BR9912858A - Processo para preparação de uma forma deanidrato não cristalino de cloridrato deparoxetina - Google Patents

Processo para preparação de uma forma deanidrato não cristalino de cloridrato deparoxetina

Info

Publication number
BR9912858A
BR9912858A BR9912858-6A BR9912858A BR9912858A BR 9912858 A BR9912858 A BR 9912858A BR 9912858 A BR9912858 A BR 9912858A BR 9912858 A BR9912858 A BR 9912858A
Authority
BR
Brazil
Prior art keywords
deparoxetine
crystalline
preparing
hydrochloride form
propan
Prior art date
Application number
BR9912858-6A
Other languages
English (en)
Inventor
Victor Witold Jacewicz
Neal Ward
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9817196.0A external-priority patent/GB9817196D0/en
Priority claimed from GBGB9828777.4A external-priority patent/GB9828777D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of BR9912858A publication Critical patent/BR9912858A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"PROCESSO PARA PREPARAçãO DE, UMA FORMA DEANIDRATO NãO CRISTALINO DE CLORIDRATO DEPAROXETINA". Solvato de propan-2-ol de cloridrato de paroxetinaé dessolvatado para remover propan-2-ol e preparar anidrato decloridrato de paroxetina por aquecimento da massa de solvato eaumentar a temperatura do aquecimento conforme a quantidadede propan-2-ol remanescente na massa de solvato diminui.
BR9912858-6A 1998-08-07 1999-08-06 Processo para preparação de uma forma deanidrato não cristalino de cloridrato deparoxetina BR9912858A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9817196.0A GB9817196D0 (en) 1998-08-07 1998-08-07 Novel process
GBGB9828777.4A GB9828777D0 (en) 1998-12-29 1998-12-29 Novel compounds
PCT/GB1999/002592 WO2000008017A1 (en) 1998-08-07 1999-08-06 Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride

Publications (1)

Publication Number Publication Date
BR9912858A true BR9912858A (pt) 2001-11-20

Family

ID=26314179

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9912858-6A BR9912858A (pt) 1998-08-07 1999-08-06 Processo para preparação de uma forma deanidrato não cristalino de cloridrato deparoxetina

Country Status (24)

Country Link
EP (2) EP1100796B1 (pt)
JP (1) JP2002522434A (pt)
KR (1) KR20010072323A (pt)
CN (1) CN1321155A (pt)
AP (2) AP2001002072A0 (pt)
AT (1) ATE239016T1 (pt)
AU (1) AU5428999A (pt)
BG (1) BG105310A (pt)
BR (1) BR9912858A (pt)
CA (1) CA2339857A1 (pt)
DE (1) DE69907467T2 (pt)
DK (1) DK1100796T3 (pt)
EA (1) EA200100221A1 (pt)
ES (1) ES2198940T3 (pt)
HK (1) HK1038230A1 (pt)
HU (1) HUP0105466A3 (pt)
ID (1) ID27914A (pt)
IL (1) IL141286A0 (pt)
NO (1) NO20010629L (pt)
PL (1) PL345885A1 (pt)
PT (1) PT1100796E (pt)
SK (1) SK1972001A3 (pt)
TR (1) TR200100444T2 (pt)
WO (1) WO2000008017A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1394160A1 (en) * 1996-06-13 2004-03-03 SUMIKA FINE CHEMICALS Co., Ltd. Process for preparing crystalline paroxetin hydrochloride
JP3796351B2 (ja) 1998-04-13 2006-07-12 住友化学株式会社 パロキセチン塩酸塩無水和物の乾燥方法
GB9923446D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
AU2002224322A1 (en) * 2000-11-17 2002-05-27 Eli Lilly And Company Lactam dipeptide and its use in inhibiting beta-amyloid peptiderelease
EP1552833B1 (en) * 2002-10-16 2016-12-28 Takeda Pharmaceutical Company Limited Process for producing an amorphous optically active isomer of lansoprazole

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
EP0223403B1 (en) * 1985-10-25 1993-08-04 Beecham Group Plc Piperidine derivative, its preparation, and its use as medicament
SK283608B6 (sk) * 1995-02-06 2003-10-07 Smithkline Beecham Plc Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie
AP9901604A0 (en) * 1997-01-15 1999-09-30 Smithkline Beecham Plc Paroxetine compositions.
JP3796351B2 (ja) * 1998-04-13 2006-07-12 住友化学株式会社 パロキセチン塩酸塩無水和物の乾燥方法

Also Published As

Publication number Publication date
WO2000008017A1 (en) 2000-02-17
JP2002522434A (ja) 2002-07-23
TR200100444T2 (tr) 2001-07-23
EP1100796B1 (en) 2003-05-02
PL345885A1 (en) 2002-01-14
EP1321465A3 (en) 2003-09-03
NO20010629D0 (no) 2001-02-06
EA200100221A1 (ru) 2001-08-27
EP1321465A2 (en) 2003-06-25
ATE239016T1 (de) 2003-05-15
AP0102072A0 (en) 2001-02-06
CN1321155A (zh) 2001-11-07
SK1972001A3 (en) 2001-08-06
PT1100796E (pt) 2003-09-30
HK1038230A1 (en) 2002-03-08
DK1100796T3 (da) 2003-08-25
HUP0105466A2 (hu) 2002-05-29
EP1100796A1 (en) 2001-05-23
AP2001002072A0 (en) 2001-03-31
DE69907467T2 (de) 2004-03-11
AU5428999A (en) 2000-02-28
KR20010072323A (ko) 2001-07-31
BG105310A (en) 2001-12-29
IL141286A0 (en) 2002-03-10
DE69907467D1 (de) 2003-06-05
HUP0105466A3 (en) 2002-11-28
ES2198940T3 (es) 2004-02-01
CA2339857A1 (en) 2000-02-17
ID27914A (id) 2001-05-03
NO20010629L (no) 2001-03-20

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]