ATE356838T1 - Biosynthetische matrix und deren verwendung - Google Patents
Biosynthetische matrix und deren verwendungInfo
- Publication number
- ATE356838T1 ATE356838T1 AT03783866T AT03783866T ATE356838T1 AT E356838 T1 ATE356838 T1 AT E356838T1 AT 03783866 T AT03783866 T AT 03783866T AT 03783866 T AT03783866 T AT 03783866T AT E356838 T1 ATE356838 T1 AT E356838T1
- Authority
- AT
- Austria
- Prior art keywords
- matrix
- bio
- vivo
- synthetic
- polymer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/52—Amides or imides
- C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/10—Hair or skin implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/142—Cornea, e.g. artificial corneae, keratoprostheses or corneal implants for repair of defective corneal tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/26—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F246/00—Copolymers in which the nature of only the monomers in minority is defined
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Vascular Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Botany (AREA)
- Developmental Biology & Embryology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Prostheses (AREA)
- Eyeglasses (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2397379 | 2002-08-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE356838T1 true ATE356838T1 (de) | 2007-04-15 |
Family
ID=31501599
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03783866T ATE356838T1 (de) | 2002-08-09 | 2003-08-11 | Biosynthetische matrix und deren verwendung |
Country Status (13)
Country | Link |
---|---|
US (3) | US20060134050A1 (de) |
EP (2) | EP1741457A1 (de) |
JP (2) | JP2006516038A (de) |
KR (1) | KR101053792B1 (de) |
CN (1) | CN100491424C (de) |
AT (1) | ATE356838T1 (de) |
AU (1) | AU2003254674A1 (de) |
BR (1) | BR0313726A (de) |
DE (1) | DE60312525T2 (de) |
ES (1) | ES2283849T3 (de) |
HK (1) | HK1078886A1 (de) |
MX (1) | MXPA05001570A (de) |
WO (1) | WO2004014969A1 (de) |
Families Citing this family (100)
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WO2004024035A1 (en) | 2002-09-13 | 2004-03-25 | Ocular Sciences, Inc. | Devices and methods for improving vision |
US20040120982A1 (en) * | 2002-12-19 | 2004-06-24 | Zanini Diana | Biomedical devices with coatings attached via latent reactive components |
TWI354021B (en) * | 2002-12-23 | 2011-12-11 | Alcon Inc | Compositions and methods for inhibiting protein on |
US7628810B2 (en) | 2003-05-28 | 2009-12-08 | Acufocus, Inc. | Mask configured to maintain nutrient transport without producing visible diffraction patterns |
US20050046794A1 (en) | 2003-06-17 | 2005-03-03 | Silvestrini Thomas A. | Method and apparatus for aligning a mask with the visual axis of an eye |
CN1956994B (zh) * | 2004-03-31 | 2012-09-05 | 特许技术开发株式会社 | 上皮系细胞增殖促进剂 |
EP1776148B1 (de) * | 2004-08-13 | 2019-03-06 | Ottawa Hospital Research Institute | Ophthalmische vorrichtungen und verwandte verfahren und zusammensetzungen |
US8246569B1 (en) | 2004-08-17 | 2012-08-21 | California Institute Of Technology | Implantable intraocular pressure drain |
KR101159071B1 (ko) * | 2005-01-14 | 2012-06-26 | 삼성전자주식회사 | 신규한 히드로겔 공중합체, 상기 공중합체가 코팅되어있는 기판, 상기 공중합체를 이용하여 마이크로어레이를제조하는 방법 및 그에 의하여 제조된 마이크로어레이 |
US9999497B2 (en) * | 2005-01-31 | 2018-06-19 | Yichieh Shiuey | Corneal implants and methods and systems for placement |
US7976577B2 (en) * | 2005-04-14 | 2011-07-12 | Acufocus, Inc. | Corneal optic formed of degradation resistant polymer |
US20070148246A1 (en) * | 2005-08-11 | 2007-06-28 | Dan Luo | Nucleic Acid-Based Matrixes |
WO2007028258A2 (en) * | 2005-09-09 | 2007-03-15 | Ottawa Health Research Institute | Interpenetrating networks, and related methods and compositions |
JP2007126490A (ja) * | 2005-11-01 | 2007-05-24 | Univ Of Tokushima | アミド基含有高分子化合物およびその製造方法 |
CA2833354C (en) | 2006-03-14 | 2015-12-15 | University Of Southern California | Mems device and method for delivery of therapeutic agents |
US7883520B2 (en) | 2006-04-10 | 2011-02-08 | Forsight Labs, Llc | Corneal epithelial pocket formation systems, components and methods |
WO2008045904A2 (en) * | 2006-10-10 | 2008-04-17 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Thermoresponsive, biodegradable, elastomeric material |
AU2007334394B2 (en) | 2006-12-15 | 2013-06-06 | Lifebond Ltd. | Gelatin-transglutaminase hemostatic dressings and sealants |
US20080274054A1 (en) * | 2007-05-01 | 2008-11-06 | Taipei Veterans General Hospital | Composite for Thermo-Sensitive Cell-Tissue Transplanted Scaffold and Use thereof |
US20100178316A1 (en) * | 2007-05-30 | 2010-07-15 | Anuj Chauhan | Extended release of bioactive molecules from silicone hydrogels |
US8252607B2 (en) * | 2007-06-06 | 2012-08-28 | Gautam Gupta | Bio-compatible hybrid organic/inorganic gels: vapor phase synthesis |
WO2009005769A2 (en) * | 2007-06-29 | 2009-01-08 | The Trustees Of The University Of Pennsylvania | Soft gel systems in modulating stem cell development |
US8075909B2 (en) * | 2007-09-04 | 2011-12-13 | University Of Florida Research Foundation, Incorporated | Contact lens based bioactive agent delivery system |
JP5387850B2 (ja) * | 2007-09-12 | 2014-01-15 | Jsr株式会社 | タンパク安定化剤およびその製造方法、タンパク安定化剤の使用方法、ならびにタンパク安定化方法 |
WO2009042768A1 (en) * | 2007-09-25 | 2009-04-02 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Triggerably dissolvable hollow fibers for controlled delivery |
CN101396569B (zh) * | 2007-09-27 | 2013-04-10 | 北京师范大学 | 以生物体组织为支架的复合水凝胶、其制备方法及其用途 |
US8293510B2 (en) * | 2007-11-16 | 2012-10-23 | University Of Kansas | Method of preparing a hydrogel network encapsulating cells |
US9308124B2 (en) | 2007-12-20 | 2016-04-12 | University Of Southern California | Apparatus and methods for delivering therapeutic agents |
MX2010007382A (es) | 2008-01-03 | 2010-12-20 | Univ Southern California | Dispositivos implantables para suministro de farmacos, y aparato y metodos para recargar los dispositivos. |
SG188096A1 (en) * | 2008-01-30 | 2013-03-28 | Geron Corp | Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells |
DK2247716T3 (da) * | 2008-01-30 | 2012-05-29 | Geron Corp | Syntetiske overflader til dyrkning af celler i kemisk defineret medie |
WO2009099539A2 (en) * | 2008-01-30 | 2009-08-13 | Corning Incorporated | (meth)acrylate surfaces for cell culture, methods of making and using the surfaces |
CA2712891A1 (en) | 2008-01-30 | 2009-08-06 | Corning Incorporated | Synthetic surfaces for culturing stem cell derived cardiomyocytes |
US8329469B2 (en) * | 2008-01-30 | 2012-12-11 | Geron Corporation | Swellable (meth)acrylate surfaces for culturing cells in chemically defined media |
JP5739668B2 (ja) * | 2008-02-13 | 2015-06-24 | ハイパーブランチ メディカル テクノロジー, インコーポレイテッド | 調節可能な分解速度を有する架橋ポリアルキレンイミンヒドロゲル |
FR2927902B1 (fr) * | 2008-02-26 | 2011-11-11 | Oreal | Polymere ethylenique statistique comprenant un groupe reactif et un groupe ionisable, composition cosmetique et procede de traitement cosmetique. |
KR101683042B1 (ko) | 2008-04-04 | 2016-12-06 | 포사이트 비젼4, 인크. | 통증 관리 및 시력을 위한 치료 장치 |
US8083347B2 (en) * | 2008-04-29 | 2011-12-27 | Ocugenics, LLC | Drug delivery system and methods of use |
US8361492B2 (en) * | 2008-04-29 | 2013-01-29 | Ocugenics, LLC | Drug delivery system and methods of use |
US9849238B2 (en) | 2008-05-08 | 2017-12-26 | Minipumps, Llc | Drug-delivery pump with intelligent control |
MX2010012213A (es) | 2008-05-08 | 2011-05-03 | Minipumps Llc | Bombas implantables y cánulas para las mismas. |
US8231609B2 (en) | 2008-05-08 | 2012-07-31 | Minipumps, Llc | Drug-delivery pumps and methods of manufacture |
JP2011519695A (ja) | 2008-05-08 | 2011-07-14 | リプレニッシュ パンプス, エルエルシー | 植設可能な薬物送達デバイスおよびそのデバイスを充填する装置および方法 |
WO2009137829A2 (en) | 2008-05-09 | 2009-11-12 | Wake Forest University Health Sciences | Directed stem cell recruitment |
CN102124058B (zh) | 2008-06-18 | 2014-05-28 | 生命连结有限公司 | 改进的交联组合物 |
US20100080840A1 (en) * | 2008-07-31 | 2010-04-01 | Michael Cho | Hybrid superporous hydrogel scaffold for cornea regeneration |
US20110269208A1 (en) * | 2008-08-15 | 2011-11-03 | The Trustees Of The University Of Pennsylvania | Cross-linked polymer network formed by sequential cross-linking |
FR2938544B1 (fr) * | 2008-11-20 | 2011-01-21 | Univ Cergy Pontoise | Materiaux sous forme de reseaux interpenetres de polymeres associant un gel de fibrine et un reseau de polyethylene glycol |
US8109997B2 (en) * | 2009-01-18 | 2012-02-07 | Eyeon Medical Ltd. | Hydrophobic pseudo-endothelial implants for treating corneal edema |
CN101543642B (zh) * | 2009-04-02 | 2012-06-27 | 天津大学 | 胶原基互穿聚合物网络组织工程角膜替代物及其制备方法 |
WO2010127254A2 (en) * | 2009-04-30 | 2010-11-04 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Thermoresponsive, biodegradable, elastomeric material and uses therefor |
US8362144B2 (en) * | 2009-05-21 | 2013-01-29 | Corning Incorporated | Monomers for making polymeric cell culture surface |
WO2011005974A2 (en) * | 2009-07-08 | 2011-01-13 | Northwestern University | Interpenetrating biomaterial matrices and uses thereof |
US10004593B2 (en) | 2009-08-13 | 2018-06-26 | Acufocus, Inc. | Intraocular lens with elastic mask |
WO2011020078A1 (en) | 2009-08-13 | 2011-02-17 | Acufocus, Inc. | Masked intraocular implants and lenses |
EP2464310B1 (de) | 2009-08-13 | 2019-02-27 | CorneaGen Inc. | Hornhauteinlage mit nährstofftransportstrukturen |
JP5758388B2 (ja) | 2009-08-18 | 2015-08-05 | ミニパンプス, エルエルシー | 適応制御を有する電解質薬物送達ポンプ |
NO2490635T3 (de) | 2009-10-23 | 2018-02-03 | ||
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EP2603580B1 (de) | 2010-08-13 | 2017-04-12 | Wake Forest University Health Sciences | Verfahren zur in-vitro-herstellung eines gewebegezüchteten muskelreparatur-konstrukts zur in-vivo-implantation |
US9421307B2 (en) | 2010-08-17 | 2016-08-23 | University of Pittsburgh—of the Commonwealth System of Higher Education | Biohybrid composite scaffold |
ES2940188T3 (es) | 2010-09-30 | 2023-05-04 | Keramed Inc | Córnea artificial deformable de forma reversible |
US9175153B2 (en) | 2011-03-08 | 2015-11-03 | The Johns Hopkins University | Cellulose hydrogel compositions and contact lenses for corneal applications |
US9211256B2 (en) | 2011-03-08 | 2015-12-15 | The Johns Hopkins University | Wound healing compositions comprising biocompatible cellulose hydrogel membranes and methods of use thereof |
US8871016B2 (en) | 2011-08-03 | 2014-10-28 | The Johns Hopkins University | Cellulose-based hydrogels and methods of making thereof |
US9603997B2 (en) | 2011-03-14 | 2017-03-28 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
US9919099B2 (en) | 2011-03-14 | 2018-03-20 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
US10286146B2 (en) | 2011-03-14 | 2019-05-14 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
WO2013082545A1 (en) | 2011-12-02 | 2013-06-06 | Acufocus, Inc. | Ocular mask having selective spectral transmission |
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CN100491424C (zh) | 2009-05-27 |
US20060134050A1 (en) | 2006-06-22 |
CN1688622A (zh) | 2005-10-26 |
JP2006516038A (ja) | 2006-06-15 |
EP1530600B1 (de) | 2007-03-14 |
MXPA05001570A (es) | 2005-08-19 |
ES2283849T3 (es) | 2007-11-01 |
EP1530600A1 (de) | 2005-05-18 |
HK1078886A1 (en) | 2006-03-24 |
DE60312525T2 (de) | 2007-12-06 |
EP1741457A1 (de) | 2007-01-10 |
KR20050083626A (ko) | 2005-08-26 |
US20060246113A1 (en) | 2006-11-02 |
KR101053792B1 (ko) | 2011-08-04 |
BR0313726A (pt) | 2005-06-14 |
AU2003254674A1 (en) | 2004-02-25 |
WO2004014969A1 (en) | 2004-02-19 |
JP2008093451A (ja) | 2008-04-24 |
US20150071871A1 (en) | 2015-03-12 |
DE60312525D1 (de) | 2007-04-26 |
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