CY1106882T1 - Τροποποιηση βητακυτταρουλινης - Google Patents
Τροποποιηση βητακυτταρουλινηςInfo
- Publication number
- CY1106882T1 CY1106882T1 CY20071101216T CY071101216T CY1106882T1 CY 1106882 T1 CY1106882 T1 CY 1106882T1 CY 20071101216 T CY20071101216 T CY 20071101216T CY 071101216 T CY071101216 T CY 071101216T CY 1106882 T1 CY1106882 T1 CY 1106882T1
- Authority
- CY
- Cyprus
- Prior art keywords
- bitacellarine
- modification
- activity
- antigenicity
- diabetes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF] (urogastrone)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Η μεταλλαξίνη βητακυτταρουλίνη ή άλας αυτής της παρούσας εφεύρεσης είναι χρήσιμη για καλύτερο θεραπευτικό φάρμακο για διαβήτη, εφ’ όσον έχουν ανέπαφη BTC δραστικότητα και μειωμένη EGF δραστικότητα και δεν έχουν σχετικά με αντιγονικότητα προβλήματα.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP35037798 | 1998-12-09 | ||
JP5532699 | 1999-03-03 | ||
EP99959698A EP1148129B1 (en) | 1998-12-09 | 1999-12-08 | Betacellulin modification |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1106882T1 true CY1106882T1 (el) | 2012-09-26 |
Family
ID=26396224
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20071101216T CY1106882T1 (el) | 1998-12-09 | 2007-09-19 | Τροποποιηση βητακυτταρουλινης |
Country Status (11)
Country | Link |
---|---|
US (1) | US6825165B1 (el) |
EP (1) | EP1148129B1 (el) |
AT (1) | ATE368111T1 (el) |
AU (1) | AU1681100A (el) |
CA (1) | CA2353909C (el) |
CY (1) | CY1106882T1 (el) |
DE (1) | DE69936666T2 (el) |
DK (1) | DK1148129T3 (el) |
ES (1) | ES2288034T3 (el) |
PT (1) | PT1148129E (el) |
WO (1) | WO2000034478A1 (el) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008509093A (ja) * | 2004-08-06 | 2008-03-27 | ノヴォザイムズ グロペップ リミテッド | 糖尿病治療法 |
EP1890722A2 (en) * | 2005-05-27 | 2008-02-27 | Five Prime Therapeutics, Inc. | Methods of and compositions for stimulation of glucose uptake into muscle cells and treatment of diseases |
MX2023000547A (es) | 2020-07-16 | 2023-02-13 | Novartis Ag | Anticuerpos anti-betacelulina, fragmentos de los mismos, y moleculas de union multiespecificas. |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2099304T3 (es) * | 1992-02-10 | 1997-05-16 | Takeda Chemical Industries Ltd | Mitogeno de la musculatura lisa y adn que lo codifica. |
US6410506B1 (en) * | 1995-05-19 | 2002-06-25 | Human Genome Sciences, Inc. | Transforming growth factor α HII |
CN1202112A (zh) | 1995-11-09 | 1998-12-16 | 武田药品工业株式会社 | 增强胰腺功能的组合物 |
JPH10191989A (ja) * | 1996-11-12 | 1998-07-28 | Takeda Chem Ind Ltd | ベータセルリン類の製造方法 |
-
1999
- 1999-12-08 EP EP99959698A patent/EP1148129B1/en not_active Expired - Lifetime
- 1999-12-08 AT AT99959698T patent/ATE368111T1/de not_active IP Right Cessation
- 1999-12-08 WO PCT/JP1999/006873 patent/WO2000034478A1/ja active IP Right Grant
- 1999-12-08 DK DK99959698T patent/DK1148129T3/da active
- 1999-12-08 CA CA002353909A patent/CA2353909C/en not_active Expired - Fee Related
- 1999-12-08 ES ES99959698T patent/ES2288034T3/es not_active Expired - Lifetime
- 1999-12-08 DE DE69936666T patent/DE69936666T2/de not_active Expired - Lifetime
- 1999-12-08 PT PT99959698T patent/PT1148129E/pt unknown
- 1999-12-08 US US09/857,815 patent/US6825165B1/en not_active Expired - Fee Related
- 1999-12-08 AU AU16811/00A patent/AU1681100A/en not_active Abandoned
-
2007
- 2007-09-19 CY CY20071101216T patent/CY1106882T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP1148129B1 (en) | 2007-07-25 |
ES2288034T3 (es) | 2007-12-16 |
AU1681100A (en) | 2000-06-26 |
EP1148129A4 (en) | 2005-06-22 |
CA2353909A1 (en) | 2000-06-15 |
US6825165B1 (en) | 2004-11-30 |
PT1148129E (pt) | 2007-09-05 |
DK1148129T3 (da) | 2007-10-15 |
ATE368111T1 (de) | 2007-08-15 |
EP1148129A1 (en) | 2001-10-24 |
WO2000034478A1 (fr) | 2000-06-15 |
DE69936666T2 (de) | 2008-05-21 |
DE69936666D1 (de) | 2007-09-06 |
CA2353909C (en) | 2009-07-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69633679D1 (de) | Substituierte aryl-oder heteroarylamide mit retinoid-ähnlicher biologischer aktivität | |
DE69839279D1 (de) | Neue physiologisch aktive substanz sulphostin, herstellung und verwendung derselben | |
DE60121988D1 (de) | Kombinationstherapie mit antidiabetischen und antikonvulsiven mitteln | |
HU9501151D0 (en) | Substituted pyridylpyrazoles | |
DE60231295D1 (de) | R und ppar modulatoren | |
ATE232865T1 (de) | 1,4-diazabicyclo(3.2.2)nonan-4-carboxylat und carboxamidderivate, ihre herstellung und therapeutische verwendung | |
UA27911C2 (uk) | Засіб для лікування або запобігання фізіологічних розладів, які викликані надлишком тахікініну | |
ATE257844T1 (de) | Menschlicher wachstumsfaktor (hgf), verändert durch polyethylenglykol | |
DE69021383D1 (de) | Medizinisches beatmungsgerät. | |
DE69130586T2 (de) | Behandlung von Pankreaskrankheit mit 15-keto-Prostaglandin E-Derivaten | |
ITRM930291A0 (it) | Procedimento per la preparazione di biopolimeri iodurati con attivita'disinfettante e cicatrizzante, e biopolimeri iodurati cosi' ottenuti. | |
MX9101958A (es) | Inhibidores de acat de urea de aminosulfonilo | |
CY1106882T1 (el) | Τροποποιηση βητακυτταρουλινης | |
DE69003712D1 (de) | Optisch aktive Verbindungen, ihre Herstellung und Verwendung. | |
AU3401093A (en) | Therapeutic agent for threatened abortion | |
AU6309398A (en) | Agent for preventing and/or treating cachexia | |
ATE357914T1 (de) | Verwendung von 4-aminopyridin zur behandlung von peripheren neuropathien | |
DK0579939T3 (da) | Phospholipidderivater | |
DE69409961T2 (de) | Triarylethylenderivate zur therapeutischen verwendung | |
DK0673913T3 (da) | Calcium-alkalimetalcitratforbindelser samt deres anvendelse som lægemidler | |
DE59104129D1 (de) | 2,2'-Thienyl-benzothiophene, ihre Herstellung und ihre Verwendung zur Bekämpfung von Schädlingen. | |
FR2696311B1 (fr) | Ballast jetable auto-compensé. | |
IT8622051A1 (it) | Composizioni farmaceutiche ad attivita' cicatrizzante | |
BR9203896A (pt) | Convênios médicos, hospitalares e similares. | |
IT1271685B (it) | Impiego dei polidesossiribonucleotidi nelle neuropati diabetiche |