ATE168678T1 - Heterozyklische derivate als plätchenaggregationsinhibitoren - Google Patents

Heterozyklische derivate als plätchenaggregationsinhibitoren

Info

Publication number
ATE168678T1
ATE168678T1 AT94910494T AT94910494T ATE168678T1 AT E168678 T1 ATE168678 T1 AT E168678T1 AT 94910494 T AT94910494 T AT 94910494T AT 94910494 T AT94910494 T AT 94910494T AT E168678 T1 ATE168678 T1 AT E168678T1
Authority
AT
Austria
Prior art keywords
aggregation inhibitors
heterocyclic derivatives
plate aggregation
plate
ylüphenoxybutyric
Prior art date
Application number
AT94910494T
Other languages
German (de)
English (en)
Inventor
Michael Garth Wayne
Michael James Smithers
John Wall Rayner
Alan Wellington Faull
Robert James Pearce
Andrew George Brewster
Richard Eden Shute
Stuart Dennett Mills
Peter William Rodney Caulkett
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939306453A external-priority patent/GB9306453D0/en
Priority claimed from GB939325605A external-priority patent/GB9325605D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Application granted granted Critical
Publication of ATE168678T1 publication Critical patent/ATE168678T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electroluminescent Light Sources (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT94910494T 1993-03-29 1994-03-28 Heterozyklische derivate als plätchenaggregationsinhibitoren ATE168678T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939306453A GB9306453D0 (en) 1993-03-29 1993-03-29 Heterocyclic derivatives
GB939325605A GB9325605D0 (en) 1993-12-15 1993-12-15 Heterocyclic derivatives

Publications (1)

Publication Number Publication Date
ATE168678T1 true ATE168678T1 (de) 1998-08-15

Family

ID=26302668

Family Applications (2)

Application Number Title Priority Date Filing Date
AT94910494T ATE168678T1 (de) 1993-03-29 1994-03-28 Heterozyklische derivate als plätchenaggregationsinhibitoren
AT97117909T ATE202345T1 (de) 1993-03-29 1994-03-28 Heterozyklische derivate als plätchenaggregationsinhibitoren

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT97117909T ATE202345T1 (de) 1993-03-29 1994-03-28 Heterozyklische derivate als plätchenaggregationsinhibitoren

Country Status (26)

Country Link
US (1) US5556977A (enExample)
EP (2) EP0825184B1 (enExample)
JP (1) JPH08508291A (enExample)
KR (1) KR100231089B1 (enExample)
CN (1) CN1120334A (enExample)
AT (2) ATE168678T1 (enExample)
AU (1) AU692438B2 (enExample)
BR (1) BR9406613A (enExample)
CA (1) CA2156070A1 (enExample)
CZ (1) CZ250995A3 (enExample)
DE (2) DE69411900T2 (enExample)
DK (2) DK0825184T3 (enExample)
ES (2) ES2119184T3 (enExample)
FI (1) FI954616L (enExample)
GB (1) GB9406143D0 (enExample)
GR (2) GR3027751T3 (enExample)
HU (2) HUT72088A (enExample)
IL (1) IL109144A (enExample)
NO (1) NO305244B1 (enExample)
NZ (1) NZ262941A (enExample)
PL (1) PL310889A1 (enExample)
PT (1) PT825184E (enExample)
SK (1) SK120895A3 (enExample)
TW (1) TW276254B (enExample)
WO (1) WO1994022834A1 (enExample)
ZW (1) ZW4294A1 (enExample)

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FR2734818B1 (fr) * 1995-06-01 1998-07-10 Zeneca Ltd Acide (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazine-1-yl- phenoxy}-butyrique, procede pour sa preparation et composition pharmaceutique le contenant
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US5854245A (en) * 1996-06-28 1998-12-29 Merck & Co., Inc. Fibrinogen receptor antagonists
WO1998000134A1 (en) * 1996-06-28 1998-01-08 Merck & Co., Inc. Fibrinogen receptor antagonists
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GB9715895D0 (en) 1997-07-29 1997-10-01 Zeneca Ltd Heterocyclic compounds
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JP2002516305A (ja) 1998-05-12 2002-06-04 アメリカン・ホーム・プロダクツ・コーポレイション インスリン抵抗性および高血糖症の治療に有用な２，３，５−置換ビフェニル
US6451827B2 (en) 1998-05-12 2002-09-17 Wyeth 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia
US6166069A (en) * 1998-05-12 2000-12-26 American Home Products Corporation Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
US6221902B1 (en) 1998-05-12 2001-04-24 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
US6699896B1 (en) 1998-05-12 2004-03-02 Wyeth Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
CA2338745A1 (en) * 1998-07-31 2000-02-10 Hamideh Zarrinmayeh Heterocyclyl sulphonamide derivatives
GB9902989D0 (en) 1999-02-11 1999-03-31 Zeneca Ltd Heterocyclic derivatives
AU4250200A (en) * 1999-04-19 2000-11-02 Coelacanth Corporation Ppar-(gamma) agonists as agents for the treatment of type ii diabetes
US6310081B1 (en) 1999-05-10 2001-10-30 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
ATE502928T1 (de) 2000-11-01 2011-04-15 Millennium Pharm Inc Stickstoffhaltige heterozyklische verbindungen und verfahren zu deren herstellung
DE202011000090U1 (de) 2011-01-14 2011-04-21 E-LEAD ELECTRONIC CO., LTD., Shengang Shiang Fahrzeug-Audiosystem mit auswechselbarem Plug-In-Computer
SG11202002032SA (en) 2017-09-22 2020-04-29 Jubilant Epipad LLC Heterocyclic compounds as pad inhibitors
CN111225915B (zh) 2017-10-18 2023-03-07 朱比兰特埃皮帕德有限公司 作为pad抑制剂的咪唑并吡啶化合物
AU2018362046B2 (en) 2017-11-06 2023-04-13 Jubilant Prodel LLC Pyrimidine derivatives as inhibitors of PD1/PD-L1 activation
AU2018372211B2 (en) 2017-11-24 2023-02-02 Jubilant Episcribe LLC, Heterocyclic compounds as PRMT5 inhibitors
CA3093527A1 (en) 2018-03-13 2019-09-19 Jubilant Prodel LLC Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation

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Also Published As

Publication number Publication date
ZW4294A1 (en) 1994-12-21
SK120895A3 (en) 1996-06-05
CZ250995A3 (en) 1996-01-17
CN1120334A (zh) 1996-04-10
DK0691959T3 (da) 1999-04-26
DE69427548D1 (de) 2001-07-26
HUT72088A (en) 1996-03-28
TW276254B (enExample) 1996-05-21
FI954616A7 (fi) 1995-09-28
AU6288994A (en) 1994-10-24
ES2159798T3 (es) 2001-10-16
ATE202345T1 (de) 2001-07-15
DE69411900T2 (de) 1998-12-10
KR100231089B1 (ko) 1999-11-15
PT825184E (pt) 2001-11-30
HU211336A9 (en) 1995-11-28
EP0691959B1 (en) 1998-07-22
GR3027751T3 (en) 1998-11-30
NZ262941A (en) 1997-07-27
NO953837L (no) 1995-09-28
CA2156070A1 (en) 1994-10-13
FI954616A0 (fi) 1995-09-28
EP0825184A1 (en) 1998-02-25
IL109144A0 (en) 1994-06-24
JPH08508291A (ja) 1996-09-03
HU9502290D0 (en) 1995-10-30
DE69427548T2 (de) 2002-04-18
US5556977A (en) 1996-09-17
WO1994022834A1 (en) 1994-10-13
AU692438B2 (en) 1998-06-11
GR3036640T3 (en) 2001-12-31
DE69411900D1 (de) 1998-08-27
NO953837D0 (no) 1995-09-28
BR9406613A (pt) 1996-02-06
NO305244B1 (no) 1999-04-26
PL310889A1 (en) 1996-01-08
EP0825184B1 (en) 2001-06-20
GB9406143D0 (en) 1994-05-18
DK0825184T3 (da) 2001-09-10
IL109144A (en) 2000-02-29
FI954616L (fi) 1995-09-28
EP0691959A1 (en) 1996-01-17
ES2119184T3 (es) 1998-10-01

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