TW276254B - - Google Patents

Info

Publication number
TW276254B
TW276254B TW083102802A TW83102802A TW276254B TW 276254 B TW276254 B TW 276254B TW 083102802 A TW083102802 A TW 083102802A TW 83102802 A TW83102802 A TW 83102802A TW 276254 B TW276254 B TW 276254B
Authority
TW
Taiwan
Prior art keywords
ylüphenoxybutyric
piperazin
fibrinogen
iiia
pyridyl
Prior art date
Application number
TW083102802A
Other languages
English (en)
Chinese (zh)
Inventor
George Brewster Andrew
Eden Shute Richard
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939306453A external-priority patent/GB9306453D0/en
Priority claimed from GB939325605A external-priority patent/GB9325605D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Application granted granted Critical
Publication of TW276254B publication Critical patent/TW276254B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electroluminescent Light Sources (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW083102802A 1993-03-29 1994-03-28 TW276254B (enExample)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939306453A GB9306453D0 (en) 1993-03-29 1993-03-29 Heterocyclic derivatives
GB939325605A GB9325605D0 (en) 1993-12-15 1993-12-15 Heterocyclic derivatives
GB9406143A GB9406143D0 (en) 1993-03-29 1994-03-28 Heterocyclic derivatives

Publications (1)

Publication Number Publication Date
TW276254B true TW276254B (enExample) 1996-05-21

Family

ID=26302668

Family Applications (1)

Application Number Title Priority Date Filing Date
TW083102802A TW276254B (enExample) 1993-03-29 1994-03-28

Country Status (26)

Country Link
US (1) US5556977A (enExample)
EP (2) EP0825184B1 (enExample)
JP (1) JPH08508291A (enExample)
KR (1) KR100231089B1 (enExample)
CN (1) CN1120334A (enExample)
AT (2) ATE168678T1 (enExample)
AU (1) AU692438B2 (enExample)
BR (1) BR9406613A (enExample)
CA (1) CA2156070A1 (enExample)
CZ (1) CZ250995A3 (enExample)
DE (2) DE69411900T2 (enExample)
DK (2) DK0825184T3 (enExample)
ES (2) ES2119184T3 (enExample)
FI (1) FI954616L (enExample)
GB (1) GB9406143D0 (enExample)
GR (2) GR3027751T3 (enExample)
HU (2) HUT72088A (enExample)
IL (1) IL109144A (enExample)
NO (1) NO305244B1 (enExample)
NZ (1) NZ262941A (enExample)
PL (1) PL310889A1 (enExample)
PT (1) PT825184E (enExample)
SK (1) SK120895A3 (enExample)
TW (1) TW276254B (enExample)
WO (1) WO1994022834A1 (enExample)
ZW (1) ZW4294A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202011000090U1 (de) 2011-01-14 2011-04-21 E-LEAD ELECTRONIC CO., LTD., Shengang Shiang Fahrzeug-Audiosystem mit auswechselbarem Plug-In-Computer

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US5700801A (en) * 1994-12-23 1997-12-23 Karl Thomae, Gmbh Piperazine derivatives, pharmaceutical compositions containing these compounds, their use and processes for preparing them
FR2734818B1 (fr) * 1995-06-01 1998-07-10 Zeneca Ltd Acide (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazine-1-yl- phenoxy}-butyrique, procede pour sa preparation et composition pharmaceutique le contenant
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ATE242774T1 (de) 1997-02-13 2003-06-15 Astrazeneca Ab Heterozyklische verbindungen die als oxido- squalen-zyklase-inhibitoren anwendung finden
GB9715895D0 (en) 1997-07-29 1997-10-01 Zeneca Ltd Heterocyclic compounds
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JP2002516305A (ja) 1998-05-12 2002-06-04 アメリカン・ホーム・プロダクツ・コーポレイション インスリン抵抗性および高血糖症の治療に有用な２，３，５−置換ビフェニル
US6451827B2 (en) 1998-05-12 2002-09-17 Wyeth 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia
US6166069A (en) * 1998-05-12 2000-12-26 American Home Products Corporation Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
US6221902B1 (en) 1998-05-12 2001-04-24 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
US6699896B1 (en) 1998-05-12 2004-03-02 Wyeth Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
CA2338745A1 (en) * 1998-07-31 2000-02-10 Hamideh Zarrinmayeh Heterocyclyl sulphonamide derivatives
GB9902989D0 (en) 1999-02-11 1999-03-31 Zeneca Ltd Heterocyclic derivatives
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US6310081B1 (en) 1999-05-10 2001-10-30 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
ATE502928T1 (de) 2000-11-01 2011-04-15 Millennium Pharm Inc Stickstoffhaltige heterozyklische verbindungen und verfahren zu deren herstellung
SG11202002032SA (en) 2017-09-22 2020-04-29 Jubilant Epipad LLC Heterocyclic compounds as pad inhibitors
CN111225915B (zh) 2017-10-18 2023-03-07 朱比兰特埃皮帕德有限公司 作为pad抑制剂的咪唑并吡啶化合物
AU2018362046B2 (en) 2017-11-06 2023-04-13 Jubilant Prodel LLC Pyrimidine derivatives as inhibitors of PD1/PD-L1 activation
AU2018372211B2 (en) 2017-11-24 2023-02-02 Jubilant Episcribe LLC, Heterocyclic compounds as PRMT5 inhibitors
CA3093527A1 (en) 2018-03-13 2019-09-19 Jubilant Prodel LLC Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202011000090U1 (de) 2011-01-14 2011-04-21 E-LEAD ELECTRONIC CO., LTD., Shengang Shiang Fahrzeug-Audiosystem mit auswechselbarem Plug-In-Computer

Also Published As

Publication number Publication date
ZW4294A1 (en) 1994-12-21
SK120895A3 (en) 1996-06-05
CZ250995A3 (en) 1996-01-17
CN1120334A (zh) 1996-04-10
DK0691959T3 (da) 1999-04-26
DE69427548D1 (de) 2001-07-26
HUT72088A (en) 1996-03-28
FI954616A7 (fi) 1995-09-28
AU6288994A (en) 1994-10-24
ES2159798T3 (es) 2001-10-16
ATE202345T1 (de) 2001-07-15
DE69411900T2 (de) 1998-12-10
KR100231089B1 (ko) 1999-11-15
PT825184E (pt) 2001-11-30
HU211336A9 (en) 1995-11-28
EP0691959B1 (en) 1998-07-22
GR3027751T3 (en) 1998-11-30
NZ262941A (en) 1997-07-27
NO953837L (no) 1995-09-28
CA2156070A1 (en) 1994-10-13
FI954616A0 (fi) 1995-09-28
EP0825184A1 (en) 1998-02-25
IL109144A0 (en) 1994-06-24
JPH08508291A (ja) 1996-09-03
HU9502290D0 (en) 1995-10-30
DE69427548T2 (de) 2002-04-18
ATE168678T1 (de) 1998-08-15
US5556977A (en) 1996-09-17
WO1994022834A1 (en) 1994-10-13
AU692438B2 (en) 1998-06-11
GR3036640T3 (en) 2001-12-31
DE69411900D1 (de) 1998-08-27
NO953837D0 (no) 1995-09-28
BR9406613A (pt) 1996-02-06
NO305244B1 (no) 1999-04-26
PL310889A1 (en) 1996-01-08
EP0825184B1 (en) 2001-06-20
GB9406143D0 (en) 1994-05-18
DK0825184T3 (da) 2001-09-10
IL109144A (en) 2000-02-29
FI954616L (fi) 1995-09-28
EP0691959A1 (en) 1996-01-17
ES2119184T3 (es) 1998-10-01

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