ATE299029T1 - Verfahren und zusammensetzungen zur peptidsynthese (t-20) - Google Patents

Verfahren und zusammensetzungen zur peptidsynthese (t-20)

Info

Publication number
ATE299029T1
ATE299029T1 AT99912802T AT99912802T ATE299029T1 AT E299029 T1 ATE299029 T1 AT E299029T1 AT 99912802 T AT99912802 T AT 99912802T AT 99912802 T AT99912802 T AT 99912802T AT E299029 T1 ATE299029 T1 AT E299029T1
Authority
AT
Austria
Prior art keywords
peptides
methods
present
peptide
synthesis
Prior art date
Application number
AT99912802T
Other languages
English (en)
Inventor
Myung-Chol Kang
Brian Bray
Maynard Lichty
Catherine Mader
Gene Merutka
Original Assignee
Trimeris Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/045,920 external-priority patent/US6281331B1/en
Application filed by Trimeris Inc filed Critical Trimeris Inc
Application granted granted Critical
Publication of ATE299029T1 publication Critical patent/ATE299029T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT99912802T 1998-03-23 1999-03-22 Verfahren und zusammensetzungen zur peptidsynthese (t-20) ATE299029T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/045,920 US6281331B1 (en) 1998-03-23 1998-03-23 Methods and compositions for peptide synthesis
US09/071,877 US6015881A (en) 1998-03-23 1998-05-01 Methods and compositions for peptide synthesis
PCT/US1999/006230 WO1999048513A1 (en) 1998-03-23 1999-03-22 Methods and compositions for peptide synthesis

Publications (1)

Publication Number Publication Date
ATE299029T1 true ATE299029T1 (de) 2005-07-15

Family

ID=26723345

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99912802T ATE299029T1 (de) 1998-03-23 1999-03-22 Verfahren und zusammensetzungen zur peptidsynthese (t-20)

Country Status (13)

Country Link
EP (1) EP1071442B9 (de)
JP (1) JP4602547B2 (de)
CN (1) CN100383158C (de)
AT (1) ATE299029T1 (de)
AU (1) AU751358B2 (de)
BR (1) BR9909018A (de)
CA (1) CA2324348C (de)
DE (1) DE69926061T2 (de)
DK (1) DK1071442T3 (de)
ES (1) ES2245505T3 (de)
NZ (1) NZ507083A (de)
TW (1) TWI233931B (de)
WO (1) WO1999048513A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6281331B1 (en) * 1998-03-23 2001-08-28 Trimeris, Inc. Methods and compositions for peptide synthesis
US6469136B1 (en) * 1999-07-07 2002-10-22 Trimeris, Inc. Methods and composition for peptide synthesis
CN1255548C (zh) 2001-06-15 2006-05-10 霍夫曼-拉罗奇有限公司 gp41片段的乙酰化
RU2296769C2 (ru) * 2002-07-24 2007-04-10 Ф.Хоффманн-Ля Рош Аг Пэгилированный полипептид т20
WO2005063799A2 (en) * 2003-12-31 2005-07-14 F.Hoffmann-La Roche Ag Peptide synthesis and deprotection with co-solvent
ATE410437T1 (de) 2003-12-31 2008-10-15 Hoffmann La Roche Verfahren und systeme zur rückgewinnung von peptiden
DE602004009710T2 (de) 2003-12-31 2008-08-07 F. Hoffmann-La Roche Ag Verfahren zur peptidsynthese unter verwendung einer reduzierten menge an entschützungsmittel
ES2332418T3 (es) * 2004-12-30 2010-02-04 F. Hoffmann-La Roche Ag Sintesis del peptido t-20 empleando fragmentos intermedios del peptido.
EP2013223A2 (de) 2006-05-03 2009-01-14 Mallinckrodt Inc. Zusammensetzung und verfahren zur freisetzung geschützter peptide aus einem harz
WO2009014177A1 (ja) * 2007-07-25 2009-01-29 Ajinomoto Co., Inc. ジベンゾフルベン誘導体の淘汰方法
EP2205624B1 (de) * 2007-10-27 2016-09-07 Corden Pharma Colorado, Inc. Synthese eines insulinotropen peptids mithilfe von feststoff- und flüssigphasenkombinationsverfahren
EP2222695A2 (de) * 2007-12-11 2010-09-01 F. Hoffmann-La Roche AG Synthese eines insulinotropen peptids mithilfe von feststoff- und flüssigphasenkombinationsverfahren
JP5445456B2 (ja) * 2008-08-06 2014-03-19 味の素株式会社 ジベンゾフルベンの除去方法
WO2010028122A1 (en) * 2008-09-03 2010-03-11 Scinopharm Taiwan Ltd. Process for making bivalirudin
US20110288235A1 (en) * 2008-09-03 2011-11-24 Scinopharm Taiwan Ltd. Process for the Preparation of Pramlintide
WO2011095989A2 (en) * 2010-02-04 2011-08-11 Matrix Laboratories Ltd An improved process for the preparation of enfuvirtide
PL219569B1 (pl) * 2010-02-19 2015-05-29 Peptaderm Spółka Z Ograniczoną Odpowiedzialnością Cykliczne tetrapeptydy i ich zastosowanie
CN103374054B (zh) * 2012-04-28 2014-12-24 上海第一生化药业有限公司 一步法固相合成多肽的方法
GB201315335D0 (en) 2013-08-29 2013-10-09 Of Singapore Amino diacids containing peptide modifiers
JP7415022B2 (ja) * 2020-02-05 2024-01-16 イーライ リリー アンド カンパニー 三連樹脂反応器ペプチド合成機
CN114315957B (zh) * 2021-12-30 2023-07-07 深圳瑞德林生物技术有限公司 一种多肽的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987007616A1 (en) * 1986-06-12 1987-12-17 Biogen N.V. Peptides involved in the pathogenesis of hiv infection
US4787222A (en) * 1986-11-24 1988-11-29 Novatek Medical Inc. Combination lock for blood identification system
US5444044A (en) * 1992-03-26 1995-08-22 New York Blood Center Synthetic polypeptides as inhibitors of HIV-1
AU700371B2 (en) * 1993-06-07 1999-01-07 Genentech Inc. Hiv envelope polypeptides
US6479055B1 (en) * 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
US5464933A (en) * 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission
JPH09502348A (ja) * 1993-09-11 1997-03-11 ポリムン・シエンティフィーク・イムノビオロギッシェ・フォルシュング・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 遺伝学的に分岐したｈｉｖ−１株に対する中和抗体を誘導するペプチド
WO1997029126A1 (en) * 1996-02-09 1997-08-14 F. Hoffmann-La Roche Ag Synthesis of vip analog

Also Published As

Publication number Publication date
ES2245505T3 (es) 2006-01-01
AU3109799A (en) 1999-10-18
CN1303299A (zh) 2001-07-11
EP1071442A1 (de) 2001-01-31
AU751358B2 (en) 2002-08-15
JP4602547B2 (ja) 2010-12-22
CA2324348A1 (en) 1999-09-30
EP1071442B1 (de) 2005-07-06
WO1999048513A1 (en) 1999-09-30
CA2324348C (en) 2006-03-14
DE69926061T2 (de) 2006-06-01
EP1071442A4 (de) 2002-06-05
BR9909018A (pt) 2001-10-16
TWI233931B (en) 2005-06-11
DK1071442T3 (da) 2005-10-24
EP1071442B9 (de) 2006-01-18
JP2002507576A (ja) 2002-03-12
CN100383158C (zh) 2008-04-23
NZ507083A (en) 2003-10-31
DE69926061D1 (de) 2005-08-11

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