240310B1 (pt)
JP (1) JP2003517834A (pt)
AT (1) ATE384786T1 (pt)
AU (1) AU782907B2 (pt)
BR (1) BR0016563A (pt)
CA (1) CA2394946C (pt)
CY (1) CY1107420T1 (pt)
DE (1) DE60037907T2 (pt)
DK (1) DK1240310T3 (pt)
ES (1) ES2300286T3 (pt)
PT (1) PT1240310E (pt)
TR (1) TR200202104T2 (pt)
WO (1) WO2001046390A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1734992T3 (da) * 2004-01-21 2011-12-05 Merial Ltd Forbedrede inaktiverede FCV-vacciner
AU2009327837A1 (en) * 2008-12-19 2011-07-28 Kabushiki Kaisha Saiwai Medical Method for preparing comprehensive anti-surface antibody using microorganism immobilized as antigen with protein crosslinking and immobilization reagent
WO2010144797A2 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Influenza vaccines with enhanced immunogenicity and uses thereof
CN102406931B (zh) * 2011-11-25 2014-02-05 成都康华生物制品有限公司 大流行流感病毒裂解疫苗
CN105056225B (zh) * 2015-07-30 2018-01-16 成都天邦生物制品有限公司 一种灭活疫苗的制备方法
AU2017207076B2 (en) 2016-01-15 2021-04-29 Km Biologics Co., Ltd. Vaccine containing immobilized virus particles
CN114540317A (zh) * 2022-03-17 2022-05-27 新疆方牧生物科技有限公司 一种悬浮培养口蹄病毒灭活的工艺方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1924303A1 (de) 1969-05-13 1970-12-17 Bayer Ag AEthylaethylenimin als Inaktivierungsmittel
US5069901A (en) * 1988-02-03 1991-12-03 Jones Elaine V Preparation of a recombinant subunit vaccine against pseudorabies infection
US5242686A (en) * 1990-11-07 1993-09-07 American Home Products Corporation Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same
GB9110808D0 (en) * 1991-05-17 1991-07-10 Retroscreen Ltd Aids vaccine and method for its production
ES2152304T3 (es) * 1993-02-08 2001-02-01 Bayer Ag Procedimiento para el crecimiento del virus del sindrome reproductivo y respiratorio porcino y su uso en vacunas.
KR19990077187A (ko) * 1996-02-23 1999-10-25 데이비드 엠 모이어 소독 조성물

Also Published As

Publication number Publication date
TR200202104T2 (tr) 2002-12-23
PT1240310E (pt) 2008-05-05
AU2979601A (en) 2001-07-03
US6673349B2 (en) 2004-01-06
WO2001046390A3 (en) 2001-12-20
US20030035811A1 (en) 2003-02-20
DE60037907T2 (de) 2009-07-09
ATE384786T1 (de) 2008-02-15
CY1107420T1 (el) 2012-12-19
CA2394946C (en) 2010-12-14
ES2300286T3 (es) 2008-06-16
WO2001046390A2 (en) 2001-06-28
CA2394946A1 (en) 2001-06-28
AU782907B2 (en) 2005-09-08
DE60037907D1 (de) 2008-03-13
JP2003517834A (ja) 2003-06-03
EP1240310B1 (en) 2008-01-23
EP1240310A2 (en) 2002-09-18
DK1240310T3 (da) 2008-05-26

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 13A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2257 DE 08/04/2014.