ATE239479T1 - Endothelin antagonist und betarezeptorenblocker als kombinationspräparate - Google Patents
Endothelin antagonist und betarezeptorenblocker als kombinationspräparateInfo
- Publication number
- ATE239479T1 ATE239479T1 AT98945323T AT98945323T ATE239479T1 AT E239479 T1 ATE239479 T1 AT E239479T1 AT 98945323 T AT98945323 T AT 98945323T AT 98945323 T AT98945323 T AT 98945323T AT E239479 T1 ATE239479 T1 AT E239479T1
- Authority
- AT
- Austria
- Prior art keywords
- endothelin antagonist
- combination preparations
- blockers
- betareceptor
- combination
- Prior art date
Links
- 239000002876 beta blocker Substances 0.000 title abstract 2
- 239000002308 endothelin receptor antagonist Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 102000002045 Endothelin Human genes 0.000 abstract 1
- 108050009340 Endothelin Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- ZUBDGKVDJUIMQQ-UBFCDGJISA-N endothelin-1 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(O)=O)NC(=O)[C@H]1NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@@H](CC=2C=CC(O)=CC=2)NC(=O)[C@H](C(C)C)NC(=O)[C@H]2CSSC[C@@H](C(N[C@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)CSSC1)C1=CNC=N1 ZUBDGKVDJUIMQQ-UBFCDGJISA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19743143A DE19743143A1 (de) | 1997-09-30 | 1997-09-30 | Pharmazeutische Kombinationspräparate |
| PCT/EP1998/005772 WO1999016444A1 (de) | 1997-09-30 | 1998-09-10 | Endothelin-antagonist und betarezeptorenblocker als kombinationspräparate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE239479T1 true ATE239479T1 (de) | 2003-05-15 |
Family
ID=7844115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98945323T ATE239479T1 (de) | 1997-09-30 | 1998-09-10 | Endothelin antagonist und betarezeptorenblocker als kombinationspräparate |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6352992B1 (cs) |
| EP (1) | EP1019055B1 (cs) |
| JP (1) | JP4608093B2 (cs) |
| KR (1) | KR100623122B1 (cs) |
| CN (1) | CN1149087C (cs) |
| AT (1) | ATE239479T1 (cs) |
| AU (1) | AU739860B2 (cs) |
| BR (1) | BR9812404A (cs) |
| CA (1) | CA2304698C (cs) |
| CZ (1) | CZ298745B6 (cs) |
| DE (2) | DE19743143A1 (cs) |
| ES (1) | ES2199461T3 (cs) |
| HU (1) | HU226745B1 (cs) |
| NO (1) | NO319048B1 (cs) |
| RU (1) | RU2213577C2 (cs) |
| WO (1) | WO1999016444A1 (cs) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19533023B4 (de) * | 1994-10-14 | 2007-05-16 | Basf Ag | Neue Carbonsäurederivate, ihre Herstellung und Verwendung |
| DK1243262T3 (da) | 2001-03-20 | 2006-10-02 | Sanol Arznei Schwarz Gmbh | Hidtil ukendt anvendelse af en peptidklasse af forbindelser til behandling af ikke-neuropatiske, inflammatoriske smerter |
| EP1243263B1 (en) | 2001-03-21 | 2002-11-27 | Schwarz Pharma Ag | Novel use of a peptide class of compound for treating allodynia or other different types of chronic or phantom pain |
| CN1950101B (zh) | 2004-04-16 | 2011-03-30 | 舒沃茨药物股份公司 | 肽化合物用于预防和治疗慢性头痛的用途 |
| DE602005021970D1 (de) | 2004-08-27 | 2010-08-05 | Ucb Pharma Gmbh | Verwendung von peptidverbindungen zur behandlung von schmerzen durch knochenkrebs, chemotherapie- und nucleosid-bedingten schmerzen |
| AU2005284822B2 (en) * | 2004-09-14 | 2011-03-24 | Regents Of The University Of Colorado | Method for treatment with bucindolol based on genetic targeting |
| US20070196510A1 (en) * | 2006-02-17 | 2007-08-23 | Gerber Michael J | Method for treating resistant hypertension |
| WO2007144195A2 (en) | 2006-06-15 | 2007-12-21 | Schwarz Pharma Ag | Pharmaceutical composition with synergistic anticonvulsant effect |
| CA2904447C (en) | 2007-08-22 | 2017-01-03 | Abbvie Deutschland Gmbh & Co Kg | Therapy for complications of diabetes |
| CN104887645B (zh) * | 2015-06-15 | 2016-12-14 | 吉林万通药业集团梅河药业股份有限公司 | 阿莫西林胶囊及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4786441A (en) * | 1987-08-24 | 1988-11-22 | International Business Machines Corporation | Preparation of iodonium and sulfonium triflates |
| SE8704081D0 (sv) * | 1987-10-21 | 1987-10-21 | Haessle Ab | A new prohylactic method |
| ATE189217T1 (de) * | 1993-03-19 | 2000-02-15 | Merck & Co Inc | Phenoxyphenylessigsäurederivate |
| EP0750608A1 (en) * | 1994-01-28 | 1997-01-02 | Cal International Limited | Pharmaceutical product comprising a salicylate of an esterifiable beta-blocker |
| DE4411225A1 (de) * | 1994-03-31 | 1995-10-05 | Basf Ag | Verwendung von Carbonsäurederivaten als Arzneimittel |
| DE19533023B4 (de) * | 1994-10-14 | 2007-05-16 | Basf Ag | Neue Carbonsäurederivate, ihre Herstellung und Verwendung |
| CA2206119C (en) * | 1994-12-12 | 2008-05-13 | Omeros Medical Systems, Inc. | Irrigation solution and method for inhibition of pain, inflammation and spasm |
| HUP9801938A3 (en) | 1995-01-27 | 1999-10-28 | Rhone Poulenc Rorer Ltd West M | Substituted phenyl compounds as endothelin antagonists, process for producing and use thereof |
| DE19636046A1 (de) * | 1996-09-05 | 1998-03-12 | Basf Ag | Neue Carbonsäurederivate, ihre Herstellung und Verwendung als gemischte ET¶A¶/ET¶B¶-Rezeptorantagonisten |
| DE19652374A1 (de) * | 1996-12-04 | 1998-06-10 | Schering Ag | Verwendung von Endothelin-Konjugaten in der Therapie, neue Endothelin-Konjugate, diese enthaltende Mittel, sowie Verfahren zu deren Herstellung |
| US6448248B1 (en) * | 1996-12-18 | 2002-09-10 | Abbott Laboratories | Heterocyclic carboxylic acid derivatives, the production and use thereof as endothelin receptor antagonists |
-
1997
- 1997-09-30 DE DE19743143A patent/DE19743143A1/de not_active Withdrawn
-
1998
- 1998-09-10 DE DE59808297T patent/DE59808297D1/de not_active Expired - Lifetime
- 1998-09-10 HU HU0004590A patent/HU226745B1/hu not_active IP Right Cessation
- 1998-09-10 AU AU92672/98A patent/AU739860B2/en not_active Ceased
- 1998-09-10 CZ CZ20001081A patent/CZ298745B6/cs not_active IP Right Cessation
- 1998-09-10 BR BR9812404-8A patent/BR9812404A/pt active Search and Examination
- 1998-09-10 US US09/508,989 patent/US6352992B1/en not_active Expired - Lifetime
- 1998-09-10 JP JP2000513580A patent/JP4608093B2/ja not_active Expired - Fee Related
- 1998-09-10 AT AT98945323T patent/ATE239479T1/de active
- 1998-09-10 EP EP98945323A patent/EP1019055B1/de not_active Expired - Lifetime
- 1998-09-10 CN CNB988097273A patent/CN1149087C/zh not_active Expired - Fee Related
- 1998-09-10 WO PCT/EP1998/005772 patent/WO1999016444A1/de active IP Right Grant
- 1998-09-10 KR KR1020007003346A patent/KR100623122B1/ko not_active Expired - Fee Related
- 1998-09-10 RU RU2000111500/14A patent/RU2213577C2/ru not_active IP Right Cessation
- 1998-09-10 ES ES98945323T patent/ES2199461T3/es not_active Expired - Lifetime
- 1998-09-10 CA CA002304698A patent/CA2304698C/en not_active Expired - Fee Related
-
2000
- 2000-03-29 NO NO20001634A patent/NO319048B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0004590A3 (en) | 2002-01-28 |
| DE59808297D1 (de) | 2003-06-12 |
| NO20001634D0 (no) | 2000-03-29 |
| ES2199461T3 (es) | 2004-02-16 |
| US6352992B1 (en) | 2002-03-05 |
| EP1019055A1 (de) | 2000-07-19 |
| CZ298745B6 (cs) | 2008-01-16 |
| CZ20001081A3 (en) | 2001-05-16 |
| KR20010015650A (ko) | 2001-02-26 |
| NO319048B1 (no) | 2005-06-06 |
| CA2304698C (en) | 2008-02-19 |
| JP4608093B2 (ja) | 2011-01-05 |
| WO1999016444A1 (de) | 1999-04-08 |
| HUP0004590A2 (hu) | 2001-11-28 |
| NO20001634L (no) | 2000-03-29 |
| EP1019055B1 (de) | 2003-05-07 |
| JP2001517703A (ja) | 2001-10-09 |
| CA2304698A1 (en) | 1999-04-08 |
| DE19743143A1 (de) | 1999-04-01 |
| CN1272786A (zh) | 2000-11-08 |
| AU739860B2 (en) | 2001-10-25 |
| HK1032355A1 (en) | 2001-07-20 |
| KR100623122B1 (ko) | 2006-09-12 |
| BR9812404A (pt) | 2000-09-19 |
| AU9267298A (en) | 1999-04-23 |
| RU2213577C2 (ru) | 2003-10-10 |
| CN1149087C (zh) | 2004-05-12 |
| HU226745B1 (en) | 2009-09-28 |
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