ATE217859T1 - Verfahren zur herstellung von optisch aktiven mevalonolactonen - Google Patents

Verfahren zur herstellung von optisch aktiven mevalonolactonen

Info

Publication number
ATE217859T1
ATE217859T1 AT95909953T AT95909953T ATE217859T1 AT E217859 T1 ATE217859 T1 AT E217859T1 AT 95909953 T AT95909953 T AT 95909953T AT 95909953 T AT95909953 T AT 95909953T AT E217859 T1 ATE217859 T1 AT E217859T1
Authority
AT
Austria
Prior art keywords
fluid
flow
circuit
inlet port
outlet port
Prior art date
Application number
AT95909953T
Other languages
English (en)
Inventor
Hirokazu Ikeda
Tatsushi Murakami
Hiroo Matsumoto
Yoshio Ohara
Hiroyashu Kanda
Original Assignee
Daicel Chem
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daicel Chem, Nissan Chemical Ind Ltd filed Critical Daicel Chem
Application granted granted Critical
Publication of ATE217859T1 publication Critical patent/ATE217859T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3833—Chiral chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns recycling of the fraction to be distributed
    • B01D15/1821—Simulated moving beds
    • B01D15/185—Simulated moving beds characterized by the components to be separated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/262—Synthetic macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. obtained by polycondensation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Sustainable Development (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
AT95909953T 1994-02-25 1995-02-22 Verfahren zur herstellung von optisch aktiven mevalonolactonen ATE217859T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2859494 1994-02-25
PCT/JP1995/000251 WO1995023125A1 (fr) 1994-02-25 1995-02-22 Procede de production de compose de mevalonolactone optiquement actif

Publications (1)

Publication Number Publication Date
ATE217859T1 true ATE217859T1 (de) 2002-06-15

Family

ID=12252925

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95909953T ATE217859T1 (de) 1994-02-25 1995-02-22 Verfahren zur herstellung von optisch aktiven mevalonolactonen

Country Status (11)

Country Link
US (1) US5939552A (de)
EP (1) EP0747341B1 (de)
JP (1) JP3776452B2 (de)
KR (1) KR100355335B1 (de)
CN (1) CN1136183C (de)
AT (1) ATE217859T1 (de)
AU (1) AU691582B2 (de)
CA (1) CA2183071C (de)
DE (1) DE69526784T2 (de)
HU (1) HU214160B (de)
WO (1) WO1995023125A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107492A (en) * 1998-05-08 2000-08-22 Ucb, S.A. Process for the preparation of levetiracetam
EP1099694B1 (de) 1998-07-23 2005-08-17 Nissan Chemical Industries, Ltd. Verfahren zur herstellung von chinolinderivaten und zwischenprodukten davon
US7399409B2 (en) * 2000-10-13 2008-07-15 Daicel Chemical Industries, Ltd. Packing material for separation of optical isomer and method of separating optical isomer with the same
EP1334967A4 (de) * 2000-10-13 2008-05-07 Daicel Chem VERFAHREN ZUR HERSTELLUNG VON OPTISCH AKTIVEM (3R,5S,6E)-7-ç2-CYCLOPROPYL-4-(4-FLUORPHENYL)CHINOLIN-3-YL]-3,5-DIHYDROXY-6-HEPTENSÄUREETHYLESTER
FR2834227A1 (fr) * 2001-12-27 2003-07-04 Chiralsep Sarl Materiaux supports optiquement actifs, leur procede de preparation et leurs utilisations
US7339062B2 (en) 2002-09-20 2008-03-04 Nissan Chemical Industries, Ltd. Method for producing a 3,5-dihydroxy-6-heptenoate
CA2785954A1 (en) 2003-02-12 2004-08-26 Nissan Chemical Industries, Ltd. Crystalline forms of pitavastatin calcium
CN100400510C (zh) * 2003-04-24 2008-07-09 大赛璐化学工业株式会社 旋光性二羟基-庚烯酸酯的分离方法
DE602004027720D1 (de) * 2003-04-24 2010-07-29 Daicel Chem Mittel zur trennung optischer isomere
EP1637542A4 (de) * 2003-04-24 2007-04-04 Daicel Chem Trennmittel für optisches isomer
CN100391593C (zh) * 2003-04-24 2008-06-04 大赛璐化学工业株式会社 光学异构体用分离剂
EP1623978B1 (de) 2003-04-24 2010-08-11 Daicel Chemical Industries, Ltd. Verfahren zur herstellung von (3r,5s,6e)-7-[2-cyclopropyl-4-(4-fluorphenyl)chinolin-3-yl] -3,5-dihydroxy-6-heptensäureethylester
TWI343914B (en) * 2003-10-03 2011-06-21 Nissan Chemical Ind Ltd Process for producing high purity 3,5-dihydroxy-6-heptenoic acid derivative
JP2008507502A (ja) * 2004-07-23 2008-03-13 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 置換２−トリフルオロメチル−２ｈ−クロメン−３−カルボン酸誘導体を分離するためのエナンチオ選択的方法
US7627159B2 (en) * 2004-10-28 2009-12-01 Siemens Medical Solutions Usa, Inc. 2D visualization for rib analysis
JP2006150214A (ja) 2004-11-29 2006-06-15 Daicel Chem Ind Ltd 光学異性体用分離剤及び光学異性体用分離カラム
US8053543B2 (en) * 2006-05-09 2011-11-08 National University Corporation Nagoya University Filler for optical isomer separation
WO2007148834A1 (ja) 2006-06-23 2007-12-27 Daicel Chemical Industries, Ltd 光学異性体の分析方法又は分離方法
CN101259397B (zh) * 2007-12-21 2010-12-15 中国科学院山西煤炭化学研究所 一种模拟移动床反应器及其应用方法
JP5444226B2 (ja) 2008-08-26 2014-03-19 株式会社ダイセル 擬似移動床クロマトグラフィー分離装置を用いる目的物質の製造方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041507A (ja) * 1983-08-12 1985-03-05 Mitsubishi Kasei Techno Engineers Kk クロマト分離装置の制御方法
JPS60226829A (ja) * 1984-03-29 1985-11-12 Daicel Chem Ind Ltd 多糖誘導体より成る分離剤
JPH0718849B2 (ja) * 1986-03-12 1995-03-06 ダイセル化学工業株式会社 分離剤の製造方法
JPH03100459A (ja) * 1989-09-14 1991-04-25 Sumitomo Heavy Ind Ltd 擬似移動床式クロマト分離法
JP2925753B2 (ja) * 1990-02-23 1999-07-28 ダイセル化学工業株式会社 光学異性体の分離方法
JPH0695090B2 (ja) * 1990-09-21 1994-11-24 川崎重工業株式会社 擬似移動床式液体クロマト分離装置
JP3181349B2 (ja) * 1991-03-04 2001-07-03 ダイセル化学工業株式会社 多糖誘導体及びその製造法、並びに分離剤
JP3528186B2 (ja) * 1991-06-24 2004-05-17 日産化学工業株式会社 光学活性キノリンメバロン酸のジアステレオマー塩
JP3010816B2 (ja) * 1991-08-22 2000-02-21 ダイセル化学工業株式会社 光学分割における光学異性体と溶媒との回収方法、溶媒の循環使用方法、および光学異性体の再利用方法

Also Published As

Publication number Publication date
CA2183071C (en) 2001-12-18
HUT74486A (en) 1997-01-28
EP0747341B1 (de) 2002-05-22
AU1823195A (en) 1995-09-11
KR100355335B1 (ko) 2003-04-11
DE69526784D1 (de) 2002-06-27
DE69526784T2 (de) 2002-09-05
HU214160B (hu) 1998-01-28
US5939552A (en) 1999-08-17
CN1136183C (zh) 2004-01-28
KR970701165A (ko) 1997-03-17
AU691582B2 (en) 1998-05-21
CA2183071A1 (en) 1995-08-31
WO1995023125A1 (fr) 1995-08-31
EP0747341A1 (de) 1996-12-11
JP3776452B2 (ja) 2006-05-17
EP0747341A4 (de) 1998-09-30
CN1141028A (zh) 1997-01-22
HU9602291D0 (en) 1996-10-28

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UEP Publication of translation of european patent specification