ATE228564T1 - Zusammensetzung aus mehreren immunreaktiven hepatitis-c-virus-polypeptiden - Google Patents
Zusammensetzung aus mehreren immunreaktiven hepatitis-c-virus-polypeptidenInfo
- Publication number
- ATE228564T1 ATE228564T1 AT92919917T AT92919917T ATE228564T1 AT E228564 T1 ATE228564 T1 AT E228564T1 AT 92919917 T AT92919917 T AT 92919917T AT 92919917 T AT92919917 T AT 92919917T AT E228564 T1 ATE228564 T1 AT E228564T1
- Authority
- AT
- Austria
- Prior art keywords
- hepatitis
- composition
- virus polypeptides
- multiple immunoreactive
- immunoreactive
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 241000711549 Hepacivirus C Species 0.000 title 1
- 208000010710 hepatitis C virus infection Diseases 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/82—Hepatitis associated antigens and antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/826—Viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75957591A | 1991-09-13 | 1991-09-13 | |
| PCT/US1992/007683 WO1993006126A1 (en) | 1991-09-13 | 1992-09-11 | Immunoreactive hepatitis c virus polypeptide compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE228564T1 true ATE228564T1 (de) | 2002-12-15 |
Family
ID=25056174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92919917T ATE228564T1 (de) | 1991-09-13 | 1992-09-11 | Zusammensetzung aus mehreren immunreaktiven hepatitis-c-virus-polypeptiden |
Country Status (16)
| Country | Link |
|---|---|
| US (6) | US5756312A (de) |
| EP (1) | EP0608261B1 (de) |
| JP (5) | JPH06511149A (de) |
| AT (1) | ATE228564T1 (de) |
| AU (1) | AU679429B2 (de) |
| BG (1) | BG62973B1 (de) |
| CA (1) | CA2116764C (de) |
| DE (1) | DE69232859T2 (de) |
| DK (1) | DK0608261T3 (de) |
| ES (1) | ES2182822T3 (de) |
| FI (1) | FI112438B (de) |
| HU (1) | HU227510B1 (de) |
| PL (2) | PL171489B1 (de) |
| RO (1) | RO116199B1 (de) |
| RU (2) | RU2136311C1 (de) |
| WO (1) | WO1993006126A1 (de) |
Families Citing this family (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6596476B1 (en) * | 1989-12-22 | 2003-07-22 | Abbott Laboratories | Hepatitis C assay |
| DE69232859T2 (de) * | 1991-09-13 | 2003-04-10 | Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville | Zusammensetzung aus mehreren immunreaktiven hepatitis-c-virus-polypeptiden |
| US6297048B1 (en) * | 1992-02-04 | 2001-10-02 | Chiron Corporation | Hepatitis therapeutics |
| US6709828B1 (en) | 1992-03-06 | 2004-03-23 | N.V. Innogenetics S.A. | Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them |
| US6667387B1 (en) | 1996-09-30 | 2003-12-23 | N.V. Innogenetics S.A. | HCV core peptides |
| DE69332485T2 (de) * | 1992-08-11 | 2003-11-13 | The President And Fellows Of Harvard College, Cambridge | Immunmodulierende peptide |
| US7255997B1 (en) | 1993-04-27 | 2007-08-14 | N.V. Innogenetics S.A. | Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents |
| SG50563A1 (en) | 1993-04-27 | 1998-07-20 | Innogenetics Nv | New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents |
| WO1994026306A1 (en) | 1993-05-12 | 1994-11-24 | Chiron Corporation | Conserved motif of hepatitis c virus e2/ns1 region |
| US5514539A (en) * | 1993-06-29 | 1996-05-07 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines |
| ES2239819T3 (es) * | 1993-11-04 | 2005-10-01 | Innogenetics N.V. | Epitopos inmunodominantes de celulas t humanas del virus de la hepatitis c. |
| AU688953B2 (en) | 1994-07-25 | 1998-03-19 | Boehringer Mannheim Gmbh | Determination of a specific immunoglobulin using multiple antigens |
| BR9506059A (pt) * | 1994-07-29 | 1997-10-28 | Innogenetics Nv | Proteinas envelopes purificadas de virus c para uso de diagnóstico e terapêutico |
| BR9509421A (pt) | 1994-10-21 | 1997-09-30 | Innogenetics Nv | Novas sequências de genotipos de vírus de hepatite C e uso como agentes profiláticos terapêuticos e diagnósticos |
| US6110465A (en) * | 1995-06-07 | 2000-08-29 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and deduced amino acid sequences of hypervariable region 1 of the envelope 2 gene of isolates of hepatitis C virus and the use of reagents derived from these hypervariable sequences in diagnostic methods and vaccines |
| US7235394B1 (en) | 1995-08-29 | 2007-06-26 | Washington University | Functional DNA clone for hepatitis C virus (HCV) and uses thereof |
| US6127116A (en) * | 1995-08-29 | 2000-10-03 | Washington University | Functional DNA clone for hepatitis C virus (HCV) and uses thereof |
| US7045363B2 (en) * | 1996-05-01 | 2006-05-16 | Fujirebio Inc. | Nucleic acid-bound polypeptide method of producing nucleic acid-bound polypeptide and immunoassay using the polypeptide |
| US6001613A (en) * | 1996-05-24 | 1999-12-14 | Board Of Regents Of University Of Nebraska | Plasmid bearing a cDNA copy of the genome of bovine viral diarrhea virus, chimeric derivatives thereof, and method of producing an infectious bovine viral diarrhea virus using said plasmid |
| CA2269097C (en) | 1996-11-08 | 2007-01-09 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Synthesis and purification of hepatitis c virus-like particles |
| EP0870830A3 (de) * | 1997-02-10 | 2004-02-25 | Advanced Life Science Institute, Inc. | Chimäres Hepatitis C-Virusantigen |
| US7049428B1 (en) * | 1998-03-04 | 2006-05-23 | Washington University | HCV variants |
| US7338759B1 (en) | 1997-03-04 | 2008-03-04 | Washington University | HCV variants |
| DE69841919D1 (de) * | 1997-11-06 | 2010-11-11 | Innogenetics Nv | Multimere peptide, die auf dem hepatitis c virus hüllprotein basieren, für diagnostische verwendung und für impfzwecke |
| US7157435B2 (en) | 1998-04-15 | 2007-01-02 | The Regents Of The University Of California | Methods for modulation of the effects of aging on the primate brain |
| US6683058B1 (en) | 1998-04-15 | 2004-01-27 | Regents Of The University Of California | Methods for therapy of neurodegenerative disease of the brain |
| US6451306B1 (en) | 1998-04-15 | 2002-09-17 | The Regents Of The University Of California | Methods for therapy of neurodegenerative disease of the brain |
| US6815431B2 (en) | 1998-04-15 | 2004-11-09 | Regents Of The University Of California | Methods for therapy of neurodegenerative disease of the brain |
| US7052830B1 (en) * | 1998-06-09 | 2006-05-30 | Branch Andrea D | Hepatitis C virus peptides and uses thereof |
| US7108855B2 (en) * | 1998-06-24 | 2006-09-19 | Innogenetics N.V. | Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use |
| US6548634B1 (en) * | 1998-09-30 | 2003-04-15 | Chiron Corporation | Synthetic peptides having FGF receptor affinity |
| US7091324B2 (en) | 1998-11-05 | 2006-08-15 | Board Of Trustees Of Leland Stanford Junior University | Prevention and treatment of HCV infection employing antibodies directed against conformational epitopes |
| US20030180284A1 (en) * | 1998-11-05 | 2003-09-25 | Board Of Trustees Of Leland Stanford Junior University | Prevention and treatment of HCV infection employing antibodies directed against conformational and linear epitopes |
| AU2487300A (en) | 1998-12-31 | 2000-07-31 | Chiron Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| US7935805B1 (en) | 1998-12-31 | 2011-05-03 | Novartis Vaccines & Diagnostics, Inc | Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof |
| CA2358915C (en) | 1998-12-31 | 2010-06-01 | Chiron Corporation | Modified hiv env polypeptides |
| US6602705B1 (en) * | 1998-12-31 | 2003-08-05 | Chiron Corporation | Expression of HIV polypeptides and production of virus-like particles |
| US6740323B1 (en) | 1999-11-24 | 2004-05-25 | Chiron Corporation | HBV/HCV virus-like particle |
| EP1535628B1 (de) * | 1999-11-24 | 2013-07-31 | Novartis Vaccines and Diagnostics, Inc. | Hbv/hcv virus-ähnliche teilchen |
| EP1301199B1 (de) * | 2000-07-19 | 2017-07-12 | The Regents of The University of California | Verfahren zur behandlung neurodegenerativer krankheiten des gehirns |
| AU2001290178A1 (en) | 2000-08-17 | 2002-02-25 | Tripep Ab | A hepatitis c virus non-structural ns3/4a fusion gene |
| US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
| RU2286172C2 (ru) | 2000-08-17 | 2006-10-27 | Трипеп Аб | Вакцины, содержащие рибавирин, и способы их использования |
| US6680059B2 (en) | 2000-08-29 | 2004-01-20 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| EP1326625A4 (de) | 2000-09-13 | 2005-05-04 | Hawaii Biotech Inc | Immunogene zusammensetzung von hepatitis c und methoden für ihre verwendung |
| RU2195668C2 (ru) * | 2001-02-12 | 2002-12-27 | Мешандин Алексей Гаврилович | Способ постановки реакции агглютинационного иммунологического анализа |
| SK15762003A3 (sk) * | 2001-06-29 | 2005-01-03 | Chiron Corporation | Kompozícia vakcíny HCV E1E2 |
| EP1409694A4 (de) | 2001-07-05 | 2006-02-08 | Chiron Corp | Antigene typ-b- und/oder typ-c-hiv-polypeptide codierende polynukleotide, polypeptide und deren verwendungen |
| CA2634992C (en) | 2001-07-05 | 2012-10-16 | Novartis Vaccines And Diagnostics, Inc. | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| WO2003020876A2 (en) * | 2001-08-31 | 2003-03-13 | Chiron Corporation | Polynucleotides encoding antigenic hiv type b polypeptides, polypeptides and uses thereof |
| US20030170614A1 (en) * | 2001-08-31 | 2003-09-11 | Megede Jan Zur | Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof |
| AR045702A1 (es) * | 2001-10-03 | 2005-11-09 | Chiron Corp | Composiciones de adyuvantes. |
| BRPI0406694B8 (pt) * | 2003-01-10 | 2021-05-25 | Ablynx Nv | polipeptídios terapêutico, seus homólogos, seus fragmentos, que são usados nas modulações da agregação plaquetária |
| CA2525825A1 (en) | 2003-05-15 | 2005-01-27 | Chiron Corporation | Hiv polynucleotides and polypeptides derived from botswana mj4 |
| US20050202036A1 (en) * | 2003-07-22 | 2005-09-15 | Branch Andrea D. | Alternate reading frame polypeptides drived from hepatitis C and methods of their use |
| WO2005017125A2 (en) * | 2003-08-14 | 2005-02-24 | California Institute Of Molecular Medicine | Method for isolation and replication of infectious human hepatitis-c virus |
| US8124747B2 (en) | 2003-08-29 | 2012-02-28 | Innogenetics | HCV clade and prototype sequences thereof |
| CA2585672A1 (en) | 2004-11-01 | 2006-05-11 | Novartis Vaccines And Diagnostics Inc. | Combination approaches for generating immune responses |
| US7968697B2 (en) * | 2005-05-25 | 2011-06-28 | Chrontech Pharma Ab | Hepatitis C virus non-structural NS3/4A fusion gene |
| GB0524066D0 (en) * | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| WO2007084568A2 (en) | 2006-01-17 | 2007-07-26 | Health Research, Inc. | Heteroduplex tracking assay |
| US8071561B2 (en) * | 2007-08-16 | 2011-12-06 | Chrontech Pharma Ab | Immunogen platform |
| EP2201023A2 (de) * | 2007-09-14 | 2010-06-30 | GENimmune N.V. | Affinitäts-tag |
| SI2915564T1 (sl) | 2007-09-28 | 2021-03-31 | Alexion Pharmaceuticals, Inc. | Antidoti za zaviralce dejavnika Ksa in postopki njihove uporabe |
| WO2009130588A2 (en) * | 2008-04-22 | 2009-10-29 | Tripep Ab | Immunogen platform |
| US20100104555A1 (en) * | 2008-10-24 | 2010-04-29 | The Scripps Research Institute | HCV neutralizing epitopes |
| FI3604510T3 (fi) | 2009-03-30 | 2025-06-26 | Alexion Pharma Inc | Vastalääkkeitä tekijä xa:n estäjille ja menetelmiä niiden käyttämiseksi |
| US20100322943A1 (en) | 2009-06-17 | 2010-12-23 | Thomas Cantor | Therapeutic and diagnostic affinity purified specific polyclonal antibodies |
| PT2453910T (pt) | 2009-07-15 | 2016-12-07 | Portola Pharm Inc | Formulação de dose unitária de antídoto contra inibidores de fator xa para uso na prevenção de sangramento |
| CN103796639B (zh) | 2011-07-06 | 2017-05-31 | 诺华股份有限公司 | 阳离子水包油乳液 |
| RU2606846C2 (ru) | 2011-07-06 | 2017-01-10 | Новартис Аг | Эмульсии типа "масло в воде", которые содержат нуклеиновые кислоты |
| WO2013016449A2 (en) | 2011-07-26 | 2013-01-31 | Indicator Systems International, Inc. | Assays for the detection of microbes |
| FR2984328B1 (fr) | 2011-12-20 | 2016-12-30 | Bio-Rad Innovations | Procede de detection d'une infection par le virus de l'hepatite c |
| EP2825191B1 (de) | 2012-03-16 | 2019-08-28 | University Health Network | Lösliches toso protein und dessen verwendung zur behandlung von autoimmunerkrankungen |
| RU2520710C1 (ru) * | 2012-12-10 | 2014-06-27 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Челябинская государственная медицинская академия" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО ЧелГМА Минздравсоцразвития России) | Способ прогнозирования персистенции онкогенных типов вируса папилломы человека в цервикальном эпителии |
| US20150252434A1 (en) | 2014-03-07 | 2015-09-10 | University Health Network | Methods and compositions for detection of targets involved in cancer metastasis |
| RU2675108C2 (ru) * | 2015-06-15 | 2018-12-17 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт биомедицинской химии имени В.Н. Ореховича" (ИБМХ) | Композиция на основе синтетических пептидов и липидов для вакцины против гепатита с |
| US10287338B2 (en) | 2015-07-10 | 2019-05-14 | Miran NERSISSIAN | Factor VIII protein compositions and methods of treating of hemophilia A |
| EP3365027B1 (de) | 2015-10-14 | 2022-03-30 | Research Institute at Nationwide Children's Hospital | Hu-spezifische antikörper und deren verwendeng zur hemmung von biofilm |
| JP7514621B2 (ja) | 2017-01-04 | 2024-07-11 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | Dnabiiワクチンおよび強化された活性を有する抗体 |
| WO2018129092A1 (en) | 2017-01-04 | 2018-07-12 | Research Institute At Nationwide Children's Hospital | Antibody fragments for the treatment of biofilm-related disorders |
| CA3056088A1 (en) | 2017-03-15 | 2018-09-20 | Research Institute At Nationwide Children's Hospital | Composition and methods for disruption of bacterial biofilms without accompanying inflammation |
| AU2020311897A1 (en) | 2019-07-08 | 2022-02-03 | Research Institute At Nationwide Children's Hospital | Antibody compositions for disrupting biofilms |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3400079A1 (de) * | 1984-01-03 | 1985-07-11 | Röhm GmbH, 6100 Darmstadt | Wasserspreitendes kunststoffmaterial, verfahren zu seiner herstellung u. verwendung als verglasungs- und bedachungsmaterial |
| US4673634A (en) * | 1985-03-08 | 1987-06-16 | The United States Of America As Represented By The Department Of Health And Human Services | Purified antigen from non-A, non-B hepatitis causing factor |
| JPS6391328A (ja) * | 1986-10-07 | 1988-04-22 | Mitsubishi Kasei Corp | 非a非b型肝炎抗原 |
| NZ219516A (en) * | 1987-02-10 | 1991-02-26 | Wellcome Found | Fusion proteins of hbcag (hepatitis b virus core antigen) |
| CN1049686C (zh) * | 1987-11-18 | 2000-02-23 | 希龙股份有限公司 | 非a和非b肝炎病毒的诊断及疫苗 |
| US5350671A (en) * | 1987-11-18 | 1994-09-27 | Chiron Corporation | HCV immunoassays employing C domain antigens |
| US5191064A (en) * | 1988-09-30 | 1993-03-02 | The Research Foundation For Microbial Diseases (Osaka University) | Non-a, non-b hepatitis virus antigen peptide |
| JPH02167081A (ja) * | 1988-12-21 | 1990-06-27 | Tetsuo Nakamura | 非A非B型肝炎ウイルスゲノムRNA、cDNAおよびウイルス抗原蛋白質 |
| KR0185373B1 (ko) * | 1989-03-17 | 1999-05-01 | 로버트 피. 블랙버언 | Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용 |
| HUT59964A (en) * | 1989-05-18 | 1992-07-28 | Chiron Corp | Process for producing new nanbv diagnostica for determining hepatitis c virus |
| US5372928A (en) * | 1989-09-15 | 1994-12-13 | Chiron Corporation | Hepatitis C virus isolates |
| WO1991004262A1 (en) * | 1989-09-15 | 1991-04-04 | National Institute Of Health Of Japan | New hcv isolates |
| DE59109221D1 (de) * | 1990-11-03 | 2001-11-15 | Dade Behring Marburg Gmbh | HCV-spezifische Peptide, Mittel dazu und ihre Verwendung |
| DE69232859T2 (de) * | 1991-09-13 | 2003-04-10 | Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville | Zusammensetzung aus mehreren immunreaktiven hepatitis-c-virus-polypeptiden |
-
1992
- 1992-09-11 DE DE69232859T patent/DE69232859T2/de not_active Expired - Lifetime
- 1992-09-11 PL PL92302729A patent/PL171489B1/pl unknown
- 1992-09-11 CA CA002116764A patent/CA2116764C/en not_active Expired - Lifetime
- 1992-09-11 AU AU26436/92A patent/AU679429B2/en not_active Expired
- 1992-09-11 DK DK92919917T patent/DK0608261T3/da active
- 1992-09-11 JP JP5506119A patent/JPH06511149A/ja not_active Withdrawn
- 1992-09-11 ES ES92919917T patent/ES2182822T3/es not_active Expired - Lifetime
- 1992-09-11 RO RO94-00391A patent/RO116199B1/ro unknown
- 1992-09-11 WO PCT/US1992/007683 patent/WO1993006126A1/en not_active Ceased
- 1992-09-11 PL PL92313797A patent/PL171972B1/pl unknown
- 1992-09-11 AT AT92919917T patent/ATE228564T1/de active
- 1992-09-11 EP EP92919917A patent/EP0608261B1/de not_active Expired - Lifetime
- 1992-09-11 HU HU9400741A patent/HU227510B1/hu unknown
- 1992-09-11 RU RU94024561A patent/RU2136311C1/ru active
- 1992-09-11 RU RU98117084/14A patent/RU2212899C2/ru active
-
1994
- 1994-03-11 BG BG98653A patent/BG62973B1/bg unknown
- 1994-03-14 FI FI941199A patent/FI112438B/fi not_active IP Right Cessation
- 1994-04-19 US US08/231,368 patent/US5756312A/en not_active Expired - Lifetime
-
1995
- 1995-05-12 US US08/440,542 patent/US5670153A/en not_active Expired - Lifetime
- 1995-05-12 US US08/440,103 patent/US5670152A/en not_active Expired - Lifetime
- 1995-05-12 US US08/440,210 patent/US5766845A/en not_active Expired - Lifetime
- 1995-06-06 US US08/471,498 patent/US5728520A/en not_active Expired - Lifetime
-
1998
- 1998-03-24 US US09/046,604 patent/US6303292B1/en not_active Expired - Fee Related
-
2001
- 2001-07-11 JP JP2001211447A patent/JP2002167336A/ja not_active Withdrawn
-
2003
- 2003-09-18 JP JP2003326811A patent/JP2004073207A/ja not_active Withdrawn
-
2005
- 2005-01-27 JP JP2005020454A patent/JP4353905B2/ja not_active Expired - Lifetime
-
2008
- 2008-02-20 JP JP2008038799A patent/JP2008133301A/ja not_active Withdrawn
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE228564T1 (de) | Zusammensetzung aus mehreren immunreaktiven hepatitis-c-virus-polypeptiden | |
| FI935808A0 (fi) | Hepatit-C-virus (HCV) polypeptider | |
| RU94024561A (ru) | Иммунореактивные композиции, способ получения композиции, способы получения и обнаружения антител, набор днк, клетка-хозяин, способ получения белка | |
| EE200100292A (et) | Peptiidligandidega kinnituvate mitmeste immunogeensete komponentidega HBV tuuma antigeensed osakesed | |
| FI932561A0 (fi) | Proteiner med foeraendrade epitoper och foerfaranden foer deras framstaellning | |
| ATA117890A (de) | Komplexes virales antigen von hiv-1 bindendes rekombinantes protein | |
| AU8223187A (en) | T cell epitopes of the hepatitis b virus nucleocapsid protein | |
| DE69433971D1 (de) | Von menschlichen T-Zellen immunodominante Epitopen des Virus der C-Hepatitis | |
| ATA257190A (de) | Virales polypeptid | |
| CA2103887A1 (en) | Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof | |
| ATE173275T1 (de) | Von einem retrovirus aus der hiv-gruppe abgeleitete peptide und deren verwendung | |
| IL101425A0 (en) | Peptides and mixtures thereof for detecting antibodies to hepatitis c virus,methods for their use and pharmaceutical compositions containing the same | |
| DK0754704T3 (da) | Syntetiske antigener til påvisning af antistoffer mod hepatitis c-virus | |
| IL128826A0 (en) | A crystallizable composition comprising a hepatitis C virus NS3 like polypeptide complexed with a NS4 a-like peptide | |
| DE69232906D1 (de) | Detektion des Hepatis-C Virus. | |
| ES8500997A1 (es) | Un metodo para producir un peptido. | |
| IT1167607B (it) | Polipeptide avente attivita' di interferon, composizione che lo contiene e procedimento di preparazione | |
| FI812859A7 (fi) | Uudet karboksialkyyli-peptidit ja peptidien tioeetterit ja eetterit verenpainetta alentavina aineina. | |
| IT1170302B (it) | Polipeptide avente attivita' di interferon, composizione che lo contiene e procedimento di preparazione | |
| DE69928064D1 (de) | Mimotopen der hypervariabele region des e2 glykoproteins von hcv und deren verwendungen | |
| AU2370592A (en) | Epitopes of the env protein of the hepatitis c virus | |
| DE3751834D1 (de) | Selbstantigen der primären lebercirrhose | |
| FR2676068B1 (fr) | Souches recombinantes immunogenes de b. anthracis - compositions immunogenes les contenant. | |
| DK196689D0 (da) | Ekspression af praes2-proteinet for hepatitis b i methylotrophe gaerarter | |
| RU93043621A (ru) | Способы получения гликопротеинов нсv, способ очистки, аналитический набор, способ выявления нсv, способ элиминации нсv, способ индукции иммунитета, гликопротеины, иммунореагенты |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0608261 Country of ref document: EP |