ATE231557T1 - Detektion des hepatis-c virus. - Google Patents
Detektion des hepatis-c virus.Info
- Publication number
- ATE231557T1 ATE231557T1 AT92924761T AT92924761T ATE231557T1 AT E231557 T1 ATE231557 T1 AT E231557T1 AT 92924761 T AT92924761 T AT 92924761T AT 92924761 T AT92924761 T AT 92924761T AT E231557 T1 ATE231557 T1 AT E231557T1
- Authority
- AT
- Austria
- Prior art keywords
- hcv
- virus
- hepatis
- detection
- identified
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 241000711549 Hepacivirus C Species 0.000 abstract 5
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000003205 genotyping method Methods 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
- C07K16/109—Hepatitis C virus; Hepatitis G virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
- C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/18—Togaviridae; Flaviviridae
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/18—Togaviridae; Flaviviridae
- G01N2333/183—Flaviviridae, e.g. pestivirus, mucosal disease virus, bovine viral diarrhoea virus, classical swine fever virus (hog cholera virus) or border disease virus
- G01N2333/186—Hepatitis C; Hepatitis NANB
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/82—Hepatitis associated antigens and antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919124696A GB9124696D0 (en) | 1991-11-21 | 1991-11-21 | Hepatitis c virus |
GB929213362A GB9213362D0 (en) | 1992-06-24 | 1992-06-24 | Hcv-3 virus |
PCT/GB1992/002143 WO1993010239A2 (en) | 1991-11-21 | 1992-11-20 | Hepatitis-c virus testing |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE231557T1 true ATE231557T1 (de) | 2003-02-15 |
Family
ID=26299894
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92924761T ATE231557T1 (de) | 1991-11-21 | 1992-11-20 | Detektion des hepatis-c virus. |
Country Status (10)
Country | Link |
---|---|
US (6) | US5763159A (de) |
EP (1) | EP0610436B9 (de) |
JP (1) | JP3688290B2 (de) |
AT (1) | ATE231557T1 (de) |
AU (1) | AU671967B2 (de) |
CA (1) | CA2123875C (de) |
DE (2) | DE69232906T2 (de) |
ES (1) | ES2065863T3 (de) |
FI (1) | FI113967B (de) |
WO (1) | WO1993010239A2 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6667387B1 (en) | 1996-09-30 | 2003-12-23 | N.V. Innogenetics S.A. | HCV core peptides |
US6709828B1 (en) | 1992-03-06 | 2004-03-23 | N.V. Innogenetics S.A. | Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them |
EP1878797B1 (de) * | 1992-07-16 | 2010-04-28 | Advanced Life Science Institute, Inc | Antigene Peptide zur Gruppierung des Hepatitis-C-Virus, Kit damit und Verfahren zur Gruppierung unter Verwendung dieses Kits |
US7255997B1 (en) | 1993-04-27 | 2007-08-14 | N.V. Innogenetics S.A. | Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents |
ATE373093T1 (de) | 1993-04-27 | 2007-09-15 | Innogenetics Nv | Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimitteln und diagnostika |
US6881821B2 (en) * | 1993-05-05 | 2005-04-19 | Common Services Agency | Hepatitis-C virus type 4, 5, and 6 |
GEP20012421B (en) | 1993-05-10 | 2001-04-25 | Chiron Corp | Method for Typing Hepatitis C Virus and Reagents for Use Therein |
EP0729973A4 (de) * | 1993-10-29 | 1998-12-30 | Srl Inc | Eine antigene peptidverbindung und ein immunoassay-verfahren |
WO1995030746A1 (en) * | 1994-05-10 | 1995-11-16 | The General Hospital Corporation | Antisense inhibition of hepatitis c virus |
US7129337B1 (en) | 1994-10-21 | 2006-10-31 | Innogenetics N.V. | Sequences of hepatitis C virus genotypes and their use as prophylactic, therapeutic and diagnostic agents |
JPH0967395A (ja) * | 1995-08-31 | 1997-03-11 | S R L:Kk | 抗原ペプチド化合物および免疫学的測定方法 |
JPH10104237A (ja) * | 1996-09-27 | 1998-04-24 | S R L:Kk | 免疫測定用担体及びそれを用いた免疫測定方法 |
US20030022155A1 (en) * | 1999-04-14 | 2003-01-30 | Agata Budkowska | Method for detecting hepatitis c virus with hybridomas |
AU1236801A (en) | 1999-10-27 | 2001-05-08 | Chiron Corporation | Activation of hcv-specific t cells |
AU7446501A (en) * | 2000-06-14 | 2001-12-24 | J.Mitra And Co. Ltd. | Diagnostic kit for invitro detection of hepatitis c |
US20030232055A1 (en) * | 2000-07-31 | 2003-12-18 | Ruslan Medzhitov | Innate immune system-directed vaccines |
US20030175287A1 (en) * | 2001-01-03 | 2003-09-18 | Yale University | Innate immune system-directed vaccines |
US7424409B2 (en) * | 2001-02-20 | 2008-09-09 | Context-Based 4 Casting (C-B4) Ltd. | Stochastic modeling of time distributed sequences |
US20030152942A1 (en) * | 2001-05-09 | 2003-08-14 | Lance Fors | Nucleic acid detection in pooled samples |
US7196183B2 (en) | 2001-08-31 | 2007-03-27 | Innogenetics N.V. | Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent |
GB0210535D0 (en) * | 2002-05-08 | 2002-06-19 | Novartis Ag | Organic compounds |
US8124747B2 (en) | 2003-08-29 | 2012-02-28 | Innogenetics | HCV clade and prototype sequences thereof |
RU2456617C2 (ru) * | 2010-05-19 | 2012-07-20 | Федеральное бюджетное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" (ФБУН ГНЦ ВБ "Вектор") | Панель сывороток, содержащих антитела к антигенам hcv разных субтипов |
BR112013017961A2 (pt) * | 2011-01-13 | 2017-07-25 | Ortho Clinical Diagnostics Inc | antígeno tripleto para treponema pallidum |
WO2013150450A1 (en) * | 2012-04-02 | 2013-10-10 | Universidade Do Porto | Hcv homolog fragments, cell-lines and applications thereof |
EP2959915A1 (de) | 2014-06-23 | 2015-12-30 | Institut Pasteur | Chimäres Dengue-Virus-Polyepitop aus Fragmenten nichtstruktureller Proteine und deren Verbindung in einer immunogenen Zusammensetzung gegen Dengue-Virus-Infektion |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1049686C (zh) * | 1987-11-18 | 2000-02-23 | 希龙股份有限公司 | 非a和非b肝炎病毒的诊断及疫苗 |
KR0185373B1 (ko) * | 1989-03-17 | 1999-05-01 | 로버트 피. 블랙버언 | Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용 |
DK0398748T3 (da) * | 1989-05-18 | 2002-03-18 | Chiron Corp | NANBV-diagnostika: polynukleotider anvendelige til screening for hepatitis C virus |
DK0414475T3 (da) * | 1989-08-25 | 1998-02-09 | Chiron Corp | Fremgangsmåder til dyrkning af HCV i B- eller T-lymfocyt-cellelinier |
US5372928A (en) * | 1989-09-15 | 1994-12-13 | Chiron Corporation | Hepatitis C virus isolates |
CA2032907C (en) * | 1989-12-22 | 2002-05-14 | Richard R. Lesniewski | Hepatitis c assay |
EP0435229A1 (de) * | 1989-12-27 | 1991-07-03 | Sanwa Kagaku Kenkyusho Co., Ltd. | DNS-Gen von einem Non-A Non-B Hepatitis-Virus, seine Klonierung und Verwendung |
US5747239A (en) * | 1990-02-16 | 1998-05-05 | United Biomedical, Inc. | Synthetic peptides specific for the detection of antibodies to HCV, diagnosis of HCV infection and preventions thereof as vaccines |
KR940000755B1 (ko) * | 1990-02-16 | 1994-01-29 | 유나이티드 바이오메디칼 인코오포레이티드 | Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드 |
UA41266C2 (uk) * | 1990-04-04 | 2001-09-17 | Чірон Корпорейшн | Комбінація послідовностей епітопів вірусу гепатиту с (hcv), спосіб виявлення антитіл до вірусу гепатиту с (hcv), набір для виконання аналізу при виявленні антитіл до антигену гепатиту с (hcv) |
EP0933426A1 (de) * | 1990-06-25 | 1999-08-04 | The Research Foundation for Microbial Diseases of Osaka University | Non-A, Non-B Hepatitis Virus genomisches DNS und Antigenpolypeptide |
EP0468657A3 (en) * | 1990-07-09 | 1992-02-05 | Tonen Corporation | Non-a non b hepatitis-specific antigen and its use in hepatitus diagnosis |
CA2047792C (en) * | 1990-07-26 | 2002-07-02 | Chang Y. Wang | Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines |
CA2089080C (en) * | 1990-08-10 | 2007-04-03 | Michael Houghton | Nanbv diagnostics: polynucleotides useful for screening for hepatitis c virus |
EP0484787B1 (de) * | 1990-11-03 | 2001-10-10 | Dade Behring Marburg GmbH | HCV-spezifische Peptide, Mittel dazu und ihre Verwendung |
ATE252154T1 (de) * | 1991-05-08 | 2003-11-15 | Chiron Corp | Genomische hcv-sequenzen für diagnostik und therapie |
EP0532167A3 (en) * | 1991-08-09 | 1993-03-31 | Immuno Japan Inc. | Non-a, non-b hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems |
US5428145A (en) * | 1991-08-09 | 1995-06-27 | Immuno Japan, Inc. | Non-A, non-B, hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems |
ATE373093T1 (de) * | 1993-04-27 | 2007-09-15 | Innogenetics Nv | Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimitteln und diagnostika |
GEP20012421B (en) * | 1993-05-10 | 2001-04-25 | Chiron Corp | Method for Typing Hepatitis C Virus and Reagents for Use Therein |
EP3128216B1 (de) * | 2015-08-07 | 2019-03-13 | Claverham Limited | Hydraulikventil |
-
1992
- 1992-11-20 JP JP50911093A patent/JP3688290B2/ja not_active Expired - Lifetime
- 1992-11-20 AU AU30887/92A patent/AU671967B2/en not_active Ceased
- 1992-11-20 DE DE69232906T patent/DE69232906T2/de not_active Expired - Lifetime
- 1992-11-20 DE DE0610436T patent/DE610436T1/de active Pending
- 1992-11-20 WO PCT/GB1992/002143 patent/WO1993010239A2/en active IP Right Grant
- 1992-11-20 US US08/244,116 patent/US5763159A/en not_active Expired - Lifetime
- 1992-11-20 CA CA002123875A patent/CA2123875C/en not_active Expired - Lifetime
- 1992-11-20 AT AT92924761T patent/ATE231557T1/de active
- 1992-11-20 EP EP92924761A patent/EP0610436B9/de not_active Expired - Lifetime
- 1992-11-20 ES ES92924761T patent/ES2065863T3/es not_active Expired - Lifetime
-
1994
- 1994-05-20 FI FI942369A patent/FI113967B/fi not_active IP Right Cessation
-
2003
- 2003-03-25 US US10/396,964 patent/US7179470B2/en not_active Expired - Fee Related
-
2007
- 2007-01-12 US US11/652,862 patent/US7709006B2/en not_active Expired - Fee Related
-
2010
- 2010-03-19 US US12/728,030 patent/US7976849B2/en not_active Expired - Fee Related
-
2011
- 2011-07-11 US US13/180,082 patent/US8318421B2/en not_active Expired - Fee Related
-
2012
- 2012-07-13 US US13/548,523 patent/US20130164733A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
FI942369A0 (fi) | 1994-05-20 |
JP3688290B2 (ja) | 2005-08-24 |
DE69232906D1 (de) | 2003-02-27 |
DE69232906T2 (de) | 2004-01-15 |
US7179470B2 (en) | 2007-02-20 |
ES2065863T3 (es) | 2003-09-01 |
EP0610436B9 (de) | 2003-03-26 |
US20130164733A1 (en) | 2013-06-27 |
EP0610436B1 (de) | 2003-01-22 |
AU3088792A (en) | 1993-06-15 |
US5763159A (en) | 1998-06-09 |
US7976849B2 (en) | 2011-07-12 |
US8318421B2 (en) | 2012-11-27 |
WO1993010239A2 (en) | 1993-05-27 |
ES2065863T1 (es) | 1995-03-01 |
US20100266624A1 (en) | 2010-10-21 |
US20030198946A1 (en) | 2003-10-23 |
FI113967B (fi) | 2004-07-15 |
AU671967B2 (en) | 1996-09-19 |
JPH07501442A (ja) | 1995-02-16 |
CA2123875C (en) | 2005-05-24 |
WO1993010239A3 (en) | 1993-07-22 |
DE610436T1 (de) | 1995-08-03 |
US20110287410A1 (en) | 2011-11-24 |
CA2123875A1 (en) | 1993-05-27 |
US7709006B2 (en) | 2010-05-04 |
EP0610436A1 (de) | 1994-08-17 |
US20070128221A1 (en) | 2007-06-07 |
FI942369A (fi) | 1994-07-19 |
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