BR112013017961A2 - antígeno tripleto para treponema pallidum - Google Patents
antígeno tripleto para treponema pallidumInfo
- Publication number
- BR112013017961A2 BR112013017961A2 BR112013017961A BR112013017961A BR112013017961A2 BR 112013017961 A2 BR112013017961 A2 BR 112013017961A2 BR 112013017961 A BR112013017961 A BR 112013017961A BR 112013017961 A BR112013017961 A BR 112013017961A BR 112013017961 A2 BR112013017961 A2 BR 112013017961A2
- Authority
- BR
- Brazil
- Prior art keywords
- treponema pallidum
- triplet antigen
- triplet
- antigen
- pallidum
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/571—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses for venereal disease, e.g. syphilis, gonorrhoea
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/20—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/26—Infectious diseases, e.g. generalised sepsis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161432570P | 2011-01-13 | 2011-01-13 | |
| PCT/US2012/021323 WO2012097304A2 (en) | 2011-01-13 | 2012-01-13 | Treponema pallidum triplet antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013017961A2 true BR112013017961A2 (pt) | 2017-07-25 |
Family
ID=46507695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013017961A BR112013017961A2 (pt) | 2011-01-13 | 2012-01-13 | antígeno tripleto para treponema pallidum |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US8691950B2 (pt) |
| EP (1) | EP2663642B1 (pt) |
| JP (1) | JP5911889B2 (pt) |
| CN (2) | CN108085330A (pt) |
| BR (1) | BR112013017961A2 (pt) |
| CA (1) | CA2824758C (pt) |
| RU (1) | RU2588656C2 (pt) |
| WO (1) | WO2012097304A2 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140186861A1 (en) * | 2011-07-11 | 2014-07-03 | Uvic Industry Partnerships Inc. | Soluble treponema pallidum protein tp0453, tp0453-tp0326 fusion protein, and use in syphilis diagnosis |
| CN107533060B (zh) | 2015-03-10 | 2019-11-05 | 生物辐射实验室股份有限公司 | 组合密螺旋体和非密螺旋体梅毒测试 |
| CN109868240B (zh) * | 2019-03-07 | 2020-11-27 | 北京新创生物工程有限公司 | 一种梅毒螺旋体p15-17-47突变体、编码基因、重组载体、重组工程菌及其应用与制备方法 |
| CN110305927B (zh) * | 2019-08-07 | 2023-03-28 | 郑州伊美诺生物技术有限公司 | 利用重组大肠杆菌发酵制备包被tp抗原的方法 |
| CN110981947B (zh) * | 2019-12-16 | 2021-10-08 | 四川安可瑞新材料技术有限公司 | 梅毒螺旋体tp47重组抗原的制备及应用 |
| CN115397465A (zh) * | 2020-04-24 | 2022-11-25 | 美国西门子医学诊断股份有限公司 | 用于针对抗体的免疫测定的校准和质量控制试剂 |
| EP4138915A4 (en) * | 2020-04-24 | 2024-04-24 | Siemens Healthcare Diagnostics, Inc. | COMPOSITIONS, KITS AND METHODS FOR ANTIMICROBIAL SEROLOGY TESTS USING ANTI-HUMAN IMMUNOGLOBULIN ANTIBODIES |
| CN111575308B (zh) * | 2020-05-25 | 2021-12-03 | 四川安可瑞新材料技术有限公司 | 梅毒螺旋体重组嵌合抗原及其制备方法、用途 |
| CN113004380B (zh) * | 2021-02-18 | 2022-06-28 | 青岛硕景生物科技有限公司 | 一种梅毒螺旋体重组抗原、制备及应用 |
| CN114163539A (zh) * | 2021-12-14 | 2022-03-11 | 青岛硕景生物科技有限公司 | Tp重组抗原及其制备方法和应用 |
| CN114703154B (zh) * | 2022-03-30 | 2024-01-09 | 云南大学 | 一种多肽、含有其的蛋白及应用 |
| CN118240037A (zh) * | 2022-12-23 | 2024-06-25 | 菲鹏生物股份有限公司 | 用于检测梅毒螺旋体抗体的重组抗原及其用途 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6472160B2 (en) * | 1919-09-08 | 2002-10-29 | Fujirebio Inc. | Immunoassay device and immunoassay method using the same |
| US4514498A (en) | 1982-05-26 | 1985-04-30 | The Board Of Regents, The University Of Texas System | Hybrid cell lines producing monoclonal antibodies directed against Treponema |
| US4740467A (en) | 1982-05-26 | 1988-04-26 | Board Of Regents, The University Of Texas | Methods for diagnosing syphilis |
| US5342921A (en) | 1985-03-28 | 1994-08-30 | Chiron Corporation | Superoxide dismutase fusion polypeptides for expression of mammalian proteins |
| US5350842A (en) * | 1986-09-30 | 1994-09-27 | Board Of Regents, The University Of Texas System | DNAs encoding Treponema pallidum antigens |
| US5681934A (en) | 1986-09-30 | 1997-10-28 | Board Of Regents, The University Of Texas System | 47-kilodalton antigen of Treponema pallidum |
| US4868118A (en) | 1986-09-30 | 1989-09-19 | Board Of Regents, The University Of Texas System | Cloning and expression of the 47-kilodalton antigen of treponema pallidum |
| KR930703613A (ko) | 1991-01-25 | 1993-11-30 | 챨스 엠. 브록 | 시료 희석물중 과산화물 디스뮤타제의 용도 |
| JP3688290B2 (ja) * | 1991-11-21 | 2005-08-24 | コモン サーヴィシス エージェンシー | Ｃ型肝炎ウイルス検査 |
| US5578456A (en) | 1994-02-28 | 1996-11-26 | Fujirebio Inc. | Anti-treponema pallidum antibody immunoassay |
| DE19536166C1 (de) | 1995-09-29 | 1997-03-06 | Siegfried Dr Krell | Verfahren zur Bestimmung von Antikörpern gegen Treponema pallidum (Syphilis) |
| JP3533857B2 (ja) * | 1995-12-25 | 2004-05-31 | 富士レビオ株式会社 | 梅毒トレポネマ融合抗原及び該融合抗原を用いた抗梅毒トレポネマ抗体の測定方法 |
| CA2193870C (en) | 1995-12-25 | 2000-07-18 | Nobuyuki Ise | Treponema pallidum fused antigen and assay for anti-treponema pallidum antibodies using the same fused antigen |
| JPH1090264A (ja) * | 1996-09-11 | 1998-04-10 | Sekisui Chem Co Ltd | 免疫学的診断試薬 |
| AU722630B2 (en) * | 1997-02-14 | 2000-08-10 | Higeta Shoyu Co., Ltd. | Modified Treponema pallidum-derived antigen protein |
| JPH10225294A (ja) * | 1997-02-14 | 1998-08-25 | Higeta Shoyu Co Ltd | 融合タンパク質、それをコードするｄｎａ、そのｄｎａを含む組換えベクター、その組換えベクターを含む形質転換体、融合タンパク質の製造法、抗トレポネーマ・パリダム抗体の測定法及び測定用試薬、梅毒感染診断薬並びに抗トレポネーマ・パリダム抗体の製造法 |
| BRPI0111731C1 (pt) * | 2000-06-15 | 2021-07-27 | Chiron Corp | suporte sólido de imunoensaio, métodos de detecção de infecção pelo vírus da hepatite c (hcv) em uma amostra biológica, e de produção de um suporte sólido de imunoensaio, e, kit de teste de imunodiagnóstico |
| CN1490411A (zh) * | 2002-10-19 | 2004-04-21 | 厦门市厦大建南抗性基因有限公司 | 一种从人体组织中获得人铜锌超氧化物歧化酶基因的方法 |
| WO2006138324A2 (en) * | 2005-06-14 | 2006-12-28 | Baylor College Of Medicine | Treponema pallidum antigens for vaccine development and diagnostic tests |
| US20090104650A1 (en) | 2007-09-14 | 2009-04-23 | Cryo-Cell International, Inc. | Infectious diseases testing of menstrual fluid, endometrial/menstrual cells, amniotic fluid, umbilical cord blood or other samples |
| CN101918834B (zh) * | 2008-01-07 | 2014-05-28 | 奥索临床诊断有限公司 | 用于同时分析能够彼此络合的蛋白质的校准物/对照物 |
| RU2397178C1 (ru) * | 2009-02-27 | 2010-08-20 | Федеральное государственное учреждение науки "Центральный научно-исследовательский институт эпидемиологии" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека | Диагностическая тест-система в формате иммуночипа и способ серологической дифференциальной диагностики сифилиса |
-
2012
- 2012-01-13 BR BR112013017961A patent/BR112013017961A2/pt not_active Application Discontinuation
- 2012-01-13 RU RU2013137760/10A patent/RU2588656C2/ru not_active IP Right Cessation
- 2012-01-13 US US13/350,235 patent/US8691950B2/en active Active
- 2012-01-13 CA CA2824758A patent/CA2824758C/en active Active
- 2012-01-13 JP JP2013549589A patent/JP5911889B2/ja active Active
- 2012-01-13 WO PCT/US2012/021323 patent/WO2012097304A2/en active Application Filing
- 2012-01-13 CN CN201711500503.5A patent/CN108085330A/zh active Pending
- 2012-01-13 EP EP12733941.4A patent/EP2663642B1/en active Active
- 2012-01-13 CN CN2012800052768A patent/CN103298941A/zh active Pending
-
2014
- 2014-02-28 US US14/193,530 patent/US9221884B2/en active Active
-
2015
- 2015-12-28 US US14/980,200 patent/US9902755B2/en active Active
-
2018
- 2018-01-09 US US15/865,594 patent/US10125177B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US8691950B2 (en) | 2014-04-08 |
| CN108085330A (zh) | 2018-05-29 |
| US20120237956A1 (en) | 2012-09-20 |
| RU2013137760A (ru) | 2015-02-20 |
| US20160115206A1 (en) | 2016-04-28 |
| CA2824758C (en) | 2019-06-04 |
| WO2012097304A3 (en) | 2012-09-13 |
| US9221884B2 (en) | 2015-12-29 |
| CA2824758A1 (en) | 2012-07-19 |
| WO2012097304A2 (en) | 2012-07-19 |
| US20180141980A1 (en) | 2018-05-24 |
| JP5911889B2 (ja) | 2016-04-27 |
| US9902755B2 (en) | 2018-02-27 |
| US10125177B2 (en) | 2018-11-13 |
| EP2663642B1 (en) | 2017-03-01 |
| JP2014506134A (ja) | 2014-03-13 |
| EP2663642A4 (en) | 2014-11-05 |
| US20140178907A1 (en) | 2014-06-26 |
| EP2663642A2 (en) | 2013-11-20 |
| RU2588656C2 (ru) | 2016-07-10 |
| CN103298941A (zh) | 2013-09-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |