ATE384068T1 - Thiazolo(4,5-d)pyrimidinverbindungen zur behandlung von rheumathoider arthritis - Google Patents

Thiazolo(4,5-d)pyrimidinverbindungen zur behandlung von rheumathoider arthritis

Info

Publication number
ATE384068T1
ATE384068T1 AT03015019T AT03015019T ATE384068T1 AT E384068 T1 ATE384068 T1 AT E384068T1 AT 03015019 T AT03015019 T AT 03015019T AT 03015019 T AT03015019 T AT 03015019T AT E384068 T1 ATE384068 T1 AT E384068T1
Authority
AT
Austria
Prior art keywords
thiazolo
treatment
pyrimidine compounds
rheumathoid arthritis
solvate
Prior art date
Application number
AT03015019T
Other languages
English (en)
Inventor
Roger Bonnert
Simon Fraser Hunt
Paul Willis
Iain Walthers
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Application granted granted Critical
Publication of ATE384068T1 publication Critical patent/ATE384068T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT03015019T 1999-10-01 2000-09-26 Thiazolo(4,5-d)pyrimidinverbindungen zur behandlung von rheumathoider arthritis ATE384068T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9903544A SE9903544D0 (sv) 1999-10-01 1999-10-01 Novel compounds

Publications (1)

Publication Number Publication Date
ATE384068T1 true ATE384068T1 (de) 2008-02-15

Family

ID=20417218

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03015019T ATE384068T1 (de) 1999-10-01 2000-09-26 Thiazolo(4,5-d)pyrimidinverbindungen zur behandlung von rheumathoider arthritis
AT00960891T ATE257838T1 (de) 1999-10-01 2000-09-26 Neue thiazolo(4,5-d)pyrimidinverbindungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT00960891T ATE257838T1 (de) 1999-10-01 2000-09-26 Neue thiazolo(4,5-d)pyrimidinverbindungen

Country Status (27)

Country Link
US (3) US6790850B1 (de)
EP (2) EP1222195B1 (de)
JP (1) JP4824889B2 (de)
KR (1) KR100765051B1 (de)
CN (1) CN1210279C (de)
AT (2) ATE384068T1 (de)
AU (1) AU777872B2 (de)
BR (1) BR0014334A (de)
CA (1) CA2385269C (de)
CZ (1) CZ20021113A3 (de)
DE (2) DE60007768T2 (de)
DK (1) DK1222195T3 (de)
EE (1) EE05037B1 (de)
ES (2) ES2213043T3 (de)
HK (1) HK1052009A1 (de)
HU (1) HUP0204246A3 (de)
IL (2) IL148910A0 (de)
IS (1) IS2229B (de)
MX (1) MXPA02003263A (de)
NO (1) NO327706B1 (de)
NZ (1) NZ517880A (de)
PT (1) PT1222195E (de)
SE (1) SE9903544D0 (de)
TW (1) TWI260324B (de)
UA (1) UA73521C2 (de)
WO (1) WO2001025242A1 (de)
ZA (1) ZA200202380B (de)

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GB2359078A (en) 2000-02-11 2001-08-15 Astrazeneca Uk Ltd Pharmaceutically active pyrimidine derivatives
GB2359551A (en) * 2000-02-23 2001-08-29 Astrazeneca Uk Ltd Pharmaceutically active pyrimidine derivatives
SE0003828D0 (sv) 2000-10-20 2000-10-20 Astrazeneca Ab Novel compounds
SE0101322D0 (sv) * 2001-04-12 2001-04-12 Astrazeneca Ab Novel compounds
SE0102716D0 (sv) * 2001-08-14 2001-08-14 Astrazeneca Ab Novel compounds
JP4464136B2 (ja) 2001-12-06 2010-05-19 メルク・シャープ・エンド・ドーム・コーポレイション 有糸分裂キネシン阻害薬
JP4467979B2 (ja) 2001-12-06 2010-05-26 メルク・シャープ・エンド・ドーム・コーポレイション 有糸分裂キネシン阻害剤
GB0217431D0 (en) * 2002-07-27 2002-09-04 Astrazeneca Ab Novel compounds
KR20050067383A (ko) 2002-08-06 2005-07-01 아스트라제네카 아베 Ｔｉｅ2(ｔｅｋ) 활성을 갖는 축합 피리딘 및 피리미딘
DE60318219T2 (de) 2002-08-24 2009-01-15 Astrazeneca Ab PYRIMIDINDERIVATE ALS MODULATOREN DER AKTIVITuT VON CHEMOKINREZEPTOREN
GB0221829D0 (en) * 2002-09-20 2002-10-30 Astrazeneca Ab Novel compound
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GB0328243D0 (en) * 2003-12-05 2004-01-07 Astrazeneca Ab Methods
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Also Published As

Publication number Publication date
HK1052009A1 (en) 2003-08-29
BR0014334A (pt) 2002-06-11
EP1348709A2 (de) 2003-10-01
HUP0204246A3 (en) 2006-01-30
EP1348709B1 (de) 2008-01-16
EE200200174A (et) 2003-04-15
IL148910A0 (en) 2002-09-12
IS6306A (is) 2002-03-18
US6790850B1 (en) 2004-09-14
DE60007768T2 (de) 2004-12-02
ZA200202380B (en) 2003-10-29
EP1348709A3 (de) 2003-11-19
ES2298451T3 (es) 2008-05-16
US20040224961A1 (en) 2004-11-11
US20090281123A1 (en) 2009-11-12
NO20021448D0 (no) 2002-03-22
NO327706B1 (no) 2009-09-14
JP4824889B2 (ja) 2011-11-30
PL365778A1 (en) 2005-01-10
KR20020032635A (ko) 2002-05-03
NZ517880A (en) 2003-09-26
NO20021448L (no) 2002-05-22
CZ20021113A3 (cs) 2002-06-12
ES2213043T3 (es) 2004-08-16
CN1210279C (zh) 2005-07-13
US8143261B2 (en) 2012-03-27
AU7304900A (en) 2001-05-10
DE60037836D1 (de) 2008-03-06
KR100765051B1 (ko) 2007-10-09
SE9903544D0 (sv) 1999-10-01
IL148910A (en) 2006-10-31
CA2385269C (en) 2010-08-17
WO2001025242A1 (en) 2001-04-12
EE05037B1 (et) 2008-06-16
DK1222195T3 (da) 2004-04-19
IS2229B (is) 2007-04-15
EP1222195A1 (de) 2002-07-17
DE60007768D1 (de) 2004-02-19
AU777872B2 (en) 2004-11-04
CA2385269A1 (en) 2001-04-12
TWI260324B (en) 2006-08-21
EP1222195B1 (de) 2004-01-14
UA73521C2 (en) 2005-08-15
MXPA02003263A (es) 2002-09-30
PT1222195E (pt) 2004-05-31
ATE257838T1 (de) 2004-01-15
DE60037836T2 (de) 2009-01-15
HUP0204246A2 (hu) 2003-04-28
JP2003511384A (ja) 2003-03-25
CN1402730A (zh) 2003-03-12

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