ATE250072T1 - Verfahren für die racemisation der atropisomerischen bis (phosphinoxid) verbindungen - Google Patents
Verfahren für die racemisation der atropisomerischen bis (phosphinoxid) verbindungenInfo
- Publication number
- ATE250072T1 ATE250072T1 AT00114219T AT00114219T ATE250072T1 AT E250072 T1 ATE250072 T1 AT E250072T1 AT 00114219 T AT00114219 T AT 00114219T AT 00114219 T AT00114219 T AT 00114219T AT E250072 T1 ATE250072 T1 AT E250072T1
- Authority
- AT
- Austria
- Prior art keywords
- racemization
- heating
- compounds
- phosphine oxide
- complexes
- Prior art date
Links
- 230000006340 racemization Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- MPQXHAGKBWFSNV-UHFFFAOYSA-N oxidophosphanium Chemical class [PH3]=O MPQXHAGKBWFSNV-UHFFFAOYSA-N 0.000 title abstract 2
- 238000010438 heat treatment Methods 0.000 abstract 3
- 230000003287 optical effect Effects 0.000 abstract 2
- 229910052782 aluminium Inorganic materials 0.000 abstract 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 239000000155 melt Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- 229910052723 transition metal Inorganic materials 0.000 abstract 1
- 150000003624 transition metals Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/53—Organo-phosphine oxides; Organo-phosphine thioxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/53—Organo-phosphine oxides; Organo-phosphine thioxides
- C07F9/5329—Polyphosphine oxides or thioxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/505—Preparation; Separation; Purification; Stabilisation
- C07F9/5054—Preparation; Separation; Purification; Stabilisation by a process in which the phosphorus atom is not involved
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99113306 | 1999-07-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE250072T1 true ATE250072T1 (de) | 2003-10-15 |
Family
ID=8238553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00114219T ATE250072T1 (de) | 1999-07-09 | 2000-07-03 | Verfahren für die racemisation der atropisomerischen bis (phosphinoxid) verbindungen |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6288280B1 (de) |
| EP (1) | EP1067133B1 (de) |
| JP (1) | JP3688563B2 (de) |
| KR (1) | KR100385800B1 (de) |
| CN (1) | CN1163499C (de) |
| AT (1) | ATE250072T1 (de) |
| BR (2) | BRPI0002650B8 (de) |
| CA (1) | CA2313338C (de) |
| DE (1) | DE60005257T2 (de) |
| DK (1) | DK1067133T3 (de) |
| ES (1) | ES2204411T3 (de) |
| JO (1) | JO2284B1 (de) |
| MX (1) | MXPA00006740A (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003273926A1 (en) * | 2002-10-01 | 2004-04-23 | Dieter Arlt | Isomerisation of chiral homogeneous o,o'-dihydroxybiphenyl derivatives |
| JP4375997B2 (ja) * | 2003-05-19 | 2009-12-02 | 三洋電機株式会社 | 有機化合物の製造方法及び製造装置 |
| JP5009613B2 (ja) * | 2003-06-13 | 2012-08-22 | ベーリンガー・インゲルハイム・インテルナツィオナール・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 不斉合成における使用のためのキラル配位子 |
| CN100497297C (zh) * | 2005-01-24 | 2009-06-10 | 南京大学 | 光学活性氨基酸或其盐的微波消旋方法 |
| CN108303385B (zh) * | 2017-10-21 | 2021-12-24 | 聊城鲁西多元醇新材料科技有限公司 | 一种测定双膦配体铑催化剂中铑含量的方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3204667B2 (ja) | 1991-03-15 | 2001-09-04 | エフ・ホフマン―ラ ロシユ アーゲー | キラルなホスフイン |
| US5334766A (en) * | 1991-04-29 | 1994-08-02 | Hoffmann-La Roche Inc. | Process for the resolution of racemic diphosphine oxides |
| EP0579797B1 (de) | 1992-01-31 | 1999-04-21 | F. Hoffmann-La Roche Ag | Diphosphinliganden |
| JP3898220B2 (ja) * | 1994-09-23 | 2007-03-28 | ダーウィン・ディスカバリー・リミテッド | レボブピバカインおよびその類似体の製造に使用するラセミ化と不斉変換法 |
| JP3148136B2 (ja) * | 1996-12-26 | 2001-03-19 | 高砂香料工業株式会社 | 新規なキラルジホスフィン化合物、その製造中間体、該ジホス フィン化合物を配位子とする遷移金属錯体並びに該錯体を含む 不斉水素化触媒 |
| US6162929A (en) * | 1997-12-23 | 2000-12-19 | Hoffmann-La Roche Inc. | Process for the manufacture of bisphosphine oxide and bisphosphonate compounds |
-
2000
- 2000-06-15 US US09/594,643 patent/US6288280B1/en not_active Expired - Lifetime
- 2000-07-03 DE DE60005257T patent/DE60005257T2/de not_active Expired - Lifetime
- 2000-07-03 ES ES00114219T patent/ES2204411T3/es not_active Expired - Lifetime
- 2000-07-03 DK DK00114219T patent/DK1067133T3/da active
- 2000-07-03 EP EP00114219A patent/EP1067133B1/de not_active Expired - Lifetime
- 2000-07-03 AT AT00114219T patent/ATE250072T1/de active
- 2000-07-04 CA CA002313338A patent/CA2313338C/en not_active Expired - Lifetime
- 2000-07-05 JP JP2000203499A patent/JP3688563B2/ja not_active Expired - Lifetime
- 2000-07-06 JO JO2000111A patent/JO2284B1/en active
- 2000-07-07 MX MXPA00006740A patent/MXPA00006740A/es active IP Right Grant
- 2000-07-07 CN CNB001204173A patent/CN1163499C/zh not_active Expired - Lifetime
- 2000-07-07 BR BRPI0002650A patent/BRPI0002650B8/pt unknown
- 2000-07-07 KR KR10-2000-0038763A patent/KR100385800B1/ko active IP Right Grant
- 2000-07-07 BR BRPI0002650-6A patent/BR0002650B1/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BR0002650A (pt) | 2001-03-13 |
| BRPI0002650B8 (pt) | 2019-02-26 |
| CA2313338C (en) | 2008-12-30 |
| DE60005257T2 (de) | 2004-07-01 |
| CN1163499C (zh) | 2004-08-25 |
| ES2204411T3 (es) | 2004-05-01 |
| US6288280B1 (en) | 2001-09-11 |
| KR100385800B1 (ko) | 2003-06-02 |
| DK1067133T3 (da) | 2004-01-19 |
| DE60005257D1 (de) | 2003-10-23 |
| CA2313338A1 (en) | 2001-01-09 |
| JO2284B1 (en) | 2005-09-12 |
| EP1067133A1 (de) | 2001-01-10 |
| KR20010049732A (ko) | 2001-06-15 |
| EP1067133B1 (de) | 2003-09-17 |
| MXPA00006740A (es) | 2005-04-14 |
| JP2001039993A (ja) | 2001-02-13 |
| CN1281860A (zh) | 2001-01-31 |
| JP3688563B2 (ja) | 2005-08-31 |
| BR0002650B1 (pt) | 2011-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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