DK2186A - Fremgangsmaade og apparat til chromatografisk separation af biologiske makromolekyler - Google Patents

Fremgangsmaade og apparat til chromatografisk separation af biologiske makromolekyler Download PDF

Info

Publication number
DK2186A
DK2186A DK2186A DK2186A DK2186A DK 2186 A DK2186 A DK 2186A DK 2186 A DK2186 A DK 2186A DK 2186 A DK2186 A DK 2186A DK 2186 A DK2186 A DK 2186A
Authority
DK
Denmark
Prior art keywords
solution
vmf
column
open sections
resin
Prior art date
Application number
DK2186A
Other languages
English (en)
Other versions
DK165391B (da
DK165391C (da
DK2186D0 (da
Inventor
Victor Sanchez
Beatrice Biscans
Jean-Pierre Couderc
Jean-Pierre Riba
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Publication of DK2186D0 publication Critical patent/DK2186D0/da
Publication of DK2186A publication Critical patent/DK2186A/da
Publication of DK165391B publication Critical patent/DK165391B/da
Application granted granted Critical
Publication of DK165391C publication Critical patent/DK165391C/da

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1807—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using counter-currents, e.g. fluidised beds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/146—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by ion-exchange
    • A23C9/1465—Chromatographic separation of protein or lactose fraction; Adsorption of protein or lactose fraction followed by elution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2215/00—Separating processes involving the treatment of liquids with adsorbents
    • B01D2215/02—Separating processes involving the treatment of liquids with adsorbents with moving adsorbents
    • B01D2215/021—Physically moving or fluidising the adsorbent beads or particles or slurry, excluding the movement of the entire columns

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Peptides Or Proteins (AREA)
DK002186A 1985-01-04 1986-01-03 Fremgangsmaade til chromatografisk separation af biologiske makromolekyler DK165391C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8500463 1985-01-04
FR8500463A FR2575666B1 (fr) 1985-01-04 1985-01-04 Procede et dispositif pour la separation chromatographique de macromolecules biologiques

Publications (4)

Publication Number Publication Date
DK2186D0 DK2186D0 (da) 1986-01-03
DK2186A true DK2186A (da) 1986-07-05
DK165391B DK165391B (da) 1992-11-23
DK165391C DK165391C (da) 1993-04-13

Family

ID=9315250

Family Applications (1)

Application Number Title Priority Date Filing Date
DK002186A DK165391C (da) 1985-01-04 1986-01-03 Fremgangsmaade til chromatografisk separation af biologiske makromolekyler

Country Status (12)

Country Link
US (1) US4976865A (da)
EP (1) EP0189611B1 (da)
AT (1) ATE42044T1 (da)
AU (1) AU577915B2 (da)
CA (1) CA1278529C (da)
DE (1) DE3569335D1 (da)
DK (1) DK165391C (da)
ES (1) ES8703288A1 (da)
FR (1) FR2575666B1 (da)
IE (1) IE58725B1 (da)
NO (1) NO166148C (da)
NZ (1) NZ214636A (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH674315A5 (da) * 1987-11-23 1990-05-31 Werner Hafner
FR2646993B1 (fr) * 1989-05-19 1993-08-13 Union Coop Agricole Frloyer alain frdupont patrick maschine zum handhaben zerbrechlicher produkte, wie kaesebruch bei der herstellung von kaese.
SE9101149D0 (sv) 1991-04-17 1991-04-17 Pharmacia Lkb Biotech Beads for down stream processing
FI97277C (fi) * 1993-01-25 1996-11-25 Suomen Sokeri Oy Kromatografinen erotuskolonni, sen sisärakenteet ja kromatografinen erotusmenetelmä
US6663780B2 (en) 1993-01-26 2003-12-16 Danisco Finland Oy Method for the fractionation of molasses
FI96225C (fi) 1993-01-26 1996-05-27 Cultor Oy Menetelmä melassin fraktioimiseksi
US6706188B2 (en) 1993-05-03 2004-03-16 Amersham Biociences Ab Process and means for down stream processing
US5795398A (en) 1994-09-30 1998-08-18 Cultor Ltd. Fractionation method of sucrose-containing solutions
US5902485A (en) * 1994-10-03 1999-05-11 Amersham Pharmacia Biotech Ab Access valve devices, their use in separation apparatus and corresponding methods
US6224776B1 (en) 1996-05-24 2001-05-01 Cultor Corporation Method for fractionating a solution
SE9700383D0 (sv) * 1997-02-04 1997-02-04 Pharmacia Biotech Ab An adsorption/separation method and a medium for adsorption/separation
US20020104801A1 (en) * 1998-04-06 2002-08-08 Nicolas Voute Small dense microporous solid support materials, their preparation,and use for purification of large macromolecules and bioparticles
FI107115B (fi) 1998-09-30 2001-06-15 Valio Oy Menetelmä naudan insuliinin poistamiseksi
EP1131146B1 (en) * 1998-10-31 2003-07-16 Amersham Biosciences AB A chromatographic process utilizing a fluidised bed
EP1175931A1 (en) * 2000-07-25 2002-01-30 Computer Cell Culture Center S.A. Integration of high cell density bioreactor operation with ultra fast on-line downstream processing
JP2004516896A (ja) * 2000-12-29 2004-06-10 アップフロント・クロマトグラフィー・アー／エス 細胞外体液からの特異的生体高分子物質の体外捕獲
EP1584242B1 (en) 2001-06-01 2010-01-20 Upfront Chromatography A/S Fractionation of protein containing mixtures
EP1480524B1 (en) 2002-03-07 2013-04-17 Upfront Chromatography A/S A process of isolating lactoferrin
US7094345B2 (en) * 2002-09-09 2006-08-22 Cytonome, Inc. Implementation of microfluidic components, including molecular fractionation devices, in a microfluidic system
CZ305371B6 (cs) * 2013-11-15 2015-08-19 Univerzita PalackĂ©ho Způsob separace syrovátkových proteinů z mléčného média a zařízení k provádění tohoto způsobu

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2959542A (en) * 1957-03-08 1960-11-08 Dow Chemical Co Continuous gas-lift ion-exchange process and apparatus
GB1070251A (en) * 1962-10-19 1967-06-01 Nat Res Dev Improvements in and relating to solid/fluid contacting
GB1148662A (en) * 1965-05-11 1969-04-16 Pretorius Victor Chromatographic process and apparatus therefor
DE1598049B2 (de) * 1965-06-03 1972-04-06 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und vorrichtung zur technischen durchfuehrung der saeulenchromatographie
GB1183833A (en) * 1966-08-11 1970-03-11 Victor Pretorious Improvements in Chromatographic Processes and Apparatus.
US3549526A (en) * 1968-01-31 1970-12-22 Hart Brown Contact process and apparatus
GB1422412A (en) * 1972-01-24 1976-01-28 Chiyoda Chem Eng Construct Co Method of and apparatus for the continuous treatment of water using activated-carbon
US3928193A (en) * 1975-02-14 1975-12-23 Suomen Sokeri Oy Process for large scale chromatography
FR2359634A2 (fr) * 1976-07-28 1978-02-24 Rhone Poulenc Ind Procede de separation de proteines par echange d'ions
FR2321932A1 (fr) * 1975-08-28 1977-03-25 Rhone Poulenc Ind Procede de separation de proteines par echange d'ions
US4100149A (en) * 1975-08-28 1978-07-11 Rhone-Poulenc Industries Method of separating proteins by ion exchange
US4284511A (en) * 1979-08-30 1981-08-18 General Technology Applications, Inc. Process for using magnetically ballasted sorbents
US4443231A (en) * 1982-02-02 1984-04-17 Exxon Research And Engineering Co. Continuous chromatographic separations in a magnetically stabilized fluidized bed
US4675113A (en) * 1984-11-28 1987-06-23 University Patents, Inc. Affinity chromatography using dried calcium alginate-magnetite separation media in a magnetically stabilized fluidized bed

Also Published As

Publication number Publication date
DE3569335D1 (en) 1989-05-18
NZ214636A (en) 1989-01-06
IE860012L (en) 1986-07-04
ATE42044T1 (de) 1989-04-15
CA1278529C (fr) 1991-01-02
AU5161285A (en) 1986-07-10
IE58725B1 (en) 1993-11-03
ES8703288A1 (es) 1987-03-01
DK165391B (da) 1992-11-23
DK165391C (da) 1993-04-13
NO166148C (no) 1991-06-05
FR2575666A1 (fr) 1986-07-11
EP0189611A1 (fr) 1986-08-06
ES550599A0 (es) 1987-03-01
NO855317L (no) 1986-07-07
AU577915B2 (en) 1988-10-06
EP0189611B1 (fr) 1989-04-12
FR2575666B1 (fr) 1989-08-18
US4976865A (en) 1990-12-11
DK2186D0 (da) 1986-01-03
NO166148B (no) 1991-02-25

Similar Documents

Publication Publication Date Title
DK2186A (da) Fremgangsmaade og apparat til chromatografisk separation af biologiske makromolekyler
SE8702755L (sv) Kromatografikolonn med horisontell stromning
TW351678B (en) Method for fractionating a solution to fractionate a solution
GB1508470A (en) Large scale chromatography
DE3580418D1 (de) Elektrophoretisches trennverfahren mit freier stroemung und apparat dafuer.
EP0323693B1 (en) Isomobility focusing in a magnetically stabilized fluidized bed
ATE228882T1 (de) Verwendung von kügelchen in einem wirbelbett
Burns et al. Application of magnetically stabilized fluidized beds to bioseparations
CA2183071A1 (en) A process for preparing optically active mevalonolactone compounds
FI97830B (fi) Menetelmä ja laite sellaisen aineen pitoisuuden määrittämiseksi, joka on sidottu virtaavan väliaineen hiukkasiin
DK565684A (da) Fremgangsmaade til koncentration af en suspension af mikroskopiske partikler, apparat til udoevelse af fremgangsmaaden samt dennes anvendelser
FI873588A (fi) Menetelmä huokoisten, kuorettomien, agglomeroitujen PVC-hartsihiukkasten valmistamiseksi
FR2575669B1 (fr) Procede pour la separation des isotopes d'uranium par chromatographie d'oxydoreduction
Seibert et al. Effect of hydrodynamic and magnetic stabilization on fluidized‐bed adsorption
DK0546127T3 (da) Biosyntetisk cerebrospinalvæskekontrol og fremgangsmåde til fremstilling deraf
IT1138580B (it) Processo per la separazione di isotopi con il metodo della distribuzione regolata utilizzando in particolare l'effetto di concentrazione isotopica
Evans et al. Countercurrent gradient chromatography: A continuous focusing technique
OA06840A (fr) Procédé de séparation sélective de l'uranium et du molydène contenus dans un solvant aminé.
Hisao Improved Apparatus for Countercurrent Chromatography Separations and Stable Methods for Monitoring the Effluent Thereof
Hwang et al. Studies on Goucoalkaloids in Plants I. High Performance Liquid Chromatographic Analysis of Glucoalkaloids in Periderm and Cortex of Potato (Solanum tuberosum var. May Queen)
Issaq High Performance Liquid Chromatography Separations Using Short Columns Packed with Spherical ODS Particles. II. Effect of Mobile Phase Composition on Resolution
HISAO Improved apparatus for countercurrent chromatography separations and stable methods for monitoring the effluent thereof(Patent Application)
Barth Polymer shear degradation during size exclusion chromatography
FR2568776B1 (fr) Isotopes anticancereux-decancerisants, procede et appareil pour leur synthese et leur conservation
DK507585D0 (da) Fremgangsmaade og apparat til tangential stroemningsseparation