FI932561A0 - Proteiner med foeraendrade epitoper och foerfaranden foer deras framstaellning - Google Patents

Proteiner med foeraendrade epitoper och foerfaranden foer deras framstaellning

Info

Publication number
FI932561A0
FI932561A0 FI932561A FI932561A FI932561A0 FI 932561 A0 FI932561 A0 FI 932561A0 FI 932561 A FI932561 A FI 932561A FI 932561 A FI932561 A FI 932561A FI 932561 A0 FI932561 A0 FI 932561A0
Authority
FI
Finland
Prior art keywords
protein
pharyngeal
intact epithelium
variants
epithelium
Prior art date
Application number
FI932561A
Other languages
English (en)
Other versions
FI932561A (fi
Inventor
Uffe Loevborg
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8205875&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI932561(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI932561A publication Critical patent/FI932561A/fi
Publication of FI932561A0 publication Critical patent/FI932561A0/fi

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38627—Preparations containing enzymes, e.g. protease or amylase containing lipase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38645—Preparations containing enzymes, e.g. protease or amylase containing cellulase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38654—Preparations containing enzymes, e.g. protease or amylase containing oxidase or reductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • General Engineering & Computer Science (AREA)
FI932561A 1990-12-05 1993-06-04 Proteiner med foeraendrade epitoper och foerfaranden foer deras framstaellning FI932561A0 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90610072 1990-12-05

Publications (2)

Publication Number Publication Date
FI932561A FI932561A (fi) 1993-06-04
FI932561A0 true FI932561A0 (fi) 1993-06-04

Family

ID=8205875

Family Applications (1)

Application Number Title Priority Date Filing Date
FI932561A FI932561A0 (fi) 1990-12-05 1993-06-04 Proteiner med foeraendrade epitoper och foerfaranden foer deras framstaellning

Country Status (11)

Country Link
EP (1) EP0561907B1 (fi)
JP (3) JP3355186B2 (fi)
KR (1) KR100237968B1 (fi)
AT (1) ATE170630T1 (fi)
AU (1) AU9052891A (fi)
BR (1) BR9107206A (fi)
CA (2) CA2095852C (fi)
DE (1) DE69130113T2 (fi)
DK (1) DK0561907T3 (fi)
FI (1) FI932561A0 (fi)
WO (1) WO1992010755A1 (fi)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL178045B1 (pl) * 1992-07-17 2000-02-29 Genencor Int Mutant proteazy do stosowania w detergentach, sekwencja DNA kodująca mutanta proteazy, sposób otrzymywania mutanta proteazy oraz kompozycja detergentowa
WO1996012186A1 (en) * 1994-10-14 1996-04-25 Chiron Mimotopes Pty. Ltd. Method and apparatus for efficient mimotope discovery
EP1017794A1 (en) 1997-02-06 2000-07-12 Novo Nordisk A/S Polypeptide-polymer conjugates having added and/or removed attachment groups
US6284246B1 (en) 1997-07-30 2001-09-04 The Procter & Gamble Co. Modified polypeptides with high activity and reduced allergenicity
CA2325568A1 (en) 1998-03-26 1999-09-30 The Procter & Gamble Company Serine protease variants having amino acid substitutions
US6908757B1 (en) 1998-03-26 2005-06-21 The Procter & Gamble Company Serine protease variants having amino acid deletions and substitutions
KR20010052223A (ko) * 1998-03-26 2001-06-25 데이비드 엠 모이어 아미노산 결실 및 치환을 갖는 세린 프로테아제 변이체
US6495136B1 (en) 1998-03-26 2002-12-17 The Procter & Gamble Company Proteases having modified amino acid sequences conjugated to addition moieties
US6642011B2 (en) * 1998-04-15 2003-11-04 Genencor International, Inc. Human protease and use of such protease for pharmaceutical applications and for reducing the allergenicity of non-human proteins
US6835550B1 (en) 1998-04-15 2004-12-28 Genencor International, Inc. Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
US6838269B1 (en) * 1998-04-15 2005-01-04 Genencor International, Inc. Proteins producing an altered immunogenic response and methods of making and using the same
US6936249B1 (en) 1998-04-15 2005-08-30 Genencor International, Inc. Proteins producing an altered immunogenic response and methods of making and using the same
US6461849B1 (en) * 1998-10-13 2002-10-08 Novozymes, A/S Modified polypeptide
US6686164B1 (en) 1998-10-30 2004-02-03 Novozymes A/S Low allergenic protein variants
DE69916306T2 (de) * 1998-10-30 2005-05-04 Novozymes A/S Niedrigallergene proteinvarianten
CA2342967A1 (en) * 1998-12-08 2000-06-15 Biovation Limited Modifying protein immunogenicity
EP1206526A2 (en) 1999-07-22 2002-05-22 The Procter & Gamble Company Subtilisin protease variants having amino acid deletions and substitutions in defined epitope regions
US6946128B1 (en) 1999-07-22 2005-09-20 The Procter & Gamble Company Protease conjugates having sterically protected epitope regions
MXPA02000840A (es) * 1999-07-22 2002-07-30 Procter & Gamble Variantes de proteasa de subtilisina que tienen substituciones de aminoacidos en regiones de epitopes definidas.
EP1196546A2 (en) * 1999-07-22 2002-04-17 The Procter & Gamble Company Intramolecularly cross-linked subtilisin proteases having reduced immunogenicity
CN1372593A (zh) * 1999-07-22 2002-10-02 宝洁公司 具有空间保护的表位区域的蛋白酶缀合物
KR20020021395A (ko) 1999-07-22 2002-03-20 데이비드 엠 모이어 입체적으로 보호된 ｃｌｉｐ 부위를 갖는 프로테아제콘쥬게이트
AU2001254623A1 (en) * 2000-04-28 2001-11-12 Novozymes A/S Production and use of protein variants having modified immunogenicity
PL366249A1 (en) 2000-07-28 2005-01-24 Henkel Kommanditgesellschaft Auf Aktien Novel amylolytic enzyme extracted from bacillus sp. a 7-7 (dsm 12368) and washing and cleaning agents containing this novel amylolytic enzyme
WO2002040997A2 (en) * 2000-10-02 2002-05-23 Genencor International, Inc. Production and use of proteins producing an altered immunogenic response
US6673580B2 (en) * 2000-10-27 2004-01-06 Genentech, Inc. Identification and modification of immunodominant epitopes in polypeptides
ZA200305980B (en) * 2001-02-12 2007-01-31 Res Dev Foundation Modified proteins, designer toxins, and methods of making thereof
EP1373296B1 (en) * 2001-03-23 2011-10-05 Genencor International, Inc. Proteins producing an altered immunogenic response and methods of making and using the same
WO2002079415A2 (en) 2001-03-30 2002-10-10 Lexigen Pharmaceuticals Corp. Reducing the immunogenicity of fusion proteins
JP2005501546A (ja) * 2001-09-04 2005-01-20 メルク　パテント　ゲゼルシャフト　ミット　ベシュレンクテル　ハフトング 修飾されたヒト成長ホルモン
JP2005514026A (ja) * 2001-12-31 2005-05-19 ジェネンコー・インターナショナル・インク 免疫反応の変化を生じるプロテアーゼ、ならびにその製造および利用方法
CA2472206C (en) * 2001-12-31 2013-04-09 Genencor International, Inc. Proteases producing an altered immunogenic response and methods of making and using the same
CN101177675B (zh) 2002-02-08 2014-05-21 诺维信公司 肌醇六磷酸酶变体
WO2003096869A2 (en) * 2002-05-16 2003-11-27 Alk Abelló A/S Recombinant bet. v. 1. allergen mutants, methods and process thereof
KR101211445B1 (ko) 2002-07-30 2012-12-12 다니스코 유에스 인크. 에어로졸 발생을 감소시킨 제형물
US20040121953A1 (en) * 2002-08-09 2004-06-24 Chirino Arthur J. Thrombopoiesis-stimulating proteins having reduced immunogenicity
ATE494368T1 (de) 2002-10-01 2011-01-15 Novozymes As Polypeptide der gh-61-familie
WO2004078960A1 (en) 2003-02-26 2004-09-16 Genencor International, Inc. Amylases producing an altered immunogenic response and methods of making and using the same
EP2500423B1 (en) 2003-02-26 2015-06-17 Danisco US Inc. Amylases producing an altered immunogenic response and methods of making and using the same
DK1639107T3 (da) 2003-06-19 2013-11-18 Novozymes As Forbedrede proteaser og fremgangsmåder til fremstilling deraf
CN1809634A (zh) 2003-06-19 2006-07-26 诺维信公司 蛋白酶
CA2539693A1 (en) 2003-10-10 2005-04-21 Novozymes A/S Protease variants
WO2005040220A1 (en) 2003-10-16 2005-05-06 Micromet Ag Multispecific deimmunized cd3-binders
WO2005066339A2 (en) 2004-01-06 2005-07-21 Novozymes A/S Polypeptides of alicyclobacillus sp.
AU2005206277B2 (en) 2004-01-22 2011-06-23 Merck Patent Gmbh Anti-cancer antibodies with reduced complement fixation
DE602005025202D1 (de) 2004-04-02 2011-01-20 Novozymes As Subtilasevarianten mit veränderter immunogenität
CN101014704A (zh) 2004-06-21 2007-08-08 诺维信公司 蛋白酶
WO2006037327A2 (en) 2004-10-04 2006-04-13 Novozymes A/S Polypeptides having phytase activity and polynucleotides encoding same
AR050895A1 (es) 2004-10-04 2006-11-29 Novozymes As Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican
US8119387B2 (en) 2005-08-16 2012-02-21 Novozymes A/S Polypeptides of strain Bacillus sp. P203
CA2625440C (en) 2005-10-11 2023-06-13 Micromet Ag Compositions comprising cross-species-specific antibodies and uses thereof
EP1960517A2 (en) 2005-12-06 2008-08-27 Genencor International, Inc. Perhydrolase epitopes
ZA200805400B (en) 2005-12-21 2009-09-30 Micromet Ag Pharmaceutical compositions with resistance to soluble CEA
PT1966245E (pt) 2005-12-30 2011-08-31 Merck Patent Gmbh Anticorpos anti-cd19 com imunogenicidade reduzida
ES2384055T3 (es) 2005-12-30 2012-06-28 Merck Patent Gmbh Variantes de la interleucina-12p40 con estabilidad mejorada
US7883711B2 (en) 2006-03-22 2011-02-08 Novozymes A/S Use of polypeptides having antimicrobial activity
BRPI0709732B1 (pt) 2006-04-04 2017-06-06 Novozymes As fitase, sequência de ácidos nucleicos isolada, construção de ácido nucleico, vetor de expressão recombinante, microrganismo recombinante, método para produzir a fitase, composição, método para melhorar o valor nutritivo de uma ração para animal, processo para reduzir os níveis de fitato no esterco de animal, método para o tratamento de proteínas de legume, e, uso da fitase ou da composição na ração para animal
BRPI0721103A2 (pt) 2006-12-21 2014-03-04 Novozymes As Lipase, método de determinação do desempenho da digestão in vitro de uma lipase em comparação com uma lipase de referência, uso de uma lipase ou de uma mistura de lipases, composição farmacêutica, e, método para o tratamento de doença
US8221743B2 (en) 2006-12-22 2012-07-17 Novozymes A/S Use of polypeptides against diseases caused by protozoans
CA2681392C (en) 2007-03-26 2017-08-01 Novozymes A/S Hafnia phytase
EP2933329B1 (en) 2008-09-26 2017-05-17 Novozymes A/S Hafnia phytase variants
JP5781501B2 (ja) 2009-04-22 2015-09-24 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 改変されたＦｃＲｎ結合部位を有する抗体融合タンパク質
JP5822841B2 (ja) 2009-11-05 2015-11-24 テバ・ファーマシューティカルズ・オーストラリア・ピーティワイ・リミテッド 変異型のｋｒａｓまたはｂｒａｆ遺伝子を含むがんの治療
WO2012119989A2 (en) 2011-03-04 2012-09-13 Oryzon Genomics, S.A. Methods and antibodies for the diagnosis and treatment of cancer
WO2016087514A1 (en) 2014-12-02 2016-06-09 Cemm - Forschungszentrum Für Molekulare Medizin Gmbh Anti-mutant calreticulin antibodies and their use in the diagnosis and therapy of myeloid malignancies
JP2023537982A (ja) 2020-08-13 2023-09-06 ノボザイムス アクティーゼルスカブ フィターゼ変異体及びそれをコードするポリヌクレオチド

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903068A (en) * 1972-12-26 1975-09-02 Us Health Education & Welfare Facile synthesis of human insulin by modification of porcine insulin
DK6488D0 (da) * 1988-01-07 1988-01-07 Novo Industri As Enzymer
DK316989D0 (da) * 1989-06-26 1989-06-26 Novo Nordisk As Enzymer

Also Published As

Publication number Publication date
CA2095852C (en) 2001-05-08
AU9052891A (en) 1992-07-08
WO1992010755A1 (en) 1992-06-25
KR930703610A (ko) 1993-11-30
CA2095852A1 (en) 1992-06-06
EP0561907B1 (en) 1998-09-02
ATE170630T1 (de) 1998-09-15
FI932561A (fi) 1993-06-04
DE69130113D1 (de) 1998-10-08
KR100237968B1 (ko) 2000-01-15
CA2331936C (en) 2007-07-31
JP2003174871A (ja) 2003-06-24
JP3355186B2 (ja) 2002-12-09
DE69130113T2 (de) 1999-05-12
JPH06502994A (ja) 1994-04-07
DK0561907T3 (da) 1999-05-31
EP0561907A1 (en) 1993-09-29
BR9107206A (pt) 1993-11-03
JP3450840B2 (ja) 2003-09-29
CA2331936A1 (en) 1992-06-06
JP2002101880A (ja) 2002-04-09

Similar Documents

Publication Publication Date Title
FI932561A0 (fi) Proteiner med foeraendrade epitoper och foerfaranden foer deras framstaellning
FI941199A0 (fi) Immunoreaktiiviset hepatiitti-C-viruksen polypeptidikoostumukset
DE69021002D1 (de) Schimärische Hepadnavirus-Kernantigenproteine.
BR9500732B8 (pt) Kit diagnóstico para a detecção de anticorpos contra vírus que causam imunodeficiência.
PT97159A (pt) Processo para a preparacao de uma proteina do antigenio de superficie da hepatite b ou de um seu fragmento e processo para a preparacao de uma vacina
ATE68826T1 (de) Verfahren zur herstellung von reifem, menschlichem serum-albumin.
ES2013328A6 (es) Un metodo para detectar anticuerpos contra antigenos hiv-1.
FI931393A (fi) Peptider foer anvaendning vid vaccinering och induktion av neutraliserande motkroppar mot humant immunbristvirus
BG97123A (bg) Производни на човешка, стимулирана от жлъчните соли, липаза и фармацевтични състави на тяхна основа
CA2178635A1 (en) Immunofluorescence assay for the detection of antibodies using recombinant antigens in insoluble form
FR2692282B1 (fr) Clonage du gene codant pour la proteine gp28.5 de t. gondii; fragments peptidiques issus de ladite proteine et leurs applications.
FI892222A0 (fi) Peptidalkoholer med antikoagulantverkan.
NO900758D0 (no) Fremgangsmaate for fremstilling av hybridprotein.
DK0471718T3 (da) Paracetamolholdigt farmaceutisk præparat
FR2624854B1 (fr) Nouveaux sulfonamides du benzylidene camphre derivant d'aminoacides et leur application en cosmetique, notamment en tant que filtres solaires
PT87857A (pt) Process for the preparation of novel immunossupressant peptides
DK13087D0 (da) Gensekvens til fremstilling af human serumalbumin i bacillus
NO881942L (no) Fremgangsmaate for fremstilling av fremmede proteiner i streptomyceten.
DE68925995D1 (de) Glasreinigerzusammensetzung
DE68922896D1 (de) RHOPTRY-MEMBRAN-ANTIGEN VON -i(PLASMODIUM FALCIPARUM).
ATE175357T1 (de) Empfängnisverhütender impfstoff
ITFI920071A0 (it) Antigeni ricombinanti proteici ad aumentata immunogenicita' contenenti il peptide rappresentato dalla sequenza vogeesndk
NO881779D0 (no) Fremstilling av l-fenylalanin med hjelp av rekombinante bakterier.
FR2363603A1 (fr) Compositions de polyterephtalate d'alkylene et d'ester sulfonique, cristallisant rapidement
IT8620596V0 (it) Lenti sovrapponibili per variare l'intensita' dell'assorbimento di luce degli occhiali.

Legal Events

Date Code Title Description
FC Application refused
FCK Appeal rejected

Free format text: APPLICATION REJECTED