ATE144551T1 - Methode zur produktion von glukagon - Google Patents

Methode zur produktion von glukagon

Info

Publication number
ATE144551T1
ATE144551T1 AT90300937T AT90300937T ATE144551T1 AT E144551 T1 ATE144551 T1 AT E144551T1 AT 90300937 T AT90300937 T AT 90300937T AT 90300937 T AT90300937 T AT 90300937T AT E144551 T1 ATE144551 T1 AT E144551T1
Authority
AT
Austria
Prior art keywords
glucagon
fusion protein
glu
glutamic acid
producing
Prior art date
Application number
AT90300937T
Other languages
English (en)
Inventor
Jun Ishizaki
Mikio Tamaki
Masaru Shin
Hiroshi Teraoka
Nobuo Yoshida
Hiroshige Tsuzuki
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of ATE144551T1 publication Critical patent/ATE144551T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Diaphragms And Bellows (AREA)
  • Separation By Low-Temperature Treatments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Earth Drilling (AREA)
  • Control Of El Displays (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT90300937T 1989-02-01 1990-01-30 Methode zur produktion von glukagon ATE144551T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2415889 1989-02-01

Publications (1)

Publication Number Publication Date
ATE144551T1 true ATE144551T1 (de) 1996-11-15

Family

ID=12130531

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90300937T ATE144551T1 (de) 1989-02-01 1990-01-30 Methode zur produktion von glukagon

Country Status (18)

Country Link
EP (1) EP0381433B1 (de)
JP (1) JPH0748999B2 (de)
KR (1) KR0161656B1 (de)
CN (1) CN1063795C (de)
AT (1) ATE144551T1 (de)
BR (1) BR9000445A (de)
CA (1) CA2008824C (de)
DE (1) DE69028935T2 (de)
DK (1) DK0381433T3 (de)
ES (1) ES2095236T3 (de)
FI (1) FI900497A0 (de)
GR (1) GR3021965T3 (de)
HU (1) HUT54410A (de)
IL (1) IL93173A0 (de)
NO (1) NO900410L (de)
NZ (1) NZ232255A (de)
PT (1) PT93031A (de)
ZA (1) ZA90533B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506595B2 (en) * 1998-03-31 2003-01-14 Itoham Foods Inc. DNAs encoding new fusion proteins and processes for preparing useful polypeptides through expression of the DNAs
CN100480374C (zh) * 2001-09-28 2009-04-22 中国科学院上海生命科学研究院 制备重组人类胰高血糖素肽－1氨基酸7－37肽段的方法
JP6054861B2 (ja) * 2010-03-26 2016-12-27 ノヴォ ノルディスク アー／エス 新規のグルカゴン類似体
BR112014006684A2 (pt) 2011-09-23 2017-03-28 Novo Nordisk As análogos de glucagon
BR112015025464A2 (pt) 2013-04-18 2017-10-10 Novo Nordisk As coagonistas do receptor de glp-1/glucagon estáveis, prolongados para uso médico
US10570184B2 (en) 2014-06-04 2020-02-25 Novo Nordisk A/S GLP-1/glucagon receptor co-agonists for medical use
CN104593399A (zh) * 2014-12-22 2015-05-06 广西大学 一种转基因胰岛素的合成工艺

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK27885A (da) * 1985-01-22 1986-07-23 Novo Industri As Fremstilling af peptider
US4743679A (en) * 1986-02-24 1988-05-10 Creative Biomolecules, Inc. Process for producing human epidermal growth factor and analogs thereof

Also Published As

Publication number Publication date
CN1046559A (zh) 1990-10-31
AU634999B2 (en) 1993-03-11
CA2008824C (en) 1997-08-05
KR900013077A (ko) 1990-09-03
PT93031A (pt) 1990-08-31
CA2008824A1 (en) 1990-08-01
EP0381433B1 (de) 1996-10-23
EP0381433A1 (de) 1990-08-08
JPH03254692A (ja) 1991-11-13
DE69028935T2 (de) 1997-03-06
GR3021965T3 (en) 1997-03-31
HUT54410A (en) 1991-02-28
KR0161656B1 (ko) 1998-11-16
DK0381433T3 (da) 1996-11-18
NO900410D0 (no) 1990-01-29
ZA90533B (en) 1990-10-31
NO900410L (no) 1990-08-02
HU900614D0 (en) 1990-04-28
ES2095236T3 (es) 1997-02-16
JPH0748999B2 (ja) 1995-05-31
NZ232255A (en) 1992-03-26
DE69028935D1 (de) 1996-11-28
IL93173A0 (en) 1990-11-05
AU4898990A (en) 1990-08-09
CN1063795C (zh) 2001-03-28
BR9000445A (pt) 1991-01-15
FI900497A0 (fi) 1990-01-31

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee