ATE334392T1 - Vorrichtungen und verfahren zur abtrennung zellulärer blutkomponenten von flüssigen blutanteilen - Google Patents

Vorrichtungen und verfahren zur abtrennung zellulärer blutkomponenten von flüssigen blutanteilen

Info

Publication number
ATE334392T1
ATE334392T1 AT96915543T AT96915543T ATE334392T1 AT E334392 T1 ATE334392 T1 AT E334392T1 AT 96915543 T AT96915543 T AT 96915543T AT 96915543 T AT96915543 T AT 96915543T AT E334392 T1 ATE334392 T1 AT E334392T1
Authority
AT
Austria
Prior art keywords
blood
pad
blood components
cellular components
liquid portion
Prior art date
Application number
AT96915543T
Other languages
English (en)
Inventor
Wayne H Schrier
Corey L Jaseph
Ronald J Schoengold
Franco Ruggeri
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Application granted granted Critical
Publication of ATE334392T1 publication Critical patent/ATE334392T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5002—Partitioning blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/521—Single-layer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525—Multi-layer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/205—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Campylobacter (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/805—Test papers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/97—Test strip or test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81—Tube, bottle, or dipstick
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • External Artificial Organs (AREA)
AT96915543T 1995-05-09 1996-05-07 Vorrichtungen und verfahren zur abtrennung zellulärer blutkomponenten von flüssigen blutanteilen ATE334392T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43785095A 1995-05-09 1995-05-09

Publications (1)

Publication Number Publication Date
ATE334392T1 true ATE334392T1 (de) 2006-08-15

Family

ID=23738175

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96915543T ATE334392T1 (de) 1995-05-09 1996-05-07 Vorrichtungen und verfahren zur abtrennung zellulärer blutkomponenten von flüssigen blutanteilen

Country Status (10)

Country Link
US (3) US6069014A (de)
EP (1) EP0832430B1 (de)
JP (3) JPH11505327A (de)
CN (1) CN1155827C (de)
AT (1) ATE334392T1 (de)
CA (1) CA2217210A1 (de)
DE (1) DE69636389T2 (de)
DK (1) DK0832430T3 (de)
ES (1) ES2268706T3 (de)
WO (1) WO1996035952A1 (de)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100241928B1 (ko) * 1997-03-31 2000-03-02 박종근 다공성 박막 위에 전극이 일체로 형성된 정량장치 및 이를 이용한 정량방법
ATE297016T1 (de) * 1997-10-07 2005-06-15 Ucb Sa Testvorrichtung und verfahren zur bestimmung von analyten in einem flüssigen milchprodukt
GB9821526D0 (en) * 1998-10-02 1998-11-25 Genosis Inc Capture assay
US6036659A (en) 1998-10-09 2000-03-14 Flexsite Diagnostics, Inc. Collection device for biological samples and methods of use
US6551842B1 (en) 1999-03-26 2003-04-22 Idexx Laboratories, Inc. Method and device for detecting analytes in fluids
US6511814B1 (en) * 1999-03-26 2003-01-28 Idexx Laboratories, Inc. Method and device for detecting analytes in fluids
GB9929272D0 (en) * 1999-12-10 2000-02-02 Diagnology Limited Assay
US6316205B1 (en) * 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
EP1271147A4 (de) * 2000-03-17 2004-09-22 Sanwa Kagaku Kenkyusho Co Testpapier
EP1202061B1 (de) 2000-06-01 2008-05-14 Matsushita Electric Industrial Co., Ltd. Biosensor und verfahren zum analysieren von blutkomponenten
DE60142394D1 (de) 2000-06-28 2010-07-29 Panasonic Corp Biozensor
US6612447B1 (en) * 2000-07-24 2003-09-02 Baxter International Inc. Blood collection systems and filters using a porous membrane element
US20020036170A1 (en) * 2000-08-11 2002-03-28 Harvey Michael A. Lateral flower plasma separation device
CN1302285C (zh) * 2001-01-12 2007-02-28 东丽株式会社 纤维、纤维排列体、选择性结合反应结果测定方法和选择性结合方法
US7867756B2 (en) 2001-04-12 2011-01-11 Arkray, Inc. Specimen analyzing implement
US8101077B2 (en) * 2001-05-07 2012-01-24 Sivaprasad Sukavaneshvar Device for separating platelets from fluid suspensions
US7011852B2 (en) * 2001-05-07 2006-03-14 Hemogenesis, Llc Separation of platelets from whole blood for use as a healant
KR20010085007A (ko) * 2001-07-12 2001-09-07 김희태 반정량 멤브레인 면역 크로마토그래프 기법 및 이의제조방법.
US7569184B2 (en) * 2002-04-23 2009-08-04 Home Access Health Corporation Quantitative analysis of a biological sample of unknown quantity
US7611670B2 (en) * 2002-04-23 2009-11-03 Home Access Health Corporation Quantitative analysis of a biological sample of unknown quantity
ATE520034T1 (de) 2002-04-23 2011-08-15 Home Access Health Corp Quantitative analyse einer biologischen probe unbekannter menge
US20040048359A1 (en) * 2002-07-12 2004-03-11 Schmeling William R. Test strips moveable by magnetic fields
JP4339570B2 (ja) * 2002-10-25 2009-10-07 株式会社エスアールエル 血液検体キャリアー構成体
JP4742183B2 (ja) * 2003-03-10 2011-08-10 アークレイ株式会社 血球分離膜およびこれを用いた血液保持用具
US8454566B2 (en) * 2003-07-10 2013-06-04 Medtronic Minimed, Inc. Methods and compositions for the inhibition of biofilms on medical devices
US20050025823A1 (en) * 2003-07-29 2005-02-03 Fong Andy A.T. Methods of use of herbal compositions
US20060062688A1 (en) * 2004-02-03 2006-03-23 Polymer Technology Systems, Inc. Bodily fluid analysis system
US7625721B2 (en) * 2004-02-03 2009-12-01 Polymer Technology Systems, Inc. Non-precipitating bodily fluid analysis system
US8465696B2 (en) * 2004-02-03 2013-06-18 Polymer Technology Systems, Inc. Dry test strip with controlled flow and method of manufacturing same
CN100359314C (zh) * 2004-02-17 2008-01-02 陈格 液体样品的干燥保存方法
DE602005024965D1 (de) * 2004-06-07 2011-01-05 Denka Seiken Kk Chromatographische nachweisvorrichtung
JP4956705B2 (ja) * 2004-07-02 2012-06-20 株式会社三和化学研究所 免疫測定装置及び方法
US20060019406A1 (en) * 2004-07-23 2006-01-26 Ning Wei Lateral flow device for the detection of large pathogens
US7896167B2 (en) * 2004-08-05 2011-03-01 Akers Biosciences, Inc. Blood separator and method of separating a fluid fraction from whole blood
US20060062690A1 (en) * 2004-08-17 2006-03-23 Polymer Technology Systems, Inc. Apparatus and method of manufacturing bodily fluid test strip
US20060068500A1 (en) * 2004-09-28 2006-03-30 Kimberly-Clark Worldwide, Inc. Detecting yeast infections using a lateral flow assay
US7442557B1 (en) 2004-10-22 2008-10-28 Idexx Laboratories, Inc. Bi-directional flow assay device with reagent bridge
JP2006133143A (ja) * 2004-11-08 2006-05-25 Japan Vilene Co Ltd 血漿又は血清の保持材及び血液分離用具
NL1027737C2 (nl) * 2004-12-14 2006-06-16 Teststrip B V Chromatografische analyse-inrichting en test kit.
DE602006018595D1 (de) * 2005-04-08 2011-01-13 Medical Discovery Partners Llc Verfahren zum anreichern von subpopulationen seltener zellen aus dem blut
RU2413947C2 (ru) * 2005-05-23 2011-03-10 Фадиа Аб Способы и устройства для двухэтапного латерального проточного анализа
CA2612450C (en) * 2005-06-28 2014-04-29 Zbx Corporation Membrane array and analytical device
US7618810B2 (en) * 2005-12-14 2009-11-17 Kimberly-Clark Worldwide, Inc. Metering strip and method for lateral flow assay devices
US8377379B2 (en) * 2006-12-15 2013-02-19 Kimberly-Clark Worldwide, Inc. Lateral flow assay device
JP2008249606A (ja) * 2007-03-30 2008-10-16 Sysmex Corp クロマトグラフィー用試験具
JP4990692B2 (ja) * 2007-06-22 2012-08-01 株式会社ビーエル イムノクロマトグラフィー測定法及びキット
US8535617B2 (en) * 2007-11-30 2013-09-17 Kimberly-Clark Worldwide, Inc. Blood cell barrier for a lateral flow device
EP2227269B1 (de) * 2007-12-12 2021-04-28 Micropoint Bioscience Inc. Schnelle und effiziente filterung von vollblut in einer kapillar-durchflussvorrichtung
US9968931B2 (en) * 2007-12-12 2018-05-15 Nan Zhang Rapid and efficient filtering whole blood in capillary flow device
US8393198B2 (en) * 2008-01-09 2013-03-12 OronoSpectral Solutions, Inc. Apparatus and method for determining analyte content in a fluid
US8613214B2 (en) * 2008-01-09 2013-12-24 Orono Spectral Solutions, Inc. Apparatus and method for determining analyte content in a fluid
JP4428670B2 (ja) 2008-03-06 2010-03-10 Ｔａｎａｋａホールディングス株式会社 免疫学的測定法、キット及び展開溶媒
WO2009109997A1 (en) 2008-03-07 2009-09-11 Advanced Microdevices Pvt Ltd Method and device for particle removal and droplet preparation for qualitative and quantitative bioanalysis
JP2009236685A (ja) * 2008-03-27 2009-10-15 Sysmex Corp クロマトグラフィー用試験具
WO2009121043A2 (en) * 2008-03-27 2009-10-01 President And Fellows Of Harvard College Cotton thread as a low-cost multi-assay diagnostic platform
JP5117928B2 (ja) 2008-05-27 2013-01-16 富士フイルム株式会社 イムノクロマトグラフデバイス
US9952211B2 (en) 2008-06-29 2018-04-24 Realbio Technologies Ltd. Liquid-transfer device particularly useful as a capturing device in a biological assay process
KR101032691B1 (ko) * 2009-04-17 2011-05-06 (주)디지탈옵틱 신속한 혈구분리가 가능한 질병진단용 바이오센서
WO2010129302A1 (en) * 2009-04-28 2010-11-11 Innovative Laboratory Technologies, Inc. Lateral-flow immuno-chromatographic assay devices
BR112012016882B1 (pt) * 2010-01-08 2021-02-23 University Of Tasmania método de armazenamento de um fluido corpóreo para análise futura
US9816979B2 (en) * 2010-07-27 2017-11-14 Northwestern University Devices and methods for filtering blood plasma
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
CN102375055A (zh) * 2010-08-19 2012-03-14 中国人民解放军军事医学科学院微生物流行病研究所 一种多重检测免疫层析芯片
WO2013082273A1 (en) 2011-11-30 2013-06-06 Wellstat Diagnostics, Llc. Filtration module
WO2013095729A1 (en) 2011-12-22 2013-06-27 Life Technologies Corporation Sequential lateral flow capillary device for analyte determination
EP3231861B1 (de) 2012-02-03 2020-01-08 Axxin Pty Ltd Vorrichtung und verfahren zur nukleinsäureamplifikation und -detektion
WO2013147308A1 (ja) 2012-03-30 2013-10-03 積水メディカル株式会社 赤血球含有サンプル中の対象物を検出するためのイムノクロマトグラフィー用テストストリップおよびイムノクロマトグラフィーを利用した検出方法
US9625465B2 (en) 2012-05-15 2017-04-18 Defined Diagnostics, Llc Clinical diagnostic systems
US9081001B2 (en) 2012-05-15 2015-07-14 Wellstat Diagnostics, Llc Diagnostic systems and instruments
US9213043B2 (en) 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
IN2014DN10498A (de) 2012-06-13 2015-08-21 Asahi Chemical Ind
WO2014024157A1 (en) * 2012-08-08 2014-02-13 Koninklijke Philips N.V. Plasma separation using a drop of blood
US9285336B2 (en) * 2012-08-09 2016-03-15 The Board Of Trustees Of The Leland Stanford Junior University Sensing platform for quantum transduction of chemical information
US10248765B1 (en) 2012-12-05 2019-04-02 Theranos Ip Company, Llc Systems, devices, and methods for bodily fluid sample collection, transport, and handling
MX365324B (es) * 2013-03-15 2019-05-29 Theranos Ip Co Llc Metodos y dispositivos para recoleccion de muestras y separacion de muestras.
US10101293B2 (en) 2013-08-09 2018-10-16 The Board Of Trustees Of The Leland Stanford Junio Sensing platform for transduction of information
US10434508B2 (en) 2014-07-03 2019-10-08 Abionic Sa Capsule for rapid molecular quantification of a fluid sample such as whole blood
WO2016073415A2 (en) 2014-11-04 2016-05-12 Wainamics, Inc. Microscale plasma separator
US10463290B2 (en) 2014-11-14 2019-11-05 Axxin Pty Ltd. Biological sample collection and storage assembly
WO2016180990A1 (en) * 2015-05-14 2016-11-17 General Electric Company Device for separation and collection of plasma
WO2017011862A1 (en) 2015-07-17 2017-01-26 Axxin Pty Ltd Diagnostic test assembly, apparatus, method
US10371606B2 (en) 2015-07-21 2019-08-06 Theraos IP Company, LLC Bodily fluid sample collection and transport
US11247208B2 (en) 2015-09-09 2022-02-15 Labrador Diagnostics Llc Methods and devices for sample collection and sample separation
CN105445454B (zh) * 2015-11-20 2016-11-30 广州瑞博奥生物科技有限公司 一种可定量的免疫层析装置
US10983119B2 (en) * 2016-01-25 2021-04-20 General Electric Company Device for rapid diagnostic tests to detect antigens with improved sensitivity
WO2017189854A1 (en) 2016-04-28 2017-11-02 The Board Of Trustees Of The Leland Stanford Junior University Mesoscale system feedback-induced dissipation and noise suppression
JP6366025B2 (ja) * 2016-10-03 2018-08-01 セルスペクト株式会社 血漿分離装置及び血漿分離方法
WO2020049569A2 (en) 2018-09-05 2020-03-12 Hero Scientific Ltd. Testing for particulates
GB201703383D0 (en) 2017-03-02 2017-04-19 Gargle Tech Ltd Testing for particulates
US11857966B1 (en) 2017-03-15 2024-01-02 Labrador Diagnostics Llc Methods and devices for sample collection and sample separation
WO2018175169A1 (en) 2017-03-20 2018-09-27 Wainamics, Inc. Small volume self-metered blood separation device
JP7276716B2 (ja) 2017-09-27 2023-05-18 アックスイン ピーティーワイ リミテッド 診断テストシステムおよび方法
CN109541215A (zh) * 2018-12-20 2019-03-29 中国人民解放军陆军军医大学 一种肿瘤检测物及其制备方法与应用
US11885568B2 (en) 2019-01-09 2024-01-30 Lawrence Livermore National Security, Llc Systems and methods for periodic nodal surface based reactors, distributors, contactors and heat exchangers
US11389765B2 (en) * 2019-01-09 2022-07-19 Lawrence Livermore National Security, Llc Hierarchical triply periodic minimal surface structures as heat exchangers and reactors
US11850583B2 (en) 2019-06-12 2023-12-26 Siemens Healthcare Diagnostics Inc. Plasma separation and sample metering device and kits and methods of use related thereto
CN111721880B (zh) * 2020-07-02 2023-01-10 江中药业股份有限公司 一种双柱串联hplc-ms肿节风指纹图谱建立方法
CA3202405A1 (en) 2021-01-06 2022-07-14 Zvi Feldman Filtration sampling devices
CA3230920A1 (en) * 2021-09-10 2023-03-16 Jason J. SUN Agglutinating agents, devices and methods for whole blood assays

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3768978A (en) * 1971-03-01 1973-10-30 Hamilton Co Disposable pipette
US3723064A (en) * 1971-07-26 1973-03-27 L Liotta Method and device for determining the concentration of a material in a liquid
BE792129A (fr) 1971-12-06 1973-05-30 Takeda Chemical Industries Ltd Derives de pyrimido(4,5-d)pyridazine et leur procede de production
US3902964A (en) * 1971-12-13 1975-09-02 U S Medical Research And Dev I Method of and apparatus for chemically separating plasma or serum from formed elements of blood
CA1054034A (en) * 1975-06-20 1979-05-08 Barbara J. Bruschi Multilayer analytical element
US3990850A (en) * 1976-01-06 1976-11-09 Akzona Incorporated Diagnostic test card
US4110079A (en) 1977-06-09 1978-08-29 Eastman Kodak Company Analytical element for clinical analysis
US4160008A (en) * 1978-01-26 1979-07-03 Miles Laboratories, Inc. Multilayered test device for determining the presence of a liquid sample component, and method of use
JPS587332Y2 (ja) * 1978-06-06 1983-02-08 富士写真フイルム株式会社 多層血液化学分析材料
DE2932973A1 (de) * 1978-08-14 1980-02-28 Fuji Photo Film Co Ltd Integrales mehrschichtiges material fuer die chemische analyse des blutes
JPH0142041Y2 (de) * 1978-12-11 1989-12-11
US4288228A (en) * 1979-01-31 1981-09-08 Technicon Instruments Corporation Whole blood analyses and diffusion apparatus therefor
US4271119A (en) 1979-07-23 1981-06-02 Eastman Kodak Company Capillary transport device having connected transport zones
DE3029579C2 (de) 1980-08-05 1985-12-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut
US4816224A (en) * 1980-08-05 1989-03-28 Boehringer Mannheim Gmbh Device for separating plasma or serum from whole blood and analyzing the same
US4426451A (en) * 1981-01-28 1984-01-17 Eastman Kodak Company Multi-zoned reaction vessel having pressure-actuatable control means between zones
DE3323973A1 (de) * 1983-07-02 1985-01-03 Boehringer Mannheim Gmbh, 6800 Mannheim Erythrozyten-rueckhaltesubstrate
US4594327A (en) * 1983-11-02 1986-06-10 Syntex (U.S.A.) Inc. Assay method for whole blood samples
US4678757A (en) * 1985-04-11 1987-07-07 Smithkline Diagnostics, Inc. Device and method for whole blood separation and analysis
DE3523439A1 (de) * 1985-06-29 1987-01-08 Boehringer Mannheim Gmbh Testtraeger
US4790979A (en) * 1986-08-29 1988-12-13 Technimed Corporation Test strip and fixture
DE3630999A1 (de) 1986-09-12 1988-03-17 Boehringer Mannheim Gmbh Mehrschichtiger testtraeger
US4753776A (en) * 1986-10-29 1988-06-28 Biotrack, Inc. Blood separation device comprising a filter and a capillary flow pathway exiting the filter
US5135719A (en) * 1986-10-29 1992-08-04 Biotrack, Inc. Blood separation device comprising a filter and a capillary flow pathway exiting the filter
DE3643516A1 (de) 1986-12-19 1988-06-30 Boehringer Mannheim Gmbh Testtraeger fuer die analytische bestimmung von bestandteilen von koerperfluessigkeiten
DE3715485A1 (de) 1987-05-09 1988-11-17 Boehringer Mannheim Gmbh Stabilisierung von ss-galactosidase
US4943522A (en) * 1987-06-01 1990-07-24 Quidel Lateral flow, non-bibulous membrane assay protocols
US5215886A (en) 1987-06-22 1993-06-01 Patel P Jivan HDL determination in whole blood
US4987085A (en) * 1987-06-22 1991-01-22 Chemtrak Inc. Blood filtering metering device
JPH0623759B2 (ja) * 1987-07-08 1994-03-30 富士写真フイルム株式会社 全血分析要素
US4883764A (en) * 1987-07-20 1989-11-28 Kloepfer Mary A Blood test strip
US5209904A (en) * 1987-12-23 1993-05-11 Abbott Laboratories Agglutination reaction device utilizing selectively impregnated porous material
NL8800796A (nl) * 1988-03-29 1989-10-16 X Flow Bv Werkwijze voor de chemische analyse van bestanddelen van een lichaamsvloeistof, alsmede een testinrichting en testpakket voor een dergelijke analyse.
DE3814370A1 (de) * 1988-04-28 1989-11-09 Boehringer Mannheim Gmbh Testtraeger fuer die analyse einer probenfluessigkeit, verfahren zur durchfuehrung einer solchen analyse und herstellungsverfahren
US4963325A (en) 1988-05-06 1990-10-16 Hygeia Sciences, Inc. Swab expressor immunoassay device
US5096809A (en) * 1988-07-25 1992-03-17 Pacific Biotech, Inc. Whole blood assays using porous membrane support devices
US5418129A (en) * 1989-01-30 1995-05-23 The Biomembrane Institute Blood treatment method
US4933092A (en) * 1989-04-07 1990-06-12 Abbott Laboratories Methods and devices for the separation of plasma or serum from whole blood
US5064541A (en) * 1989-04-07 1991-11-12 Abbott Laboratories Devices and methods for the collection of a predetermined volume of plasma or serum
NL8901090A (nl) 1989-04-28 1990-11-16 X Flow Bv Werkwijze voor het vervaardigen van een microporeus membraan en een dergelijk membraan.
DE3922495A1 (de) * 1989-07-08 1991-01-17 Miles Inc Analyseverfahren fuer substanzen aus biologischen fluessigkeiten, insbesondere vollblut
US5306623A (en) * 1989-08-28 1994-04-26 Lifescan, Inc. Visual blood glucose concentration test strip
DE69021327T2 (de) * 1989-11-08 1996-03-14 Chemtrak Inc Verbesserung in einem gerätefreien auf Entfernungsbestimmung beruhenden diagnostischen Test.
US5435970A (en) * 1989-12-18 1995-07-25 Environmental Diagnostics, Inc. Device for analysis for constituents in biological fluids
JP2618727B2 (ja) 1990-01-19 1997-06-11 富士写真フイルム株式会社 全血中の被検成分の定量方法
US5212060A (en) * 1990-04-27 1993-05-18 Genesis Labs, Inc. Dry test strip comprising a dextran barrier for excluding erythrocytes
DE4015589A1 (de) * 1990-05-15 1991-11-21 Boehringer Mannheim Gmbh Vorrichtung und deren verwendung zur abtrennung von plasma aus vollblut
US5118428A (en) * 1990-11-13 1992-06-02 Quidel Method to remove red blood cells from whole blood samples
US5877028A (en) * 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US5468648A (en) * 1991-05-29 1995-11-21 Smithkline Diagnostics, Inc. Interrupted-flow assay device
DE69220871T2 (de) * 1991-10-03 1997-11-20 Bayer Ag Vorrichtung und Verfahren zur Auftrennung und Analyse von Vollblut
US5215102A (en) * 1991-10-25 1993-06-01 La Mina Ltd. Capillary blood antigen testing apparatus
JPH05188053A (ja) 1992-01-10 1993-07-27 Sanwa Kagaku Kenkyusho Co Ltd 血液から血清又は血漿成分を分離する器具
JP2948318B2 (ja) * 1992-03-10 1999-09-13 クイデル コーポレイション 特異的結合アッセイ用の赤血球の分離方法
GR1002549B (el) * 1992-05-12 1997-01-28 Lifescan Inc. Λωρις εξετασεως με μεταφορικο μεσο δια μεταφορα ρευστου.
CA2104976A1 (en) * 1992-09-02 1994-03-03 Stephan D. Daubney Separation of plasma or serum from whole blood using a red blood cell binding component and a polymer containing multiple cationic sites
US5354692A (en) * 1992-09-08 1994-10-11 Pacific Biotech, Inc. Analyte detection device including a hydrophobic barrier for improved fluid flow
US5460974A (en) * 1992-10-13 1995-10-24 Miles Inc. Method of assaying whole blood for HDL cholesterol
WO1994018559A1 (en) * 1993-02-11 1994-08-18 Radiometer Medical A/S Asymmetric membrane sensor
US5652148A (en) * 1993-04-20 1997-07-29 Actimed Laboratories, Inc. Method and apparatus for red blood cell separation
US5397479A (en) * 1993-04-26 1995-03-14 International Remote Imaging Systems, Inc. Composition and method for enrichment of white blood cells from whole human blood
US5441698A (en) 1993-09-10 1995-08-15 Beckman Instruments, Inc. Bevel closure and device

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DK0832430T3 (da) 2006-11-20
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JP2005055451A (ja) 2005-03-03
JP3831403B2 (ja) 2006-10-11
CN1155827C (zh) 2004-06-30
US6008059A (en) 1999-12-28
CA2217210A1 (en) 1996-11-14
CN1190464A (zh) 1998-08-12
WO1996035952A1 (en) 1996-11-14
US6069014A (en) 2000-05-30
US6197598B1 (en) 2001-03-06
JPH11505327A (ja) 1999-05-18
ES2268706T3 (es) 2007-03-16
EP0832430B1 (de) 2006-07-26
DE69636389T2 (de) 2006-11-23
JP2006177970A (ja) 2006-07-06
DE69636389D1 (de) 2006-09-07

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