ATE305790T1 - Behandlung der diabetes mit thiazolidindione, insulin sekretionförderer und biguanide - Google Patents

Behandlung der diabetes mit thiazolidindione, insulin sekretionförderer und biguanide

Info

Publication number
ATE305790T1
ATE305790T1 AT98935127T AT98935127T ATE305790T1 AT E305790 T1 ATE305790 T1 AT E305790T1 AT 98935127 T AT98935127 T AT 98935127T AT 98935127 T AT98935127 T AT 98935127T AT E305790 T1 ATE305790 T1 AT E305790T1
Authority
AT
Austria
Prior art keywords
thiazolidindione
biguanide
diabetes
treatment
insulin secretion
Prior art date
Application number
AT98935127T
Other languages
German (de)
English (en)
Inventor
Robin Edwin Buckingham
Stephen Alistair Smith
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of ATE305790T1 publication Critical patent/ATE305790T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AT98935127T 1997-07-18 1998-07-16 Behandlung der diabetes mit thiazolidindione, insulin sekretionförderer und biguanide ATE305790T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9715295A GB9715295D0 (en) 1997-07-18 1997-07-18 Novel method of treatment
PCT/GB1998/002110 WO1999003477A1 (en) 1997-07-18 1998-07-16 Treatment of diabetes with thiazolidinedione, insulin secretagogue and diguanide

Publications (1)

Publication Number Publication Date
ATE305790T1 true ATE305790T1 (de) 2005-10-15

Family

ID=10816167

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98935127T ATE305790T1 (de) 1997-07-18 1998-07-16 Behandlung der diabetes mit thiazolidindione, insulin sekretionförderer und biguanide

Country Status (39)

Country Link
EP (1) EP1001783B1 (OSRAM)
JP (2) JP2001510159A (OSRAM)
KR (1) KR100671918B1 (OSRAM)
CN (1) CN1264303A (OSRAM)
AP (1) AP1352A (OSRAM)
AR (1) AR016349A1 (OSRAM)
AT (1) ATE305790T1 (OSRAM)
AU (1) AU8448898A (OSRAM)
BG (1) BG64785B1 (OSRAM)
BR (1) BR9810445A (OSRAM)
CA (1) CA2296653C (OSRAM)
CO (1) CO4940420A1 (OSRAM)
CY (1) CY1105254T1 (OSRAM)
DE (1) DE69831808T2 (OSRAM)
DK (1) DK1001783T3 (OSRAM)
DZ (1) DZ2562A1 (OSRAM)
EA (1) EA003021B1 (OSRAM)
ES (1) ES2251093T3 (OSRAM)
GB (1) GB9715295D0 (OSRAM)
HU (1) HUP0003629A3 (OSRAM)
ID (1) ID24211A (OSRAM)
IL (1) IL134046A0 (OSRAM)
IN (1) IN189275B (OSRAM)
MA (1) MA24607A1 (OSRAM)
MY (1) MY155219A (OSRAM)
NO (1) NO325727B1 (OSRAM)
NZ (2) NZ511608A (OSRAM)
OA (1) OA11279A (OSRAM)
PE (1) PE99599A1 (OSRAM)
PL (2) PL198017B1 (OSRAM)
SA (1) SA98190468B1 (OSRAM)
SI (1) SI1001783T1 (OSRAM)
SK (1) SK285484B6 (OSRAM)
TR (1) TR200000134T2 (OSRAM)
TW (1) TW505516B (OSRAM)
UA (1) UA70303C2 (OSRAM)
UY (1) UY25102A1 (OSRAM)
WO (1) WO1999003477A1 (OSRAM)
ZA (1) ZA986363B (OSRAM)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011049A (en) * 1997-02-19 2000-01-04 Warner-Lambert Company Combinations for diabetes
US6099862A (en) * 1998-08-31 2000-08-08 Andrx Corporation Oral dosage form for the controlled release of a biguanide and sulfonylurea
ES2312221T3 (es) * 1998-11-12 2009-02-16 Smithkline Beecham Plc Composicion farmaceutica para liberacion modificada de un sensibilizador de insulina y metformina.
SE9902918D0 (sv) * 1999-08-13 1999-08-13 Pharmacia & Upjohn Ab Methods for identification of compounds stimulating insulin secretion
MY125516A (en) * 1999-11-16 2006-08-30 Smithkline Beecham Plc Novel composition based on thiazolidinedione and metformin and use
WO2001035940A2 (en) * 1999-11-16 2001-05-25 Smithkline Beecham P.L.C. Pharmaceutical composition comprising a thiazolidinedione-metformin hydrochloride
FR2812547B1 (fr) * 2000-08-04 2002-10-31 Lipha Composition pharmaceutique comprenant une association metformine et derive de thiazolidinedione et son utilisation pour la preparation de medicaments destines a traiter le diabete
MXPA03006217A (es) 2001-01-12 2004-10-15 Sun Pharmaceutical Ind Ltd Sistema de administracion espaciada de farmacos.
ITFI20010126A1 (it) * 2001-07-09 2003-01-09 Molteni & C Composizioni farmaceutiche per uso orale,contenenti,in combinazione,metformina e gliclazide
AU2001273289B2 (en) * 2001-07-10 2004-10-07 Kos Life Sciences, Inc. Core formulation comprising pioglitazone hydrochloride and a biguanide
AU2002356419A1 (en) 2002-06-17 2003-12-31 Themis Laboratories Private Limited Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them
WO2004026241A2 (en) * 2002-09-20 2004-04-01 Andrx Labs Llc Multistage formulation containing a biguanide and thiazolidindione derivatives
UA80991C2 (en) 2002-10-07 2007-11-26 Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes
TWI339586B (en) 2003-10-31 2011-04-01 Takeda Chemical Industries Ltd Solid preparation comprising pioglitazone or salt thereof,glimpiride and polyoxyethylene sorbitan fatty acid ester
MXPA05010977A (es) * 2005-10-12 2007-04-11 Abdala Leopoldo Espinosa Composiciones farmaceuticas que comprenden sustancias antidiabeticas combinadas para su uso en diabetes mellitus.
KR100812538B1 (ko) * 2006-10-23 2008-03-11 한올제약주식회사 약물 제어방출형 메트포르민-글리메피리드 복합제제
CN101417130B (zh) * 2007-10-22 2010-10-06 鲁南制药集团股份有限公司 一种治疗ⅱ型糖尿病及其并发症的药物组合物
WO2019078663A2 (ko) * 2017-10-20 2019-04-25 주식회사 노브메타파마 아연염, 시클로-히스프로 및 항당뇨 약물을 유효성분으로 함유하는 당뇨병 예방 또는 치료용 약학적 조성물

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS5697277A (en) * 1980-01-07 1981-08-05 Takeda Chem Ind Ltd Thiazolidine derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
US4582839A (en) * 1984-03-21 1986-04-15 Takeda Chemical Industries, Ltd. 2,4-thiazolidinediones
CN1003445B (zh) * 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物，其制备方法和用途
JPH06779B2 (ja) * 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US4812570A (en) * 1986-07-24 1989-03-14 Takeda Chemical Industries, Ltd. Method for producing thiazolidinedione derivatives
US4791125A (en) * 1987-12-02 1988-12-13 Pfizer Inc. Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents
WO1989008651A1 (en) * 1988-03-08 1989-09-21 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
FI904414A0 (fi) * 1988-03-08 1990-09-07 Pfizer Tiazolidindion-hypoglykemiskt verkande aemnen.
WO1991007107A1 (en) * 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
JPH04210683A (ja) * 1990-12-06 1992-07-31 Terumo Corp チアゾリジン−２，４−ジオン誘導体およびこれを含有する糖尿病合併症治療薬
US5900435A (en) * 1991-08-26 1999-05-04 Pharmacia & Upjohn Company Composition, food product and uses of 3-guanidinopropionic acid
US5917052A (en) * 1994-09-28 1999-06-29 Shaman Pharmaceuticals, Inc. Hypoglycemic agent from cryptolepis
TWI238064B (en) * 1995-06-20 2005-08-21 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
WO1998057649A1 (en) * 1997-06-18 1998-12-23 Smithkline Beecham Plc Treatment of diabetes with thiazolidinedione and sulphonylurea

Also Published As

Publication number Publication date
CY1105254T1 (el) 2010-03-03
HUP0003629A3 (en) 2003-04-28
JP2005213273A (ja) 2005-08-11
SK592000A3 (en) 2000-09-12
SA98190468B1 (ar) 2007-01-20
PL198017B1 (pl) 2008-05-30
ZA986363B (en) 2000-01-17
DZ2562A1 (fr) 2003-02-15
EP1001783A1 (en) 2000-05-24
NZ501164A (en) 2001-06-29
PE99599A1 (es) 1999-12-18
BG64785B1 (bg) 2006-04-28
PL197844B1 (pl) 2008-05-30
SI1001783T1 (sl) 2006-02-28
KR100671918B1 (ko) 2007-01-22
EA003021B1 (ru) 2002-12-26
AP2000001733A0 (en) 2000-03-31
CN1264303A (zh) 2000-08-23
ID24211A (id) 2000-07-13
NZ511608A (en) 2002-12-20
UY25102A1 (es) 2000-12-29
SK285484B6 (sk) 2007-02-01
GB9715295D0 (en) 1997-09-24
BR9810445A (pt) 2000-09-05
OA11279A (en) 2003-07-31
KR20010021947A (ko) 2001-03-15
DE69831808D1 (de) 2006-02-16
NO20000228D0 (no) 2000-01-17
AU8448898A (en) 1999-02-10
EP1001783B1 (en) 2005-10-05
MY155219A (en) 2015-09-30
IN189275B (OSRAM) 2003-01-25
DE69831808T2 (de) 2006-07-06
MA24607A1 (fr) 1999-04-01
AR016349A1 (es) 2001-07-04
BG104135A (en) 2000-10-31
IL134046A0 (en) 2001-04-30
TW505516B (en) 2002-10-11
CA2296653C (en) 2007-10-02
NO20000228L (no) 2000-01-17
DK1001783T3 (da) 2006-02-06
CA2296653A1 (en) 1999-01-28
TR200000134T2 (tr) 2000-09-21
CO4940420A1 (es) 2000-07-24
EA200000139A1 (ru) 2000-06-26
UA70303C2 (uk) 2004-10-15
JP2001510159A (ja) 2001-07-31
NO325727B1 (no) 2008-07-07
WO1999003477A1 (en) 1999-01-28
HUP0003629A2 (hu) 2001-07-30
ES2251093T3 (es) 2006-04-16
HK1028550A1 (en) 2001-02-23
PL338126A1 (en) 2000-09-25
AP1352A (en) 2004-12-24

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