DE69126978D1 - Derivate des 6-amino-octahydro-indolizintriols - Google Patents

Derivate des 6-amino-octahydro-indolizintriols

Info

Publication number
DE69126978D1
DE69126978D1 DE69126978T DE69126978T DE69126978D1 DE 69126978 D1 DE69126978 D1 DE 69126978D1 DE 69126978 T DE69126978 T DE 69126978T DE 69126978 T DE69126978 T DE 69126978T DE 69126978 D1 DE69126978 D1 DE 69126978D1
Authority
DE
Germany
Prior art keywords
amino
octahydro
derivatives
indolizintriol
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69126978T
Other languages
English (en)
Other versions
DE69126978T2 (de
Inventor
Paul Liu
Mohinder Kang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69126978D1 publication Critical patent/DE69126978D1/de
Publication of DE69126978T2 publication Critical patent/DE69126978T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE69126978T 1990-06-04 1991-05-08 Derivate des 6-amino-octahydro-indolizintriols Expired - Lifetime DE69126978T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/532,522 US5079254A (en) 1990-06-04 1990-06-04 Derivatives of 6-aminooctahydroindolizinetriol
PCT/US1991/003179 WO1991018598A1 (en) 1990-06-04 1991-05-08 Derivatives of 6-aminooctahydroindolizinetriol

Publications (2)

Publication Number Publication Date
DE69126978D1 true DE69126978D1 (de) 1997-08-28
DE69126978T2 DE69126978T2 (de) 1997-11-27

Family

ID=24122149

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69126978T Expired - Lifetime DE69126978T2 (de) 1990-06-04 1991-05-08 Derivate des 6-amino-octahydro-indolizintriols

Country Status (15)

Country Link
US (1) US5079254A (de)
EP (1) EP0532530B1 (de)
JP (1) JP3019265B2 (de)
KR (1) KR100195421B1 (de)
AT (1) ATE155685T1 (de)
AU (1) AU641771B2 (de)
CA (1) CA2082820C (de)
DE (1) DE69126978T2 (de)
DK (1) DK0532530T3 (de)
ES (1) ES2106080T3 (de)
FI (1) FI97226C (de)
GR (1) GR3025044T3 (de)
HU (1) HU212579B (de)
NO (1) NO300686B1 (de)
WO (1) WO1991018598A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995013538A1 (en) * 1993-11-12 1995-05-18 Operon Technologies, Inc. Methods of producing and screening complex chemical libraries
AU1562895A (en) * 1994-01-12 1995-08-01 Massachusetts Institute Of Technology Process for making xanthene or cubane based compounds, and protease inhibitors
EP1633356A1 (de) * 2003-05-22 2006-03-15 The Hospital for Sick Children Behandlung von tay sachs oder sandhoff erkrankungen durch erhöhung der hexosaminidase aktivität
EP1713485A4 (de) * 2004-01-20 2007-09-19 Optimer Pharmaceuticals Inc Behandlung von degenerativen knorpelerkrankungen in einem säugetier mit glycosidase-hemmern
KR100858512B1 (ko) 2007-03-29 2008-09-12 포항공과대학교 산학협력단 헥소스아미니데이즈 활성 저해 방법
AU2009276222B2 (en) * 2008-08-01 2015-03-05 Simon Fraser University Selective glycosidase inhibitors and uses thereof
JP5861194B2 (ja) 2010-12-23 2016-02-16 アレクトス・セラピューティクス・インコーポレイテッド 選択的グルコシダーゼインヒビターおよびその使用
US9718854B2 (en) 2011-03-31 2017-08-01 Alectos Therapeutics Inc. Selective glycosidase inhibitors and uses thereof
US9701693B2 (en) 2011-06-27 2017-07-11 Alectos Therapeutics Inc. Selective glycosidase inhibitors and uses thereof
US9670195B2 (en) 2012-08-31 2017-06-06 Alectos Therapeutics Inc. Glycosidase inhibitors and uses thereof
US9809537B2 (en) 2012-08-31 2017-11-07 Alectos Therapeutics Inc. Glycosidase inhibitors and uses thereof
WO2014067003A1 (en) 2012-10-31 2014-05-08 Alectos Therapeutics Inc. Glycosidase inhibitors and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5973519A (ja) * 1982-09-17 1984-04-25 Fujisawa Pharmaceut Co Ltd スワインソニンの製造法およびそれを含む免疫調整剤
GB8429810D0 (en) * 1984-11-26 1985-01-03 Fujisawa Pharmaceutical Co Indolizidine derivatives
JPS61277685A (ja) * 1985-05-31 1986-12-08 Fujisawa Pharmaceut Co Ltd 新規インドリジジン誘導体、その製造法およびそれを含有する組成物
DE3620645A1 (de) * 1985-12-20 1987-07-02 Bayer Ag 3-amino-4,5-dihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung
CA1315276C (en) * 1987-07-02 1993-03-30 Paul S. Liu Castanospermine esters and glycosides
JPH01129182A (ja) * 1987-11-16 1989-05-22 Tokyo Keiki Co Ltd 波動伝搬時間測定装置
JPH01277685A (ja) * 1988-04-28 1989-11-08 Hitachi Ltd ピストンポンプ

Also Published As

Publication number Publication date
EP0532530A1 (de) 1993-03-24
DK0532530T3 (da) 1997-08-25
FI925260A (fi) 1992-11-19
AU641771B2 (en) 1993-09-30
CA2082820C (en) 2002-01-22
DE69126978T2 (de) 1997-11-27
GR3025044T3 (en) 1998-01-30
HUT62585A (en) 1993-05-28
ES2106080T3 (es) 1997-11-01
ATE155685T1 (de) 1997-08-15
HU9203829D0 (en) 1993-03-29
NO924670L (no) 1992-12-03
AU7874391A (en) 1991-12-31
JP3019265B2 (ja) 2000-03-13
CA2082820A1 (en) 1991-12-05
US5079254A (en) 1992-01-07
FI925260A0 (fi) 1992-11-19
FI97226C (fi) 1996-11-11
JPH05507474A (ja) 1993-10-28
EP0532530A4 (en) 1993-05-26
KR930700502A (ko) 1993-03-15
EP0532530B1 (de) 1997-07-23
WO1991018598A1 (en) 1991-12-12
FI97226B (fi) 1996-07-31
NO300686B1 (no) 1997-07-07
HU212579B (en) 1996-08-29
NO924670D0 (no) 1992-12-03
KR100195421B1 (ko) 1999-06-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS INC. (N.D.GES.D. STAATES PENNSYLVANIA), GR

8327 Change in the person/name/address of the patent owner

Owner name: AVENTISUB II INC., GREENVILLE, DEL., US