ATE244013T1 - Phosphatbindende polymerzubereitungen - Google Patents

Phosphatbindende polymerzubereitungen

Info

Publication number
ATE244013T1
ATE244013T1 AT98911187T AT98911187T ATE244013T1 AT E244013 T1 ATE244013 T1 AT E244013T1 AT 98911187 T AT98911187 T AT 98911187T AT 98911187 T AT98911187 T AT 98911187T AT E244013 T1 ATE244013 T1 AT E244013T1
Authority
AT
Austria
Prior art keywords
phosphate
binding polymer
particle size
less
polymer preparations
Prior art date
Application number
AT98911187T
Other languages
German (de)
English (en)
Inventor
Katsuya Matsuda
Ryuji Kubota
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE244013T1 publication Critical patent/ATE244013T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
AT98911187T 1997-04-04 1998-04-03 Phosphatbindende polymerzubereitungen ATE244013T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8658197 1997-04-04
PCT/JP1998/001536 WO1998044933A1 (en) 1997-04-04 1998-04-03 Phosphate-binding polymer preparations

Publications (1)

Publication Number Publication Date
ATE244013T1 true ATE244013T1 (de) 2003-07-15

Family

ID=13890981

Family Applications (2)

Application Number Title Priority Date Filing Date
AT98911187T ATE244013T1 (de) 1997-04-04 1998-04-03 Phosphatbindende polymerzubereitungen
AT02025683T ATE364377T1 (de) 1997-04-04 1998-04-03 Tablette, umfassend ein phosphatbindendes polymer

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT02025683T ATE364377T1 (de) 1997-04-04 1998-04-03 Tablette, umfassend ein phosphatbindendes polymer

Country Status (15)

Country Link
US (2) US6383518B1 (cg-RX-API-DMAC7.html)
EP (2) EP1304104B1 (cg-RX-API-DMAC7.html)
JP (2) JP2009173687A (cg-RX-API-DMAC7.html)
KR (1) KR100456202B1 (cg-RX-API-DMAC7.html)
CN (1) CN1180782C (cg-RX-API-DMAC7.html)
AT (2) ATE244013T1 (cg-RX-API-DMAC7.html)
AU (1) AU726142B2 (cg-RX-API-DMAC7.html)
CA (1) CA2286003C (cg-RX-API-DMAC7.html)
CY (1) CY1106823T1 (cg-RX-API-DMAC7.html)
DE (2) DE69837945T2 (cg-RX-API-DMAC7.html)
DK (1) DK1304104T3 (cg-RX-API-DMAC7.html)
ES (2) ES2201463T3 (cg-RX-API-DMAC7.html)
PT (1) PT1304104E (cg-RX-API-DMAC7.html)
TW (1) TW592727B (cg-RX-API-DMAC7.html)
WO (1) WO1998044933A1 (cg-RX-API-DMAC7.html)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9720061D0 (en) 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
JP3718341B2 (ja) 1998-05-12 2005-11-24 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロースとその製造方法
TW568788B (en) 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
DE60017285T2 (de) * 1999-10-19 2005-12-08 Genzyme Corp., Cambridge Direktkomprimierter tablettenkern auf polymerbasis
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US6680069B1 (en) 1999-11-09 2004-01-20 Shin-Etsu Chemical Co., Ltd. Low-substituted hydroxypropyl cellulose and process for manufacturing the same
JP3552160B2 (ja) 2000-01-14 2004-08-11 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロース粒子の形成方法
WO2002066543A1 (en) 2001-02-16 2002-08-29 Genzyme Corporation Method of drying a material having a cohesive phase
WO2002085379A1 (en) * 2001-04-18 2002-10-31 Geltex Pharmaceuticals, Inc. Method for improving vascular access in patients with vascular shunts
DK1392331T3 (da) 2001-04-18 2008-06-23 Genzyme Corp Anvendelse af colesevelam eller sevelamer, hydrogenchlorid til sænkning af serumglucoseniveauet
CN1290515C (zh) 2001-04-18 2006-12-20 基酶有限公司 低盐含量的聚烯丙胺
FR2827771B1 (fr) * 2001-07-25 2003-10-24 Apis Spheromont Formulation et procede de preparation de spheroides pouvant etre fortement titres et a dispersion rapide
US6600011B2 (en) 2001-10-09 2003-07-29 Genzyme Corporation Process for purification and drying of polymer hydrogels
TWI231760B (en) * 2001-12-20 2005-05-01 Chugai Pharmaceutical Co Ltd Coated lozenge and manufacturing method thereof
US7767768B2 (en) 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7335795B2 (en) * 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7459502B2 (en) 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7385012B2 (en) 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7449605B2 (en) 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7608674B2 (en) 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
EP1869090A1 (en) * 2005-03-16 2007-12-26 Council Of Scientific And Industrial Research An improved process for the preparation of crosslinked polyallylamine polymer.
EP1951266A2 (en) * 2005-09-02 2008-08-06 Genzyme Corporation Method for removing phosphate and polymer used therefore
DK1924246T3 (en) 2005-09-15 2016-01-18 Genzyme Corp PORTION LETTER DEFINITION OF amine polymers
GB0601899D0 (en) * 2006-01-31 2006-03-08 Ineos Silicas Ltd Compositions
MY157620A (en) * 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
ES2320265T3 (es) * 2006-02-14 2009-05-20 Teva Pharmaceutical Industries, Ltd. Formulaciones farmaceuticas de polimeros amino alifaticos y procedimientos para su preparacion.
CN101404982A (zh) 2006-02-14 2009-04-08 特瓦制药工业有限公司 脂族胺聚合物的药物制剂和它们的制造方法
EP2016114A2 (en) * 2006-05-05 2009-01-21 Genzyme Corporation Amine condensation polymers as phosphate sequestrants
WO2008011047A2 (en) * 2006-07-18 2008-01-24 Genzyme Corporation Amine dendrimers
US7964182B2 (en) 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
CA2749074A1 (en) * 2006-09-01 2008-05-29 Usv Limited Process for the preparation of sevelamer hydrochloride and formulation thereof
EP2066293A2 (en) 2006-09-29 2009-06-10 Genzyme Corporation Amide dendrimer compositions
JP2010513271A (ja) 2006-12-14 2010-04-30 ゲンズイメ コーポレーション アミド−アミンポリマー組成物
WO2008103368A1 (en) * 2007-02-23 2008-08-28 Genzyme Corporation Amine polymer compositions
JP2010520285A (ja) * 2007-03-08 2010-06-10 ゲンズイメ コーポレーション スルホンポリマー組成物
WO2008133954A1 (en) * 2007-04-27 2008-11-06 Genzyme Corporation Amido-amine dendrimer compositions
GB0714670D0 (en) 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
WO2009034540A1 (en) * 2007-09-11 2009-03-19 Ranbaxy Laboratories Limited Pharmaceutical composition of sevelamer
GB0720220D0 (en) 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
WO2009078958A1 (en) * 2007-12-14 2009-06-25 Genzyme Corporation Coated pharmaceutical compositions
WO2009154747A1 (en) * 2008-06-20 2009-12-23 Genzyme Corporation Pharmaceutical compositions
DE102008030046A1 (de) 2008-06-25 2009-12-31 Ratiopharm Gmbh Kompaktiertes Polyallylamin-Polymer
BRPI1006969A2 (pt) 2009-01-22 2016-04-12 Usv Ltd composições farmacêuticas compreendendo polímero de ligação a fosfato
US20100330175A1 (en) * 2009-06-24 2010-12-30 Jobdevairakkam Christopher N Cross-linked polyallylamine tablet core
WO2010149794A2 (en) 2009-06-26 2010-12-29 Combino Pharm, S.L. Novel pharmaceutical composition comprising poly (allylamin-co-n,n'-diallyl- 1,3-diamino-2-hydroxypropane)
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
DK2490675T3 (en) * 2009-10-22 2019-04-29 Synthon Bv Pharmaceutical compositions with sevelamer
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition
EP2545907A1 (en) 2011-07-15 2013-01-16 Combino Pharm, S.L. Aqueous wet granulation process for cross-linked polyallylamine polymers
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
WO2016135065A1 (en) * 2015-02-23 2016-09-01 Amneal Pharmaceuticals Company Gmbh Process for granulating sevelamer carbonate
TWI757398B (zh) 2016-12-28 2022-03-11 日商富士軟片股份有限公司 含氮原子的聚合物或其鹽的乳化液、其製造方法、及粒子的製造方法
CN111225674A (zh) 2017-10-16 2020-06-02 富士胶片株式会社 高磷血症治疗剂
TW201922268A (zh) * 2017-10-16 2019-06-16 日商富士軟片股份有限公司 高磷血症治療劑及粒子
JP2019182818A (ja) * 2018-04-17 2019-10-24 ライオン株式会社 舌苔除去用の口腔内崩壊錠及び舌苔除去方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6090243A (ja) 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
US4631305A (en) 1985-03-22 1986-12-23 The Upjohn Company Polymeric material as a disintegrant in a compressed tablet
DE3776116D1 (de) * 1986-12-30 1992-02-27 American Cyanamid Co Zusammensetzung die ein polycarbophil enthaelt.
US4956182A (en) * 1989-03-16 1990-09-11 Bristol-Myers Company Direct compression cholestyramine tablet and solvent-free coating therefor
JPH02286621A (ja) * 1989-04-26 1990-11-26 Mitsubishi Kasei Corp 経口コレステロール低下剤
JPH0413627A (ja) * 1990-04-27 1992-01-17 Mitsubishi Kasei Corp 経口コレステロール低下剤
JP2609022B2 (ja) * 1990-11-29 1997-05-14 北陸製薬株式会社 ポリカルボフィルカルシウム含有製剤
JPH06157325A (ja) * 1992-11-30 1994-06-03 Mitsubishi Kasei Corp 経口コレステロール低下剤
TW272942B (cg-RX-API-DMAC7.html) 1993-02-10 1996-03-21 Takeda Pharm Industry Co Ltd
US5496545A (en) 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5667775A (en) * 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
WO1996021454A1 (en) * 1995-01-12 1996-07-18 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
JP3836893B2 (ja) 1995-01-24 2006-10-25 アボットジャパン株式会社 ポリカルボフィルカルシウム含有製剤
TW438608B (en) * 1995-08-02 2001-06-07 Hisamitsu Pharmaceutical Co A tablet containing anion exchange resin
JP3389493B2 (ja) * 1997-04-04 2003-03-24 中外製薬株式会社 リン酸結合性ポリマー製剤

Also Published As

Publication number Publication date
CA2286003A1 (en) 1998-10-15
EP1304104A3 (en) 2003-11-12
JP2009173687A (ja) 2009-08-06
EP0997148A4 (en) 2000-05-03
AU726142B2 (en) 2000-11-02
US6383518B1 (en) 2002-05-07
DE69837945T2 (de) 2008-02-21
CN1254287A (zh) 2000-05-24
EP1304104A2 (en) 2003-04-23
JP2013010803A (ja) 2013-01-17
ES2287215T3 (es) 2007-12-16
EP0997148A1 (en) 2000-05-03
HK1055387A1 (en) 2004-01-09
KR20010005980A (ko) 2001-01-15
DE69816082D1 (de) 2003-08-07
ATE364377T1 (de) 2007-07-15
CY1106823T1 (el) 2012-05-23
WO1998044933A1 (en) 1998-10-15
CN1180782C (zh) 2004-12-22
EP1304104B1 (en) 2007-06-13
HK1027506A1 (en) 2001-01-19
AU6522398A (en) 1998-10-30
CA2286003C (en) 2007-06-05
DE69816082T2 (de) 2004-04-15
DK1304104T3 (da) 2007-07-16
PT1304104E (pt) 2007-07-27
EP0997148B1 (en) 2003-07-02
ES2201463T3 (es) 2004-03-16
DE69837945D1 (de) 2007-07-26
US6696087B2 (en) 2004-02-24
US20020122786A1 (en) 2002-09-05
TW592727B (en) 2004-06-21
KR100456202B1 (ko) 2004-11-09
JP5681156B2 (ja) 2015-03-04

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