ATE269720T1 - Verfahren zur herstellung von niedrigkristallinen calciumphosphat und verfahren zu dessen verwendung - Google Patents

Verfahren zur herstellung von niedrigkristallinen calciumphosphat und verfahren zu dessen verwendung

Info

Publication number
ATE269720T1
ATE269720T1 AT97945578T AT97945578T ATE269720T1 AT E269720 T1 ATE269720 T1 AT E269720T1 AT 97945578 T AT97945578 T AT 97945578T AT 97945578 T AT97945578 T AT 97945578T AT E269720 T1 ATE269720 T1 AT E269720T1
Authority
AT
Austria
Prior art keywords
bone
calcium phosphate
resorbable
composite
poorly crystalline
Prior art date
Application number
AT97945578T
Other languages
German (de)
English (en)
Inventor
Dosuk D Lee
Christian Rey
Maria Aiolova
Aliassghar Tofighi
Original Assignee
Etex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/729,343 external-priority patent/US20020136696A1/en
Priority claimed from US08/729,344 external-priority patent/US6117456A/en
Priority claimed from US08/732,016 external-priority patent/US6027742A/en
Application filed by Etex Corp filed Critical Etex Corp
Application granted granted Critical
Publication of ATE269720T1 publication Critical patent/ATE269720T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Composite Materials (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
AT97945578T 1996-10-16 1997-10-16 Verfahren zur herstellung von niedrigkristallinen calciumphosphat und verfahren zu dessen verwendung ATE269720T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/729,343 US20020136696A1 (en) 1995-05-19 1996-10-16 Orthopedic and dental ceramic implants
US08/729,344 US6117456A (en) 1995-05-19 1996-10-16 Methods and products related to the physical conversion of reactive amorphous calcium phosphate
US08/732,016 US6027742A (en) 1995-05-19 1996-10-16 Bioresorbable ceramic composites
PCT/US1997/018631 WO1998016268A2 (en) 1996-10-16 1997-10-16 Method of preparing a poorly crystalline calcium phosphate and methods of its use

Publications (1)

Publication Number Publication Date
ATE269720T1 true ATE269720T1 (de) 2004-07-15

Family

ID=27419129

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97945578T ATE269720T1 (de) 1996-10-16 1997-10-16 Verfahren zur herstellung von niedrigkristallinen calciumphosphat und verfahren zu dessen verwendung

Country Status (9)

Country Link
EP (1) EP0936929B1 (enExample)
JP (1) JP4781494B2 (enExample)
AT (1) ATE269720T1 (enExample)
AU (1) AU742748B2 (enExample)
CA (1) CA2270185C (enExample)
DE (1) DE69729647T2 (enExample)
DK (1) DK0936929T3 (enExample)
ES (1) ES2227719T3 (enExample)
WO (1) WO1998016268A2 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6554803B1 (en) 1997-04-02 2003-04-29 Arthur Ashman Combination syringe and aspirator for bone regeneration material and method for using the syringe
IT1299563B1 (it) * 1998-07-17 2000-03-16 Giovanni Dolci Uso odontostomatologico di materiali a base apatitica nanostrutturati
ATE228021T1 (de) 1998-09-11 2002-12-15 Gerhard Dr Schmidmaier Biologisch aktive implantate
DE69924376T2 (de) * 1999-10-21 2005-09-15 Ashman, Arthur, Westport Kombination von Spritze und Sauger für Knochenregenerationsmaterial
JP4669932B2 (ja) * 2000-05-02 2011-04-13 学校法人日本大学 生体材料用組成物及びその硬化体
JP4726281B2 (ja) * 2000-07-27 2011-07-20 テルモ株式会社 体内注入可能な組成物
WO2002034113A2 (en) * 2000-10-24 2002-05-02 Sdgi Holdings, Inc. Methods and instruments for treating pseudoarthrosis
ATE417577T1 (de) * 2000-10-24 2009-01-15 Warsaw Orthopedic Inc Vorrichtungen für die spinalfusion
JP2002226241A (ja) * 2001-01-30 2002-08-14 Mitsui Constr Co Ltd 真空凍結乾燥によるコンクリート材料のリサイクル方法
JP2002296205A (ja) * 2001-03-29 2002-10-09 Japan Tissue Engineering:Kk 培養組織の元素組成分析方法、移植適性判定方法及び品質管理方法並びに、移植適性を有する培養組織の製造方法及び移植適性を有する培養組織
US6730324B2 (en) 2001-04-20 2004-05-04 The University Of British Columbia Biofunctional hydroxyapatite coatings and microspheres for in-situ drug encapsulation
EP1448246B2 (en) 2001-11-19 2015-09-09 Scil Technology GmbH Method for producing a homogeneously coated device having osteoinductive and osteoconductive properties
US6840961B2 (en) 2001-12-21 2005-01-11 Etex Corporation Machinable preformed calcium phosphate bone substitute material implants
AU2003253049A1 (en) 2002-09-10 2004-04-30 Scil Technology Gmbh Metal implant coated under reduced oxygen concentration with osteoinductive protein
US7776594B2 (en) 2002-10-10 2010-08-17 Wright Medical Technology, Inc. Bone marrow infusion chamber and method
FR2850282B1 (fr) 2003-01-27 2007-04-06 Jerome Asius Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation
GB0307011D0 (en) 2003-03-27 2003-04-30 Regentec Ltd Porous matrix
WO2005046440A2 (en) 2003-11-07 2005-05-26 Calcitec, Inc. Spinal fusion procedure using an injectable bone substitute
DE10357460A1 (de) * 2003-12-04 2005-07-07 Friedrich-Baur-Gmbh Bioresorbierbares Material
US20050136764A1 (en) 2003-12-18 2005-06-23 Sherman Michael C. Designed composite degradation for spinal implants
US7459018B2 (en) 2005-04-08 2008-12-02 Howmedica Leibinger Inc. Injectable calcium phosphate cement
US7416602B2 (en) 2005-04-08 2008-08-26 Howmedica Leibinger, Inc. Calcium phosphate cement
DE102005022176B4 (de) * 2005-05-09 2009-06-25 Martin-Luther-Universität Halle-Wittenberg Verfahren zur Herstellung von bioresorbierbaren Verbundmaterialien und seine Verwendung als Implantatmaterial sowie bioresorbiebaren Verbundmaterialien
DE202007015205U1 (de) * 2007-10-05 2008-02-28 Epple, Matthias, Prof. Dr. Implantat
PL2244751T3 (pl) * 2008-01-09 2014-01-31 Oswestry Tissue Bank Ltd Sposób wytwarzania kompozycji do regeneracji kości
KR101692911B1 (ko) * 2008-04-15 2017-01-17 라이프 사이언스 엔터프라이즈 칼슘 포스페이트 혼합 골 시멘트를 이용한 척추의 최소 침습적 치료방법
AU2015215892B2 (en) * 2008-04-15 2017-11-30 Life Science Enterprises, Inc. Minimally invasive treatment of vertebra (mitv) using a calcium phosphate combination bone cement
EP2358651A2 (en) 2008-11-12 2011-08-24 Engqvist, Håkan Hydraulic cements, methods and products
WO2011058443A1 (en) * 2009-11-13 2011-05-19 Barralet Jake E Method and device to induce collagen biomineralisation
RU2562596C2 (ru) 2010-03-10 2015-09-10 Осс-К Аб Имплантаты и способы коррекции дефектов ткани
WO2012062360A1 (en) 2010-11-10 2012-05-18 Stryker Trauma Gmbh Polymeric bone foam composition and method
US9463046B2 (en) 2011-08-22 2016-10-11 Ossdsign Ab Implants and methods for using such implants to fill holes in bone tissue
US20130066327A1 (en) 2011-09-09 2013-03-14 Håkan Engqvist Hydraulic cement compositions with low ph methods, articles and kits
US8591645B2 (en) 2011-09-09 2013-11-26 Ossdsign Ab Hydraulic cements with optimized grain size distribution, methods, articles and kits
DE102012108320A1 (de) * 2012-09-07 2014-03-13 Aap Biomaterials Gmbh Knochenzement sowie unter Verwendung eines Knochenzements hergestellter Formkörper
EP2931325B1 (en) 2012-12-14 2020-02-19 OssDsign AB Cement-forming compositions, monetite cements, implants and methods for correcting bone defects
US10076416B2 (en) 2013-02-12 2018-09-18 Ossdsign Ab Mosaic implants, kits and methods for correcting bone defects
EP3179961B1 (en) 2014-08-14 2020-12-02 OssDsign AB Bone implants for correcting bone defects
KR101631387B1 (ko) * 2014-11-27 2016-06-16 에스케이이노베이션 주식회사 2,3-부탄디올로부터 1,3-부타디엔 및 메틸에틸케톤을 제조하는 데 사용되는 무정형 칼슘 포스페이트 촉매 및 촉매 제조 방법
JP2016209599A (ja) * 2016-05-20 2016-12-15 ライフ サイエンス エンタープライジズ インコーポレイテッド リン酸カルシウム配合骨セメントを用いる脊椎骨の最小侵襲治療（ｍｉｔｖ）
CN109663147B (zh) * 2019-02-19 2022-07-05 邢叔星 一种附着磷酸三钙缓释抗生素的peek植骨体及其制备方法
CN118806988B (zh) * 2023-04-21 2025-09-23 浙江大学 一种仿生多级球状矿化胶原支架的制备方法及应用
CN116836022B (zh) * 2023-06-25 2025-09-12 中国地质大学（武汉） 一种多功能矿物土壤调理剂及其制备方法
CN117383529A (zh) * 2023-09-12 2024-01-12 华南理工大学 一种降低无定形磷酸钙稳定性的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6117409A (ja) * 1984-07-02 1986-01-25 Meishin Toryo Kk 非晶質リン酸カルシウムの製法およびこれを主成分とする生体適応性組成物
JPS62224356A (ja) * 1986-03-26 1987-10-02 太平化学産業株式会社 生体硬組織補修材料およびその製造法
JPH01166765A (ja) * 1987-12-23 1989-06-30 Kobe Steel Ltd 代替骨およびその製造方法
US4880610A (en) * 1988-04-20 1989-11-14 Norian Corporation In situ calcium phosphate minerals--method and composition
US5037639A (en) * 1989-05-24 1991-08-06 American Dental Association Health Foundation Methods and compositions for mineralizing calcified tissues
EP0541687B1 (en) * 1990-07-27 1997-08-27 Norian Corporation Intimate mixture of calcium and phosphate sources as precursor to hydroxyapatite
JP3115642B2 (ja) * 1991-06-07 2000-12-11 日揮株式会社 人工骨材
EP0520690B1 (en) * 1991-06-26 1995-11-02 Nitta Gelatin Inc. Calcium phosphate type hardening material for repairing living hard tissue
GB9215356D0 (en) * 1992-07-20 1992-09-02 Univ Reading The Bone materials
JP3310291B2 (ja) * 1992-08-13 2002-08-05 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア 骨組織のｉｎ ｖｉｔｒｏ合成のための生物活性物質テンプレート
US5525148A (en) * 1993-09-24 1996-06-11 American Dental Association Health Foundation Self-setting calcium phosphate cements and methods for preparing and using them
US5676976A (en) * 1995-05-19 1997-10-14 Etex Corporation Synthesis of reactive amorphous calcium phosphates
US5783217A (en) * 1995-11-07 1998-07-21 Etex Corporation Low temperature calcium phosphate apatite and a method of its manufacture

Also Published As

Publication number Publication date
EP0936929B1 (en) 2004-06-23
DE69729647D1 (de) 2004-07-29
AU4674697A (en) 1998-05-11
JP2001502215A (ja) 2001-02-20
CA2270185A1 (en) 1998-04-23
JP4781494B2 (ja) 2011-09-28
DE69729647T2 (de) 2005-07-07
WO1998016268A2 (en) 1998-04-23
CA2270185C (en) 2009-01-06
WO1998016268A3 (en) 1998-07-30
DK0936929T3 (da) 2004-11-08
ES2227719T3 (es) 2005-04-01
EP0936929A2 (en) 1999-08-25
AU742748B2 (en) 2002-01-10

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