ATE239016T1 - Verfahren zur herstellung von einer nicht- kristallinen wasswerfreien form von paroxetin hydrochlorid - Google Patents
Verfahren zur herstellung von einer nicht- kristallinen wasswerfreien form von paroxetin hydrochloridInfo
- Publication number
- ATE239016T1 ATE239016T1 AT99940290T AT99940290T ATE239016T1 AT E239016 T1 ATE239016 T1 AT E239016T1 AT 99940290 T AT99940290 T AT 99940290T AT 99940290 T AT99940290 T AT 99940290T AT E239016 T1 ATE239016 T1 AT E239016T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- anhydrous form
- paroxetine hydrochloride
- crystalline anhydrous
- crystalline
- Prior art date
Links
- AHOUBRCZNHFOSL-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine Chemical compound C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 229960005183 paroxetine hydrochloride Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9817196.0A GB9817196D0 (en) | 1998-08-07 | 1998-08-07 | Novel process |
| GBGB9828777.4A GB9828777D0 (en) | 1998-12-29 | 1998-12-29 | Novel compounds |
| PCT/GB1999/002592 WO2000008017A1 (en) | 1998-08-07 | 1999-08-06 | Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE239016T1 true ATE239016T1 (de) | 2003-05-15 |
Family
ID=26314179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99940290T ATE239016T1 (de) | 1998-08-07 | 1999-08-06 | Verfahren zur herstellung von einer nicht- kristallinen wasswerfreien form von paroxetin hydrochlorid |
Country Status (23)
| Country | Link |
|---|---|
| EP (2) | EP1321465A3 (de) |
| JP (1) | JP2002522434A (de) |
| KR (1) | KR20010072323A (de) |
| CN (1) | CN1321155A (de) |
| AP (2) | AP0102072A0 (de) |
| AT (1) | ATE239016T1 (de) |
| AU (1) | AU5428999A (de) |
| BG (1) | BG105310A (de) |
| BR (1) | BR9912858A (de) |
| CA (1) | CA2339857A1 (de) |
| DE (1) | DE69907467T2 (de) |
| DK (1) | DK1100796T3 (de) |
| EA (1) | EA200100221A1 (de) |
| ES (1) | ES2198940T3 (de) |
| HU (1) | HUP0105466A3 (de) |
| ID (1) | ID27914A (de) |
| IL (1) | IL141286A0 (de) |
| NO (1) | NO20010629L (de) |
| PL (1) | PL345885A1 (de) |
| PT (1) | PT1100796E (de) |
| SK (1) | SK1972001A3 (de) |
| TR (1) | TR200100444T2 (de) |
| WO (1) | WO2000008017A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1384720A1 (de) * | 1996-06-13 | 2004-01-28 | SUMIKA FINE CHEMICALS Co., Ltd. | Verfahren zur Trocknung von Paroxetinhydrochlorid |
| JP3796351B2 (ja) * | 1998-04-13 | 2006-07-12 | 住友化学株式会社 | パロキセチン塩酸塩無水和物の乾燥方法 |
| GB9923446D0 (en) * | 1999-10-04 | 1999-12-08 | Smithkline Beecham Plc | Novel process |
| WO2002040508A2 (en) * | 2000-11-17 | 2002-05-23 | Eli Lilly And Company | Lactam dipeptide and its use in inhibiting beta-amyloid peptide release |
| WO2004035052A1 (ja) | 2002-10-16 | 2004-04-29 | Takeda Pharmaceutical Company Limited | 安定な固形製剤 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| DE3688827T2 (de) * | 1985-10-25 | 1994-03-31 | Beecham Group Plc | Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel. |
| SK283608B6 (sk) * | 1995-02-06 | 2003-10-07 | Smithkline Beecham Plc | Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie |
| AU730532B2 (en) * | 1997-01-15 | 2001-03-08 | Smithkline Beecham Plc | Paroxetine compositions |
| JP3796351B2 (ja) * | 1998-04-13 | 2006-07-12 | 住友化学株式会社 | パロキセチン塩酸塩無水和物の乾燥方法 |
-
1999
- 1999-08-06 AT AT99940290T patent/ATE239016T1/de not_active IP Right Cessation
- 1999-08-06 SK SK197-2001A patent/SK1972001A3/sk unknown
- 1999-08-06 HU HU0105466A patent/HUP0105466A3/hu unknown
- 1999-08-06 CA CA002339857A patent/CA2339857A1/en not_active Abandoned
- 1999-08-06 WO PCT/GB1999/002592 patent/WO2000008017A1/en not_active Ceased
- 1999-08-06 AP APAP/P/2001/002072A patent/AP0102072A0/en unknown
- 1999-08-06 DK DK99940290T patent/DK1100796T3/da active
- 1999-08-06 CN CN99811643A patent/CN1321155A/zh active Pending
- 1999-08-06 EP EP02080022A patent/EP1321465A3/de not_active Withdrawn
- 1999-08-06 BR BR9912858-6A patent/BR9912858A/pt not_active Application Discontinuation
- 1999-08-06 PT PT99940290T patent/PT1100796E/pt unknown
- 1999-08-06 ES ES99940290T patent/ES2198940T3/es not_active Expired - Lifetime
- 1999-08-06 AU AU54289/99A patent/AU5428999A/en not_active Abandoned
- 1999-08-06 AP AP2001002072A patent/AP2001002072A0/xx unknown
- 1999-08-06 DE DE69907467T patent/DE69907467T2/de not_active Expired - Fee Related
- 1999-08-06 EP EP99940290A patent/EP1100796B1/de not_active Expired - Lifetime
- 1999-08-06 TR TR2001/00444T patent/TR200100444T2/xx unknown
- 1999-08-06 IL IL14128699A patent/IL141286A0/xx unknown
- 1999-08-06 ID IDW20010296A patent/ID27914A/id unknown
- 1999-08-06 PL PL99345885A patent/PL345885A1/xx not_active Application Discontinuation
- 1999-08-06 JP JP2000563650A patent/JP2002522434A/ja active Pending
- 1999-08-06 EA EA200100221A patent/EA200100221A1/ru unknown
- 1999-08-06 KR KR1020017001635A patent/KR20010072323A/ko not_active Withdrawn
-
2001
- 2001-02-06 NO NO20010629A patent/NO20010629L/no not_active Application Discontinuation
- 2001-03-06 BG BG105310A patent/BG105310A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1321155A (zh) | 2001-11-07 |
| TR200100444T2 (tr) | 2001-07-23 |
| PT1100796E (pt) | 2003-09-30 |
| DE69907467T2 (de) | 2004-03-11 |
| KR20010072323A (ko) | 2001-07-31 |
| ID27914A (id) | 2001-05-03 |
| NO20010629L (no) | 2001-03-20 |
| EP1100796A1 (de) | 2001-05-23 |
| HK1038230A1 (en) | 2002-03-08 |
| CA2339857A1 (en) | 2000-02-17 |
| EA200100221A1 (ru) | 2001-08-27 |
| EP1321465A2 (de) | 2003-06-25 |
| PL345885A1 (en) | 2002-01-14 |
| ES2198940T3 (es) | 2004-02-01 |
| AP0102072A0 (en) | 2001-02-06 |
| SK1972001A3 (en) | 2001-08-06 |
| HUP0105466A3 (en) | 2002-11-28 |
| EP1321465A3 (de) | 2003-09-03 |
| NO20010629D0 (no) | 2001-02-06 |
| HUP0105466A2 (hu) | 2002-05-29 |
| IL141286A0 (en) | 2002-03-10 |
| BG105310A (en) | 2001-12-29 |
| EP1100796B1 (de) | 2003-05-02 |
| DE69907467D1 (de) | 2003-06-05 |
| AU5428999A (en) | 2000-02-28 |
| JP2002522434A (ja) | 2002-07-23 |
| BR9912858A (pt) | 2001-11-20 |
| AP2001002072A0 (en) | 2001-03-31 |
| DK1100796T3 (da) | 2003-08-25 |
| WO2000008017A1 (en) | 2000-02-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69631298D1 (de) | Verfahren zur Herstellung von Paroxetinhydrochloridanhydrat | |
| DE60008136D1 (de) | Verbessertes verfahren zur herstellung von n-substituierte aminotetraline | |
| DE60030949D1 (de) | Verfahren zur herstellung einer karte | |
| DE60125755D1 (de) | Verfahren zur herstellung einer flexodruckplatte | |
| ATE247627T1 (de) | Verfahren zur herstellung nicht-hygroscopische l (-) - carnitine salze | |
| DE69906491D1 (de) | VERFAHREN ZUR HERSTELLUNG EINER SiCOI-STRUKTUR | |
| DE69841475D1 (de) | Verfahren zur Herstellung eines MOSFET | |
| DE69840399D1 (de) | Verfahren zur Herstellung einer Gate-Elektrode | |
| DE69911404D1 (de) | Verfahren zur herstellen einer hülse | |
| DE69919412D1 (de) | Verfahren zur herstellung von polyolefine | |
| ATE249417T1 (de) | Verfahren zur herstellung von l- phenylephrinhydrochlorid | |
| DE69840320D1 (de) | Verfahren zur Herstellung einer Gateelektrode | |
| ATE221050T1 (de) | Verfahren zur herstellung von lercanidipin hydrochlorid | |
| ATE297379T1 (de) | Verfahren zur herstellung eines geschützten 4- aminomethyl-pyrrolidin-3-ons | |
| DE50009805D1 (de) | Verfahren zur herstellung einer torsionsfeder | |
| ATE291356T1 (de) | Verfahren zur herstellung einer aromazusammensetzung auf pilzbasis | |
| DE69919408D1 (de) | Verfahren zur herstellung von polyolefine | |
| DE60003264D1 (de) | Verfahren zur herstellung von glycerylethern | |
| ATE316518T1 (de) | Verfahren zur herstellung von (r)-2-alkyl-3- phenyl-1-propanolen | |
| DE69616543D1 (de) | Verfahren zur herstellung von ropivacainehydrochlorid-monohydrat | |
| ATE234269T1 (de) | Verfahren zur herstellung von cis-1-2-(4-(6- | |
| ATE239016T1 (de) | Verfahren zur herstellung von einer nicht- kristallinen wasswerfreien form von paroxetin hydrochlorid | |
| DE60128544D1 (de) | Verfahren zur herstellung einer siliziumschmelze | |
| DE60114214D1 (de) | Verfahren zur herstellung einer zahnbürste | |
| DE50113402D1 (de) | Verfahren zur Herstellung einer Hochspannungsdurchführung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1100796 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |